CA2325045A1 - Gamma-aminobutyric acid derivatives containing, solid compositions and process for preparing the same - Google Patents

Gamma-aminobutyric acid derivatives containing, solid compositions and process for preparing the same Download PDF

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Publication number
CA2325045A1
CA2325045A1 CA002325045A CA2325045A CA2325045A1 CA 2325045 A1 CA2325045 A1 CA 2325045A1 CA 002325045 A CA002325045 A CA 002325045A CA 2325045 A CA2325045 A CA 2325045A CA 2325045 A1 CA2325045 A1 CA 2325045A1
Authority
CA
Canada
Prior art keywords
gamma
preparing
same
acid derivatives
aminobutyric acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002325045A
Other languages
French (fr)
Other versions
CA2325045C (en
Inventor
Akira Aomatsu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner-Lambert Company
Akira Aomatsu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=15097314&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2325045(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner-Lambert Company, Akira Aomatsu filed Critical Warner-Lambert Company
Priority claimed from PCT/US1999/010186 external-priority patent/WO1999059572A1/en
Publication of CA2325045A1 publication Critical patent/CA2325045A1/en
Application granted granted Critical
Publication of CA2325045C publication Critical patent/CA2325045C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Arrangement Of Transmissions (AREA)
  • Body Structure For Vehicles (AREA)

Abstract

The present invention provides a stabilized solid composition containing a 4-amino-3-substituted-butanoic acid derivative which can be obtained by incorporating a humectant as a stabilizer.
CA002325045A 1998-05-15 1999-05-10 Gamma-aminobutyric acid derivatives containing, solid compositions and process for preparing the same Expired - Lifetime CA2325045C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP13312298A JP3761324B2 (en) 1998-05-15 1998-05-15 Passenger rice transplanter
JP10/133112 1998-05-15
PCT/US1999/010186 WO1999059572A1 (en) 1998-05-15 1999-05-10 Gamma-aminobutyric acid derivatives containing, solid compositions and process for preparing the same

Publications (2)

Publication Number Publication Date
CA2325045A1 true CA2325045A1 (en) 1999-11-25
CA2325045C CA2325045C (en) 2005-05-03

Family

ID=15097314

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002325045A Expired - Lifetime CA2325045C (en) 1998-05-15 1999-05-10 Gamma-aminobutyric acid derivatives containing, solid compositions and process for preparing the same

Country Status (16)

Country Link
JP (1) JP3761324B2 (en)
CN (1) CN1171587C (en)
AT (1) ATE407668T1 (en)
CA (1) CA2325045C (en)
CY (1) CY1108488T1 (en)
DE (1) DE69939532D1 (en)
DK (1) DK1077691T3 (en)
EA (1) EA006553B1 (en)
EE (1) EE05530B1 (en)
EG (1) EG26287A (en)
ES (1) ES2312208T3 (en)
GE (1) GEP20032987B (en)
IL (2) IL139202A0 (en)
NZ (1) NZ507162A (en)
PT (1) PT1077691E (en)
UA (1) UA76398C2 (en)

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WO2013008182A1 (en) * 2011-07-10 2013-01-17 Mahesh Kandula Prodrugs of gaba analogs
US9303038B2 (en) 2011-09-06 2016-04-05 Cellix Bio Private Limited Compositions and methods for the treatment of epilepsy and neurological diseases
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US9434704B2 (en) 2012-05-08 2016-09-06 Cellix Bio Private Limited Compositions and methods for the treatment of neurological degenerative disorders
WO2013168025A1 (en) 2012-05-08 2013-11-14 Mahesh Kandula Compositions and methods for treatment of blood clotting disorders
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NZ701832A (en) 2012-05-23 2016-08-26 Cellix Bio Private Ltd Compositions and methods for treatment of inflammatory bowel disease
US9227974B2 (en) 2012-05-23 2016-01-05 Cellex Bio Private Limited Compositions and methods for the treatment of respiratory disorders
US9492409B2 (en) 2012-05-23 2016-11-15 Cellix Bio Private Limited Compositions and methods for the treatment of local pain
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AU2013264820A1 (en) 2012-05-23 2014-11-27 Cellixbio Private Limited Compositions and methods for treatment of mucositis
WO2013175344A2 (en) 2012-05-23 2013-11-28 Mahesh Kandula Compositions and methods for the treatment of periodontitis and rheumatoid arthritis
US9108942B1 (en) 2014-11-05 2015-08-18 Mahesh Kandula Compositions and methods for the treatment of moderate to severe pain
WO2014020480A2 (en) 2012-08-03 2014-02-06 Mahesh Kandula Compositions and methods for the treatment migraine and neurologic diseases
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US9670153B2 (en) 2012-09-08 2017-06-06 Cellix Bio Private Limited Compositions and methods for the treatment of inflammation and lipid disorders
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Also Published As

Publication number Publication date
IL139202A0 (en) 2001-11-25
CY1108488T1 (en) 2014-04-09
GEP20032987B (en) 2003-06-25
CN1300213A (en) 2001-06-20
DE69939532D1 (en) 2008-10-23
JP3761324B2 (en) 2006-03-29
CA2325045C (en) 2005-05-03
ES2312208T3 (en) 2009-02-16
PT1077691E (en) 2008-11-04
JPH11318133A (en) 1999-11-24
UA76398C2 (en) 2006-08-15
CN1171587C (en) 2004-10-20
NZ507162A (en) 2003-11-28
EE05530B1 (en) 2012-04-16
EE200000671A (en) 2002-04-15
EG26287A (en) 2013-06-12
EA200001154A1 (en) 2001-06-25
ATE407668T1 (en) 2008-09-15
DK1077691T3 (en) 2008-10-27
EA006553B1 (en) 2006-02-24
IL139202A (en) 2014-12-31

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Effective date: 20190510