CA2345023A1 - Peptides permettant d'attenuer les symptomes du syndrome de choc toxique staphylococcique et du choc septique - Google Patents
Peptides permettant d'attenuer les symptomes du syndrome de choc toxique staphylococcique et du choc septique Download PDFInfo
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- CA2345023A1 CA2345023A1 CA002345023A CA2345023A CA2345023A1 CA 2345023 A1 CA2345023 A1 CA 2345023A1 CA 002345023 A CA002345023 A CA 002345023A CA 2345023 A CA2345023 A CA 2345023A CA 2345023 A1 CA2345023 A1 CA 2345023A1
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- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Toxicology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Cette invention concerne des compositions et des méthodes qui protègent contre le choc toxique staphylococcique ou contre le choc septique, ou qui en atténuent la gravité. Elle concerne plus particulièrement des peptides tirés de séquences homologues de la famille des toxines d'origine staphylococcique et streptococcique, qui peuvent être des polymères et des conjugués de ces peptides. Cette invention concerne également des anticorps sériques induits par les peptides et les conjugués porteurs et leur action préventive, thérapeutique et protectrice à l'égard de la plupart, si ce n'est la totalité, des toxines d'origine staphylococcique et streptococcique. L'invention concerne également des essais et des kits de diagnostic permettant de détecter la présence de toxines d'origine staphylococcique et streptococcique, ou d'anticorps de ces toxines. De plus, elle concerne également des acides nucléiques isolés et purifiés codant pour les peptides selon l'invention et des cellules hôtes transformées codant pour ces acides nucléiques.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16830398A | 1998-10-07 | 1998-10-07 | |
| US09/168,303 | 1998-10-07 | ||
| US09/335,581 US7115268B1 (en) | 1997-04-07 | 1999-06-18 | Peptides useful for reducing symptoms of toxic shock syndrome and septic shock |
| US09/335,581 | 1999-06-18 | ||
| PCT/US1999/022180 WO2000020598A1 (fr) | 1998-10-07 | 1999-09-24 | Peptides permettant d'attenuer les symptomes du syndrome de choc toxique staphylococcique et du choc septique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2345023A1 true CA2345023A1 (fr) | 2000-04-13 |
Family
ID=26863977
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002345023A Abandoned CA2345023A1 (fr) | 1998-10-07 | 1999-09-24 | Peptides permettant d'attenuer les symptomes du syndrome de choc toxique staphylococcique et du choc septique |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1127132A1 (fr) |
| JP (1) | JP2003517445A (fr) |
| AU (1) | AU6059799A (fr) |
| CA (1) | CA2345023A1 (fr) |
| WO (1) | WO2000020598A1 (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6550882B2 (en) | 2000-11-17 | 2003-04-22 | Canon Kabushiki Kaisha | Ink jet printing apparatus |
| AU2008205376B2 (en) | 2007-01-03 | 2012-07-12 | Eisai, Inc. | High affinity antibodies that neutralize Staphylococcus enterotoxin B |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1129717B2 (fr) * | 1990-01-17 | 2013-03-06 | TERMAN, David S. | Utilisation des homologues des enterotoxines de Staphylococcus pour le traitement du cancer |
| US5935568A (en) * | 1995-05-18 | 1999-08-10 | National Jewish Medical & Research Center | Gene therapy for effector cell regulation |
| JPH11514844A (ja) * | 1995-06-07 | 1999-12-21 | リージェンツ オブ ザ ユニバーシティー オブ ミネソタ | 連鎖球菌毒素ａの突然変異体および使用方法 |
| US6075119A (en) * | 1997-04-07 | 2000-06-13 | The Rockefeller University | Peptides useful for reducing symptoms of toxic shock syndrome |
-
1999
- 1999-09-24 CA CA002345023A patent/CA2345023A1/fr not_active Abandoned
- 1999-09-24 AU AU60597/99A patent/AU6059799A/en not_active Abandoned
- 1999-09-24 EP EP99970123A patent/EP1127132A1/fr not_active Withdrawn
- 1999-09-24 WO PCT/US1999/022180 patent/WO2000020598A1/fr not_active Application Discontinuation
- 1999-09-24 JP JP2000574693A patent/JP2003517445A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000020598A9 (fr) | 2000-09-21 |
| WO2000020598A1 (fr) | 2000-04-13 |
| JP2003517445A (ja) | 2003-05-27 |
| AU6059799A (en) | 2000-04-26 |
| EP1127132A1 (fr) | 2001-08-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |