CA2330719C - Synergistic compositions comprising an ascorbate and lysine for states related to extra cellular matrix degeneration - Google Patents
Synergistic compositions comprising an ascorbate and lysine for states related to extra cellular matrix degeneration Download PDFInfo
- Publication number
- CA2330719C CA2330719C CA 2330719 CA2330719A CA2330719C CA 2330719 C CA2330719 C CA 2330719C CA 2330719 CA2330719 CA 2330719 CA 2330719 A CA2330719 A CA 2330719A CA 2330719 C CA2330719 C CA 2330719C
- Authority
- CA
- Canada
- Prior art keywords
- ascorbate
- acid
- lysine
- composition
- carboxylic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 26
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 title claims abstract description 23
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 title claims abstract description 23
- 210000002744 extracellular matrix Anatomy 0.000 title claims abstract description 22
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 title claims abstract description 10
- 239000004472 Lysine Substances 0.000 title claims abstract description 10
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 title abstract description 58
- 235000010323 ascorbic acid Nutrition 0.000 title abstract description 29
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- SLXKOJJOQWFEFD-UHFFFAOYSA-N 6-aminohexanoic acid Chemical compound NCCCCCC(O)=O SLXKOJJOQWFEFD-UHFFFAOYSA-N 0.000 claims description 4
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- VGKZBAMIYUHSMU-UHFFFAOYSA-N 4-[[2-chloroethyl(nitroso)carbamoyl]amino]cyclohexane-1-carboxylic acid Chemical compound OC(=O)C1CCC(NC(=O)N(CCCl)N=O)CC1 VGKZBAMIYUHSMU-UHFFFAOYSA-N 0.000 claims description 2
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- 125000001500 prolyl group Chemical group [H]N1C([H])(C(=O)[*])C([H])([H])C([H])([H])C1([H])[H] 0.000 description 1
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- 235000010378 sodium ascorbate Nutrition 0.000 description 1
- PPASLZSBLFJQEF-RKJRWTFHSA-M sodium ascorbate Substances [Na+].OC[C@@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RKJRWTFHSA-M 0.000 description 1
- 229960005055 sodium ascorbate Drugs 0.000 description 1
- PPASLZSBLFJQEF-RXSVEWSESA-M sodium-L-ascorbate Chemical compound [Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RXSVEWSESA-M 0.000 description 1
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Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00115643A EP1068868A3 (en) | 1997-07-08 | 1997-07-08 | Synergistic compositions comprising ascorbate and lysine for states related to extracellular matrix degeneration |
| EP00115643.9 | 2000-07-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2330719A1 CA2330719A1 (en) | 2002-01-20 |
| CA2330719C true CA2330719C (en) | 2008-07-08 |
Family
ID=8169313
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2330719 Expired - Fee Related CA2330719C (en) | 1997-07-08 | 2001-01-11 | Synergistic compositions comprising an ascorbate and lysine for states related to extra cellular matrix degeneration |
Country Status (3)
| Country | Link |
|---|---|
| CA (1) | CA2330719C (cs) |
| CZ (1) | CZ2001193A3 (cs) |
| IL (1) | IL140947A (cs) |
-
2001
- 2001-01-11 CA CA 2330719 patent/CA2330719C/en not_active Expired - Fee Related
- 2001-01-16 CZ CZ2001193A patent/CZ2001193A3/cs unknown
- 2001-01-17 IL IL140947A patent/IL140947A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2330719A1 (en) | 2002-01-20 |
| IL140947A (en) | 2008-06-05 |
| IL140947A0 (en) | 2002-02-10 |
| CZ2001193A3 (cs) | 2002-03-13 |
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