CA2331118A1 - Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia - Google Patents
Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia Download PDFInfo
- Publication number
- CA2331118A1 CA2331118A1 CA002331118A CA2331118A CA2331118A1 CA 2331118 A1 CA2331118 A1 CA 2331118A1 CA 002331118 A CA002331118 A CA 002331118A CA 2331118 A CA2331118 A CA 2331118A CA 2331118 A1 CA2331118 A1 CA 2331118A1
- Authority
- CA
- Canada
- Prior art keywords
- carbon atoms
- alkyl
- hydrogen
- aryl
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7671098A | 1998-05-12 | 1998-05-12 | |
| US09/076,710 | 1998-05-12 | ||
| PCT/US1999/010183 WO1999058511A1 (en) | 1998-05-12 | 1999-05-10 | Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2331118A1 true CA2331118A1 (en) | 1999-11-18 |
Family
ID=22133734
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002331118A Abandoned CA2331118A1 (en) | 1998-05-12 | 1999-05-10 | Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1077958A1 (ja) |
| JP (1) | JP2002514631A (ja) |
| CN (1) | CN1308618A (ja) |
| AU (1) | AU4073299A (ja) |
| CA (1) | CA2331118A1 (ja) |
| WO (1) | WO1999058511A1 (ja) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002340010A1 (en) * | 2001-09-26 | 2003-04-07 | Bayer Corporation | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors |
| US7163952B2 (en) | 2001-12-03 | 2007-01-16 | Japan Tobacco Inc. | Azole compound and medicinal use thereof |
| US7141592B2 (en) * | 2003-09-25 | 2006-11-28 | Wyeth | Substituted oxadiazolidinediones |
| CA2562075C (en) | 2004-04-20 | 2012-08-14 | Transtech Pharma, Inc. | Substituted thiazole and pyrimidine derivatives as melanocortin receptor modulators |
| AU2005277138A1 (en) | 2004-08-23 | 2006-03-02 | Wyeth Holdings Corporation | Oxazolo-naphthyl acids as plaminogen activator inhibtor type-1 (PAI-1) modulators useful in the treatment of thrombosis and cardiovascular diseases |
| EP2320738A4 (en) | 2008-08-29 | 2011-08-24 | Transtech Pharma Inc | SUBSTITUTED AMINOTHIAZOL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF AND USE THEREOF |
| CN106749169B (zh) * | 2016-11-07 | 2020-04-21 | 浙江工业大学 | 一种Ertiprotafib的手性制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58183676A (ja) * | 1982-04-19 | 1983-10-26 | Takeda Chem Ind Ltd | オキサゾ−ル誘導体 |
| EP0382199A1 (en) * | 1989-02-08 | 1990-08-16 | Takeda Chemical Industries, Ltd. | Oxazole compounds and their use |
| US5591862A (en) * | 1993-06-11 | 1997-01-07 | Takeda Chemical Industries, Ltd. | Tetrazole derivatives, their production and use |
-
1999
- 1999-05-10 EP EP99924163A patent/EP1077958A1/en not_active Withdrawn
- 1999-05-10 JP JP2000548315A patent/JP2002514631A/ja active Pending
- 1999-05-10 AU AU40732/99A patent/AU4073299A/en not_active Abandoned
- 1999-05-10 CN CN99808363A patent/CN1308618A/zh active Pending
- 1999-05-10 WO PCT/US1999/010183 patent/WO1999058511A1/en not_active Application Discontinuation
- 1999-05-10 CA CA002331118A patent/CA2331118A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999058511A1 (en) | 1999-11-18 |
| EP1077958A1 (en) | 2001-02-28 |
| CN1308618A (zh) | 2001-08-15 |
| JP2002514631A (ja) | 2002-05-21 |
| AU4073299A (en) | 1999-11-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |