CA2321164A1 - Procede pour favoriser la proliferation et la differentiation des neurones - Google Patents

Procede pour favoriser la proliferation et la differentiation des neurones Download PDF

Info

Publication number
CA2321164A1
CA2321164A1 CA002321164A CA2321164A CA2321164A1 CA 2321164 A1 CA2321164 A1 CA 2321164A1 CA 002321164 A CA002321164 A CA 002321164A CA 2321164 A CA2321164 A CA 2321164A CA 2321164 A1 CA2321164 A1 CA 2321164A1
Authority
CA
Canada
Prior art keywords
seq
group
ala
tyr
differentiation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002321164A
Other languages
English (en)
Inventor
Kathleen E. Rodgers
Gere Dizerega
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Southern California USC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2321164A1 publication Critical patent/CA2321164A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/085—Angiotensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/14—Angiotensins: Related peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/32—Angiotensins [AT], angiotensinogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La présente invention concerne des procédés, un bouillon de culture amélioré et des kits destinés à favoriser la prolifération et/ou la différentiation des neurones par le biais de la croissance en présence de l'angiotensinogène, d'AI, d'analogues d'AI, de fragments d'AI et de leurs analogues, d'AII, d'analogues d'AII, de fragments d'AII et de leurs analogues et/ou d'agonistes des récepteurs 2 d'AT¿2? d'AI, pris séparément ou en combinaison avec d'autres facteurs de croissance et cytokines.
CA002321164A 1998-02-19 1999-02-19 Procede pour favoriser la proliferation et la differentiation des neurones Abandoned CA2321164A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7523298P 1998-02-19 1998-02-19
US60/075,232 1998-02-19
PCT/US1999/003772 WO1999042123A1 (fr) 1998-02-19 1999-02-19 Procede pour favoriser la proliferation et la differentiation des neurones

Publications (1)

Publication Number Publication Date
CA2321164A1 true CA2321164A1 (fr) 1999-08-26

Family

ID=22124390

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002321164A Abandoned CA2321164A1 (fr) 1998-02-19 1999-02-19 Procede pour favoriser la proliferation et la differentiation des neurones

Country Status (5)

Country Link
EP (1) EP1054684A1 (fr)
JP (1) JP2002503702A (fr)
AU (1) AU750029B2 (fr)
CA (1) CA2321164A1 (fr)
WO (1) WO1999042123A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6730775B1 (en) 1999-03-23 2004-05-04 University Of Southern California Methods for limiting scar and adhesion formation
US6747008B1 (en) 2000-06-19 2004-06-08 University Of Southern California Methods for treating and preventing alopecia
US20020165141A1 (en) * 2000-07-13 2002-11-07 Dizerega Gere S. Methods for promoting dendritic cell proliferation or differentiation
CN104040345A (zh) * 2011-12-23 2014-09-10 医疗研究局 血管紧张素ii受体的选择性配体
WO2014021942A1 (fr) * 2012-08-01 2014-02-06 University Of Southern California Procédés pour limiter le développement d'une neurodégénérescence
EP3935944A1 (fr) 2013-03-15 2022-01-12 University Of Southern California, USC Stevens Composés pour le traitement des maladies musculo-squelettiques
CA2902619A1 (fr) 2013-03-15 2014-09-25 University Of Southern California Methodes de traitement de la sclerose en plaques

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5015629A (en) * 1989-06-26 1991-05-14 University Of Southern California Tissue repair
US6335195B1 (en) * 1997-01-28 2002-01-01 Maret Corporation Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation

Also Published As

Publication number Publication date
JP2002503702A (ja) 2002-02-05
WO1999042123A1 (fr) 1999-08-26
AU750029B2 (en) 2002-07-11
EP1054684A1 (fr) 2000-11-29
AU2779199A (en) 1999-09-06

Similar Documents

Publication Publication Date Title
US6335195B1 (en) Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation
US6248587B1 (en) Method for promoting mesenchymal stem and lineage-specific cell proliferation
US6239109B1 (en) Method of promoting erythropoiesis
US6258778B1 (en) Methods for accelerating bone and cartilage growth and repair
US20050187163A1 (en) Methods for accelerating bone, cartilage, and connective tissue growth
WO2001030981A1 (fr) Cultures de cellules gfap?+ nestin+¿ se differenciant en neurones
WO1999026644A9 (fr) Procede favorisant la proliferation et la differentiation des cellules hematopoitiques et mesenchymateuses
AU750029B2 (en) Method of promoting neuronal cell proliferation and diffrentiation
CA2320404A1 (fr) Methode pour favoriser la proliferation de cellules souches embryonnaires
Sacerdote et al. Cloned microglial cells but not macrophages synthesize β‐endorphin in response to CRH activation
MXPA00008071A (en) Method of promoting neuronal cell proliferation and diffrentiation
WO1999039743A2 (fr) Procede de stimulation de la proliferation des cellules hepatiques
MXPA00008070A (es) Metodo para promover la proliferacion de celulaspluripotenciales embrionicas
EP1410801A1 (fr) Procédé favorisant la prolifération et la différentiation des cellules hématopoitiques

Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead