CA2330049A1 - Hydroxyomeprazole compositions and uses - Google Patents
Hydroxyomeprazole compositions and uses Download PDFInfo
- Publication number
- CA2330049A1 CA2330049A1 CA002330049A CA2330049A CA2330049A1 CA 2330049 A1 CA2330049 A1 CA 2330049A1 CA 002330049 A CA002330049 A CA 002330049A CA 2330049 A CA2330049 A CA 2330049A CA 2330049 A1 CA2330049 A1 CA 2330049A1
- Authority
- CA
- Canada
- Prior art keywords
- hydroxyomeprazole
- pharmaceutically acceptable
- acceptable salt
- effective amount
- therapeutically effective
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- CMZHQFXXAAIBKE-UHFFFAOYSA-N 5'-hydroxyomeprazole Chemical compound N=1C2=CC(OC)=CC=C2NC=1S(=O)CC1=NC=C(CO)C(OC)=C1C CMZHQFXXAAIBKE-UHFFFAOYSA-N 0.000 title claims abstract description 59
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- SUBDBMMJDZJVOS-UHFFFAOYSA-N 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole Chemical compound N=1C2=CC(OC)=CC=C2NC=1S(=O)CC1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-UHFFFAOYSA-N 0.000 abstract description 19
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- 230000009467 reduction Effects 0.000 description 1
- JCTLMDWUHMACGH-UHFFFAOYSA-N s-pyridin-1-ium-1-ylthiohydroxylamine Chemical class NS[N+]1=CC=CC=C1 JCTLMDWUHMACGH-UHFFFAOYSA-N 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 239000011734 sodium Chemical class 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 239000007909 solid dosage form Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000002731 stomach secretion inhibitor Substances 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 150000003457 sulfones Chemical class 0.000 description 1
- 150000003462 sulfoxides Chemical class 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 238000011287 therapeutic dose Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 125000003396 thiol group Chemical group [H]S* 0.000 description 1
- 239000010936 titanium Chemical class 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- 239000008215 water for injection Substances 0.000 description 1
- 239000011701 zinc Chemical class 0.000 description 1
- 229910052725 zinc Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8425898P | 1998-05-05 | 1998-05-05 | |
| US60/084,258 | 1998-05-05 | ||
| PCT/US1999/009814 WO1999056746A1 (en) | 1998-05-05 | 1999-05-05 | Hydroxyomeprazole compositions and uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2330049A1 true CA2330049A1 (en) | 1999-11-11 |
Family
ID=22183810
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002330049A Abandoned CA2330049A1 (en) | 1998-05-05 | 1999-05-05 | Hydroxyomeprazole compositions and uses |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6294586B1 (enExample) |
| EP (1) | EP1082114B1 (enExample) |
| JP (1) | JP2003517434A (enExample) |
| AT (1) | ATE222764T1 (enExample) |
| AU (1) | AU748872B2 (enExample) |
| CA (1) | CA2330049A1 (enExample) |
| DE (1) | DE69902657T2 (enExample) |
| ES (1) | ES2182524T3 (enExample) |
| WO (1) | WO1999056746A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6420435B1 (en) * | 1999-11-01 | 2002-07-16 | Joe S. Wilkins, Jr. | Method for treating gastrointestinal disorders |
| US6987123B2 (en) * | 2001-07-26 | 2006-01-17 | Cadila Healthcare Limited | Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine |
| US7041706B2 (en) * | 2002-04-19 | 2006-05-09 | Wilkins Jr Joe S | Method for treating crohn's disease |
| JP2006516562A (ja) * | 2003-01-24 | 2006-07-06 | ステート オブ イスラエル、ミニストリー オブ アグリカルチャー | 抗酸化活性を増強するための相乗的な組成物及び方法 |
| WO2005032554A1 (en) | 2003-10-03 | 2005-04-14 | Astron Research Pvt. Ltd | A novel transmucosal delivery system |
| ES2281292B1 (es) * | 2006-03-08 | 2008-06-16 | Quimica Sintetica S.A. | Nuevas sales de esomeprazol. procedimiento de preparacion y composiciones farmaceuticas que las comprenden. |
-
1999
- 1999-05-05 JP JP2000546772A patent/JP2003517434A/ja active Pending
- 1999-05-05 WO PCT/US1999/009814 patent/WO1999056746A1/en not_active Ceased
- 1999-05-05 DE DE69902657T patent/DE69902657T2/de not_active Expired - Fee Related
- 1999-05-05 EP EP99922802A patent/EP1082114B1/en not_active Expired - Lifetime
- 1999-05-05 AT AT99922802T patent/ATE222764T1/de not_active IP Right Cessation
- 1999-05-05 CA CA002330049A patent/CA2330049A1/en not_active Abandoned
- 1999-05-05 ES ES99922802T patent/ES2182524T3/es not_active Expired - Lifetime
- 1999-05-05 AU AU39716/99A patent/AU748872B2/en not_active Ceased
-
2000
- 2000-10-30 US US09/699,597 patent/US6294586B1/en not_active Expired - Fee Related
-
2001
- 2001-08-10 US US09/927,954 patent/US6498171B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE222764T1 (de) | 2002-09-15 |
| DE69902657D1 (de) | 2002-10-02 |
| EP1082114B1 (en) | 2002-08-28 |
| AU748872B2 (en) | 2002-06-13 |
| US6498171B2 (en) | 2002-12-24 |
| AU3971699A (en) | 1999-11-23 |
| JP2003517434A (ja) | 2003-05-27 |
| WO1999056746A1 (en) | 1999-11-11 |
| US6294586B1 (en) | 2001-09-25 |
| DE69902657T2 (de) | 2003-04-30 |
| ES2182524T3 (es) | 2003-03-01 |
| EP1082114A1 (en) | 2001-03-14 |
| US20020010196A1 (en) | 2002-01-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |