CA2327339A1 - A method of inducing an anti-tumor response against a lung metastasis in a melanoma patient - Google Patents
A method of inducing an anti-tumor response against a lung metastasis in a melanoma patient Download PDFInfo
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- CA2327339A1 CA2327339A1 CA002327339A CA2327339A CA2327339A1 CA 2327339 A1 CA2327339 A1 CA 2327339A1 CA 002327339 A CA002327339 A CA 002327339A CA 2327339 A CA2327339 A CA 2327339A CA 2327339 A1 CA2327339 A1 CA 2327339A1
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- 108020003175 receptors Proteins 0.000 description 1
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- BOLDJAUMGUJJKM-LSDHHAIUSA-N renifolin D Natural products CC(=C)[C@@H]1Cc2c(O)c(O)ccc2[C@H]1CC(=O)c3ccc(O)cc3O BOLDJAUMGUJJKM-LSDHHAIUSA-N 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000004007 reversed phase HPLC Methods 0.000 description 1
- 230000001235 sensitizing effect Effects 0.000 description 1
- 239000012679 serum free medium Substances 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 210000001082 somatic cell Anatomy 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000003393 splenic effect Effects 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000012289 standard assay Methods 0.000 description 1
- 210000000130 stem cell Anatomy 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000020382 suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- WROMPOXWARCANT-UHFFFAOYSA-N tfa trifluoroacetic acid Chemical compound OC(=O)C(F)(F)F.OC(=O)C(F)(F)F WROMPOXWARCANT-UHFFFAOYSA-N 0.000 description 1
- 238000010257 thawing Methods 0.000 description 1
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- 229940104230 thymidine Drugs 0.000 description 1
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- 238000002054 transplantation Methods 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 230000004614 tumor growth Effects 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/00119—Melanoma antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5152—Tumor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6012—Haptens, e.g. di- or trinitrophenyl (DNP, TNP)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/80—Vaccine for a specifically defined cancer
- A61K2039/876—Skin, melanoma
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8125698P | 1998-04-09 | 1998-04-09 | |
| US60/081,256 | 1998-04-09 | ||
| PCT/US1999/007725 WO1999052546A2 (en) | 1998-04-09 | 1999-04-09 | A method of inducing an anti-tumor response against a lung metastasis in a melanoma patient |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2327339A1 true CA2327339A1 (en) | 1999-10-21 |
Family
ID=22163059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002327339A Abandoned CA2327339A1 (en) | 1998-04-09 | 1999-04-09 | A method of inducing an anti-tumor response against a lung metastasis in a melanoma patient |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1067960A2 (xx) |
| JP (1) | JP2003524583A (xx) |
| CN (1) | CN1301174A (xx) |
| AR (1) | AR020067A1 (xx) |
| AU (1) | AU3482199A (xx) |
| CA (1) | CA2327339A1 (xx) |
| PL (1) | PL366240A1 (xx) |
| WO (1) | WO1999052546A2 (xx) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2273680T3 (es) | 1999-03-16 | 2007-05-16 | Thomas Jefferson University | Conjugados de celulas de mamiferos con un hapteno y metodos de preparacion y utilizacion de los mismos. |
| JP2004507446A (ja) * | 2000-02-04 | 2004-03-11 | トーマス・ジェファーソン・ユニバーシティ | 低用量ハプテン化腫瘍細胞および腫瘍細胞抽出物の免疫治療 |
| US7297330B2 (en) | 2000-02-04 | 2007-11-20 | Thomas Jefferson University | Low dose haptenized tumor cell and tumor cell extract immunotherapy |
| AU2003243485A1 (en) | 2002-06-10 | 2003-12-22 | Avax Technologies Inc. | Cryopreservation of haptenized tumor cells |
| FR3011850B1 (fr) * | 2013-10-15 | 2018-04-06 | Cfl Biotech | Vaccin therapeutique contre le cancer a base de proteines de stress rendues immunogenes |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2222135A1 (en) * | 1995-06-07 | 1996-12-19 | Thomas Jefferson University | Hapten modified tumor cell extract and methods of treating or screening for cancer |
| EP0871480A4 (en) * | 1996-10-04 | 2001-04-04 | Univ Jefferson | T-CELLS FOR COMMUNICATING AN IMMUNE RESPONSE AND APPLICATION METHOD |
| AU2686999A (en) * | 1998-02-17 | 1999-08-30 | Thomas Jefferson University | Hapten-modified tumor cell membranes, and methods of making and using hapten-modified tumor cell membranes |
-
1999
- 1999-04-09 WO PCT/US1999/007725 patent/WO1999052546A2/en not_active Application Discontinuation
- 1999-04-09 AR ARP990101625A patent/AR020067A1/es unknown
- 1999-04-09 CA CA002327339A patent/CA2327339A1/en not_active Abandoned
- 1999-04-09 EP EP99916518A patent/EP1067960A2/en not_active Withdrawn
- 1999-04-09 PL PL99366240A patent/PL366240A1/xx unknown
- 1999-04-09 CN CN99806236A patent/CN1301174A/zh active Pending
- 1999-04-09 JP JP2000543156A patent/JP2003524583A/ja active Pending
- 1999-04-09 AU AU34821/99A patent/AU3482199A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999052546A2 (en) | 1999-10-21 |
| CN1301174A (zh) | 2001-06-27 |
| JP2003524583A (ja) | 2003-08-19 |
| PL366240A1 (en) | 2005-01-24 |
| WO1999052546A3 (en) | 1999-12-16 |
| AR020067A1 (es) | 2002-04-10 |
| AU3482199A (en) | 1999-11-01 |
| EP1067960A2 (en) | 2001-01-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |