CA2350066A1 - Benzylmaltosides acetal utilises comme inhibiteurs de la proliferation cellulaire des muscles lisses - Google Patents

Benzylmaltosides acetal utilises comme inhibiteurs de la proliferation cellulaire des muscles lisses Download PDF

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Publication number
CA2350066A1
CA2350066A1 CA002350066A CA2350066A CA2350066A1 CA 2350066 A1 CA2350066 A1 CA 2350066A1 CA 002350066 A CA002350066 A CA 002350066A CA 2350066 A CA2350066 A CA 2350066A CA 2350066 A1 CA2350066 A1 CA 2350066A1
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CA
Canada
Prior art keywords
carbon atoms
phenyl
chloro
methyl
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002350066A
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English (en)
Inventor
Scott Christian Mayer
Paul Jeffrey Dollings
Robert Emmett Mcdevitt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2350066A1 publication Critical patent/CA2350066A1/fr
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Vascular Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cardiology (AREA)
  • Saccharide Compounds (AREA)

Abstract

La présente invention concerne des inhibiteurs de la prolifération cellulaire des muscles lisses représentés par la formule (I), dans laquelle X, R?1¿, R?2¿, R?3¿, R?4¿, R?5¿ R?6¿, R?7¿, sont tels que décrits dans le descriptif et les revendications.
CA002350066A 1998-11-24 1999-11-23 Benzylmaltosides acetal utilises comme inhibiteurs de la proliferation cellulaire des muscles lisses Abandoned CA2350066A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19880398A 1998-11-24 1998-11-24
US09/198,803 1998-11-24
PCT/US1999/027828 WO2000031096A1 (fr) 1998-11-24 1999-11-23 Benzylmaltosides acetal utilises comme inhibiteurs de la proliferation cellulaire des muscles lisses

Publications (1)

Publication Number Publication Date
CA2350066A1 true CA2350066A1 (fr) 2000-06-02

Family

ID=22734926

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002350066A Abandoned CA2350066A1 (fr) 1998-11-24 1999-11-23 Benzylmaltosides acetal utilises comme inhibiteurs de la proliferation cellulaire des muscles lisses

Country Status (7)

Country Link
EP (1) EP1133509A1 (fr)
JP (1) JP2002530421A (fr)
CN (1) CN1328566A (fr)
AU (1) AU1633000A (fr)
BR (1) BR9915965A (fr)
CA (1) CA2350066A1 (fr)
WO (1) WO2000031096A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1133510A2 (fr) * 1998-11-24 2001-09-19 American Home Products Corporation Benzylmaltosides acyles, inhibiteurs de proliferation des cellules des muscles lisses
CN103360437B (zh) * 2013-04-27 2015-10-21 江苏教育学院 一种硫辛酸糖类衍生物及其制备方法和在制备抗肿瘤药物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL115745A (en) * 1994-11-07 2000-11-21 American Home Prod Acylated benzylglycosides and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EP1133509A1 (fr) 2001-09-19
WO2000031096A1 (fr) 2000-06-02
CN1328566A (zh) 2001-12-26
BR9915965A (pt) 2001-08-21
JP2002530421A (ja) 2002-09-17
AU1633000A (en) 2000-06-13

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Legal Events

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FZDE Dead