CA2348841C - Compositions ameliorees stimulant la croissance - Google Patents

Compositions ameliorees stimulant la croissance Download PDF

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Publication number
CA2348841C
CA2348841C CA002348841A CA2348841A CA2348841C CA 2348841 C CA2348841 C CA 2348841C CA 002348841 A CA002348841 A CA 002348841A CA 2348841 A CA2348841 A CA 2348841A CA 2348841 C CA2348841 C CA 2348841C
Authority
CA
Canada
Prior art keywords
formulation
release
controlled
agent
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002348841A
Other languages
English (en)
Other versions
CA2348841A1 (fr
Inventor
Chung Shih
Thomas J. Kennedy
Peter James Knight
Daniel S. Robins
Zezhi Jesse Shao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of CA2348841A1 publication Critical patent/CA2348841A1/fr
Application granted granted Critical
Publication of CA2348841C publication Critical patent/CA2348841C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Fodder In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Feed For Specific Animals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Agent amélioré stimulant la croissance et la prise de poids pour des animaux domestiques, tels que les bovins, les porcs et les moutons, constitué d'un anabolisant administré par voie sous-cutanée sous forme d'une composition implantée à double libération. Les gains de croissance et de poids sont particulièrement accrus lorsque du zéranol est administré sous forme de composition à libération immédiate puis à libération prolongée, ce qui permet l'injection de la dose en une seule fois.
CA002348841A 1998-11-04 1999-11-02 Compositions ameliorees stimulant la croissance Expired - Lifetime CA2348841C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18594498A 1998-11-04 1998-11-04
US09/185,944 1998-11-04
PCT/US1999/023993 WO2000025743A2 (fr) 1998-11-04 1999-11-02 Compositions ameliorees stimulant la croissance

Publications (2)

Publication Number Publication Date
CA2348841A1 CA2348841A1 (fr) 2000-05-11
CA2348841C true CA2348841C (fr) 2007-04-17

Family

ID=22683037

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002348841A Expired - Lifetime CA2348841C (fr) 1998-11-04 1999-11-02 Compositions ameliorees stimulant la croissance

Country Status (11)

Country Link
AR (1) AR025133A1 (fr)
AU (1) AU777393B2 (fr)
BR (2) BR9914996A (fr)
CA (1) CA2348841C (fr)
CO (1) CO5140100A1 (fr)
CR (1) CR6351A (fr)
MY (1) MY134868A (fr)
PE (1) PE20001092A1 (fr)
TW (1) TWI250027B (fr)
WO (1) WO2000025743A2 (fr)
ZA (1) ZA200103494B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020131988A1 (en) * 1999-12-16 2002-09-19 Foster Todd P. Pharmaceutical implant containing immediate-release and sustained-release components and method of administration
US6953586B1 (en) * 2000-06-08 2005-10-11 Ivy Animal Health, Inc. Growth promoting pharmaceutical implant
EP4000688A1 (fr) 2020-11-19 2022-05-25 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Procédé pour la préparation d'acétate trenbolone ayant une distribution granulométrique définie
EP4001288A1 (fr) 2020-11-19 2022-05-25 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Procédé de préparation d'acétate de trenbolone présentant une distribution granulométrique définie et un habitus cristallin à plaques irrégulières hexagonales
EP4001289B1 (fr) 2020-11-19 2023-05-03 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Procédé amélioré de préparation de trenbolone et/ou d'acétate de trenbolone

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2573307B1 (fr) * 1984-11-22 1988-06-10 Virbac Ctre Rech Biolog Implants anabolisants a liberation prolongee
US4670249A (en) * 1985-04-12 1987-06-02 International Minerals & Chemical Corp. Growth-promoting compositions
US5219572A (en) * 1989-03-17 1993-06-15 Pitman-Moore, Inc. Controlled release delivery device for macromolecular proteins
US5747060A (en) * 1996-03-26 1998-05-05 Euro-Celtique, S.A. Prolonged local anesthesia with colchicine
US5874098A (en) * 1997-05-28 1999-02-23 Ivy Laboratories, Inc. Pellet implant system

Also Published As

Publication number Publication date
CA2348841A1 (fr) 2000-05-11
BRPI9914996B8 (pt) 2021-07-06
AR025133A1 (es) 2002-11-13
BR9914996A (pt) 2001-07-10
WO2000025743A3 (fr) 2000-08-24
AU777393B2 (en) 2004-10-14
WO2000025743A2 (fr) 2000-05-11
BRPI9914996A (pt) 2001-07-10
PE20001092A1 (es) 2000-10-31
ZA200103494B (en) 2002-07-30
BRPI9914996B1 (pt) 2011-11-01
TWI250027B (en) 2006-03-01
CO5140100A1 (es) 2002-03-22
MY134868A (en) 2007-12-31
AU3096700A (en) 2000-05-22
CR6351A (es) 2003-11-20

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MKEX Expiry

Effective date: 20191104