CA2348757A1 - Polypeptides secretes et transmembranaires et acides nucleiques codant pour ceux-ci - Google Patents

Polypeptides secretes et transmembranaires et acides nucleiques codant pour ceux-ci Download PDF

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Publication number
CA2348757A1
CA2348757A1 CA002348757A CA2348757A CA2348757A1 CA 2348757 A1 CA2348757 A1 CA 2348757A1 CA 002348757 A CA002348757 A CA 002348757A CA 2348757 A CA2348757 A CA 2348757A CA 2348757 A1 CA2348757 A1 CA 2348757A1
Authority
CA
Canada
Prior art keywords
seq
polypeptide
sequence identity
amino acid
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002348757A
Other languages
English (en)
Inventor
David Botstein
Luc Desnoyers
Napoleone Ferrara
Sherman Fong
Wei-Qiang Gao
Audrey Goddard
Austin L. Gurney
James Pan
Margaret Ann Roy
Timothy A. Stewart
Daniel Tumas
Colin K. Watanabe
William I. Wood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1999/012252 external-priority patent/WO1999063088A2/fr
Application filed by Individual filed Critical Individual
Priority to CA002405945A priority Critical patent/CA2405945A1/fr
Priority to CA002407803A priority patent/CA2407803A1/fr
Priority to CA002406256A priority patent/CA2406256A1/fr
Priority to CA002405791A priority patent/CA2405791A1/fr
Publication of CA2348757A1 publication Critical patent/CA2348757A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention a trait à de nouveaux polypeptides et à des molécules d'acides nucléiques codant pour ces polypeptides. L'invention concerne également des vecteurs et des cellules hôtes contenant ces séquences d'acides nucléiques, des molécules polypeptidiques chimères contenant les polypeptides de l'invention fusionnés à des séquences polypeptidiques hétérologues, des anticorps qui se lient aux polypeptides de la présente invention et des procédés de production des polypeptides de l'invention.
CA002348757A 1998-12-16 1999-12-01 Polypeptides secretes et transmembranaires et acides nucleiques codant pour ceux-ci Abandoned CA2348757A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002405945A CA2405945A1 (fr) 1998-12-16 1999-12-01 Polypeptides secretes et transmembranaires et acides nucleiques codant pour ceux-ci
CA002407803A CA2407803A1 (fr) 1999-02-12 1999-12-01 Polypeptides secretes et transmembranaires et acides nucleiques codant pour ceux-ci
CA002406256A CA2406256A1 (fr) 1999-01-12 1999-12-01 Polypeptides secretes et transmembranaires et acides nucleiques codant pour ceux-ci
CA002405791A CA2405791A1 (fr) 1999-02-10 1999-12-01 Polypeptides secretes et transmembrainaires et acides nucleiques codant pour ceux-ci

Applications Claiming Priority (21)

Application Number Priority Date Filing Date Title
US11314598P 1998-12-16 1998-12-16
US11285198P 1998-12-16 1998-12-16
US60/112,851 1998-12-16
US60/113,145 1998-12-16
US11351198P 1998-12-22 1998-12-22
US60/113,511 1998-12-22
US11573399P 1999-01-12 1999-01-12
US11555899P 1999-01-12 1999-01-12
US11556599P 1999-01-12 1999-01-12
US60/115,733 1999-01-12
US60/115,565 1999-01-12
US60/115,558 1999-01-12
US11934199P 1999-02-09 1999-02-09
US60/119,341 1999-02-09
US11953799P 1999-02-10 1999-02-10
US60/119,537 1999-02-10
US11996599P 1999-02-12 1999-02-12
US60/119,965 1999-02-12
USPCT/US99/12252 1999-06-02
PCT/US1999/012252 WO1999063088A2 (fr) 1998-06-02 1999-06-02 Proteines membranaires et acides nucleiques codant ces proteines
PCT/US1999/028634 WO2000036102A2 (fr) 1998-12-16 1999-12-01 Polypeptides secretes et transmembranaires et acides nucleiques codant pour ceux-ci

Related Child Applications (4)

Application Number Title Priority Date Filing Date
CA002405945A Division CA2405945A1 (fr) 1998-12-16 1999-12-01 Polypeptides secretes et transmembranaires et acides nucleiques codant pour ceux-ci
CA002405791A Division CA2405791A1 (fr) 1999-02-10 1999-12-01 Polypeptides secretes et transmembrainaires et acides nucleiques codant pour ceux-ci
CA002407803A Division CA2407803A1 (fr) 1999-02-12 1999-12-01 Polypeptides secretes et transmembranaires et acides nucleiques codant pour ceux-ci
CA002406256A Division CA2406256A1 (fr) 1999-01-12 1999-12-01 Polypeptides secretes et transmembranaires et acides nucleiques codant pour ceux-ci

Publications (1)

Publication Number Publication Date
CA2348757A1 true CA2348757A1 (fr) 2000-06-22

Family

ID=27578476

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002348757A Abandoned CA2348757A1 (fr) 1998-12-16 1999-12-01 Polypeptides secretes et transmembranaires et acides nucleiques codant pour ceux-ci

Country Status (8)

Country Link
EP (1) EP1141285A2 (fr)
JP (5) JP2003521229A (fr)
KR (2) KR100468977B1 (fr)
AU (7) AU777006B2 (fr)
CA (1) CA2348757A1 (fr)
IL (11) IL142794A0 (fr)
MX (1) MXPA01006057A (fr)
WO (1) WO2000036102A2 (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020137890A1 (en) 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US8088386B2 (en) 1998-03-20 2012-01-03 Genentech, Inc. Treatment of complement-associated disorders
US7192589B2 (en) 1998-09-16 2007-03-20 Genentech, Inc. Treatment of inflammatory disorders with STIgMA immunoadhesins
US8007798B2 (en) 1997-11-21 2011-08-30 Genentech, Inc. Treatment of complement-associated disorders
US7419663B2 (en) 1998-03-20 2008-09-02 Genentech, Inc. Treatment of complement-associated disorders
US6914130B2 (en) * 1998-06-17 2005-07-05 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
AU2008201101B2 (en) * 1999-03-11 2011-01-20 Merck Serono Sa Vascular adhesion molecules and modulation of their function
EE05497B1 (et) * 1999-03-11 2011-12-15 Rmf Dictagene S.A. Polüpeptiid, lahustuv CRAM-1 polüpeptiid, polünukleotiid ja antikeha
KR100543857B1 (ko) * 1999-09-01 2006-01-23 제넨테크, 인크. 혈관신생 및 심혈관형성의 촉진 또는 억제
DE19947010A1 (de) * 1999-09-30 2001-04-05 Universitaetsklinikum Freiburg Das Gen PRV-1 und dessen Verwendung
US20020006653A1 (en) * 2000-04-28 2002-01-17 Meyers Rachel A. 25692, a novel human O-Methyltransferase family member and uses thereof
GB0110273D0 (en) * 2001-04-26 2001-06-20 Inpharmatica Ltd Novel proteins
WO2003053334A2 (fr) * 2001-12-19 2003-07-03 Genentech, Inc. Compositions et methodes de diagnostic et de traitement de tumeur
US20070191402A1 (en) * 2002-05-17 2007-08-16 Kyowa Hakko Kogyo Co., Ltd. Method of searching substrate having antidiabetic activity
JP2006501290A (ja) * 2002-10-02 2006-01-12 デヴェロゲン アクチエンゲゼルシャフト フュア エントヴィックルングスビオローギッシェ フォルシュング エネルギー恒常性の調節に関与するＭｉｐｐ１相同性を有する核酸およびタンパク質
CN107929731A (zh) 2005-11-04 2018-04-20 健泰科生物技术公司 利用补体途径抑制剂治疗眼部疾病
US8007797B2 (en) 2006-09-28 2011-08-30 Merck Serono S.A. Junctional adhesion molecule-C (JAM-C) binding compounds and methods of their use
ES2700609T3 (es) 2006-11-02 2019-02-18 Genentech Inc Anticuerpos anti-factor D humanizados y sus usos
AR066660A1 (es) 2007-05-23 2009-09-02 Genentech Inc Prevencion y tratamiento de condiciones del ojo asociadas con su complemento
CR20170001A (es) 2008-04-28 2017-08-10 Genentech Inc Anticuerpos anti factor d humanizados
BRPI0912003A2 (pt) 2008-05-06 2016-07-12 Genentech Inc afinidade de variantes de crig maturadas
KR20180021234A (ko) 2013-08-12 2018-02-28 제넨테크, 인크. 보체-연관 상태의 치료를 위한 조성물 및 방법
WO2015168468A1 (fr) 2014-05-01 2015-11-05 Genentech, Inc. Variants d'anticorps anti-facteur d et leurs utilisations
EP3368090A1 (fr) 2015-10-30 2018-09-05 H. Hoffnabb-La Roche Ag Conjugués de variants d'anticorps anti-facteur d et leurs utilisations

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001970A (en) * 1994-11-07 1999-12-14 Merck & Co., Inc Modified human neuropeptide Y1 Receptors
WO1997025427A1 (fr) * 1996-01-12 1997-07-17 Genetics Institute, Inc. Beta-chemokine, h1305 (mpc-2)
JP3646191B2 (ja) * 1996-03-19 2005-05-11 大塚製薬株式会社 ヒト遺伝子
WO1998050552A1 (fr) * 1997-05-06 1998-11-12 Zymogenetics, Inc. Nouveaux antigenes tumoraux
DE19818620A1 (de) * 1998-04-21 1999-10-28 Metagen Gesellschaft Fuer Genomforschung Mbh Menschliche Nukleinsäuresequenzen aus Blase-Normal
WO2000000610A2 (fr) * 1998-06-26 2000-01-06 Incyte Pharmaceuticals, Inc. Proteines contenant un peptide signal humain
WO2000004135A2 (fr) * 1998-07-16 2000-01-27 Incyte Pharmaceuticals, Inc. Molecules apparentees a l'alcool-deshydrogenase chaine courte de type humain, scrm-1 et scrm-2
DE19849044A1 (de) * 1998-10-23 2000-04-27 Univ Ludwigs Albert Das Gen PRV-1 und dessen Verwendung
WO2000029583A2 (fr) * 1998-11-19 2000-05-25 Incyte Pharmaceuticals, Inc. Proteines de la superfamille des immunoglobulines
JP2004520003A (ja) * 1999-03-08 2004-07-08 ジェネンテック・インコーポレーテッド 腫瘍治療のための組成物及び方法

Also Published As

Publication number Publication date
KR20010101224A (ko) 2001-11-14
JP2004041217A (ja) 2004-02-12
AU2004237922B2 (en) 2007-09-06
MXPA01006057A (es) 2003-09-10
KR100468978B1 (ko) 2005-02-02
KR100468977B1 (ko) 2005-02-02
AU2004237842A1 (en) 2005-01-13
IL200883A0 (en) 2010-05-17
AU2004237922A1 (en) 2005-01-13
AU2004237921A1 (en) 2005-01-13
EP1141285A2 (fr) 2001-10-10
JP2003521229A (ja) 2003-07-15
IL188577A0 (en) 2008-04-13
JP2004041218A (ja) 2004-02-12
WO2000036102A2 (fr) 2000-06-22
JP2007075118A (ja) 2007-03-29
IL201001A0 (en) 2010-05-17
IL188576A0 (en) 2008-04-13
IL142794A (en) 2008-03-20
IL188580A0 (en) 2008-04-13
IL188579A0 (en) 2008-04-13
AU2004237920A1 (en) 2005-01-13
IL201030A0 (en) 2010-05-17
AU2004237842B2 (en) 2007-09-20
WO2000036102A3 (fr) 2000-11-09
AU777006B2 (en) 2004-09-30
AU2004237919A1 (en) 2005-01-13
AU1932000A (en) 2000-07-03
AU2004237919B2 (en) 2007-09-06
KR20040096629A (ko) 2004-11-16
IL188581A0 (en) 2008-04-13
IL188578A0 (en) 2008-04-13
AU2004237921B2 (en) 2007-08-23
JP2007312779A (ja) 2007-12-06
IL142794A0 (en) 2002-03-10
AU2004237923B2 (en) 2007-09-06
AU2004237923A1 (en) 2005-01-13
AU2004237920B2 (en) 2007-08-23

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued