CA2320088C - Analytic plate and method - Google Patents
Analytic plate and method Download PDFInfo
- Publication number
- CA2320088C CA2320088C CA2320088A CA2320088A CA2320088C CA 2320088 C CA2320088 C CA 2320088C CA 2320088 A CA2320088 A CA 2320088A CA 2320088 A CA2320088 A CA 2320088A CA 2320088 C CA2320088 C CA 2320088C
- Authority
- CA
- Canada
- Prior art keywords
- plate
- containment
- liquid
- border
- containment border
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title claims description 17
- 239000007788 liquid Substances 0.000 claims abstract description 78
- 239000003153 chemical reaction reagent Substances 0.000 claims description 34
- 239000000523 sample Substances 0.000 claims description 34
- 238000000576 coating method Methods 0.000 claims description 25
- 239000011248 coating agent Substances 0.000 claims description 24
- 229920001296 polysiloxane Polymers 0.000 claims description 24
- 239000011521 glass Substances 0.000 claims description 20
- -1 polysiloxane Polymers 0.000 claims description 20
- 239000004033 plastic Substances 0.000 claims description 13
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 claims description 12
- 239000000919 ceramic Substances 0.000 claims description 11
- 239000003960 organic solvent Substances 0.000 claims description 11
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 10
- 238000001514 detection method Methods 0.000 claims description 9
- 239000000203 mixture Substances 0.000 claims description 9
- 238000013508 migration Methods 0.000 claims description 8
- 230000005012 migration Effects 0.000 claims description 8
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 claims description 7
- 238000005299 abrasion Methods 0.000 claims description 7
- 239000008096 xylene Substances 0.000 claims description 7
- 239000012472 biological sample Substances 0.000 claims description 6
- 239000003068 molecular probe Substances 0.000 claims description 6
- 239000000975 dye Substances 0.000 claims description 5
- 150000001298 alcohols Chemical class 0.000 claims description 4
- 239000006177 biological buffer Substances 0.000 claims description 4
- 238000007431 microscopic evaluation Methods 0.000 claims description 4
- 239000002052 molecular layer Substances 0.000 claims description 4
- 125000000217 alkyl group Chemical group 0.000 claims description 3
- 238000001035 drying Methods 0.000 claims description 3
- 238000003745 diagnosis Methods 0.000 claims 3
- 239000000463 material Substances 0.000 description 14
- 239000004809 Teflon Substances 0.000 description 5
- 229920006362 Teflon® Polymers 0.000 description 5
- 238000004458 analytical method Methods 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 239000002253 acid Substances 0.000 description 4
- 239000002904 solvent Substances 0.000 description 4
- 239000000853 adhesive Substances 0.000 description 3
- 230000001070 adhesive effect Effects 0.000 description 3
- 230000004888 barrier function Effects 0.000 description 3
- 230000002401 inhibitory effect Effects 0.000 description 3
- 239000003973 paint Substances 0.000 description 3
- 239000004593 Epoxy Substances 0.000 description 2
- 150000007513 acids Chemical class 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 229920002379 silicone rubber Polymers 0.000 description 2
- 239000004945 silicone rubber Substances 0.000 description 2
- 238000012800 visualization Methods 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 239000003125 aqueous solvent Substances 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000013060 biological fluid Substances 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000001680 brushing effect Effects 0.000 description 1
- 229910010293 ceramic material Inorganic materials 0.000 description 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 239000003822 epoxy resin Substances 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 239000000834 fixative Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 238000007901 in situ hybridization Methods 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 239000003049 inorganic solvent Substances 0.000 description 1
- 229910001867 inorganic solvent Inorganic materials 0.000 description 1
- 239000011344 liquid material Substances 0.000 description 1
- 238000000386 microscopy Methods 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 230000009871 nonspecific binding Effects 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 229920000647 polyepoxide Polymers 0.000 description 1
- 239000012260 resinous material Substances 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000005201 scrubbing Methods 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0822—Slides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Clinical Laboratory Science (AREA)
- Optics & Photonics (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Microscoopes, Condenser (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/021,077 US5948685A (en) | 1998-02-10 | 1998-02-10 | Analytic plate with containment border and method of use |
| US09/021,077 | 1998-02-10 | ||
| PCT/US1999/002854 WO1999040431A1 (en) | 1998-02-10 | 1999-02-09 | Analytic plate and method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2320088A1 CA2320088A1 (en) | 1999-08-12 |
| CA2320088C true CA2320088C (en) | 2010-08-24 |
Family
ID=21802213
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2320088A Expired - Fee Related CA2320088C (en) | 1998-02-10 | 1999-02-09 | Analytic plate and method |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US5948685A (enExample) |
| EP (1) | EP1055123B1 (enExample) |
| JP (1) | JP4350305B2 (enExample) |
| CN (2) | CN1249434C (enExample) |
| AT (1) | ATE369558T1 (enExample) |
| AU (1) | AU754115B2 (enExample) |
| CA (1) | CA2320088C (enExample) |
| DE (1) | DE69936766T2 (enExample) |
| DK (1) | DK1055123T3 (enExample) |
| ES (1) | ES2292232T3 (enExample) |
| MX (1) | MXPA05003985A (enExample) |
| WO (1) | WO1999040431A1 (enExample) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6287850B1 (en) * | 1995-06-07 | 2001-09-11 | Affymetrix, Inc. | Bioarray chip reaction apparatus and its manufacture |
| EP0695941B1 (en) * | 1994-06-08 | 2002-07-31 | Affymetrix, Inc. | Method and apparatus for packaging a chip |
| US5948685A (en) * | 1998-02-10 | 1999-09-07 | Angros; Lee | Analytic plate with containment border and method of use |
| US8192994B2 (en) | 1998-02-10 | 2012-06-05 | Angros Lee H | Method of applying a biological specimen to an analytic plate |
| US6713304B2 (en) * | 1998-02-10 | 2004-03-30 | Lee H. Angros | Method of forming a containment border on an analytic plate |
| US6818451B2 (en) * | 1998-02-10 | 2004-11-16 | Lee H. Angros | Analytic plate with containment border |
| GB9925016D0 (en) * | 1999-10-23 | 1999-12-22 | Univ Sheffield | Binding surface |
| US6759011B1 (en) * | 1999-11-22 | 2004-07-06 | Ventana Medical Systems, Inc. | Stackable non-stick coverslip |
| USD473318S1 (en) | 2001-07-26 | 2003-04-15 | Biocrystal, Ltd. | Cell management device |
| GB0206930D0 (en) * | 2002-03-23 | 2002-05-08 | Univ Durham | Method and apparatus for the formation of hydrophobic surfaces |
| US7919308B2 (en) * | 2002-06-14 | 2011-04-05 | Agilent Technologies, Inc. | Form in place gaskets for assays |
| US7351379B2 (en) * | 2002-06-14 | 2008-04-01 | Agilent Technologies, Inc. | Fluid containment structure |
| US7371348B2 (en) * | 2002-06-14 | 2008-05-13 | Agilent Technologies | Multiple array format |
| US7341865B1 (en) * | 2002-10-25 | 2008-03-11 | Perlegen Sciences, Inc. | Liquid delivery devices and methods |
| US20040101439A1 (en) * | 2002-11-21 | 2004-05-27 | Fusco Adam J | Biological and chemical reaction devices and methods of manufacture |
| EP2489433A1 (en) * | 2003-09-09 | 2012-08-22 | BioGenex Laboratories | Sample processing system |
| US20050237607A1 (en) * | 2004-04-27 | 2005-10-27 | Cytyc Corporation | Microscope slide mask and method |
| US7547424B2 (en) * | 2004-09-21 | 2009-06-16 | Van Andel Research Institute | Method and apparatus for making partitioned slides |
| CA2604541C (en) * | 2005-04-15 | 2018-01-16 | Lee H. Angros | Analytic substrate coating apparatus and method |
| US20100072272A1 (en) * | 2005-10-26 | 2010-03-25 | Angros Lee H | Microscope slide coverslip and uses thereof |
| US20070092408A1 (en) * | 2005-10-26 | 2007-04-26 | Angros Lee H | Microscope coverslip and uses thereof |
| US20100073766A1 (en) * | 2005-10-26 | 2010-03-25 | Angros Lee H | Microscope slide testing and identification assembly |
| US20080056952A1 (en) | 2006-08-25 | 2008-03-06 | Angros Lee H | Analytic plates with markable portions and methods of use |
| US8049884B2 (en) * | 2006-10-06 | 2011-11-01 | Shimadzu Corporation | Spectrophotometer |
| US8013884B2 (en) * | 2008-03-09 | 2011-09-06 | Jamie P Schlinkmann | Device and method for printing information on glass surfaces |
| US11786036B2 (en) | 2008-06-27 | 2023-10-17 | Ssw Advanced Technologies, Llc | Spill containing refrigerator shelf assembly |
| US8286561B2 (en) | 2008-06-27 | 2012-10-16 | Ssw Holding Company, Inc. | Spill containing refrigerator shelf assembly |
| CA2739903C (en) | 2008-10-07 | 2016-12-06 | Ross Technology Corporation | Highly durable superhydrophobic, oleophobic and anti-icing coatings and methods and compositions for their preparation |
| WO2011056742A1 (en) * | 2009-11-04 | 2011-05-12 | Ssw Holding Company, Inc. | Cooking appliance surfaces having spill containment pattern and methods of making the same |
| JP5858441B2 (ja) | 2010-03-15 | 2016-02-10 | ロス テクノロジー コーポレーション．Ｒｏｓｓ Ｔｅｃｈｎｏｌｏｇｙ Ｃｏｒｐｏｒａｔｉｏｎ | プランジャーおよび疎水性表面を得るための方法 |
| CN103201115B (zh) | 2010-09-13 | 2016-01-20 | 普利麦罗技术公司 | 用于组织学标本载玻片和盒的彩色打印机系统 |
| US9254639B2 (en) | 2010-09-13 | 2016-02-09 | Primera Technology, Inc. | Cartridge for histological specimen slides |
| DE102011004449B4 (de) * | 2011-02-21 | 2019-01-24 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Biopsieplättchen, Einbettkassette und Diagnosevorrichtung |
| CN103476898A (zh) | 2011-02-21 | 2013-12-25 | 罗斯科技公司 | 具有低voc粘合剂体系的超疏水性和疏油性涂层 |
| DE102011085428A1 (de) | 2011-10-28 | 2013-05-02 | Schott Ag | Einlegeboden |
| EP2791255B1 (en) | 2011-12-15 | 2017-11-01 | Ross Technology Corporation | Composition and coating for superhydrophobic performance |
| AU2013281220B2 (en) | 2012-06-25 | 2017-03-16 | Ross Technology Corporation | Elastomeric coatings having hydrophobic and/or oleophobic properties |
| US9007411B2 (en) | 2012-09-19 | 2015-04-14 | Primera Technology, Inc. | Reverse transfer color printers for histological specimen slides and cassettes |
| US9360661B2 (en) | 2012-09-23 | 2016-06-07 | Alona Zilberberg | Cover-slips for an optical microscope and related methods |
| EP2969968B1 (en) | 2013-03-15 | 2022-06-22 | Lee H. Angros | Method of removing floatation liquid |
| FR3040895B1 (fr) | 2015-09-11 | 2020-01-10 | Elvesys | Substrat de support d'echantillon liquide, ensemble comportant un tel substrat et son utilisation |
| DE102017119094A1 (de) * | 2017-08-21 | 2019-02-21 | Carl Zeiss Microscopy Gmbh | Scannende Immersionsmikroskopie |
| DE102017119093A1 (de) | 2017-08-21 | 2019-02-21 | Carl Zeiss Microscopy Gmbh | Immersionsmikroskopie |
| DE102017119095B4 (de) | 2017-08-21 | 2025-02-06 | Carl Zeiss Microscopy Gmbh | Mikroskopobjektiv und Mikroskop mit einem solchen Objektiv |
| CN109444195A (zh) * | 2018-12-27 | 2019-03-08 | 中建材蚌埠玻璃工业设计研究院有限公司 | 一种纳米级钛酸钡粉末的扫描电子显微镜样品的制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3482898A (en) * | 1967-02-06 | 1969-12-09 | Francois J G Van Den Bosch | Microscope system and reservoir for chemical preparations |
| US3579540A (en) * | 1968-11-01 | 1971-05-18 | Howard G Ohlhausen | Method for protecting nonporous substrates and for rendering them water repellent |
| US3736042A (en) * | 1971-05-05 | 1973-05-29 | Clinical Sciences Inc | Microscope slide assembly |
| US3834823A (en) * | 1972-05-25 | 1974-09-10 | Gillette Co | Marking boards and erasable ink compositions therefor |
| US4447140A (en) * | 1982-09-29 | 1984-05-08 | Campbell Jeptha E | Microscope slides |
| US4481246A (en) * | 1982-11-15 | 1984-11-06 | Sybron Corporation | Microscope slide with raised marking surface |
| DE3515160A1 (de) * | 1985-04-26 | 1986-11-06 | Klaus J. Dr.med. 7800 Freiburg Bross | Verfahren zur herstellung von objekttraegern mit abgegrenzten reaktionsfeldern und die dabei erhaltenen objekttraeger |
| US4790640A (en) * | 1985-10-11 | 1988-12-13 | Nason Frederic L | Laboratory slide |
| US5485527A (en) * | 1985-11-04 | 1996-01-16 | Becton Dickinson And Company | Apparatus and method for analyses of biological specimens |
| DE3830721A1 (de) * | 1988-09-09 | 1990-03-22 | Michael Dr Menton | In labors, insbesondere in medizinischen labors, zu verwendender objekttraeger |
| JP2677734B2 (ja) * | 1992-03-25 | 1997-11-17 | 三菱鉛筆株式会社 | 水性ボールペンインキ揮発防止組成物 |
| DE19742775B4 (de) * | 1997-09-27 | 2005-03-17 | Wolfhard Zittwitz | Einschlußmittel |
| US5948685A (en) * | 1998-02-10 | 1999-09-07 | Angros; Lee | Analytic plate with containment border and method of use |
-
1998
- 1998-02-10 US US09/021,077 patent/US5948685A/en not_active Expired - Lifetime
-
1999
- 1999-02-09 CN CNB998028533A patent/CN1249434C/zh not_active Expired - Fee Related
- 1999-02-09 AU AU25968/99A patent/AU754115B2/en not_active Ceased
- 1999-02-09 DE DE69936766T patent/DE69936766T2/de not_active Expired - Lifetime
- 1999-02-09 MX MXPA05003985A patent/MXPA05003985A/es active IP Right Grant
- 1999-02-09 CN CN2006100088713A patent/CN1847829B/zh not_active Expired - Fee Related
- 1999-02-09 CA CA2320088A patent/CA2320088C/en not_active Expired - Fee Related
- 1999-02-09 ES ES99905927T patent/ES2292232T3/es not_active Expired - Lifetime
- 1999-02-09 JP JP2000530794A patent/JP4350305B2/ja not_active Expired - Fee Related
- 1999-02-09 EP EP99905927A patent/EP1055123B1/en not_active Expired - Lifetime
- 1999-02-09 WO PCT/US1999/002854 patent/WO1999040431A1/en not_active Ceased
- 1999-02-09 AT AT99905927T patent/ATE369558T1/de active
- 1999-02-09 DK DK99905927T patent/DK1055123T3/da active
- 1999-08-06 US US09/370,512 patent/US6372507B1/en not_active Expired - Lifetime
- 1999-08-12 US US09/373,468 patent/US6555384B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69936766D1 (de) | 2007-09-20 |
| ATE369558T1 (de) | 2007-08-15 |
| JP4350305B2 (ja) | 2009-10-21 |
| JP2002502976A (ja) | 2002-01-29 |
| CN1847829A (zh) | 2006-10-18 |
| WO1999040431A1 (en) | 1999-08-12 |
| EP1055123A1 (en) | 2000-11-29 |
| HK1036104A1 (en) | 2001-12-21 |
| US6372507B1 (en) | 2002-04-16 |
| CA2320088A1 (en) | 1999-08-12 |
| DK1055123T3 (da) | 2007-12-27 |
| CN1249434C (zh) | 2006-04-05 |
| US5948685A (en) | 1999-09-07 |
| MXPA05003985A (es) | 2005-09-08 |
| AU2596899A (en) | 1999-08-23 |
| CN1290348A (zh) | 2001-04-04 |
| ES2292232T3 (es) | 2008-03-01 |
| DE69936766T2 (de) | 2008-04-30 |
| EP1055123A4 (en) | 2004-12-01 |
| EP1055123B1 (en) | 2007-08-08 |
| US6555384B1 (en) | 2003-04-29 |
| CN1847829B (zh) | 2010-08-18 |
| AU754115B2 (en) | 2002-11-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20180209 |