CA2321129A1 - Gene de la dystrophie corneenne de best - Google Patents

Gene de la dystrophie corneenne de best Download PDF

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Publication number
CA2321129A1
CA2321129A1 CA002321129A CA2321129A CA2321129A1 CA 2321129 A1 CA2321129 A1 CA 2321129A1 CA 002321129 A CA002321129 A CA 002321129A CA 2321129 A CA2321129 A CA 2321129A CA 2321129 A1 CA2321129 A1 CA 2321129A1
Authority
CA
Canada
Prior art keywords
seq
cg1ce
protein
dna
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002321129A
Other languages
English (en)
Inventor
Konstantin Petrukhin
C. Thomas Caskey
Michael Metzker
Claes Wadelius
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2321129A1 publication Critical patent/CA2321129A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Nouvelles séquences d'ADN humain et de souris codant le gène CG1CE qui, lorsqu'il est muté, est responsable de la dystrophie cornéenne de Best. La présente invention concerne en outre de l'ADN génomique CG1CE ainsi que de l'ADNc qui code la protéine CG1CE, la protéine CG1CE codée par les nouvelles séquences d'ADN, des procédés d'expression de la protéine CG1CE dans des systèmes de recombinaison et des méthodes diagnostiques permettant d'identifier les patients possédant des gènes CG1CE mutés.
CA002321129A 1998-02-25 1999-02-22 Gene de la dystrophie corneenne de best Abandoned CA2321129A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US7594198P 1998-02-25 1998-02-25
US11292698P 1998-12-18 1998-12-18
US60/112,926 1998-12-18
US60/075,941 1998-12-18
PCT/US1999/003790 WO1999043695A1 (fr) 1998-02-25 1999-02-22 Gene de la dystrophie corneenne de best

Publications (1)

Publication Number Publication Date
CA2321129A1 true CA2321129A1 (fr) 1999-09-02

Family

ID=26757461

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002321129A Abandoned CA2321129A1 (fr) 1998-02-25 1999-02-22 Gene de la dystrophie corneenne de best

Country Status (4)

Country Link
EP (1) EP1060184A4 (fr)
JP (1) JP2002504559A (fr)
CA (1) CA2321129A1 (fr)
WO (1) WO1999043695A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1434598A2 (fr) * 2001-10-09 2004-07-07 DeveloGen Aktiengesellschaft für entwicklungsbiologische Forschung Proteines de bestrophine et homologues de bestrophine impliquees dans la regulation de l'homeostasie de l'energie
KR101154538B1 (ko) * 2009-08-24 2012-06-13 한국과학기술연구원 소뇌에서의 ｇａｂａ 방출 조절제

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5705380A (en) * 1996-09-04 1998-01-06 Sequana Theraputics, Inc. Identification of a gene encoding TULP2, a retina specific protein
US5686598A (en) * 1996-08-22 1997-11-11 The Jackson Laboratory Genes associated with retinal dystrophies

Also Published As

Publication number Publication date
EP1060184A4 (fr) 2002-09-25
WO1999043695A1 (fr) 1999-09-02
EP1060184A1 (fr) 2000-12-20
JP2002504559A (ja) 2002-02-12

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued