CA2317050C - Use of neonicodinoids on transgenic plants - Google Patents

Use of neonicodinoids on transgenic plants Download PDF

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CA2317050C
CA2317050C CA002317050A CA2317050A CA2317050C CA 2317050 C CA2317050 C CA 2317050C CA 002317050 A CA002317050 A CA 002317050A CA 2317050 A CA2317050 A CA 2317050A CA 2317050 C CA2317050 C CA 2317050C
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fungal pathogens
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Bruce Lee
Marius Sutter
Hubert Buholzer
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Syngenta Participations AG
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N51/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds having the sequences of atoms O—N—S, X—O—S, N—N—S, O—N—N or O-halogen, regardless of the number of bonds each atom has and with no atom of these sequences forming part of a heterocyclic ring

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Abstract

There is now described a method of controlling pests with nitroimino- or nitroguanidino-compounds; more specifically a method of controlling pests in and on transgenic crops of useful plants, such as, for example, in crops of maize, cereals, soya beans, tomatoes, cotton, potatoes, rice and mustard, with a nitroimino- or nitroguanidino-compound, especially with thiamethoxam, characterized in that a pestical composition comprising a nitroimino- or nitroguanidino- compound in free form or in agrochemically useful salt form and at least one auxiliary is applied to the pests or their environment, in particular to the crop plant itself.

Description

USE OF NEONICODINOIDS ON TRANSGENIC PLANTS

The present invention relates to a method of oontrolling pests with a nitroimino- or nitroguanidino-compound, especially thiamethoxam; more specifically to a novel method of controlling pests in and on transgenic crops of useful plants with a nitroimino- or nitroguanidino-compound.

Certain pest control methods are proposed in the iitereture. However, these mettiods are not fully satisfactory in the field of pest control, which is why there is a demand for providing further methods for controlling and combating pests, in particular insects and repre-sentatives of the order Acarina, or for protecting plants, especially crop plants. This object is achieved according to the invention by providing the present method.

The present invention therefore relates to a method of controlling pests in crops of transgenic useful plants, such as, for example, in crops of maize, cereals, soya beans, tomatoes, cotton, potatoes, rice and mustard, characterized in that a pesticidal composition comprising a nitroimino- or nitroguanidino-compound, especially thiamethoxam, imidacloprid, Ti-435 or thiacioprid in tree form or in agrochemically useful salt form and at least one auxiliary is applied to the pests or their environment, in particular to the crop plant itsetf; to the use of the composition In question and to propagation material of transgenic plants which has been treated with it.

Surprisingly, it has now emerged that the use of a nitroimino- or nitroguanidino-compound compound for controlling pests on transgenic' useful plants which contain -for instance -one or more genes expressing a pesticidally, particularly insecticidally, acaricidally, nematocidally or fugicidally active ingredient, or which are tolerant against herbicides or resistent against the attack of fungi, has a synergistic effect. It is highly surprising that the use of a nitroimino- or nitroguanidino-compound in combination with a transgenic plant exceeds the additive effect, to be expected in principle, on the pests to be controlled and thus extends the range of action of the nitroimino- or nitroguanidino-compound and of the active principle expressed by the transgenic plant in particular in two respects:

In particular, it has been found, surprisingly, that wjthin the scope of invention the pesticidal activity of a nitroimino- or nitroguanidino-compound in combination with the effect expressed by the transgenic useful plant, is not only additive in comparison with the pesticidal activities of the nitroimino- or nitroguanidino-compound alone and of the transgenic crop plant alone, as can generally be expected, but that a synergistic effect is present. The term "synergistic", however, Is in no way to be understood in this connecaon as being restricted to the pesticidal activity, but the term also refers to other advantageous properties of the method according to the invention compared with the nitroimino- or nitroguanidino-compound and the transgenic useful plant alone. Examples of such advantageous properties which may be mentioned are: extension of the pesticidal spectrum of action to other pests, for example to resistant strains; reduction in the application rate of the nitroimino- or nitroguanidino-compound, or sufficient control of the pests with the aid of the compositions according to the invention even at an application rate of the nitroimino- or nitroguanidino-compound alone and the transgenic useful plant alone are entirely ineffective; enhanced crop safety; improved quality of produce such as higher content of nutrient or oil, better fiber quality, enhanced shelf life, reduced content of toxic products such as mycotoxins, reduced content of residues or unfavorable constituents of any kind or better digestability; improved tolerance to unfavorable temperatures, draughts or salt content of water; enhanced assimilation rates such as riutrient uptake, water uptake and photosynthesis; favorable crop properties such as altered leaf aerea, reduced vegetative growth, increased yields, favorable seed shape/seed thickness or germination properties, altered colonialisation by saprophytes or epiphytes, reduction of senescense, improved phytoalexin production, improved of accelerated ripening, flower set increase, reduced boll fall and shattering, better attraction to beneficials and predators, increased pollination, reduced attraction to birds; or other advantages known to those skilled in the art.

Nitroimino- and nitroguanidino-cpmpounds, such as thiamethoxam (5-(2-Chlorthiazol-5-ylmethyl)-3-methyl-4-nitroimino-perhydro-1,3,5-oxadiazin), are known from EP-A-O'580'553.
Within the scope of invention thiamethoxam is preferred.

Also preferred within the scope of invention is imidacloprid of the formula CI

N N~N, H , known from The Pesticide Manual, 10"'Ed. (1991), The N~, British Crop Protection Council, London, page 591;
also also preferred is Thiacloprid of the formula N~ N S , known from I I
N, CN
EP-A-235'725;

CI

S
also preferred is the compound of the formula N H CH3 , known as N N, Y H

N~

Ti-435 (Clothiamidin) from EP-A-376'279 The agrochemically compatible salts of the nitroimino- or nitroguanidino-compounds are, for example, acid addition salts of inorganic and organic acids, in particular of hydrochloric acid, hydrobromic acid, sulfuric acid, nitric acid, perchioric acid, phosphoric acid, formic acid, acetic acid, trifluoroacetic acid, oxalic acid, malonic acid, toluenesulfonic acid or benzoic acid. Preferred within the scope of the present invention is a composition known per se which comprises, as active ingredient, thiamethoxam and imidacloprid, each in the free form, especially thiamethoxam.

The transgenic plants used according to the invention are plants, or propagation material thereof, which are transformed by means of recombinant DNA technology in such a way that they are - for instance - capable of synthesizing selectively acting toxins as are known, for example, from toxin-producinginvertebrates, especially of the phylum Arthropoda, as can be obtained from Bacillus thuringiensis strains; or as are known from plants, such as lectins;
or in the alternative capable of expressing a herbicidal or fungicidal resistance. Examples of such toxins, or transgenic plants which are capable of synthesizing such toxins, have been disclosed, for example, in EP-A-O 374 753, WO 93/07278, WO 95/34656, EP-A-0 and EP-A-451 878.

The methods for generating such transgenic plants are widely known to those skilled in the art and described, for example, in the publications mentioned above.

WO 99/35913 PCT/EP"/00183 The toxins which can be expressed by such transgenic plants indude, for example, toxins, such as proteins which have insecticidal properties and which are expressed by transgenic plants, for example Bacillus cereus proteins or Bacillus popliae proteins; or Bacillus thuringiensis endotoxins (B.t.), such as CrylA(a), CrylA(b), CrylA(c), CryllA, CryltlA, CryIIlB2 orCytA; VIP1; VIP2; VIP3; or insecticidal proteins of bacteria colonising nematodes like Photorhabdus spp or Xenorhabdus spp such as Photorhabdus luminescens, Xenorhabdus nematophilus etc.; proteinas6 inhibitors, such as trypsin inhibitors, serine protease inhibitors, patatin, cystatin, papain inhibitors; ribosome-inactivvating proteins (RIP), such as ricin, maize RIP, abrin, luffin, saporin or bryodin; plant lectins such as pea lectins, barley lectins or snowdrop lectins; or agglutinins; toxins produced by animals, such as scorpion toxins, spider venoms, wasp venoms and other insect-specific neurotoxins;
steroid metabolism enzymes, such as 3-hydroxysteroid oxidase, ecdysteroid UDP-glycosyl transferase, cholesterol oxidases, ecdysone inhibitors, HMG-COAreductase, ion channel blockers such as sodium and calcium, juvenile hormone esterase, diuretic hormone receptors, stilbene synthase, bibenzyl synthase, chitinases and glucanases.

Examples of known transgenic plants which comprise one or more genes which encode insecticidal resistance and express one or more toxins are the foilowing:
KnockOut (maize), YieldGard (maize); NuCOTN 33B (cotton), Bollgard(t (cotton), NewLeaf (potatoes), NatureGard and Protecta .

The following tables comprise further examples of targets and principles and crop phenotypes of transgenic crops which show tolerance against pests mainly insects, mites, nematodes, virus, bacteria and diseases or are tolerant to specific herbicides or classes of herbicides.

Table Al: Crop: Maize Effected target or expressed principle(s) Crop phenotype / Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Effected target or expressed principle(s) Crop phenotype / Toierance to Hydroxyphenyipyruvate dioxygenase isoxazofes such as tsoxafiutol or (HPPD) isoxachiortoi, Triones such as mesotrione or suicotrione Phosphinothricin acetyl transferase Phosphinothftn 0-Methyl transferase altered lignin levels Giutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) tnhibitors of IMP and AMP synthesis Adenylosuccinate Synthase inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and loxinyl 5-Enoipyruvyi-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or suffosate Protoporphyrinogen oxidase (PROTOX) Diphenyiethers, cyclic imides, phenyipyrazoies, pyridin derivatives, phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 Xenobiotics and herbicides such as Sulfonyiureas Dimboa biosynthesis (Bxl gene) Helminthosporium turcicum, Rhopalosiphum maydis, Diplodia maydis, Ostrinia nubilalis, lepidoptera sp.
CMIII (small basic maize seed peptide plant pathogenes eg. fusarium, aitemaria, scterotina Com- SAFP (zeamatin) plant pathogenes eg. fusarium, altemaria, sclerotina, rhizoctonia, chaetomium,phycomyces Hml gene Cochliobulus Chitinases plant pathogenes Glucanases plant pathogenes Coat proteins viruses such as maize dwarf mosaic Effected target or expressed principie(s) Crop phenotype / Toleran+re to virus, maize chiorotic dwarf virus Bacillus thuringiensis toxins, VIP 3, iepidoptera, coieoptera, diptera, Bacillus cereus toxins, Photorabdus and nematodes, eg. ostrinia nubilaiis, Xenorhabdus toxins heiiothis zea, armyworms eg.
spodoptera frugiperda, com rootworms, sesamia sp., black cuiworm, asian com borer,weeviis 3- Hydroxysteroid oxidase iepidoptera, coleoptera, diptera, nematodes, eg. ostrinia nubilalis, heliothis zea, armyworms eg.
spodoptera frugiperda, com rootworms, sesamia sp., black cutworm, asian com borer, weevils Peroxidase lepidoptera, coieoptera, diptera, nematodes, eg. ostrinia nubilatis, heliothis zea, armyworms eg.
spodoptera frugiperda, com rootworms, sesamia sp., black cutworm, asian com borer, weevils Aminopeptidase inhibitors eg. Leucine lepidoptera, coieoptera, diptera, aminopeptidase inhibitor (LAPI) nematodes, eg. ostrinia nubilalis, heliothis zea, armyworms eg.
spodoptera frugiperda, com rootworms, sesamia sp., black cutworm, asian com borer, weevils Limonene synthase com rootworms Lectines lepidoptera, coleoptera, diptera, nematodes, eg. ostrinia nubilalis, heliothis zea, armyworms eg.
spodoptera frugiperda, com rootworms, sesamia sp., biack cutworm, asian com borer, weevils WO 99/35913 pCT/EP"/00183 Effected target or expressed principle(s) Crop phenotype / Tolerance to Protease Inhibitors eg. cystatin, patatin, weevils, com rootwomn virgiferin, CPTI
ribosome inactivating protein lepidoptera, coleoptera, diptera, nematodes, eg. ostrinia nubilalis, hellothis zea, armywomns eg.
spodop=.era frugiperda, com rootworms, sesamia sp., black cutworm, asian com borer, weevils maize 5C9 polypeptide lepidoptera, coleoptera, diptera, nematodes, eg. ostrinia nubilalis, heliothis zea, armyworms eg.
spodoptera frugiperda, com rootworms, sesamia sp., black cutworm, asian com borer, weevils HMG-CoA reductase lepidoptera, coieoptera, diptera, nematodes, eg. ostrinia nubilalis, heliothis zea, armyworms eg.
spodoptera frugiperda, com rootworms, sesamia sp., black cutworm, asian com borer, weevils Table A2: Crop Wheat Effected target or expressed principle(s) Crop phenotype / Toierance to Acetolactate synthase (ALS) Sulfonylureas, lmidazoiinones, Triazoiopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxafiutol or (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione -g-Effected target or expressed principie(s) Crop phenotype / Tolerance to Phosphinothricin acetyl transferase Phosphinothrkin 0-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase inhibitors of adenytosuccinate synthesis Anthranitate Synttt.:se inhibitors of tryptophan synthesis and catabolism Nitritase 3,5-dihaio-4-hydroxy-benzonitriies such as Bromoxynil and loxinyl 5-Enoipyruvyi-3phosphoshikimate Glyphosate or suifosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides, phenyipyrazoies, pyridin derivatives, phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 Xenobiotics and herbicides such as Sulfonyiureas Antifungal polypeptide AIyAFP plant pathogenes eg septoria and fusarioum glucose oxidase plant pathogenes eg. fusarium, septoria pyrroinitrin synthesis genes plant pathogenes eg. fusarium, septoria serine/threonine kinases plant pathogenes eg. fusarium, septoria and other diseases Hypersensitive response eliciting plant pathogenes eg. fusarium, septoria polypeptide and other diseases Systemic acquires resistance (SAR) viral, bacteriai, fungal, nematodal genes pathogens Chitinases plant pathogenes Glucanases plant pathogenes double stranded ribonuclease viruses such as BYDV and MSMV
Coat proteins viruses such as BYDV and MSMV
Bacillus thuringiensis toxins, VIP 3, iepidoptera, coleoptera, diptera, WO 99/35913 pCT~~~183 Effected target or expressed principle(s) Crop phenotype / Tolerance to Bacillus cereus toxins, Photorabdus and nematodes, Xenorhabdus toxins 3- Hydroxysteroid oxidase lepidoptera, coieoptera, diptera, nematodes, Peroxidase lepidoptera, coieoptera, diptera, nematodes, Aminopeptidase inhibitors eg. Leucine lepidoptera, coleoptera, diptera, aminopeptidase inhibitor nematodes, Lectines lepidoptera, coleoptera, diptera, nematodes, aphids Protease Inhibitors eg. cystatin, patatin, lepidoptera, coleoptera, diptera, virgiferin, CPTI nematodes, aphids ribosome inactivating protein lepidoptera, coleoptera, diptera, nematodes, aphids HMG-CoA reductase lepidoptera, coleoptera, diptera, nematodes, eg. ostrinia nubilalis, heliothis zea, armyworms eg.
spodoptera frugiperda, com rootworms, sesamia sp., black cutworm, asian com borer, weevils Table A3: Crop Barley Effected target or expressed principle(s) Crop phenotype I Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazoiinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate dioxygenase isoxazoles such as Isoxaflutol or (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Effected target or expressed principle(s) Crop phenotype / Tolerance to Phosphinothricin acetyl transferase Phosphinothricin O-Methyl transfemse attered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis ATdhranilsa-a Synthase lnhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sutfosate Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides, phenyfpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SUI Xenobiotics and herbicides such as Sulfonylureas Antifungal polypeptide AIyAFP plant pathogenes eg septoria and fusarioum glucose oxidase plant pathogenes eg. fusarium, septoria pyrroinitrin synthesis genes plant pathogenes eg. fusarium, septoria serine/threonine kinases plant pathogenes eg. fusarium, septoria and other diseases Hypersensitive response eliciting plant pathogenes eg. fusarium, septoria polypeptide and other diseases Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal genes pathogens Chitinases plant pathogenes Glucanases plant pathogenes double stranded ribonuclease viruses such as BYDV and MSMV
Coat proteins viruses such as BYDV and MSMV
Bacillus thuringiensis toxins, VIP 3, lepidoptera, coieoptera, diptera, WO 99/35913 PCT/EP"/00183 Effected target or expressed principle(s) Crop phenotype / Tolerance to Bacillus cereus toxins, Photorabdus and nematodes, Xenorhabdus toxins 3- Hydroxysteroid oxidase lepidoptera, coleoptera, diptera, nematodes, Peroxidase lepidoptera, coleoptera, diptera, nematodes, Aminopeptidase inhibitors eg. Leucine lepidoptera, coleoptera, diptera, aminopeptidase inhibitor nematodes, Lectines lepidoptera, coleoptera, diptera, nematodes, aphids Protease Inhibitors eg. cystatin, patatin, lepidoptera, coleoptera, diptera, virgiferin, CPTI nematodes, aphids ribosome inactivating protein iepidoptera, coleoptera, diptera, nematodes, aphids HMG-CoA reductase lepidoptera, co{eoptera, diptera, nematodes, aphids Table A4: Crop Rice Effected target or expressed principle(s) Crop phenotype / Tolerance to Acetolactate synthase (ALS) Sutfonylureas, lmidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenyfpyruvate dioxygenase Isoxazoles such as Isoxaflutol or (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin 0-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis WO 99/35913 PCT/EP"/00183 Effected target or expressed principle(s) Crop phenotype / Tolerance to Adenyiosuccinate Synthase inhlbitors of adenyiosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitdlase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and loxinyl 5-Enolpyruvy!-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase (PROTOX) Diphenyfethers, cyclic imides, phenyipyn3zoles, pyridin derivatives, phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SUI Xenobiotics and herbicides such as Sulfonylureas Antifungal polypeptide AIyAFP plant pathogenes glucose oxidase plant pathogenes pyrroinitrin synthesis genes plant pathogenes serine/threonine kinases plant pathogenes Phenylaianine ammonia lyase (PAL) plant pathogenes eg bacterial leaf blight and rice blast, inducible phytoalexins plant pathogenes eg bacterial leaf blight and rice blast B-1,3-glucanase antisense plant pathogenes eg bacterial leaf blight and rice blast receptor kinase plant pathogenes eg bacterial leaf blight and rice blast Hypersensitive response eliciting plant pathogenes polypeptide Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal genes pathogens Chitinases plant pathogenes eg bacterial leaf blight and rice blast Glucanases plant pathogenes Effected target or expressed principle(s) Crop phenotype / Tolemnce to double stranded ribonuclease viruses such as BYDV and MSMV
Coat proteins vinlses such as BYDV and MSMV
Bacillus thuringiensis toxins, VIP 3, lepidoptera eg. stemborer, coleoptera eg Bacillus cereus toxins, Photorabdus and rice water weevil, diptera, rice hoppers Xenorhabdus toxins eg brown rice hopper 3- Hydroxyrteroid oxidase lepidoptera eg. stemborer, coleoptera eg rice water weevil, diptera, rice hoppers eg brown rice hopper Peroxidase iepidoptera eg. stemborer, coleoptera eg rice water weevil, diptera, rice hoppers eg brown rice hopper Aminopeptidase inhibitors eg. Leucine lepidoptera eg. stemborer; coleoptera eg aminopeptidase inhibitor rice water weevil, diptera, rice hoppers eg brown rice hopper Lectines lepidoptera eg. stemborer, coieoptera eg rice water weevil, diptera, rice hoppers eg brown rice hopper Protease Inhibitors, iepidoptera eg. stemborer, coleoptera eg rice water weevil, diptera, rice hoppers eg brown rice hopper ribosome inactivating protein lepidoptera eg. stemborer, coleoptera eg rice water weevil, diptera, rice hoppers eg brown rice hopper HMG-CoA reductase lepidoptera eg. stemborer, coleoptera eg rice water weevil, diptera, rice hoppers eg brown rice hopper Table A5: Crop Soya Effected target or expressed principle(s) Crop phenotype / Toierance to Effected target or expressed principie(s) Crop phenotype / Toieranoe to Acetolactate synthase (ALS) Sulfonyiureas, Imidazoiinones, Triazotopyrimidines, Pyrimidyioxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyaikanecarboxyiic acids, cyclohexanediones Hydroxyphenylpyruvate dioxygenase Isoxazoles such as tsoxatiutol or (HPPD) Isoxachlortoi, Triones such as mesotrione or suicotrione Phosphinothricin acetyl transfen3se Phosphinothricin 0-Methyl transf erase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihato-4-hydroxy-benzonitriles such as Bromoxynil and loxinyl 5-Enoipyruvyi-3phosphoshikimate Giyphosate or sulfosate Synthase (EPSPS) Gtyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides, phenytpyrazoies, pyridin derivatives, phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as setection Suifonyiureas Antifungat polypeptide AIyAFP bacterial and fungal pathogens such as fusarium, scterotinia, stemrot oxalate oxidase bacterial and fungal pathogens such as fusarium, scierotinia, stemrot glucose oxidase bacterial and fungal pathogens such as fusarium, scierotinia, stemrot pyrrolnitrin synthesis genes bacterial and fungal pathogens such as WO 99/35913 PCT/I:P99/00183 Effected target or expressed principte(s) Crop phenotype / Toleranos to fusarium, scierotinia, stemrot serine/threonine kinases bacterial and fungal pathogens such as fusarium, sderotinia, stemrot Phenytaianine ammonia lyase (PAL) bacterial and fungal pathogens such as fusarium, sderotinia, stemrot phytoaiexins plant pathogenes eg bacterisl leaf blight and rice blast B-1,3-glucanase antisense plant pathogenes eg bacterial leaf blight and rice blast receptor kinase bacterial and fungal pathogens such as fusarium, sclerotinia, stemrot Hypersensitive response eliciting plant pathogenes poiypeptide Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal genes pathogens Chitinases bacterial and fungal pathogens such as fusarium, sderotinia, stemrot Glucanases bacterial and fungal pathogens such as fusarium, scierotinia, stemrot double stranded ribonuclease viruses such as BPMV and SbMV
Coat proteins viruses such as BYDV and MSMV
Bacilius thuringiensis toxins, VIP 3, lepidoptera, coleoptera, aphids Bacillus cereus toxins, Photorabdus and Xenorhabdus toxins 3- Hydroxysteroid oxidase lepidoptera, coleoptera, aphids Peroxidase lepidoptera, coleoptera, aphids Aminopeptidase inhibitors eg. Leucine lepidoptera, coleoptera, aphids aminopeptidase inhibitor Lectines lepidoptera, coleoptera, aphids Protease Inhibitors eg virgiferin lepidoptera, coleoptera, aphids Effected target or expressed principle(s) Crop phenotype / Tolerance to ribosome inactivating protein lepidoptera, coleoptera, aphids HMG-CoA reductase lepidoptera, coleoptera, aphids Bamase nematodes eg root knot nematodes and cyst nematodes Cyst nematode hatching stimulus cyst nematodes Antifeeding principles nematodes eg root knot nematodes and cyst nematodes Table A6: Crop Potatoes Effected target or expressed principle(s) Crop phenotype ! Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate dioxygenase isoxazoles such as isoxafiutol or (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin 0-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Effected target or expressed principie(s) Crop phenotype / Toierance to Giypnosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides, phenylpyrazoles, pyridin derrvatives, phenopyiate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as selection Sultonytureas Polyphenol oxidase or Polyphenol blackspot bnjise oxidase antisense Metallothionein bacterial and fungal pathogens such as phytophtora Ribonuciease Phytophtora, Verticiliium, Rhizoctonia Antifungat polypeptide AIyAFP bacterial and fungal pathogens such as phytophtora oxalate oxidase bacterial and fungal pathogens such as Phytophtora, Verticillium, Rhizoctonia glucose oxidase bacterial and fungal pathogens such as Phytophtora, Verticillium, Rhizoctonia pyrrotnitrin synthesis genes bacterial and fungal pathogens such as Phytophtora, Verticiilium, Rhizoctonia serine/threonine kinases bacterial and fungal pathogens such as Phytophtora, Verticillium, Rhizoctonia Cecropin B bacteria such as corynebacterium sepedonicum, Erwinia carotovora Phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens such as Phytophtora, Verticillium, Rhizoctonia phytoalexins bacterial and fungal pathogens such as Phytophtora, Verticillium, Rhizoctonia B-1,3-gtucanase antisense bacterial and fungal pathogens such as Phytophtora, Verticillium, Rhizoctonia receptor kinase bacterial and fungal pathogens such as Phytophtora, Verticillium, Rhizoctonia Effected target or expressed principie(s) Crop phenotype I Toierance to Hypersensitive response eliciting bacterial and fungai pathogens such as polypeptide Phytophtora, Veraciliium, Rhizoctonia Systemic acquires resistance (SAR) virai, bacterial, fungai, nematodai genes pathogens Chitinases bacterial and fungal pathogens such as Phytophtora, Verticiiiium, Rhizocionia Bamase bacterial and fungal pathogens such as Phytophtora, Verticiiiium, Rhizoctonia Disease resistance response gene 49 bacteriai and fungal pathogens such as Phytophtora, Verticillium, Rhizoctonia trans aldolase antisense blackspots Glucanases bacterial and fungal pathogens such as Phytophtora, Verticillium, Rhizoctonia double stranded ribonuciease viruses such as PLRV, PVY and TRV
Coat proteins vinises such as PLRV, PVY and TRV
17kDa or 60 kDa protein viruses such as PLRV, PVY and TRV
Nuclear inclusion proteins eg. a or b viruses such as PLRV, PVY and TRV
Pseudoubiquitin viruses such as PLRV, PVY and TRV
Replicase viruses such as PLRV, PVY and TRV
Bacillus thuringiensis toxins, VIP 3, coieoptera eg colorado potato beetle, Bacillus cereus toxins, Photorabdus and aphids Xenorhabdus toxins 3- Hydroxysteroid oxidase coleoptera eg colorado potato beetle, aphids Peroxidase coleoptera eg coiorado potato beetle, aphids Aminopeptidase inhibitors eg. Leucine coleoptera eg colorado potato beetle, aminopeptidase inhibitor aphids stilbene synthase coleoptera eg colorado potato beetle, aphids WO 99/35913 PCT/EP"/00183 Effected target or expressed principie(s) Crop phenotype / Toierance to Lectines coleoptera eg colorado potato beetle, aphids Protease Inhibitors eg cystatin, patatin coleoptera eg colorado potato beetle, aphids rbosome inactivating protein coleoptera eg coiorado potato beetle, aphids HMG-CoA reductase coleoptera eg colorado potato beetle, aphids Cyst nematode hatching stimulus cyst nematodes Bamase nematodes eg root knot nematodes and cyst nematodes Antifeeding principles nematodes eg root knot nematodes and cyst nematodes Table A7:.Crop Tomatoes Effected target or expressed principle(s) Crop phenotype / Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or (HPPD) lsoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin 0-Methyl transf erase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and Effected target or expressed principle(s) Crop phenotype / Tolerance to catabolism Nitrilase 3,5-dihaio-4-hydroxy-benzonitriies such as Bromoxynii and loxinyl 5-Enoipyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosete Protoporphyrinogen oxidase (PROTOX) Diphenyiethers, cyclic imides, phenyipyrazoies, pyridin derivatives, phenopyiate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as selection Sulfonyiureas Polyphenol oxidase or Polyphenol blackspot bruise oxidase antisense Metallothionein bacterial and fungal pathogens such as phytophtora Ribonuclease Phytophtora, Verticillium, Rhizoctonia Antifungal polypeptide AiyAFP bacteriai and fungal pathogens such as bacteriai speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc.

oxalate oxidase bacterial and fungal pathogens such as bacteriai speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc.
glucose oxidase bacterial and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc.
pyrroinitrin synthesis genes bacteriai and fungal pathogens such as bacteriai speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould Effected target or expressed principle(s) Crop phenotype / Tolerance to etc.
serine/threonine kinases bacterial and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery miidew, crown rot, leaf mould etc.
Cecropin B bacterial and fungai pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc.
Phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc.
Cf genes eg. Cf 9 Cf5 Cf4 Cf2 leaf mould Osmotin aitemaria solani Alpha Hordothionin bacteria Systemin bacterial and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc.
Poiygalacturonase inhibitors bacterial and fungal pathogens such as bacteriai speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc.
Prf regulatory gene bacterial and fungal pathogens such as bacteriai speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc.
12 Fusarium resistance locus fusarium phytoalexins bacterial and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould Effected target or expressed principle(s) Crop phenotype / Tolerance to etc.
B-1,3-giucanase antisense bacteriai and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc.
receptor kinase bacterial and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc.
Hypersensitive response eliciting bacterial and fungal pathogens such as polypeptide bacteriai speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc.
Systemic acquires resistance (SAR) virai, bacterial, fungal, nematodal geries pathogens Chitinases bacterial and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc.
Bamase bacteriai and fungal pathogens such as bacterial speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc.
Glucanases bacterial and fungal pathogens such as bacteriai speck, fusarium, soft rot, powdery mildew, crown rot, leaf mould etc.
double stranded ribonuciease viruses such as PLRV, PVY and ToMoV
Coat proteins viruses such as PLRV, PVY and ToMoV
17kDa or 60 kDa protein viruses such as PLRV, PVY and ToMoV
Nuclear inclusion proteins eg. a or b or viruses such as PLRV, PVY and ToMoV

WO 99/35913 PCT~~~193 Effected target or expressed principle(s) Crop phenotype / Tolerancx3 to Nucleoprotein TRV
Pseudoubiquitin vinises such as PLRV, PVY and ToMoV
Replicase viruses such as PLRV, PVY and ToMoV
Bacillus thuringiensis toxins, VIP 3, lepidoptera eg heliothis, whiteflies Bacillus cereus toxins, Photorabdus and aphids Xenorhabdus toxins 3- Hydroxysteroid oxidase lepidoptera eg heliothis, whitefties aphids Peroxidase lepidoptera eg heliothis, whiteflies aphids Aminopeptidase inhibitors eg. Leucine lepidoptera eg heliothis, whiteflies aminopeptidase inhibitor aphids Lectines lepidoptera eg heliothis, whiteflies aphids Protease Inhibitors eg cystatin, patatin lepidoptera eg heliothis, whiteflies aphids ribosome inactivating protein lepidoptera eg heliothis, whiteflies aphids stilbene synthase lepidoptera eg heliothis, whitefties aphids HMG-CoA reductase lepidoptera eg heliothis, whiteflies aphids Cyst nematode hatching stimulus cyst nematodes Bamase nematodes eg root knot nematodes and cyst nematodes Antifeeding principles nematodes eg root knot nematodes and cyst nematodes Table AB: Crop Peppers Effected target or expressed principle(s) Crop phenotype / Tolerance to Acetolactate synthase (ALS) Sulfonylureas, lmidazolinones, Effected target or expressed principie(s) Crop phenotype / Tolerance to Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin 0-Methyl transferase altered iignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitrifes such as Bromoxynil and loxinyl 5-Enotpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides, phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as seiection Sulfonylureas Polyphenol oxidase or Polyphenol bacterial and fungal pathogens oxidase antisense Metallothionein bacterial and fungal pathogens Ribonuclease bacterial and fungal pathogens Antifungal polypeptide AIyAFP bacterial and fungal pathogens oxalate oxidase bacterial and fungal pathogens glucose oxidase bacterial and fungal pathogens pyrroinitrin synthesis genes bacterial and fungal pathogens Effected target or expressed principle(s) Crop phenotype / Tolerance to serine/threonine kinases bacterial and fungal pathogens Cecropin B bacterial and fungal pathogens rot, leaf mould etc.

Phenylaianine ammonia lyase (PAL) bacteriai and fungal pathogens Cf genes eg. Cf 9 Ct5 C4 Cf2 bacteriai and fungai pathogens Osmotin bacterial and fungal pathogens Alpha Hordothionin bacterial and fungal pathogens Systemin bacterial and fungal pathogens Polygalacturonase inhibitors bacterial and fungal pathogens Prf regulatory gene bacterial and fungal pathogens 12 Fusarium resistance locus fusarium phytoalexins bacterial and fungal pathogens B-1,3-glucanase antisense bacterial and fungal pathogens receptor kinase bacterial and fungal pathogens Hypersensitive response eliciting bacterial and fungal pathogens polypeptide Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal genes pathogens Chitinases bacterial and fungal pathogens Bamase bacterial and fungal pathogens Glucanases bacterial and fungal pathogens double stranded ribonuclease viruses such as CMV, TEV
Coat proteins viruses such as CMV, TEV
17kDa or 60 kDa protein viruses such as CMV, TEV
Nuclear inclusion proteins eg. a or b or viruses such as CMV, TEV
Nucleoprotein Pseudoubiquitin viruses such as CMV, TEV
Replicase viruses such as CMV, TEV
Bacillus thuringiensis toxins, VIP 3, lepidoptera, whitefiies aphids Bacillus cereus toxins, Photorabdus and Xenorhabdus toxins Effected target or expressed principie(s) Crop phenotype / Tolerance to 3- Hydroxysteroid oxidase iepidoptera, whiteflies aphids Peroxidase lepidoptera, whiteflies aphids Aminopeptidase inhibitors eg. Leucine lepidoptera, whiteflies aphids aminopeptidase inhibitor Lectines lepidoptera, whiteflies aphids Protease Inhibitors eg cystatin, patatin lepldoptera, whitefiies aphids ribosome inactivating protein lepidoptera, whiteflies aphids stilbene synthase lepidoptera, whitefiies aphids HMG-CoA reductase lepidoptera, whitefiies aphids Cyst nematode hatching stimulus cyst nematodes Bamase nematodes eg root knot nematodes and cyst nematodes Antifeeding principies nematodes eg root knot nematodes and cyst nematodes Table A9: Crop Grapes Effected target or expressed principie(s) Crop phenotype / Tolerance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate dioxygenase Isoxazoles such as lsoxaflutol or (HPPD) Isoxachiortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin 0-Methyl transterase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenyiosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and Effected target or expressed principle(s) Crop phenotype / Toleranoe to catabolism Nitrilase 3,5-dihaio-4-hydroxy-benzonitriies such as Bromoxynil and loxinyi 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Giyphosate oxidoreduC.ar.e a!yphosate or sulfosate Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides;
phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as selection Sulfonylureas Polyphenol oxidase or Polyphenol bacterial and fungal pathogens like oxidase antisense Botrytis and powdery mildew Metallothionein bacterial and fungal pathogens like Botrytis and powdery mildew Ribonuclease bacterial and fungal pathogens like Botrytis and powdery mildew Antifungal polypeptide AIyAFP bacterial and fungal pathogens like Botrytis and powdery mildew oxalate oxidase bacterial and fungal pathogens like Botrytis and powdery mildew glucose oxidase bacterial and fungal pathogens like Botrytis and powdery mildew pyrrolnitrin synthesis genes bacterial and fungal pathogens like Botrytis and powdery mildew serine/threonine kinases bacterial and fungal pathogens like Botrytis and powdery mildew Cecropin B bacterial and fungal pathogens like Botrytis and powdery mildew Phenylalanine ammonia lyase (PAL) bacterial and fungat pathogens like Botrytis and powdery mildew Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial and fungal pathogens like Effected target or expressed principie(s) Crop phenotype / Toierance to Botrytis and powdery mildew Osmotin bacteriai and fungal pathogens like Botrytis and powdery mildew Alpha Hordothionin bacterial and fungal pathogens like Botrytis and powdery mildew Systemin bacterial and fungal pathogens like Botryas and powdery mildew Polygalacturonase inhibitors bacterial and fungal pathogens like Botrytis and powdery mildew Prf regulatory gene bacterial and fungal pathogens like Botrytis and powdery mildew phytoalexins bacterial and fungal pathogens like Botrytis and powdery mildew B-1,3-glucanase anbsense bacteriai and fungal pathogens like Botrytis and powdery mildew receptor kinase bacteriai and fungal pathogens like Botrytis and powdery mildew Hypersensitive response eliciting bacterial and fungal pathogens like poiypeptide Botrytis and powdery mildew Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal genes pathogens Chitinases bacterial and fungal pathogens like Botrytis and powdery mildew Barnase bacterial and fungal pathogens like Botrytis and powdery mildew Glucanases bacterial and fungal pathogens like Botrytis and powdery mildew double stranded ribonuclease viruses Coat proteins viruses 17kDa or 60 kDa protein viruses Nuclear inclusion proteins eg. a or b or viruses WO 99/35913 PCT~~~IS3 Effected target or expressed principle(s) Crop phenotype / Tolerance to Nucleoprotein Pseudoubiquidn viruses Replicase viruses Bacillus thuringiensis toxins, VIP 3, iepidoptera, aphids Bacillus cereus toxins, Photorabdus and Xenorhabdus toxins 3- Hydroxysteroid oxidase lepidoptera, aphids Peroxidase lepidoptera, aphids Aminopeptidase inhibitors eg. Leucine iepidoptera, aphids aminopeptidase inhibitor Lectines lepidoptera, aphids Protease Inhibitors eg cystatin, patatin lepidoptera, aphids ribosome inactivating protein lepidoptera, aphids stilbene synthase lepidoptera, aphids, diseases HMG-CoA reductase lepidoptera, aphids Cyst nematode hatching stimulus cyst nematodes Bamase nematodes eg root knot nematodes and cyst nematodes or general diseases CBI root knot nematodes Antifeeding principles nematodes eg root knot nematodes or root cyst nematodes Table A10: crop Oil Seed rape Effected target or expressed principle(s) Crop phenotype / Tolerance to Acetolactate synthase (ALS) Sulfonylureas, imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtatides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate dioxygenase lsoxazoles such as isoxaflutol or (HPPD) Isoxachlortol, Triones such as WO 99/35913 1'CT/EP99M183 Effected target or expressed principle(s) Crop phenotype / Tolerance to mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin O-Methyl transferase altered lignin ievels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adehylosuccinQte synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihaio-4-hydroxy-benzonitriles such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides, phenylpyraZoles, pyridin derivatives, phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as selection Suifonylureas Polyphenol oxidase or Polyphenol bacterial and fungal pathogens like oxidase antisense Cylindrosporium, Phoma, Sderotinia Metallothionein bacterial and fungal pathogens like Cylindrosporium, Phoma, Sderotinia Ribonuclease bacterial and fungal pathogens like Cylindrosporium, Phoma, Scierotinia Antifungal polypeptide AIyAFP bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia oxalate oxidase bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia glucose oxidase bacterial and fungal pathogens like Cylindrosporium, Phoma, Scierotinia pyrroinitrin synthesis genes bacterial and tungal pathogens like Cylindrosporium, Phoma, Sclerotinia WO 99l35913 PCT/EP99/00183 Effected target or expressed principle(s) Crop phenotype / Toleranoa to serine/threonine kinases bacterial and fungat pathogens like Cylindrosporium, Phoma, Sclerotinia Cecropin B bacterial and fungal pathogens like Cyiindrosporium, Phoma, Scierotinia Phenyialanine ammonia lyase (PAL) bacterial and fungal pathogens like Cylindrosporium, Phoma, Scierotinia Cf genes eg. Cf 9 Cf5 Cf4Cf2 bacterial and fungal pathogens like Cylindrosporium, Phoma, Scierotinia Osmotin bacterial and fungal pathogens like Cylindrosporium, Phoma, Scierotinia Alpha Hordothionin bacteriai and fungal pathogens like Cylindrosporium, Phoma, Scierotinia Systemin bacterial and fungal pathogens like Cylindrosporium, Phoma, Scierotinia Polygalacturonase inhibttors bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia Prf regulatory gene bacterial and fungal pathogens like Cytindrosporium, Phoma, Scierotinia phytoalexins bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia B-1,3-glucanase antisense bacterial and fungal pathogens like Cylindrosporium, Phoma, Scierotinia receptor kinase bacterial and fungat pathogens like Cylindrosporium, Phoma, Scierotinia Hypersensitive response eliciting bacterial and fungal pathogens like polypeptide Cylindrosporium, Phoma, Sclerotinia Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal genes pathogens Chitinases bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia Bamase bacterial and fungal pathogens like Cyiindrosporium, Phoma, Effected target or expressed principle(s) Crop phenotype / Tolerance to Sclerotinia, nematodes Glucanases bacterial and fungal pathogens like Cylindrosporium, Phoma, Sclerotinia double stranded ribonuclease vinises Coat proteins viruses 17kDa or 60 kDa protein viruses Nuclear inclusion proteins eg. a or b or vinjses Nucleoprotein Pseudoubiquitin vinises Replicase viruses Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids Bacillus cereus toxins, Photorabdus and Xenorhabdus toxins 3- Hydroxysteroid oxidase lepidoptera, aphids Peroxidase lepidoptera, aphids Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids aminopeptidase inhibitor Lectines lepidoptera, aphids Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids CPTI
ribosome inactivating protein lepidoptera, aphids stilbene synthase lepidoptera, aphids, diseases HMG-CoA reductase lepidoptera, aphids Cyst nematode hatching stimulus cyst nematodes Bamase nematodes eg root knot nematodes and cyst nematodes CBI root knot nematodes Antifeeding principles induced at a nematodes eg root knot nematodes, root nematode feeding site cyst nematodes Table A11: Crop Brassica vegetabie (cabbage, brussel sprouts, broccoli etc.) .33-Effected target or expressed principle(s) Crop phenotype / Tolerance to Acetolactate synthase (ALS) . Sutfonylureas, lmidazolinones, Triazolopyrimidines, Pyrimidyioxybenzoates, Phtalides AcetylCoA Carboxyiase (ACCase) Aryioxyphenoxyalkanecarboxyfic acids, cyclohexanediones Hydroxyphenylpyruvate dioxygenase Isoxazo!es such as Isoxaflutol or (HPPD) Isoxachlortoi, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin 0-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihaio-4-hydroxy-benzonitriies such as Bromoxynil and loxinyl 5-Enoipyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides, phenylpyrazoles, pyridin derivatives, phenopyiate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as selection Sulfonyiureas Polyphenol oxidase or Polyphenol bacterial and fungal pathogens oxidase antisense Metallothionein bacterial and fungal pathogens Ribonuclease bacterial and fungal pathogens Antifungai polypeptide AIyAFP bacterial and fungal pathogens oxalate oxidase bacterial and fungal pathogens glucose oxidase bacteriai and fungal pathogens Effected target or expressed principle(s) Crop phenotype / Tolerance to pyrroinitrin synthesis genes bacterial and fungal pathogens serine/threonine kinases bacterial and fungal pathogens Cecropin B bacterial and fungal pathogens Phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens Cf genes eg. Cf 9 Cf5 Cf4 Ct2 bacterial and fungal pathogens Osmatir~ bacterial and fungal pathogens Alpha Hordothionin bacterial and fungal pathogens Systemin bacterial and fungal pathogens Polygalacturonase inhibitors bacterial and fungal pathogens Prt regulatory gene bacterial and fungal pathogens phytoalexins bacterial and fungal pathogens B-1,3-glucanase antisense bacterial and fungal pathogens receptor kinase bacterial and fungal pathogens Hypersensitive response eliciting bacterial and fungal pathogens polypeptide Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal genes pathogens Chitinases bacterial and fungal pathogens Bamase bacterial and fungal pathogens Glucanases bacterial and fungal pathogens double stranded ribonuclease viruses Coat proteins viruses 17kDa or 60 kDa protein viruses Nuclear inclusion proteins eg. a or b or viruses Nucleoprotein Pseudoubiquitin viruses Replicase viruses Bacillus thuringiensis toxins, VIP 3, iepidoptera, aphids Bacillus cereus toxins, Photorabdus and Xenorhabdus toxins 3- Hydroxysteroid oxidase lepidoptera, aphids Peroxidase lepidoptera, aphids Effected target or expressed principie(s) Crop phenotype / Tolerance to Aminopeptidase inhibitors eg. Leucine iepidoptera, aphids aminopeptidase inhibitor Lectines iepidoptera, aphids Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids CPTI
ribosome inact'riating protein lepidoptera, aphids stilbene synthase lepidoptera, aphids, diseases HMG-CoA reductase lepidoptera, aphids Cyst nematode hatching stimulus cyst nematodes Bamase nematodes eg root knot nematodes and cyst nematodes CBI root knot nematodes Antifeeding principles induced at a nematodes eg root knot nematodes, root nematode feeding site cyst nematodes Table A12: Crop Pome fruits eg apples, pears Effected target or expressed principle(s) Crop phenotype / Toierance to Acetolactate synthase (ALS) Sulfonylureas, imidazoiinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtatides AcetylCoA Carboxylase (ACCase) Aryioxyphenoxyaikanecarboxytic acids, cyclohexanediones Hydroxyphenylpyruvate dioxygenase isoxazoies such as Isoxaflutol or (HPPD) isoxachiortoi, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin 0-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase inhibitors of adenyiosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and Effected target or expressed principle(s) Crop phenotype / Tolerance to cataboNsm Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoredu~'.ase Glyphosate or sulfosate Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides, phenyipyraazoies, pyridin derivatives, phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as selection Sulfonylureas Polyphenol oxidase or Polyphenol bacterial and fungal pathogens like oxidase antisense apple scab or firebiight Metallothionein bacterial and fungal pathogens like apple scab or fireblight Ribonuclease bacterial and tungal pathogens like apple scab or fireblight Antifungal polypeptide AIyAFP bacterial and fungal pathogens like apple scab or firebiight oxalate oxidase bacterial and fungal pathogens like apple scab or fireblight glucose oxidase bacterial and fungal pathogens like apple scab or fireblight pyrroinitrin synthesis genes bacterial and fungal pathogens like apple scab or fireblight serine/threonine kinases bacterial and fungal pathogens like apple scab or fireblight Cecropin B bacterial and fungal pathogens like apple scab or fireblight Phenylaianine ammonia lyase (PAL) bacterial and fungal pathogens like apple scab or fireblight Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial and fungal pathogens like Effected target or expressed principle(s) Crop phenotype / Tolerance to apple scab or firebUght Osmotin bacterial and fungal pathogens like apple scab or firebiight Alpha Hordothionin bacterial and fungal pathogens like apple scab or fireblight Sysiemir~ bacterial and tungal patnogens iiKe apple scab or firebiight Polygalacturonase inhibitors bacterial and fungal pathogens like apple scab or fireblight Prf regulatory gene bacteriat and fungal pathogens like apple scab or fireblight phytoalexins bacterial and fungal pathogens like apple scab or fireblight B-1,3-glucanase antisense bacterial and fungal pathogens like apple scab or fireblight receptor kinase bacterial and fungal pathogens like apple scab or fireblight Hypersensitive response eliciting bacterial and fungal pathogens like polypeptide apple scab or fireblight Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal genes pathogens Lytic protein bacterial and fungal pathogens Gke apple scab or fireblight Lysozym bacterial and fungal pathogens like apple scab or firebiight Chitinases bacteriai and fungal pathogens like apple scab or fireblight Bamase bacterial and fungal pathogens like apple scab or fireblight Glucanases bacterial and fungal pathogens like apple scab or fireblight WO 99/35913 PCT~~/00183 .38.

Effected target or expressed principle(s) Crop phenotype / Tolerance to double stranded ribonuclease viruses Coat proteins viruses 17kDa or 60 kDa protein viruses Nuclear inclusion proteins eg. a or b or vinms Nucleoprotein Pseudoubiquitin viruses Replicase viruses Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites Bacillus cereus toxins, Photorabdus and Xenorhabdus toxins 3- Hydroxysteroid oxidase lepidoptera, aphids, mites Peroxidase lepidoptera, aphids, mites Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites aminopeptidase inhibitor Lectines lepidoptera, aphids, mites Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites CPTI
ribosome inactivating protein lepidoptera, aphids, mites stilbene synthase lepidoptera, aphids, diseases, mites HMG-CoA reductase lepidoptera, aphids, mites Cyst nematode hatching stimulus cyst nematodes Bamase nematodes eg root knot nematodes and cyst nematodes CBI root knot nematodes Antifeeding principles induced at a nematodes eg root knot nematodes, root nematode feeding site cyst nematodes Table A13: Crop Melons Effected target or expressed principle(s) Crop phenotype / Tolerance to Acetolactate synthase (ALS) Sulfonyiureas, Imidazolinones, Triazolopyrimidines, WO 99/35913 pCT/EP"/00183 Effected target or expressed principie(s) Crop phenotype / Tolerance to Pyrimidyioxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyaikanecarboxyiic acids, cyclohexanediones Hydroxyphenylpyruvate dioxygenase isoxazoies such as isoxafiutol or (HPPD) isoxachtortoi, Triones such as mesoftne or suicotrione Phosphinothricin acetyl transferase Phosphinothricin 0-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihaio-4-hydroxy-benzonitriies such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides, phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as selection Sutfonylureas Polyphenol oxidase or Polyphenol bacteriai or fungal pathogens like oxidase antisense phytophtora Metallothionein bacterial or fungal pathogens like phytophtora Ribonuclease bacterial or fungal pathogens like phytophtora Antifungal polypeptide AIyAFP bacterial or fungal pathogens like phytophtora WO 99/35913 PCT/EP"/00183 Effected target or expressed principie(s) Crop phenotype / Toierance to oxalate oxidase bacterial or fungal pathogens like phytophtora glucose oxidase bacterial or fungal pathogens iike phytophtora pyrroinitrin synthesis genes bacteriai or fungal pathogens iike phytophtora serine/threonine kinases bacterial or fungal pathogens like phytophtora Cecropin B bacterial or fungal pathogens like phytophtora Phenyiaianine ammonia lyase (PAL) bacterial or fungal pathogens like phytophtora Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens like phytophtora Osmotin bacterial or fungal pathogens like phytophtora Alpha Hordothionin bacterial or fungal pathogens like phytophtora Systemin bacterial or fungal pathogens like phytophtora Polygalacturonase inhibitors bacterial or fungal pathogens like phytophtora Prf regulatory gene bacterial or fungal pathogens like phytophtora -phytoalexins bacterial or fungal pathogens like phytophtora B-1,3-giucanase antisense bacterial or fungal pathogens like phytophtora receptor kinase bacterial or fungal pathogens like phytophtora Hypersensitive response eiiciting bacterial or fungal pathogens like polypeptide phytophtora Effected target or expressed principle(s) Crop phenotype / Toierance to Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodai genes pathogens Lytic protein bacterial or fungal pathogens like phytophtora Lysozym bacterial or fungal pathogens like phytophtora Chitinases bacterial or fungal pathogens like phytophtora Bamase bacterial or fungal pathogens like phytophtora Glucanases bacterial or fungal pathogens like phytophtora double stranded ribonuclease viruses as CMV,, PRSV, WMV2, SMV, ZYMV . l Coat proteins viruses as CMV,, PRSV, WMV2, SMV, ZYMV
17kDa or 60 kDa protein viruses as CMV,, PRSV, WMV2, SMV, ZYMV
Nuciear inclusion proteins eg. a or b or viruses as CMV,, PRSV, WMV2, SMV, Nucleoprotein ZYMV
Pseudoubiquitin viruses as CMV,, PRSV, WMV2, SMV, ZYMV
Replicase viruses as CMV,, PRSV, WMV2, SMV, ZYMV
Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites Bacillus cereus toxins, Photorabdus and Xenorhabdus toxins 3- Hydroxysteroid oxidase lepidoptera, aphids, mites, whitefly Peroxidase iepidoptera, aphids, mites, whitefiy Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites, whitefiy aminopeptidase inhibitor WO 99/35913 PCT/Ep"/001 83 Effected target or expressed principie(s) Crop phenotype / Toierance to Lectines lepidoptera, aphids, mites, whitefiy Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites, whitefiy CPTI, virgiferin ribosome inactivating protein iepidoptera, aphids, mites, whitefiy stilbene synthase iepidoptera, aphids, mites, whftefly HMG-CaA reductase fepidoptera, aphids, mites, wnitefly Cyst nematode hatching stimulus cyst nematodes Bamase nematodes eg root knot nematodes and cyst nematodes CBI root knot nematodes Antifeeding principles induced at a nematodes eg root knot nematodes, root nematode feeding site cyst nematodes Table A14: Crop Banana Effected target or expressed principle(s) Crop phenotype / Toierance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryioxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or (HPPD) Isoxachlortol, Triones such as mesotrione or suicotrione Phosphinothricin acetyl transferase Phosphinothricin 0-Methyl transf erase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-ben2onitriles such Effected target or expressed principle(s) Crop phenotype / Toierance to as Bromoxynii and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or suifosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides, phenylpyrazoles, pyridin denvativps, phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as selection Sulfonylureas Polyphenol oxidase or Polyphenol bacterial or fungal pathogens oxidase antisense Metallothionein bacterial or fungal pathogens Ribonuclease bacterial or fungal pathogens Antifungal polypeptide AIyAFP bacterial or fungal pathogens oxalate oxidase bacterial or fungal pathogens glucose oxidase bacterial or fungal pathogens pyrrolnitrin synthesis genes bacterial or fungal pathogens serine/threonine kinases bacterial or fungal pathogens Cecropin B bacterial or fungal pathogens Phenylalanine ammonia lyase (PAL) bacterial or fungal pathogens Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens Osmotin bacterial or fungal pathogens Alpha Hordothionin bacterial or fungal pathogens Systemin bacterial or fungal pathogens Polygalacturonase inhibitors bacterial or fungal pathogens Prf regulatory gene bacterial or fungal pathogens phytoalexins bacterial or fungal pathogens B-1,3-glucanase antisense bacterial or fungal pathogens receptor kinase bacterial or fungal pathogens Hypersensitive response eiiciting bacterial or tungal pathogens polypeptide Systemic acquires resistance (SAR) viral, bacterial, tungal, nematodai WO 99/35913 pCT~~/00193 Effected target or expressed principle(s) Crop phenotype / Tolerance to genes pathogens Lytic protein bacterial or fungal pathogens Lysozym bacterial or fungal pathogens Chftinases bacterial or fungal pathogens Bamase bacterial or fungal pathogens Glucanases bacterial or fungal pathogens double stranded ribonuclease viruses as Banana bunchy top virus (BBTV) Coat proteins viruses as Banana bunchy top virus (BBTV) 17kDa or 60 kDa protein viruses as Banana bunchy top virus (BBTV) Nuclear inciusion proteins eg. a or b or viruses as Banana bunchy top virus Nucleoprotein (BBTV) Pseudoubiquitin viruses as Banana bunchy top virus (BBTV) Replicase viruses as Banana bunchy top virus (BBTV) Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites, nematodes Bacillus cereus toxins, Photorabdus and Xenorhabdus toxins 3- Hydroxysteroid oxidase lepidoptera, aphids, mites, nematodes Peroxidase lepidoptera, aphids, mites, nematodes Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites, nematodes aminopeptidase inhibitor Lectines lepidoptera, aphids, mites, nematodes Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites, nematodes CPTI, virgiferin ribosome inactivating protein lepidoptera, aphids, mites, nematodes stilbene synthase lepidoptera, aphids, mites, nematodes HMG-CoA reductase tepidoptera, aphids, mites, nematodes Cyst nematode hatching stimulus cyst nematodes .45-Effected target or expressed principle(s) Crop phenotype / Tolerance to Bamase nematodes eg root knot nematodes and cyst nematodes CBI root knot nematodes Antifeeding principles induced at a nematodes eg root knot nematodes, root nematode feeding site cyst nematodes Table A 15: Crop Cotton Effected target or expressed principle(s) Crop phenotype / Tolerance to Acetolactate synthase (ALS) Sulfonylureas, tmidazolinones, Triazoiopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaftutol or (HPPD) Isoxachiortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin 0-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides, phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc.

Effected target or expressed principle(s) Crop phenotype / Tolerance to Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as selection Sulfonylureas Polyphenol oxidase or Polyphenol bacterial or fungai pathogens oxidase antisense Metallothionein bacterial or fungal pathogens Ribonuclease bacterial or fungai pathogens Antifungal polypeptide AfyAFP bacterial or fungal pathogens oxalate oxidase bacterial or fungal pathogens glucose oxidase bacterial or fungal pathogens pyrroinitrin synthesis genes bacterial or fungal pathogens serine/threonine kinases bacterial or fungal pathogens Cecropin B bacterial or fungal pathogens Phenylaianine ammonia iyase (PAL) bacterial or fungal pathogens Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens Osmotin bacterial or fungal pathogens Alpha Hordothionin bacterial or fungal pathogens Systemin bacterial or fungal pathogens Polygalacturonase inhibitors bacterial or fungal pathogens Prf regulatory gene bacterial or fungal pathogens phytoalexins bacterial or fungal pathogens B-1,3-glucanase antisense bacterial or fungal pathogens receptor kinase bacterial or fungal pathogens Hypersensitive response eliciting bacterial or fungal pathogens polypeptide Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal genes pathogens Lytic protein bacterial or fungal pathogens Lysozym bacterial or fungal pathogens Chitinases bacterial or fungal pathogens Bamase bacterial or fungal pathogens Glucanases bacterial or tungal pathogens double stranded ribonuclease viruses as wound tumor virus (WTV) Effected target or expressed principie(s) Crop phenotype / Toierance to Coat proteins viruses as wound tumor virus (WTV) 17kDa or 60 kDa protein viruses as wound tumor virus (WTV) Nuclear inclusion proteins eg. a or b or viruses as wound tumor virus (WTV) Nucleoprotein Pseudoubiquitin viruses as wound tumor virus (WTV) Repiicase viruses as wound tumor virus (WTV) Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites, nematodes, Bacillus cereus toxins, Photorabdus and whitefly Xenorhabdus toxins 3- Hydroxysteroid oxidase iepidoptera, aphids, mites, nematodes, whitefly Peroxidase iepidoptera, aphids, mites, nematodes, whitefly Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites, nematodes, aminopeptidase inhibitor whitefly Lectines lepidoptera, aphids, mites, nematodes, whitefly Protease Inhibitors eg cystatin, patatin, iepidoptera, aphids, mites, nematodes, CPTI, virgiferin whitefly ribosome inactivating protein lepidoptera, aphids, mites, nematodes, whitefly stilbene synthase lepidoptera, aphids, mites, nematodes, whitefly HMG-CoA reductase lepidoptera, aphids, mites, nematodes, whitefly Cyst nematode hatching stimulus cyst nematodes Bamase nematodes eg root knot nematodes and cyst nematodes CBI root knot nematodes Antifeeding principles induced at a nematodes eg root knot nematodes, root nematode feeding site cyst nematodes WO 99/35913 pCT~~100183 Tabte A 16: Crop Sugarcane Effected target or expressed principte(s) Crop phenotype / Tolerance to Acetolactate synthase (ALS) Suffonylureas, Imidazolinones, Triazolopyrimidines, Pyrimidyioxybenzoates, Phtalides AcetylCcA Carboxylese (ACCase) Aryioxyphenoxyalkenecarboxytic acids, cyclohexanediones Hydroxyphenylpyruvate dioxygenase lsoxazotes such as Isoxaftutol or (HPPD) Isoxachlortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin 0-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihato-4-hydroxy-benzonitrites such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides, phenylpyrazotes, pyridin derivatives, phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as selection Sulfonylureas Polyphenol oxidase or Potyphenol bacterial or fungal pathogens oxidase antisense Metallothionein bacterial or tungal pathogens Ribonuclease bacterial or fungal pathogens Antifungal polypeptide AIyAFP bacterial or fungal pathogens WO 99/35913 pCT/EP"/00183 Effected target or expressed principle(s) Crop phenotype / Tolerance to oxalate oxidase bacterial or fungal pathogens glucose oxidase bacterial or fungal pathogens pyrroinitrin synthesis genes bacterial or fungal pathogens serine/threonine kinases bacterial or fungal pathogens Cecropin B bacterial or fungal pathogens Phenylatanine ammonia lyase (PAL) bacterial or fungal pathogens Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens Osmotin bacterial or fungal pathogens Alpha Hordothionin bacterial or fungal pathogens Systemin bacterial or fungal pathogens Polygalacturonase inhibitors bacterial or fungal pathogens Prf regulatory gene bacterial or fungal pathogens phytoalexins bacterial or fungal pathogens B-1,3-glucanase antisense bacterial or fungal pathogens receptor kinase bacterial or fungal pathogens Hypersensitive response eliciting bacterial or fungal pathogens polypeptide Systemic acquires resistance (SAR) virai, bacterial, fungal, nematodal genes pathogens Lytic protein bacterial or fungal pathogens Lysozym bacterial or fungal pathogens eg clavibacter Chitinases bacterial or fungal pathogens Bamase bacterial or fungal pathogens Glucanases bacterial or fungal pathogens double stranded ribonuclease viruses as SCMV, SrMV
Coat proteins viruses as SCMV, SrMV
17kDa or 60 kDa protein viruses as SCMV, SrMV
Nuclear inclusion proteins eg. a or b or viruses as SCMV, SrMV
Nucleoprotein Pseudoubiquitin viruses as SCMV, SrMV
Replicase viruses as SCMV, SrMV

WO 99/35913 PL"T/EP99/00183 . 50 .

Effected target or expressed principle(s) Crop phenotype / Tolerance to Bacillus thuringiensis toxins, VIP 3, iepidoptera, aphids, mites, nematodes, Bacillus cereus toxins, Photorabdus and whitefiy, beeties eg mexican rice borer Xenorhabdus toxins 3- Hydroxysteroid oxidase iepidoptera, aphids, mites, nematodes, whitefiy, beetles eg mexican rice borer Peroxidase iepkloptera, aphids, mites. nematodes, whitefly, beetles eg mexican rice borer Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites, nematodes, aminopeptidase inhibitor whitefly, beetles eg mexican rice borer Lectines iepidoptera, aphids, mites, nematodes, whitefiy, beetles eg mexican rice borer Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites, nematodes, CPTI, virgiferin whitefly, beetles eg mexican rice borer ribosome inactivating protein lepidoptera, aphids, mites, nematodes, whitefly, beetles eg mexican rice borer stilbene synthase lepidoptera, aphids, mites, nematodes, whitefly, beetles eg mexican rice borer HMG-CoA reductase lepidoptera, aphids, mites, nematodes, whitefly, beetles eg mexican rice borer Cyst nematode hatching stimulus cyst nematodes Bamase nematodes eg root knot nematodes and cyst nematodes CBI root knot nematodes Antifeeding principles induced at a nematodes eg root knot nematodes, root nematode feeding site cyst nematodes Table A 17: Crop Sunflower Effected target or expressed principle(s) Crop phenotype / Toierance to Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones, Effected target or expressed principie(s) Crop phenotype / Tolerance to Triazoiopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryioxyphenoxyalkanecarboxylic acids, cyclohexanediones Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxafiutol or (HPPD) Isoxacniortol, Triones such as mesotrione or suicotrione Phosphinothricin acetyl transferase Phosphinothricin 0-Methyl transferase altered lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihalo-4-hydroxy-benzonitriies such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or suifosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides, phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as selection Sulfonyiureas Polyphenol oxidase or Polyphenol bacterial or tungal pathogens oxidase antisense Metallothionein bacterial or fungal pathogens Ribonuclease bacterial or fungal pathogens Antifungal polypeptide AIyAFP bacterial or fungal pathogens oxalate oxidase bacterial or fungal pathogens eg scierotinia glucose oxidase bacterial or fungal pathogens WO 99/35913 PCT/EP99l00183 Effected target or expressed principle(s) Crop phenotype / Toierance to pyrroinitrin synthesis genes bacterial or fungal pathogens serine/threonine kinases bacterial or fungal pathogens Cecropin B bacterial or fungal pathogens Phenyiafanine ammonia iyase (PAL) bacteriai or fungal pathogens Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacteriai or fungai pathogens Osmatin bacterial or tungat pathogens Alpha Hordothionin bacteriai or fungal pathogens Systemin bacteriai or fungal pathogens Polygalacturonase inhibitors bacterial or fungal pathogens Prf regulatory gene bacteriai or fungal pathogens phytoalexins bacterial or fungal pathogens B-1,3-giucanase antisense bacterial or fungal pathogens receptor kinase bacterial or fungal pathogens Hypersensitive response eliciting bacterial or fungal pathogens polypeptide Systemic acquires resistance (SAR) viral, bacteriai, fungal, nematodal genes pathogens Lytic protein bacterial or fungal pathogens Lysozym bacterial or fungal pathogens Chitinases bacterial or fungal pathogens Bamase bacteriai or fungal pathogens Glucanases bacterial or fungal pathogens double stranded ribonuciease viruses as CMV, TMV
Coat proteins viruses as CMV, TMV
17kDa or 60 kDa protein viruses as CMV, TMV
Nuclear inclusion proteins eg. a or b or viruses as CMV, TMV
Nucleoprotein Pseudoubiquitin viruses as CMV, TMV
Replicase viruses as CMV, TMV
Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites, nematodes, Bacillus cereus toxins, Photorabdus and whitefiy, beeties Xenorhabdus toxins WO 99/35913 PCT/EP"M

Effected target or expressed principle(s) Crop phenotype / Toierance to 3- Hydroxysteroid oxidase iepidoptera, aphids, mites, nematodes, whitefly, beetles Peroxidase iepidoptera, aphids, mites, nematodes, whitefly, beetles Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites, nematodes, aminopeptidase inhibitor whitefly, beeties Lectines lepidoptera, aphids, mites, nematodes, whitefly, beetles Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites, nematodes, CPTI, virgiferin whitefly, beetles ribosome inactivating protein iepidoptera, aphids, mites, nematodes, whitefly, beetles stilbene synthase iepidoptera, aphids, mites, nematodes, whitefly, beetles HMG-CoA reductase lepidoptera, aphids, mites, nematodes, whitefly, beetles Cyst nematode hatching stimulus cyst nematodes Bamase nematodes eg root knot nematodes and cyst nematodes CBI root knot nematodes Antifeeding principles induced at a nematodes eg root knot nematodes, root nematode feeding site cyst nematodes Table A 18: Crop Sugarbeet, Beet root Effected target or expressed principle(s) Crop phenotype / Tolerance to Acetolactate synthase (ALS) Sulfonylureas, lmidazolinones, Triazolopyrimidines, Pyrimidyloxybenzoates, Phtalides AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids, Effected target or expressed principie(s) Crop phenotype / Toierance to cyclohexanediones Hydroxyphenylpyruvate dioxygenase lsoxazoles such as isoxaflutol or (HPPD) isoxachtortol, Triones such as mesotrione or sulcotrione Phosphinothricin acetyl transferase Phosphinothricin O-Methyl transferase alterrd lignin levels Glutamine synthetase Glufosinate, Bialaphos Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis Anthranilate Synthase Inhibitors of tryptophan synthesis and catabolism Nitrilase 3,5-dihaio-4-hydroxy-benzonitriies such as Bromoxynil and loxinyl 5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate Synthase (EPSPS) Glyphosate oxidoreductase Glyphosate or sulfosate Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides, phenylpyrazoles, pyridin derivatives, phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as selection Sulfonylureas Polyphenol oxidase or Polyphenol bacterial or fungal pathogens oxidase antisense Metallothionein bacterial or fungal pathogens Ribonuclease bacterial or fungal pathogens Antifungal polypeptide AIyAFP bacterial or fungal pathogens oxalate oxidase bacterial or fungal pathogens eg scierotinia glucose oxidase bacterial or fungal pathogens pyrroinitrin synthesis genes bacterial or fungal pathogens serine/threonine kinases bacterial or fungal pathogens Cecropin B bacteriai or fungal pathogens WO 99/35913 PCT/EP"/00183 Effected target or expressed principle(s) Crop phenotype / Toleranoe to Phenylalanine ammonia iyase (PAL) bacterial or fungal pathogens Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens Osmotin bacterial or fungal pathogens Alpha Hordothionin bacterial or fungal pathogens Systemin bacterial or fungal pathogens Polygalacturonase inhibitors bacterial or funga! rathoge.~.s Prf regulatory gene bacterial or fungal pathogens phytoalexins bacterial or fungal pathogens B-1,3-glucanase antisense bacterial or fungal pathogens AX + W!N proteins bacterial or fungal pathogens like Cercospora beticola receptor kinase bacterial or fungal pathogens Hypersensitive response eliciting bacterial or fungal pathogens polypeptide Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal genes pathogens Lytic protein bacterial or fungai pathogens Lysozym bacterial or fungal pathogens Chitinases bacterial or fungal pathogens Bamase bacterial or fungal pathogens Glucanases bacterial or fungal pathogens double stranded ribonuclease viruses as BNYVV
Coat proteins viruses as BNYVV
17kDa or 60 kDa protein viruses as BNYVV
Nuclear inclusion proteins eg. a or b or viruses as BNYVV
Nucleoprotein Pseudoubiquitin viruses as BNYVV
Replicase viruses as BNYVV
Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites, nematodes, Bacillus cereus toxins, Photorabdus and whitefly, beetles, rootflies Xenorhabdus toxins 3- Hydroxysteroid oxidase lepidoptera, aphids, mites, nematodes, Effected target or expressed principle(s) Crop phenotype / Tolerance to whitefiy, beeties, rootflies Peroxidase lepidoptera, aphids, mites, nematodes, whitefly, beetles, rootflies Aminopeptidase inhibttors eg. Leucine iepidoptera, aphids, mites, nematodes, aminopeptidase inhibitor whitefly, beetles, rootflies Lectines lepidoptera, aphids, mites, nematodes, whitefly, beetles, rootfiies Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites, nematodes, CPTI, virgiferin whitefly, beetles, rootflies ribosome inactivating protein lepidoptera, aphids, mites, nematodes, whitefly, beetles, rootflies stilbene synthase lepidoptera, aphids, mites, nematodes, whftefly, beetles, rootflies HMG-CoA reductase lepidoptera, aphids, mites, nematodes, whitefly, beetles, rootfiies Cyst nematode hatching stimulus cyst nematodes Bamase nematodes eg root knot nematodes and cyst nematodes Beet cyst nematode resistance locus cyst nematodes CBI root knot nematodes Antifeeding principles induced at a nematodes eg root knot nematodes, root nematode feeding site cyst nematodes The abovementioned animal pests which can be controlled by the method according to the invention include; for example, insects, representatives of the order acarina and representatives of the class nematoda; especially from the order Lepidoptera Acieris spp., Adoxophyes spp., especially Adoxophyes reticulana; Aegeria spp., Agrotis spp., especially Agrotis spinifera; Alabama argillaceae, Amylois spp., Anticarsia gemmatalis, Archips spp., Argyrotaenia spp., Autographa spp., Busseola fusca, Cadra cautelia, Carposina nipponensis, Chilo spp., Choristoneura spp., Clysia ambiguella, Cnaphalocrocis spp., Cnephasia spp., Cochylis spp., Coleophora spp., Crocidolomia binotalis, Cryptophlebia leucotreta, Cydia spp., especially Cydia pomonella;

Diatraea spp., Diparopsis castanea, Earias spp., Ephestfa spp., especially E.
KhiinieUa;
Eucosma spp., Eupoecilia ambiguelia, Euproctis spp., Euxoa spp., Grapholita spp., Hedya nubiferana, Heliothis spp., especially H. Virescens und H. zea; Hellula undalis, Hyphantria cunea, Keiferia lycopersicella, Leucoptera scitella, Lithocollethis spp., Lobesiaspp., Lymantria spp., Lyonetia spp., Malacosoma spp., Mamestra brassicae, Manduca sexta, Operophtera spp., Ostrinia nubilaiis, Pammene spp., Pandemis spp., Panolis flammea, Pectinophora spp.. Phthorimaea operculetla, Pieris rapae, Pleris spp., Plutelia xylostella, Prays spp., Scirpophaga spp., Sesamia spp., Sparganothis spp., Spodopteralittoralis, Synanthedon spp., Thaumetopoea spp., Tortrix spp., Trichoplusia ni and Yponomeuta spp.;
from the order Coleoptera, for example Agriotes spp., Anthonomus spp., Atomaria linearis, Chaetocnema tibialis, Cosmopolites spp., Curculio spp., Dermestes spp., Diabrotica spp., Epilachna spp., Eremnus spp., Leptinotarsa decemlineata, Lissorhoptrus spp., Melolontha spp., Oryzaephilus spp., Otiorhynchus spp., Phlyctinus spp., Popillia spp., Psylliodes spp., Rhizopertha spp., Scarabeidae, Sitophilus spp., Sitotroga spp., Tenebrio spp., Tribolium spp. and Trogoderma spp.;

from the order Orthoptera, for example Blatta spp., Blattella spp., Gryllotalpa spp., Leucophaea maderae, Locusta spp., Periplaneta spp. and Schistocerca spp.;
from the order isoptera, for example Reticulitermes spp.;

from the order Psocoptera, for example Liposcelis spp.;

from the order Anoplura, for example Haematopinus spp., Linognathus spp., Pediculus spp., Pemphigus spp. and Phylloxera spp.;

from the order Mallophaga, for example Damalinea spp. and Trichodectes spp.;
from the order Thysanoptera, for example Frankliniella spp., Hercinothrips spp., Taeniothrips spp., Thrips paimi, Thrips tabaci and Scirtothrips aurantii;

from the order Heteroptera, for example Cimex spp., Distantiella theobroma, Dysdercus spp., Euchistus spp. Eurygaster spp. Leptocorisa spp., Nezara spp., Piesma spp., Rhodnius spp., Sahlbergella singularis, Scotinophara spp. and Triatoma spp.;

from the order Homoptera, for example Aleurothrixus floccosus, Aleyrodes brassicae, Aonidiella aurantii, Aphididae, Aphis craccivora, A. fabae, A. gosypii;
Aspidiotus spp., Bemisia tabaci, Ceroplaster spp., Chrysomphalus aonidium, Chrysomphalus dictyospermi, Coccus hesperidum, Empoasca spp., Eriosoma lanigerum, Erythroneura spp., Gascardia WO 99/35913 pCT/EP"/00193 spp., Laodelphax spp., Lecanium comi, Lepidosaphes spp., Macrosiphus spp., Myzus spp., especially M.persicae; Nephotetax spp., especially N. cincticeps; Nilaparvata spp., especially N. lugens; Paratoria spp., Pemphigus spp., Planococcus spp., Pseudaulacaspis spp., Pseudococcus spp., especially P. Fragiiis, P. citriculus and P.
comstocki; Psylia spp., especially P. pyri; Pulvlnaria aethiopica, Duadraspidiotus app., Rhopalosiphum spp., Saissetia spp., Scaphoideus spp., Schizaphis spp., Sitobion spp., Trialeurodes vaporariorum, Trioza erytreae and Unaspis citri;

from the order Hymenoptera, for example Acromyrmex, Atta spp., Cephus spp., Diprion spp., Diprionidae, Gilpinia polytoma, Hoplocampa spp., Lasius spp., Monomorium pharaonis, Neodiprion spp., Solenopsis spp. and Vespa spp.;

from the order Diptera, for example Aedes spp., Antherigona soccata, Bibio hortulanus, Calliphora erythrocephala, Ceratitis spp., Chrysomyia spp., Culex spp., Cuterebra spp., Dacus spp., Drosophila melanogaster, Fannia spp., Gastrophilus spp., Glossina spp., Hypoderma spp., Hyppobosca spp., Liriomyza spp., Lucilia spp., Melanagromyza spp., Musca spp., Oestrus spp., Orseolia spp., Oscinelia frit, Pegomyia hyoscyami, Phorbia spp., Rhagoletis pomonella, Sciara spp., Stomoxys spp., Tabanus spp., Tannia spp.
and Tipula spp.;

from the order Siphonaptera, for example Ceratophyllus spp. and Xenopsylla cheopis;
from the order Thysanura, for example Lepisma saccharina and from the order Acarina, for example Acarus siro, Aceria sheldoni; Aculus spp., especially A.
schlechtendaii; Amblyomma spp., Argas spp., Boophilus spp., Brevipaipus spp., especially B. califomicus and B. phoenicis; Bryobia praetiosa, Calipitrimerus spp:, Chorioptes app., Dermanyssus gallinae, Eotetranychus spp., especially E.carpini and E.
orientalis; Eriophyes spp., especially E. vitis; Hyalomma spp., Ixodes spp., Olygonychus pratensis, Omithodoros spp., Panonychus spp., especially P. ulmi and P. citri; Phyllocoptruta spp., especially P.
oleivora; Polyphagotarsonemus spp., especially P. latus; Psoroptes spp., Rhipicephalus spp., Rhizoglyphus spp., Sarcoptes spp., Tarsonemus spp. and Tetranychus spp., in particular T. urticae, T. cinnabarinus and T. Kanzawai;

representatives of the class Nematoda;

(1) nematodes selected from the group consisting of root knot nematodes, cyst-forming nematodes, stem eelworms and foliar nematodes;

(2) nematodes selected from the group consisting of Anguina spp.;
Aphelenchoides spp.;
Ditylenchus spp.; Globodera spp., for example Globodera rostochiensis;
Heterodera spp., for example Heterodera avenae, Heterodera glycines, Heterodera schachtii or Heterodera trifolii; Longidorus spp.; Meloidogyne spp., for example Meloidogyne incognita or Meloidogyne javanica; Pratylenchus, for example Pratylenchus neglectans or Pratylenchus penetrans; Radopholus spp., for example Radopholus similis; Trichodorus spp.;
Tylenchulus, for example Tylerichulus semipenetrans; and Xiphinema spp.; or (3) nematodes selected from the group consisting of Heterodera spp., for example Heterodera glycines; and Meloidogyne spp., for example Meloidogyne incognita.

The method according to the invention allows pests of the abovementioned type to be controlled, i.e. contained or destroyed, which occur, in pardcular, on transgenic plants, mainly useful plants and omamentals in agriculture, in horticulture and in forests, or on parts, such as fruits, flowers, foliage, stalks, tubers or roots, of such plants, the protection against these pests in some cases even extending to plant parts which form at a later point in time.

The method according to the invention can be employed advantageously for controlling pests in rice, cereals such as maize or sorghum; in fruit, for example stone fruit, pome fruit and soft fruit such as apples, pears, plums, peaches, almonds, cherries or berries, for example strawberries, raspberries and blackberries; in legumes such as beans, lentils, peas or soya beans; in oil crops such as oilseed rape, mustard, poppies, olives, sunflowers, coconuts, castor-oil plants, cacao or peanuts; in the marrow famiiy such as pumpkins, cucumbers or melons; in fibre plants such as cotton, flax, hemp or jute; in citrus fruit such as oranges, lemons, grapefruit or tangerines; in vegetables such as spinach, lettuce, asparagus, cabbage species, carrots, onions, tomatoes, potatoes, beet or capsicum; in the laurel family such as avocado, Cinnamonium or camphor; or in tobacco, nuts, coffee, egg plants, sugar cane, tea, pepper, grapevines, hops, the banana family, latex plants or omamentals, mainly in maize, rice, cereals, soya beans, tomatoes, cotton, potatoes, sugar beet, rice and mustard; in particular in cotton, rice, soya beans, potatoes and maize.

It has emerged that the method according to the invention is valuable preventatively and/or curatively in the field of pest control even at low use concentrations of the pesticidal composition and that a very favourable biocidal spectrum is achieved thereby.
Combined with a favourable compatibility of the composition employed with warm-blooded species, fish and plants, the method according to the invention can be employed against all or individual developmental stages of normally-sensitive; but also of normally-resistant, animal pests such as insects and representatives of the order Acarina, depending on the species of the transgenic crop plant to be protected from attack by pests. The insecticidal and/or acaricidal effect of the method according to the invention may become apparent directly, i.e.
in a destruction of the pests which occurs immediately or only after some time has elapsed, for example, during ecdysis. or indirectly, for example as a reduced oviposftion and/or hatching rate, the good action corresponding to a destruction rate (mortality) of at least 40 to 50%.

Depending on the intended aims and the prevailing circumstances, the pesticides within the scope of invention , which are known per se, are emuisifiable concentrates, suspension concentrates, directly sprayable or dilutable solutions, spreadable pastes, dilute emulsions, wettable powders, soluble powders, dispersible powders, wettable powders, dusts, granules or encapsulations in polymeric substances which comprise a nitroimino- or nitroguanidino-compound.

The active ingredients are employed in these compositions together with at least one of the auxiliaries conventionally used in art of formulation, such as extenders, for example solvents or solid carriers, or such as surface-active compounds (surfactants).

Formulation auxiliaries which are used are, for example, solid carriers, solvents, stabilizers, "slow release" auxiliaries, colourants and, if appropriate, surface-active substances (surfactants). Suitable carriers and auxiliaries are all those substances which are con-ventionally used for crop protection products. Suitable auxiliaries such as solvents, solid carriers, surface-active compounds, non-ionic surfactants, cationic surfactants, anionic surfactants and other auxiliaries in the compositions employed according to the invention are, for example, those which have been described in EP-A-736 252.

These compositions for controlling pests can be formulated, for example, as wettable powders, dusts, granules, solutions, emulsifiable concentrates, emulsions, suspension concentrates or aerosols. For example, the compositions are of the type described in EP-A-736 252.

The action of the compositions within the scope of invention which comprise a nitroimino- or nitroguanidino-compound can be extended substantially and adapted to prevailing circumstances by adding other insecticidally, acaricidally and/or fungicidally active ingredients. Suitable examples of added active ingredients are representatives of the following classes of active ingredients: organophosphorous compounds, nitrophenois and derivatives, formamidines, ureas, carbamates, pyrethroids, chlorinated hydrocarbons;
especially preferred components in mixtures are, for example, abamectin, emamectin, spinosad, pymetrozine, fenoxycarb, Ti-435, fipronil, pyriproxyfen, diazinon or diafenthiuron.
As a rule, the compositions within the scope of Invention comprise 0.1 to 99%, in particular 0.1 to 95 %, of a nitroimino- or nitroguanidino-compound and 1 to 99.9 %, in particuiar 5!o 99.9 %, of - at least - one solid or liquid auxiliary, It being possible, as a rule, for 0 to 25 %, in particular 0.1 to 20 %, of the compositions to be surfactants (% in each case meaning per cent by weight). While concentrated compositions are more preferred as commercial products, the end user will, as a rule, use dilute compositions which have considerably lower concentrations of active ingredient.

The compositions according to the invention may also comprise other solid or liquid auxiliaries, such as stabilisers, for example epoxidized or unepoxidized vegetable oils (for example epoxidized coconut oil, rapeseed oil or soya bean oil), antifoams, for example silicone oil, preservatives, viscosity regulators, binders and/or tackifiers, and also fertilizers or other active ingredients for achieving specific effects, for example, bactericides, fungicides, nematicides, molluscicides or herbicides.

The compositions according to the invention are produced in a known manner, for example prior to mixing with the auxiliary/auxiliaries by grinding, screening and/or compressing the active ingredient, for example to give a particular particie size, and by intimately mixing and/or grinding the active ingredient with the auxiliary/auxiliaries. :.

The method according to the. invention for controlling pests of the abovementioned type is carried out in a manner known per se to those skilled in the art, depending on the intended aims and prevailing circumstances, that is to say by spraying, wetting, atomizing, dusting, brushing on, seed dressing, scattering or pouring of the composition. Typical use concen-trations are between 0.1 and 1000 ppm, preferably between 0.1 and 500 ppm of active ingredient. The application rate may vary within wide ranges and depends on the soil constitution, the type of application (foliar application; seed dressing;
application in the seed furrow), the transgenic crop plant, the pest to be controlled, the climatic circumstances prevailing in each case, and other factors determined by the type of application, timing of application and target crop. The application rates per hectare are generaily 1 to 2000 g of nitroimino- or nitroguanidino-compound per hectare, in particular 10 to 1000 g/ha, preferably to 500 g/ha, especially preferably 10 to 200 glha.

A preferred type of application in the field of crop protection within the scope of invention is application to the foliage of the plants (foliar application), it being possible to adapt frequency and rate of application to the risk of infestation with the pest in question..
However, the active ingredient may also enter into the plants via the root system (systemic action), by drenching the site of the plants with a liquid ccmposition or by incorporating the active ingredient in solid form into the site of the plants, for example into the soil, for example in the form of granules (soil application). In the case of paddy rice crops, such granules may be metered into the flooded paddy field.

The compositions according to invention are also suitable for protecting propagation material of transgenic plants, for example seed, such as fruits, tubers or kemels, or plant cuttings, from animal pests, in particular insects and representatives of the order Acarina.
The propagation material can be treated with the composition prior to application, for example, seed being dressed prior to sowing. The active ingredient may also be applied to seed kemels (coating), either by soaking the kemels in a liquid composition or by coating them with a solid composition. The composition may also be applied to the site of application when applying the propagation material, for example into the seed furrow during sowing. These treatment methods for plant propagation material and the plant propagation material treated thus are a further subject of the invention.

Examples of formulations of nitroimino- or nitroguanidino-compounds which can be used in the method according to the invention , for instance solutions, granules, dusts, sprayable powders, emulsion concentrates, coated granules and suspension concentrates, are of the type as has been described in, for example, EP-A-580 553, Exampies Fl to F10.

Biological examples Table B

The following abreviations are used in the table:
Active Principle of transgenic plant: AP
Photorhabdus luminescens: PL
Xenorhabdus nematophilus: XN
Proteinase Inhibitors: Pinh.

Plant lectins PLec.
Agglutinins: Aggi.
3-Hydroxysteroid oxidase: HO
Cholesteroloxidase: CO
Chitinase: CH
Glucanase: GL
Stilbensynthase SS
Table B.

AP I Control of AP Control of B. I CryIA(a) Adoxophyes spp. B.18 CrylA(a) Ostrinia nubilalis B.2 CrylA(a) Agrotis spp. B.19 CryIA(a) Pandemis spp.
B.3 CrylA(a) Alabama B.20 CrylA(a) Pectinophora argillaceae gossyp.
B.4 CrylA(a) Anticarsia B.21 CryIA(a) Phyllocnistis citrelia gemmatalis B.22 CrylA(a) Pieris spp.
B.5 CryIA(a) Chilo spp. B.23 CryIA(a) Plutella xylostella B.6 CryIA(a) Clysia ambiguelia B.24 CryIA(a) Scirpophaga spp.
B.7 CrylA(a) Crocidolomia B.25 CrylA(a) Sesamia spp.
binotalis B.26 CryIA(a) Sparganothis spp.
B.8 CrylA(a) Cydia spp. B.27 CryIA(a) Spodoptera spp.
B.9 CrylA(a) Diparopsis B.28 CrylA(a) Tortrix spp.
castanea B.29 CrylA(a) Trichoplusia ni B.10 CrylA(a) Earias spp. B.30 CryIA(a) Agriotes spp.
B.11 CrylA(a) Ephestia spp. B.31 CrylA(a) Anthonomus B. 12 CryIA(a) Heliothis spp. grandis B.13 CrylA(a) Hellula undalis B.32 CrylA(a) Curculio spp.
B. 14 CryIA(a) Keiferia B.33 CryIA(a) Diabrotica balteata lycopersicella B.34 CrylA(a) Leptinotarsa spp.
B. 15 CryIA(a) Leucoptera scitella B.35 CrylA(a) Lissorhoptrus spp.
B. 16 CrylA(a) Lithocollethis spp. B.36 CrylA(a) Otiorhynchus spp.
B.17 CrylA(a) Lobesia botrana B.37 CrylA(a) Aleurothrixus spp.

AP Control of AP Control of B.38 CryIA(a) Aleyrodes spp. argillaceae B.39 CrylA(a) Aonidiella spp. B.69 CryiA(b) Anticarsia B.40 CrylA(a) Aphididae spp. gemmatalis B.41 CrylA(a) Aphis spp. B.70 CrytA(b) Chilo spp.
B.42 CryIA(a) Bemisia tabaci B.71 CrylA(b) Clysia ambiguella B.43 CryfA(s) Empoasca spp. B.72 CrylA(b) Crocidolomia B.44 CrylA(a) Mycus spp. binotalis B.45 CrylA(a) Nephotettix spp. B.73 CrylA(b) Cydia spp.
B.46 CrylA(a) Nitaparvata spp. B.74 CrylA(b) Diparopsis B.47 CrylA(a) Pseudococcus spp. castanea B.48 CryIA(a) Psytia spp. B.75 CrylA(b) Earias spp.
B.49 CryIA(a) Ouadraspidiotus B.76 CrylA(b) Ephestia spp.
spp. B.77 CryIA(b) Heliothis spp.
B.50 CrylA(a) Schizaphis spp. 1.78 CrylA(b) Hellula undalis B.51 CryIA(a) Trialeurodes spp. B.79 CrylA(b) Keiferia B.52 CrylA(a) Lyriomyza spp. lycopersicelia B.53 CrylA(a) Oscinelia spp. B.80 CrylA(b) Leucoptera scitella B.54 CrylA(a) Phorbia spp. B.81 CrylA(b) Lithocollethis spp.
B.55 CrylA(a) Frankliniella spp. B.82 CrylA(b) Lobesia botrana B.56 CrylA(a) Thrips spp. B.83 CrylA(b) Ostrinia nubilalis B.57 CrylA(a) Scirtothrips aurantii B.84 CrylA(b) Pandemis spp.
B.58 CryIA(a) Aceria spp. B.85 CrylA(b) Pectinophora B.59 CrylA(a) Aculus spp. gossyp.
B.60 CryIA(a) Brevipalpus spp. B.86 CrylA(b) Phyllocnistis citrella B.61 CrylA(a) Panonychus spp. B.87 CrylA(b) Pieris spp.
B.62 CryIA(a) Phyllocoptruta spp. B.88 CrylA(b) Plutelia xytostelia B.63 CrylA(a) Tetranychus spp. B.89 CrylA(b) Scirpophaga spp.
B.64 CrylA(a) Heterodera spp. B.90 CrylA(b) Sesamia spp.
B.65 CrylA(a) Meloidogyne spp. B.91 CrylA(b) Sparganothis spp.
B.66 CryIA(b) Adoxophyes spp. B.92 CrylA(b) Spodoptera spp.
B.67 CrylA(b) Agrotis spp. B.93 CrylA(b) Tortrix spp.
B.68 CrylA(b) Alabama B.94 CrylA(b) Trichoplusia ni WO 99/35913 pCT/EP99/00183 =65-AP Control of AP Control of B.95 CryIA(b) Agriotes spp. B.125 CryIA(b) Brevipalpus app.
B.96 CrylA(b) Anthonomus B.126 CrylA(b) Panonychus spp.
grandis B.127 CryIA(b) Phyllocoptruta spp.
B.97 CrylA(b) Curculio spp. B.128 CrylA(b) Tetranychus spp.
B.98 CrylA(b) Diabrotica balteata B.129 CrylA(b) Heterodera spp.
B.yy CrylA(b) Leptinolar.a spp. B.130 CryIA(b) Meloidogyne spF.
B.100 CrylA(b) Lissorhoptrus spp. B.131 CrylA(c) Adoxophyes spp.
B.101 CrylA(b) Otiorhynchus spp. B.132 CryIA(c) Agrotis spp.
B.102 CrylA(b) Aleurothrixus spp. B.133 CrylA(c) Alabama B.103 CryIA(b) Aleyrodes spp. argillaceae B. 104 CrylA(b) Aonidiella spp. B.134 CrylA(c) Anticarsia B. 105 CryIA(b) Aphididae spp. gemmatalis B.106 CryIA(b) Aphis spp. B.135 CryiA(c) Chilo spp.
B.107 CrylA(b) Bemisia tabaci B.136 CryIA(c) Clysia ambiguelia B.108 CrylA(b) Empoasca spp. B.137 CrylA(c) Crocidotomia B. 109 CrylA(b) Mycus spp. binotalis B.110 CrylA(b) Nephotettix spp. B.138 CryIA(c) Cydia spp.
B.l I 1 CrylA(b) Nilaparvata spp. B.139 CrylA(c) Diparopsis B.112 CrylA(b) Pseudococcus spp. castanea B.113 CrylA(b) Psylla spp. B.140 CrylA(c) Earias spp.
B.1 14 CrylA(b) Ouadraspidiotus B.141 CryIA(c) Ephestia spp.
spp, B.142 CrylA(c) Hetiothis spp.
B.115 CrylA(b) Schizaphis spp. B.143 CrylA(c) Helluia undalis B.116 CrylA(b) Trialeurodes spp. B.144 CrylA(c) Keiferia B.117 CrylA(b) Lyriomyza spp. lycopersicella B.1 18 CrylA(b) Oscinella spp. B.145 CryIA(c) Leucoptera scitelia B.119 CrylA(b) Phorbia spp. B.146 CryIA(c) Lithocollethis spp.
B.120 CrylA(b) Frankliniella spp. B.147 CryIA(c) Lobesia botrana B.121 CrytA(b) Thrips spp. B.148 CryIA(c) Ostrinia nubilalis B.122 CrylA(b) Scirtothrips aurantii B.149 CrylA(c) Pandemis spp.
B.123 CrylA(b) Aceria spp. B.150 CryIA(c) Pectinophora B.124 CrylA(b) Aculus spp. gossypiella.

AP Control of AP Control of B.151 CrylA(c) Phyllocnistts citrella B.181 CryIA(c) Trialeurodes spp.
B.152 Cry1A(c) Pieris spp. B.182 CryIA(c) Lyriomyza spp.
B.153 Cry1A(c) Plutelia xyiostella B.183 CryIA(c) Oscinelia spp.
B.154 CryIA(c) Scirpophaga spp. B.184 CryIA(c) Phorbia app.
B.155 CryIA(c) Sesamia spp. B.185 CryIA(c) Frankiiniella spp.
B.156 CryIA(c) BFaraarathis spp. B.186 CryIA(c) Thiips spp.
B.157 CryIA(c) Spodoptera spp. B.187 CryIA(c) Scirtothrips aurantii B.158 CrylA(c) Tortrix spp. B.188 CryIA(c) Aceria spp.
B.159 CrylA(c) Trichopiusia ni B.189 CryIA(c) Aculus spp.
B.160 CrylA(c) Agriotes spp. B.190 CryIA(c) Brevipalpus spp.
B.161 CryIA(c) Anthonomus B.191 CryIA(c) Panonychus spp.
grandis B.192 CrylA(c) Phyllocoptruta spp.
B.162 CrylA(c) Curculio spp. B.193 CryIA(c) Tetranychus app.
B.163 CrylA(c) Diabrotica balteata B.194 CrylA(c) Heterodera spp.
B.164 CryIA(c) Leptinotarsa spp. B.195 CryIA(c) Meloidogyne spp.
B.165 CryIA(c) Lissorhoptrus spp. B.196 CryIIA Adoxophyes spp.
B.166 CryIA(c) Otiorhynchus spp. B.197 CryIlA Agrotis spp.
B.167 CryIA(c) Aieurothrixus spp. B.198 CryliA Alabama B.168 CryIA(c) Aleyrodes spp. argiliaceae B.169 CryIA(c) Aonidiella spp. B.199 CryliA Anticarsia B.170 CryIA(c) Aphididae spp. gemmatalis B.171 CryIA(c) Aphis spp. B.200 Cry11A Chilo spp.
B.172 CryIA(c) Bemisia tabaci B.201 CryliA Clysia ambiguella B.173 CryIA(c) Empoasca spp. B.202 CryliA Crocidolomia B.174 Cry1A(c) Mycus spp. binotalis B.175 CryIA(c) Nephotettix spp. B.203 CryIlA Cydia spp.
B.176 CryIA(c) Nilaparvata spp. B.204 CryliA Diparopsis B.177 CryIA(c) Pseudococcus spp. castanea B.178 CryIA(c) Psylla spp. B.205 CryliA Earias spp.
B.179 CrylA(c) Quadraspidiotus B.206 CryliA Ephestia spp.
spp. B.207 CryliA Heliothis spp.
B.180 CryIA(c) Schizaphis spp. B.208 CryliA Heliula undalis AP Control of AP Control of B.209 CryilA Keiferia B.238 CryllA Empoasca spp.
lycopersicelia B.239 Cry11A Mycus spp.
B.210 CryliA Leucoptera scitella B.240 CryllA Nephotettix spp.
B.211 CryilA Uthocollethis spp. B.241 CryIIA Nilaparvata spp.
B.212 CryliA Lobesia botrana B.242 CryliA Pseudococcus spp.
a'13 CryIlA Ostrinia nublialis B.243 CryilA Psyila spp.
B.214 CryliA Pandemis spp. B.244 CryllA Quadraspidiotus B.215 CryliA Pectinophora sPP=
gossyp. B.245 CryllA Schizaphis spp.
B.216 CryliA Phyllocnistis citrella B.246 CryliA Trialeurodes spp.
B.217 CryliA Pieris spp. B.247 CryliA Lyriomyza spp.
B.218 CryliA Plutelia xylostelia B.248 CryllA Oscinella spp.
B.219 CryliA Scirpophaga spp. B.249 CryIIA Phorbia spp.
B.220 CryllA Sesamia spp. B.250 CryliA Frankliniella spp.
B.221 CryllA Sparganothis spp. B.251 CryliA Thrips spp.
B.222 CryliA Spodoptera spp. B.252 CryliA Scirtothrips aurantii B.223 CryllA Tortrix spp. B.253 CryliA Aceria spp.
B.224 CryllA Trichoplusia ni B.254 CryliA Aculus spp.
B.225 CryliA Agriotes spp. B.255 CryilA Brevipaipus spp.
B.226 CryllA Anthonomus B.256 CryliA Panonychus spp.
grandis B.257 CryllA Phyllocoptruta spp.
B.227 CryllA Curcufio spp. B.258 CryliA Tetranychus spp.
B.228 CryliA Diabrotica balteata B.259 CryllA Heterodera spp.
B.229 CryliA Leptinotarsa spp. B.260 CryliA Meloidogyne spp.
B.230 CryllA Lissorhoptrus spp. B.261 CryIlIA Adoxophyes app.
B.231 CryliA Otiorhynchus spp. B.262 CryIIIA Agrotis spp.
B.232 CryllA Aleurothrixus spp. B.263 CryIIIA Alabama B.233 CryliA Aleyrodes spp. argillaceae B.234 CryliA Aonidiella spp. B.264 CryIIlA Anticarsia B.235 CryliA Aphididae spp. gemmatalis B.236 CryliA Aphis spp. B.265 CrylilA Chilo spp.
B.237 CryliA Bemisia tabaci B.266 CryIIIA Clysia ambiguella AP Control of AP Control of B.267 Cryi11A Crocidolomia B.294 CryIIIA Leptinotansa spp.
binotalis B.295 Cry111A Lissorhoptrus spp.
B.268 Cry111A Cydia spp. B.296 CryIIIA Otiorhynchus spp.
B.269 CrylilA Diparopsis B.297 CryllIA Aleurothrixus spp.
castanea B.298 CryllIA Aleyrodes spp.
B.270 CryIIIA Earias spp. B.299 CrylliA Aonidiefia spp.
B.271 CrylliA Ephestia spp. B.300 Cry111A Aphididae spp.
B.272 CryllIA Heliothis spp. B.301 CrylliA Aphis spp.
B.273 CryllIA Hellula undalis B.302 CryI11A Bemisia tabaci B.274 CryllIA Keiferia B.303 Cry111A Empoasca spp.
lycopersicella B.304 CryllIA Mycus spp.
B.275 CryllIA Leucoptera scitella B.305 CryIIIA Nephotettix spp.
B.276 CryIIIA Lithocollethis spp. B.306 CrylilA Nilaparvata spp.
B.277 CryllIA Lobesia botrana B.307 CrylliA Pseudococcus spp.
B.278 CrylliA Ostrinia nubilalis B.308 CryllIA Psylla spp.
B.279 CryllIA Pandemis spp. B.309 CryllIA Quadraspidiotus B.280 CrylliA Pectinophora spp.
gossyp. B.310 CryllIA Schizaphis spp.
B.281 CryllIA Phyllocnistis citrella B.311 CryllIA Trialeurodes spp.
B.282 CryI11A Pieris spp. B.312 Cry111A Lyriomyza spp.
B.283 CryllIA Plutelia xylostelia B.313 CryillA Oscinella spp.
B.284 Cryl11A Scirpophaga spp. B.314 Cry111A Phorbia spp.
B.285 CryllIA Sesamia spp. B.315 CryllIA Frankliniella spp.
B.286 CryllIA Sparganothis spp. B.316 CrylliA Thrips spp.
B.287 CryllIA Spodoptera spp. B.317 CryIIIA Scirtothrips aurantii R.288 CryIIIA Tortrix spp. B.318 Cry111A Aceria spp.
B.289 CrylliA Trichoplusia ni B.319 CryllIA Aculus spp.
B.290 CryllIA Agriotes spp. B.320 CrylliA Brevipalpus spp.
B.291 CryIIIA Anthonomus B.321 CrylllA Panonychus spp.
grandis B.322 Cry111A Phyllocoptruta spp.
B.292 CryllIA Curculio spp. ' B.323 CryIIIA Tetranychus spp.
B.293 CryllIA Diabrotica balteata B.324 CrylliA Heterodera spp.

AP Control of AP Control of B.325 CryIIIA Meloidogyne spp. B.351 CrylllB2 Sparganothis spp.
B.326 CrylllB2 Adoxophyes spp. B.352 CrylllB2 Spodoptera spp.
B.327 CrylllB2 Agrotis spp. B.353 CrylllB2 Tortrix app.
B.328 CrylllB2 Alabama B.354 CrylIIB2 Trichoplusia ni argiliaceae B.355 CrylllB2 Agriotes spp.
b.;2y CrylllB2 Anticarsia B.356 f.,ry!tlB2 Anthonomus gemmatalis grandis B.330 CrylllB2 Chilo spp. B.357 CryI11B2 Curculio spp.
B.331 CrylllB2 Clysia ambiguella B.358 CrylllB2 Diabrotica balteata B.332 CryIilB2 Crocidolomia B.359 CrylIlB2 Leptinotarsa spp.
binotalis B.360 CryIiIB2 Lissorhoptrus spp.
B.333 CrylllB2 Cydia spp. B.361 CrylllB2 Otiorhynchus spp.
B.334 CrylllB2 Diparopsis B.362 CrylllB2 Aieurothrixus spp.
castanea B.363 CrylllB2 Aleyrodes spp.
B.335 CrylllB2 Earias spp. B.364 CrylllB2 Aonidielia spp.
B.336 CryIlIB2 Ephestia spp. B.365 CrylllB2 Aphididae spp.
B.337 CryIlIB2 Heliothis spp. B.366 CryI11B2 Aphis spp.
B.338 CrylllB2 Helluia undalis B.367 CrylI1B2 Bemisia tabaci B.339 CrylllB2 Keiferia B.368 CrylllB2 Empoasca spp.
iycopersicelia B.369 CrylllB2 Mycus spp.
B.340 CrylllB2 Leucoptera scitelia B.370 CrylllB2 Nephotettix spp.
B.341 CryllIB2 Lithocollethis spp. B.371 CrylllB2 Nilaparvata spp.
B.342 CrylIIB22 Lobesia botrana B.372 CryIIIB2 Pseudococcus spp.
B.343 CryII1B2 Ostrinia nubilalis B.373 CrylI1B2 Psylla spp.
B.344 CrylllB2 Pandemis spp. B.374 CrylllB2 Quadraspidiotus B.345 CrylllB2 Pectinophora spp.
gossyp. B.375 CrylI1B2 Schizaphis spp.
B.346 CrylllB2 Phyliocnistis citrella B.376 CrylllB2 Trialeurodes spp.
B.347 CrylllB2 Pieris spp. B.377 CryilIB2 Lyriomyza spp.
B.348 CrylllB2 Plutelia xytostella B.378 CrylllB2 Oscinelia spp.
B.349 CrylllB2 Scirpophaga spp. B.379 CrylliB2 Phorbia spp.
B.350 CrylllB2 Sesamia spp. B.380 CrylllB2 Franklinielia spp.

AP Control of AP Control of B.381 CryllIB2 Thrips spp. B.408 CytA Ostrinia nubilalis B.382 CryII1B2 Scirtothrips aurantii B.409 CytA Pandemis spp.
B.383 CrylllB2 Aceria spp. B.410 CytA Pecbnophora B.384 CryllIB2 Aculus spp. gossyp=
B.385 CryllIB2 Brevipalpus spp. B.411 CytA Phyllocnistis citrelia n.3o6 Cry=111B2 Panonychus spp. B.412 CyA Pieris app.
B.387 CryllIB2 Phyllocoptruta spp. B.413 CytA Plutella xyiostella B.388 CrylllB2 Tetranychus spp. B.414 CytA Scirpophaga spp.
B.389 CryllIB2 Heterodera spp. B.415 CytA Sesamia spp.
B.390 CryllIB2 Meloidogyne spp. B.416 CytA Sparganothis spp.
B.391 CytA Adoxophyes spp. B.417 CytA Spodoptera spp.
B.392 CytA Agrotis spp. B.418 CytA Tortrix spp.
B.393 CytA Alabama B.419 CytA Trichoplusia ni argillaceae B.420 CytA Agriotes spp.
B.394 CytA Anticarsia B.421 CytA Anthonomus gemmatalis grandis B.395 CytA Chilo spp. B.422 CytA Curculio spp.
B.396 CytA Clysia ambiguella B.423 CytA Diabrotica balteata B.397 CytA Crocidolomia B.424 CytA Leptinotarsa spp.
binotalis B.425 CytA Lissorhoptrus spp.
B.398 CytA Cydia spp. B.426 CytA Otiorhynchus spp.
B.399 CytA Diparopsis B.427 CytA Aleurothrixus spp.
castanea B.428 CytA Aleyrodes spp.
B.400 CytA Earias spp. B.429 CytA Aonidielia spp.
B.401 CytA Ephestia spp. B.430 CytA Aphididae spp.
B.402 CytA Heliothis spp. B.431 CytA Aphis spp.
B.403 CytA Hellula undalis B.432 CytA Bemisia tabaci B.404 CytA Keiferia B.433 CytA Empoasca spp.
lycopersicella B.434 CytA Mycus spp.
B.405 CytA Leucoptera scitella B.435 CytA Nephotetltx spp.
B.406 CytA Lithocollethis spp. B.436 CytA Nilaparvata spp.
B.407 CytA Lobesia botrana B.437 CytA Pseudococcus spp.

WO 99/35913 PCT EP"/00183 AP Control of AP Control of B.438 CytA Psylla spp. B.465 VIP3 Earias spp.
B.439 CYtA Quadraspidiotus B.466 VIP3 Ephestia spp.
$pp. B.467 VIP3 Heliothis spp.
B.440 CytA Schizaphis spp. B.468 VIP3 Hellula undalis B.441 CytA Trialeurodes spp. B.469 VIP3 Keiferia B.442 CytA Lyriomyza spp. -ycopers:celle B.443 CytA Oscinella spp. B.470 VIP3, Leucoptera scitella B.444 CytA Phorbia spp. B.471 VIP3 Lithocollethis app.
B.445 CytA Franktiniella spp. B.472 VIP3 Lobesia botrana B.446 CytA Thrips spp. B.473 VIP3 Ostrinia nubiiafis B.447 CytA Scirtothrips aurantii B.474 VIP3 Pandemis spp.
B.448 CytA Aceria spp. B.475 VIP3 Pectinophora B.449 CytA Aculus spp. gossyp.
B.450 CytA Brevipalpus spp. B.476 VIP3 Phyllocnistis citrella B.451 CytA Panonychus spp. B.477 VIP3 Pieris spp.
B.452 CytA Phyllocoptruta spp. B.478 VIP3 Plutelia xylostella B.453 CytA Tetranychus app. B.479 VIP3 Scirpophaga spp.
B.454 CytA Heterodera spp. B.480 VIP3 Sesamia app.
B.455 CytA Meloidogyne spp. B.481 VIP3 Sparganothis spp.
B.456 VIP3 Adoxophyes spp. B.482 VIP3 Spodoptera spp.
B.457 VIP3 Agrotis spp. B.483 VIP3 Tortrix spp.
B.458 VIP3 Alabama B.484 VIP3 Trichoplusia ni argillaceae B.485 VIP3 Agriotes spp.
B.459 VIP3 Anticarsia B.486 VIP3 Anthonomus gemmataiis grandis B.460 VIP3 Chilo spp. B.487 VIP3 Curculio spp.
B.461 VIP3 Clysia ambiguella B.488 VIP3 Diabrotica batteata B.462 VIP3 Crocidolomia B.489 VIP3 Leptinotarsa spp.
binotalis B.490 VIP3 Lissorhoptrus spp.
B.463 VIP3 Cydia spp. B.491 VIP3 Otiorhynchus spp.
B.464 VIP3 Diparopsis B.492 VIP3 Aleurothrixus spp.
castanea B.493 VIP3 Aleyrodes epp.

=72i AP Control of AP Control of B.494 VIP3 Aonidielia spp. B.524 GL Anticarsia B.495 VIP3 Aphididae spp. gemmatalis B.496 VIP3 Aphis spp. B.525 GL Chilo spp.
B.497 VIP3 Bemisia tabaci B.526 GL Clysia ambiguella B.498 VIP3 Empoasca app. B.527 GL Crocidolomia B.499 VIP3 Mycus spp. binotatis B.500 VIP3 Nephotettix spp. B.528 GL Cydia spp.
B.501 VIP3 Nilaparvata spp. B.529 GL Diparopsis B.502 VIP3 Pseudococcus spp. castanea B.503 VIP3 Psylla spp. B.530 GL Earias spp.
B.504 VIP3 Ouadraspidiotus B.531 GL Ephestia spp.
spp. B.532 GL Heliothis spp.
B.505 VIP3 Schizaphis spp. B.533 GL Hellula undalis B.506 VIP3 Trialeurodes spp. B.534 GL Keiferia B.507 VIP3 Lyriomyza spp. lycopersicelia B.508 VIP3 Oscinella spp. B.535 GL Leucoptera scitelia B.509 VIP3 Phorbia spp. B.536 GL Lithocollethis app.
B.510 VIP3 Franklinieila spp. B.537 GL Lobesia botrana B.511 VIP3 Thrips spp. B.538 GL Ostrinia nubilalis B.512 VIP3 Scirtothrips aurantii B.539 GL Pandemis spp.
B.513 VIP3 Aceria spp. B.540 GL Pectinophora B.514 VIP3 Aculus spp. gossyp.
B.515 VIP3 Brevipaipus spp. B.541 GL Phyllocnistis citrelia B.516 VIP3 Panonychus spp. B.542 GL Pieris spp.
B.517 VIP3 Phyllocoptruta spp. B.543 GL Plutelia xylostella B.518 VIP3 Tetr=anychus spp. B.544 GL Scirpophaga spp.
B.519 VIP3 Heterodera spp. B.545 GL Sesamia spp.
B.520 VIP3 Meloidogyne spp. B.546 GL Sparganothis spp.
B.521 GL Adoxophyes spp. B.547 GL Spodoptera spp.
B.522 GL Agrotis spp. B.548 GL Tortrix spp.
B.523 GL Alabama B.549 GL Trichoplusia ni argillaceae B.550 GL Agriotes spp.

AP Control of AP Control of B.551 GL Anthonomus B.581 GL Panonychus spp.
grandis B.582 GL Phyllocoptruta spp.
B.552 GL Curculio spp. B.583 GL Tetranychus spp.
B.553 GL Diabrotica balteata B.584 GL Heterodera spp.
B.554 GL Leptinotarsa spp. B.585 GL Meloidogyne spp.
;.555 GL Lissorhoptrus spp. B.586 PL Acbxophyes spp.
B.556 GL Otiorhynchus spp. B.587 PL Agrotis spp.
B.557 GL Aleurothrixus spp. B.588 PL Alabama B.558 GL Aleyrodes spp. argillaceae B.559 GL Aonidiella spp. B.589 PL Anticarsia B.560 GL Aphididae spp. gemmatalis B.561 GL Aphis spp. B.590 PL Chilo spp.
B.562 GL Bemisia tabaci B.591 PL Clysia ambiguelia B.563 GL Empoasca spp. B.592 PL Crocidolomia B.564 GL Mycus spp. binotalis B.565 GL Nephotettix spp. B.593 PL Cydia spp.
B.566 GL Nilaparvata spp. B.594 PL Diparopsis B.567 GL Pseudococcus spp. castanea B.568 GL Psylla spp. B.595 PL Earias spp.
B.569 GL Quadraspidiotus B.596 PL Ephestia spp.
spp. B.597 PL Heliothis spp.
B.570 GL Schizaphis spp. B.598 PL Hellula undalis B.571 GL Trialeurodes spp. B.599 PL Keiferia B.572 GL Lyriomyza spp. lycopersicella B.573 GL Oscinelia spp. B.600 PL Leucoptera scitella B.574 GL Phorbia spp. B.601 PL Lithocollethis spp.
B.575 GL Frankliniella spp. B.602 PL Lobesia botrana B.576 GL Thrips spp. B.603 PL Ostrinia nubilalis B.577 GL Scirtothrips aurantii B.604 PL Pandemis spp.
B.578 GL Aceria spp. B.605 PL Pectinophora B.579 GL Aculus spp. gossyp.
B.580 GL Brevipalpus spp. B.606 PL Phyllocnistis citrella AP Control of AP Control of B.607 PL Pieris app. B.637 PL Lyriomyza spp.
B.608 PL Plutella xylostella B.638 PL Oscinella spp.
B.609 PL Scirpophaga spp. B.639 PL Phorbia spp.
B.610 PL Sesamia spp. B.640 PL Frankliniella spp.
B.611 PL Sparganothis spp. B.641 PL Thrips spp.
B.612 PL Spodoptera sFp. B.642 PL Srirtothrips aurantii B.613 PL Tortrix spp. B.643 PL Aceria spp.
B.614 PL Trichoplusia ni B.644 PL Aculus spp.
B.615 PL Agrlotes spp. B.645 PL Brevipaipus spp.
B.616 PL Anthonomus B.646 PL Panonychus spp.
grandis B.647 PL Phyllocoptruta spp.
B.617 PL Curculio spp. B.648 PL Tetranychus spp.
B.618 PL Diabrotica balteata B.649 PL Heterodera spp.
B.619 PL Leptinotarsa spp. B.650 PL Meloidogyne spp.
B.620 PL Lissorhoptrus spp. B.651 XN Adoxophyes spp.
B.621 PL Otiorhynchus spp. B.652 XN Agrotis spp.
B.622 PL Aleurothrixus spp. B.653 XN Alabama B.623 PL Aleyrodes spp. argillaceae B.624 PL Aonidiella spp. B.654 XN Anticarsia B.625 PL Aphididae spp. gemmatalis B.626 PL Aphis spp. B.655 XN Chilo spp.
B.627 PL Bemisia tabaci B.656 XN Clysia ambiguella B.628 PL Empoasca spp. B.657 XN Crocidolomia B.629 PL Mycus spp. binotalis B.630 PL Nephotettix spp. B.658 XN Cydia spp.
B.631 PL Nilaparvata spp. B.659 XN Diparopsis B.632 PL Pseudococcus spp. castanea B.633 PL Psylla.spp. B.660 XN Earias spp.
B.634 PL Quadraspidiotus B.661 XN Ephestia spp.
spp. B.662 XN Heliothis spp.
B.635 PL Schizaphis spp. B.663 XN Hellula undalis B.636 PL Trialeurodes spp. B.664 XN Keiferia AP Control of AP Control of lycopersicella B.694 XN IVlycus spp.
B.665 XN Leucoptera scitelia B.695 XN Nephotettix spp.
B.666 XN Lithocollethis spp. B.696 XN Nilapanrata spp.
B.667 XN Lobesia botrana B.697 XN Pseudococcus spp.
B.668 XN Ostrinia nubilalis B.698 XN Psylla spp.
B.6i~9 XN Pandemis spp. B.699 XN Quadraspidiotus B.670 XN Pectinophora spp.
gossyp. B.700 XN Schizaphis spp.
B.671 XN Phyllocnistis citrella B.701 XN Trialeurodes spp.
B.672 XN Pieris spp. B.702 XN Lyriomyza spp.
B.673 XN Plutella xyiostelia B.703 XN Oscinella spp.
B.674 XN Scirpophaga spp. B.704 XN Phorbia spp.
B.675 XN Sesamia spp. B.705 XN Frankliniella spp.
B.676 XN Sparganothis spp. B.706 XN Thrips spp.
B.677 XN Spodoptera spp. B.707 XN Scirtothrips aurantii B.678 XN Tortrix spp. B.708 XN Aceria spp.
B.679 XN Trichoplusia ni B.709 XN Aculus spp.
B.680 XN Agriotes spp. B.710 XN Brevipaipus spp.
B.681 XN Anthonomus B.71 l XN Panonychus spp.
grandis B.712 XN Phyllocoptruta spp.
B.682 XN Curculio spp. B.713 XN Tetranychus spp.
B.683 XN Diabrotica balteata B.714 XN Heterodera spp.
B.684 XN Leptinotarsa spp. B.715 XN Meloidogyne spp.
B.685 XN Lissorhoptrus spp. B.716 Plnh. Adoxophyes spp.
B.686 XN Otiorhynchus spp. B.717 Pinh. Agrotis spp.
B.687 XN Aleurothrixus spp. B.718 Plnh. Alabama B.688 XN Aleyrodes spp. argillaceae B.689 XN Aonidiefia spp. B.719 Pinh. Anticarsia B.690 XN Aphididae spp. gemmatalis B.691 XN Aphis spp. B.720 Ptnh. Chilo spp.
B.692 XN Bemisia tabaci B.721 Pinh. Clysia ambiguella B.693 XN Empoasca spp. B.722 Plnh. Crocidolomia AP Control of AP Control of binotalis B.750 Plnh. Lissorhoptrus spp.
B.723 Plnh. Cydia spp. B.751 Pinh. Otiorhynchus spp.
B.724 Plnh. Diparopsis B.752 Pinh. Aleurothrixus spp.
castanea B.753 Pinh. Aleyrodes spp.
B.725 Pinh. Earias spp. B.754 Plnh. Aonidiella spp.
B.726 Pinh. Ephestia spp. B.755 Plnh. Aphididae spp.
B.727 Plnh. Heliothis spp. B.756 Pinh. Aphis spp.
B.728 Plnh. Hellula undalis B.757 Plnh. Bemisia tabaci B.729 Pinh. Keiferia B.758 Pinh. Empoasca spp.
lycopersicella B.759 Pinh. Mycus spp.
B.730 Pinh. Leucoptera scitella B.760 Pinh. Nephotettix spp.
B.731 Pinh. Lithocollethis spp. B.761 Pinh. Nilaparvata spp.
B.732 Plnh. Lobesia botrana B.762 Plnh. Pseudococcus spp.
B.733 Pinh. Ostrinia nubilalis B.763 Plnh. Psylla spp.
B.734 Pinh. Pandemis spp. B.764 Plnh. Quadraspidiotus B.735 Plnh. Pectinophora spP.
gossyp. B.765 Plnh. Schizaphis spp.
B.736 Pinh. Phyitocnistis citrella B.766 Pinh. Trialeurodes spp.
B.737 Plnh. Pieris spp. B.767 Plnh. Lyriomyza spp.
B.738 Pinh. Plutella xylostella B.768 Plnh. Oscinelia spp.
B.739 Plnh. Scirpophaga spp. B.769 Plnh. Phorbia spp.
B.740 Plnh. SeSamia spp. B.770 Plnh. Frankfiniella spp.
B.741 Pinh. Sparganothis spp. B.771 Pinh. Thrips spp.
B.742 Pinh. Spodoptera spp. B.772 Plnh. Scirtothrips aurantii B.743 Pinh. Tortrix spp. B.773 Plnh. Aceria spp.
B.744 Plnh. Trichoplusia ni B.774 Plnh. Aculus spp.
B.745 Plnh. Agriotes spp. B.775 Plnh. Brevipaipus spp.
B.746 Pinh. Anthonomus B.776 Pinh. Panonychus spp.
grandis B.777 Pinh. Phyllocoptruta spp.
B.747 Pinh. Curculio spp. B.778 Pinh. Tetranychus spp.
B.748 Pinh. Diabrotica balteata B.779 Pinh. Heterodera spp.
B.749 Pinh. Leptinotarsa spp. B.780 Pinh. Meloidogyne spp.

-n-AP Control of AP Control of B.781 PLec. Adoxophyes spp. B.807 PLec. Spodoptera spp.
B.782 PLec. Agrotis spp. B.808 PLec. Tortrix spp.
B.783 PLec. Alabama B.809 PLec. Trichoplusia ni argillaceae B.810 PLec. Agriotes spp.
B.784 PLec. Anticarsia B.811 PLec. Anthonomus gemmatalis gmndis B.785 PLec. Chito spp. B.812 PLec. Curculio spp.
B.786 PLec. Clysia ambiguella B.813 PLec. Diabrotica balteata B.787 PLec. Crocidolomia B.814 PLec. Leptinotarsa spp.
binotalis B.815 PLec. Lissorhoptrus spp.
B.788 PLec. Cydia spp. B.816 PLec. Otiorhynchus spp.
B.789 PLec. Diparopsis B.817 PLec. Aleurothrixus spp.
castanea B.818 PLec. Aleyrodes spp.
B.790 PLec. Earias spp. B.819 PLec. Aonidielia spp.
B.791 PLec. Ephestia spp. B.820 PLec. Aphididae spp.
B.792 PLec. Heliothis spp. B.821 PLec. Aphis spp.
B.793 PLec. Hellula undalis B.822 PLec. Bemisia tabaci B.794 PLec. Keiferia B.823 PLec. Empoasca spp.
lycopersicelia B.824 PLec. Mycus spp.
B.795 PLec. Leucoptera scitelia B.825 PLec. Nephotettix spp.
B.796 PLec. Lithocollethis spp. B.826 PLec. Nilaparvata spp.
B.797 PLec. Lobesia botrana B.827 PLec. Pseudococcus spp.
B.798 PLec. Ostrinia nubilalis B.828 PLec. Psylia spp.
B.799 PLec. Pandemis spp. B.829 PLec. Ouadraspidiotus B.800 PLec. Pectinophora sPP=
gossyp. B.830 PLec. Schizaphis spp.
B.801 PLec. Phyllocnistis citrella B.831 PLec. Trialeurodes spp.
B.802 PLec. Pieris spp. B.832 PLec. Lyriomyza spp.
B.803 PLec. Plutetla xylosteQa B.833 PLec. Oscinelia spp.
B.804 PLec. Scirpophaga spp. B.834 PLec. Phorbia spp.
B.805 PLec. Sesamia spp. B.835 PLec. Franklinielia spp.
B.806 PLec. Sparganothis spp. B.836 PLec. Thrips spp.

AP Controi of AP Control of B.837 PLec. Scirtothrips aurantii B.864 Aggi. Pandemis spp.
B.838 PLec. Aceria spp. B.865 Aggl. Pecqnophora B.839 PLec. Aculus spp. gossyp-B.840 PLec. Brevipalpus spp. B.866 Aggl. Phyllocnistis citrelia B.841 PLec. Panonychus spp. B.867 Aggl. Pieris spp.
B.842 PLec. PhyNo%-.ptruta spr. B.868 Aggi. Pluteiis xylostelia B.843 PLec. Tetranychus spp. B.869 Aggi. Scirpophaga spp.
B.844 PLec. Heterodera spp. B.870 Aggi. Sesamia spp.
B.845 PLec. Meloidogyne spp. B.871 Aggi. Sparganothis spp.
B.846 Aggi. Adoxophyes spp. B.872 Aggi. Spodoptera spp.
B.847 Aggi. Agrotis spp. B.873 Aggi. Tortrix spp.
B.848 Aggl. Alabama B.874 Aggi. Trichoplusia ni argillaceae B.875 Aggi. Agriotes spp.
B.849 Aggl. Anticarsia B.876 Aggi. Anthonomus gemmatalis grandis B.850 Aggl. Chilo spp. B.877 Aggi. Curcuiio spp.
B.851 Aggl. Clysia ambiguella B.878 Aggi. Diabrotica balteata B.852 Aggi. Crocidolomia B.879 Aggl. Leptinotarsa spp.
binotalis B.880 Aggi. Lissorhoptrus spp.
B.853 Aggi. Cydia spp. B.881 Aggi. Otiorhynchus spp.
B.854 Aggi. Diparopsis B.882 Aggl. Aleurothrixus spp.
castanea B.883 Aggi. Aleyrodes spp.
B.855 Aggi. Earias spp. B.884 Aggi. Aonidielia spp.
B.856 Aggi. Ephestia spp. B.885 Aggl. Aphididae spp.
B.857 Aggi. Hetiothis spp. B.886 Aggi. Aphis spp.
B.858 Aggl. Hellula undalis B.887 Aggi. Bemisia tabaci B.859 Aggi. Keiferia B.888 Aggi. Empoasca spp.
lycopersicella B.889 Aggi. Mycus spp.
B.860 Aggi. Leucoptera scitella B.890 Aggi. Nephotettix spp.
B.861 Aggi. Lithocollethis spp. B.891 Aggi. Nilaparvata spp.
B.862 Aggl. Lobesia botrana B.892 Aggi. Pseudococcus spp.
B.863 Aggi. Ostrinia nubilalis B.893 Aggi. Psyfia spp.

AP Control of AP Control of B.894 Aggi. C.luadraspidiotus B.921 CO Ephestia spp.
spp. B.922 CO Heliothis spp.
B.895 Aggi. Schizaphis spp. B.923 CO Hellula undalis B.896 Aggl. Trialeurodes spp. B.924 CO Ke'rferia B.897 Aggi. Lyriomyza app. iycopen3icelia B.898 ' Aggi. Oscinella app. B.925 CO Leucoptera scitella B.899 Aggl. Phorbia spp. B.926 CO Lithocollethis spp.
B.900 Aggl. Frankliniella spp. B.927 CO Lobesia botrana B.901 Aggl. Thrips spp. B.928 CO Ostrinia nubilalis B.902 Aggl. Scirtothrips aurantii B.929 CO Pandemis spp.
B.903 Aggi. Aceria spp. B.930 CO Pectinophora B.904 Aggi. Aculus spp. gossyp.
B.905 Aggl. Brevipatpus spp. B.931 CO Phyllocnistis citrella B.906 Aggt. Panonychus spp. B.932 CO Pieris spp.
B.907 Aggi. Phyllocoptruta spp. B.933 CO Plutella xylostelia B.908 Aggl. Tetranychus spp. B.934 CO Scirpophaga spp.
B.909 Aggl. Heterodera spp. B.935 CO Sesamia spp.
B.910 Aggl. Meloidogyne spp. B.936 CO Sparganothis spp.
B.911 CO Adoxophyes spp. B.937 CO Spodoptera spp.
B.912 CO Agrotis spp. B.938 CO Tortrix spp.
B.913 CO Alabama B.939 CO Trichoplusia ni argillaceae B.940 CO Agriotes spp.
B.914 CO Anticarsia B.941 CO Anthonomus gemmatalis grandis B.915 CO Chilo spp. B.942 CO Curculio spp.
B.916 CO Clysia ambiguelia B.943 CO Diabrotica balteata B.917 CO Crocidolomia B.944 CO Leptinotarsa spp.
binotalis B.945 CO Lissorhoptrus spp.
B.918 CO Cydia spp. B.946 CO Otiorhynchus spp.
B.919 CO Diparopsis B.947 CO Aleurothrixus spp.
castanea B.948 CO Aleyrodes spp.
B.920 CO Earias spp. B.949 CO Aonidiella spp.

AP Control of AP Control of B.950 CO Aphididae spp. gemmataiis B.951 CO Aphis spp. B.980 CH Chilo spp.
B.952 CO Bemisia tabaci B.981 CH Clysia ambiguella B.953 CO Empoasca spp. B.982 CH Crocidolomia B.954 CO Mycus spp. binotalis B.955 CO NephotettiX spp. B.983 CH Cydia spp.
B.956 CO Nilaparvata spp. B.984 CH Diparopsis B.957 CO Pseudococcus spp. castanea B.958 CO Psylia spp. B.985 CH Earias spp.
B.959 CO Quadraspidiotus B.986 CH Ephestia spp.
spp. B.987 CH Heliothis spp.
B.960 CO Schizaphis spp. B.988 CH Helluia undalis B.961 CO Trialeurodes spp. B.989 CH Keiferia B.962 CO Lyriomyza spp. iycopersicella B.963 CO Oscinella spp. B.990 CH Leucoptera scitelia B.964 CO Phorbia spp. B.991 CH LithocoUethis spp.
B.965 CO Franklinielia spp. B.992 CH Lobesia botrana B.966 CO Thrips spp. B.993 CH Ostrinia nubilaiis B.967 CO Scirtothrips aurantii B.994 CH Pandemis spp.
B.968 CO Aceria spp. B.995 CH Pectinophora B.969 CO Aculus spp. gossyp.
B.970 CO Brevipalpus spp. B.996 CH Phyllocnistis citrelia B.971 CO Panonychus spp. B.997 CH Pieris spp.
B.972 CO Phyllocoptruta spp. B.998 CH Plutella xylostella B.973 CO Tetranychus spp. B.999 CH Scirpophaga spp.
B.974 CO Heterodera spp. B.1000 CH Sesamia spp.
B.975 CO Meloidogyne spp. B.1001 CH Sparganothis spp.
B.976 CH Adoxophyes spp. B.1002 CH Spodoptera spp.
B.977 CH Agrotis spp. B.1003 CH Tortrix spp.
B.978 CH Alabama B.1004 CH Trichoplusia ni argillaceae B.1005 CH Agriotes spp.
B.979 CH Anticarsia B.1006 CH Anthonomus . g~ .

AP Control of AP Control of grandis B.1037 CH Phyllocoptruta spp.
B.1007 CH Curculio spp. B.1038 CH Tetranychus spp.
B.1008 CH Diabrotica balteata B.1039 CH Heterodera spp.
B.1009 CH Leptinotarsa spp. B.1040 CH Meloidogyne spp.
B.1010 CH Lissorhoptrus spp. B.1041 SS Adoxophyes spp.
B.1011 CH Otiorhynohus app. B.1042 SS Agrotis spp.
B.1012 CH Aleurothrixus spp. B. 1043 SS Alabama B.1013 CH Aleyrodes spp. argillaceae B.1014 CH Aonidielia spp. B.1044 SS Anticarsia B.1015 CH Aphididae spp. gemmatalis B.1016 CH Aphis spp. B.1045 SS Chilo spp.
B.1017 CH Bemisia tabaci B.1046 SS Clysia ambiguella B.1018 CH Empoasca spp. B.1047 SS Crocidolomia B.1019 CH Mycus spp. binotalis B.1020 CH Nephotettix spp. B.1048 SS Cydia spp.
B.1021 CH Nilaparvata spp. B.1049 SS Diparopsis B.1022 CH Pseudococcus spp. castanea B.1023 CH Psylla spp. B.1050 SS Earias spp.
B.1024 CH Quadraspidiotus B.1051 SS Ephestia spp.
spp. B.1052 SS Heliothis spp.
B.1025 CH Schizaphis spp. B.1053 SS Hellula undalis B.1026 CH Trialeurodes spp. B.1054 SS Keiferia B.1027 CH Lyriomyza spp. lycopersicella B.1028 CH Oscinella spp. B.1055 SS Leucoptera scitella B.1029 CH Phorbia spp. B.1056 SS Lithocollethis spp.
B.1030 CH Franklinielia spp. B.1057 SS Lobesia botrana B. 1031 CH Thrips spp. B.1058 SS Ostrinia nubilalis B.1032 CH Scirtothrips aurantii B.1059 SS Pandemis spp.
B.1033 CH Aceria spp. B.1060 SS Pectinophora B.1034 CH Aculus spp. gossyp.
B.1035 CH Brevipatpus spp. B.1061 SS Phyllocnistis citrelia B.1036 CH Panonychus spp. B.1062 SS Pieris spp.

WO 99/35913 P~~~~193 AP Control of AP Control of B.1063 SS Plutelia xylosteiia B.1093 SS Oscinelia spp.
B.1064 SS Scirpophaga spp. B.1094 SS Phorbia spp.
B.1065 SS Sesamia spp. B.1095 SS Franklinielia spp.
B.1066 SS Sparganothis spp. B.1096 SS Thrips spp.
B.1067 SS Spodoptera spp. B. 1097 SS Scirtothrips aurantii B.1068 SS Tortrix spp. B.1093 SS ~ Aceria spp.
B.1069 SS Trichopiusia ni B.1099 SS Aculus spp.
B.1070 SS Agriotes spp. B. 1100 SS Brevipaipus spp.
B.1071 SS Anthonomus B.1101 SS Panonychus spp.
grandis B.1102 SS Phyllocoptruta spp.
B.1072 SS Curculio spp. B.1103 SS Tetranychus spp.
B.1073 SS Diabrotica balteata B.1104 SS Heterodera spp.
B.1074 SS Leptinotarsa spp. B.1105 SS Meloidogyne spp.
B.1075 SS Lissorhoptrus spp. B.1106 HO Adoxophyes spp.
B.1076 SS Otiorhynchus spp. B.1107 HO Agrotis spp.
B.1077 SS Aleurothrixus spp. B.1108 HO Alabama B.1078 SS Aleyrodes spp. argillaceae B.1079 SS Aonidielia spp. B. 1109 HO Anticarsia B. 1080 SS Aphididae spp. gemmatalis B.1081 SS Aphis spp. B.1110 HO Chilo spp.
B.1082 SS Bemisia tabaci B.1111 HO Clysia ambiguella B.1083 SS Empoasca spp. B.1112 HO Crocidolomia B.1084 SS Mycus spp. binotalis B. 1085 SS Nephotettix spp. B.1113 HO Cydia spp.
B.1086 SS Nilaparvata spp. B.1114 HO Diparopsis B. 1087 SS Pseudococcus spp. castanea B.1088 SS Psylla spp. B.1115 HO Eartas spp.
B.1089 SS Gluadraspidiotus B.1116 HO Ephestia spp.
spp. B.1117 HO Heliothis spp.
B.1090 SS Schizaphis spp. B.1118 HO Hellula undalis B.1091 SS Trialeurodes spp. B.1119 HO Keiferia B.1092 SS Lyriomyza spp. iycopersicella AP Control of AP Control of B.1120 HO Leucoptera scitella B.1145 HO Aphididae spp.
B.1121 HO Lithocollethis spp. B.1146 HO Aphis spp.
B.1122 HO Lobesia botrana B.1147 HO Bemisia tabaci B.1123 HO Ostrinia nubilalis B.1148 HO Empoasca spp.
B.1124 HO Pandemis spp. B.1149 HO Mycus spp.
B.1125 HO Pectinophora B. 1150 HO Nephotettix spp.
gossypiella B.1151 HO Nilaparvata spp.
B.1126 HO Phyllocnistis citrella B. 1152 HO Pseudococcus spp.
B.1127 HO Pieris spp. B.1153 HO Psylia spp.
B. 1128 HO Plutella xylostella B.1154 HO Quadraspidiotus B.1129 HO Scirpophaga spp. spp.
B.1130 HO Sesamia spp. B.1155 HO Schizaphis spp.
B.1131 HO Sparganothis spp. B.1156 HO Trialeurodes spp.
B.1132 HO Spodoptera spp. B.1157 HO Lyriomyza spp.
B.1133 HO Tortrix spp. B.1158 HO Oscinella spp.
B.1134 HO Trichoplusia ni B.1159 HO Phorbia spp.
B:1135 HO Agriotes spp. B.1160 HO Frankliniella spp.
B.1136 HO Anthonomus B.1161 HO Thrips spp.
grandis B.1162 HO Scirtothrips aurantii B.1137 HO Curculio spp. B.1163 HO Aceria spp.
B.1138 HO Diabrotica balteata B.1164 HO Aculus spp.
B.1139 HO Leptinotarsa spp. B.1165 HO Brevipaipus spp.
B.1140 HO Lissorhoptrus spp. B.1166 HO Panonychus spp.
B.1141 HO Otiorhynchus spp. B.1167 HO Phyllocoptruta spp.
B.1142 HO Aleurothrixus spp. B.1168 HO Tetranychus spp.
B.1143 HO Aleyrodes spp. B.1169 HO Heterodera spp.
B.1144 HO Aonidiella spp. B.1170 HO Meloidogyne spp.
Biological Examiples Table 1: A method of controlling pests comprising the application of thiamethoxam to transgenic cotton, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

Tablg2: A method of controlling pests comprising the application of thiamethoxam to transgenic rice, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individuaGsed combinations B.1 to B.1170 of table B.

Table 3: A method of controlling pests comprising the application of thiamethoxam to transgenic potatoes, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1 170 of table B.

Table 4: A method of controlling pests comprising the application of thiamethoxam to transgenic brassica, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1 170 of table B.

Table 5: A method of controlling pests comprising the apptication of thiamethoxam to transgenic tomatoes, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

Table 6: A method of controlling pests comprising the application of thiamethoxam to transgenic cucurbits, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1 170 of table B.

Table 7: A method of controlling pests comprising the application of thiamethoxam to transgenic soybeans, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

Table 8: A method of controlling pests comprising the application of thiamethoxam to transgenic maize, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1 170 of table B.

Table 9: A method of controlling pests comprising the application of thiamethoxam to transgenic wheat, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

Table 10: A method of controlling pests comprising the application of thiamethoxam to transgenic bananas, wherein the combination of the active principle expressed by the transgenic piant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1 170 of table B.

Table 11: A method of controlling pests comprising the application of thiamethoxam to transgenic citrus trees, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individuaiised combinations B.1 to B.1 170 of table B.

Table 12: A method of controlling pests comprising the application of thiamethoxam to transgenic pome fruit trees, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

Table 13: A method of controlling pests comprising the application of thiamethoxam to transgenic peppers, wherein the combination of the'active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1 170 of table B.

Table 14: A method of controlling pests comprising the application of imidacioprid to transgenic cotton, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1 170 of table B.

J'abie 15: A method of controlling pests comprising the application of imidacloprid to transgenic rice, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

T ba le 16: A method of controlling pests comprising the application of imidacloprid to transgenic potatoes, wherein the combination of the active principle expressed by the =86-transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

Table 17: A method of controlling pests comprising the application of imidadoprid to transgenic tomatoes, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

TabIe 18: A method of controlling pests comprising the application of imidacloprid to transgenic cucurbits, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

Table 19: A method of controlling pests comprising the application of imidaeloprid to transgenic soybeans, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

Table 20: A method of controlling pests comprising the application of imidacloprid to transgenic maize, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

Table 21: A method of controlling pests comprising the application of imidacioprid to transgenic wheat, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B. 1170 of table B.

Table 22: A method of controlling pests comprising the appGcation of imidacloprid to transgenic bananas, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individuabsed combinations B.1 to B.1170 of table B.

Table 23: A method of controlling pests comprising the application of imidacioprid to transgenic orange trees, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1 170 of table B.

WO 99/35913 pCT/EP99/00193 Table 24: A method of controlling pests comprising the application of imidacloprid to transgenic pome fruit, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1 170 of table B.

Table 25: A method of controlling pests comprising the appfication of imidacloprid to transgenic cucurbits, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond,to anyone of the individuaiised combinations B.1 to B.1170 of table B.

Table 26: A method of controlling pests comprising the application of imidacioprid to transgenic peppers, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1 170 of table B.

Tabie 27: A method of controlling pests comprising the application of Ti-435 to transgenic cotton, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individuallsed combinations B.1 to B.1170 of table B.

Table 28: A method of controifing pests comprising the application of Ti-435 to transgenic rice, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

Table 29: A method of controlling pests comprising the application of Ti-435 to transgenic potatoes, wherein the combination of the active principie expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

Table 30: A method of controlling pests comprising the application of Ti-435 to transgenic brassica, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

Table 31: A method of controlling pests comprising the application of Ti-435 to transgenic tomatoes, wherein the combination of the active principle expressed by the transgenic plant .gg.
and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

T I 32: A method of controlling pests comprising the apptication of Twt35 to transgenic cucurbits, wherein the combination of the active principle expressed by the tmnsgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

T I 33: A method of controlling pests comprising the apptication of Ti-435 to transgenic soybeans, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

T I 34: A method of controiiing pests comprising the application of Ti-435 to transgenic maize, wherein the combination of the active pdnciple expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1 170 of table B.

Ta I 35: A method of controlling pests comprising the application of Ti-435 to transgenic wheat, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

Table 36: A method of controlling pests comprising the application of Ti-435 to transgenic bananas, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1 170 of table B.

T I 37: A method of controlling pests comprising the application of Ti-435 to transgenic citrus trees, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

Table 38: A method of controlling pests comprising the application of Ti-435 to transgenic pome fruit trees, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

Table 39: A method of controlling pests comprising the application of thiacloprid to transgenic cotton, wherein the combination of the activve principle expressed by the transgenic plant and the pest to be controlled c:orrespond to anyone of the individuatised combinations B.1 to B.1 170 of table B.

Table 40: A method of controlting pests comprising the application of thiacloprid to transgenic rice, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

Table 41: A method of controlling pests comprising the application of thiacloprid to transgenic potatoes, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1 170 of table B.

Table 42: A method of controlling pests comprising the application of thiacloprid to transgenic brassica, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1 170 of table B.

T ba ie 48: A method of controlling pests comprising the application of thiacloprid to transgenic tomatoes, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individuaiised combinations B.1 to B.1 170 of table B.

Table 44: A method of controlling pests comprising the application of thiacloprid to transgenic cucurbits, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1 170 of table B.

Table 45: A method of controlling pests comprising the application of thiacloprid to transgenic soybeans, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

Ta I 46: A method of controlling pests comprising the application of thiacloprid to transgenic maize, wherein the combination of the active principle expressed by the WO 99l35913 PCTR'=P"/00183 transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

T I 47: A method of controlling pests comprising the application of thlacioprid to transgenic wheat, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individualised combinations B.1 to B.1170 of table B.

Ta I 48: A method of controlling pests comprising the appiication of thiactoprid to transgenic bananas, wherein the combination of the active principle expressed by the transgenic plant and the pest to be controlled correspond to anyone of the individuaiised combinations B.1 to B.1 170 of table B.

Table C:
Abbreviations:
Acetyl-COA Carboxylase: ACCase Acetolactate Synthase: ALS
Hydroxyphenylpyruvat dioxygenase: HPPD
Inhibition of protein synthesis: IPS
Hormone mimic: HO
Glutamine Synthetase: GS
Protoporphyrinogen oxidase: PROTOX
5-Enolpyruvyl-3-Phosphoshikimate Synthase: EPSPS

Principle Tolerant to Crop C.1 ALS Sulfonylureas etc."' Cotton C.2 ALS Sulfonylureas etc. Rice C.3 ALS Sulfonylureas etc. Brassica C.4 ALS Sulfonylureas etc. Potatoes C.5 ALS Sulfonyiureas etc. Tomatoes C.6 ALS Suifonylureas etc. Cucurbits C.7 ALS Sulfonylureas etc. Soybeans C.8 ALS Sulfonylureas etc. Maize C.9 ALS Sulfonylureas etc. Wheat C.10 ALS Sulfonylureas etc. pome fruit Principle Tolerant to Crop C.11 ALS Sulfonylureas etc. stone fruit C.12 ALS Sutfonytureas etc. citrus C.13 ACCase +++ Cotton C.14 ACCase +++ Rice C.15 ACCase +++ Brassica C.16 ACCase +++ Potatoes C.17 ACCase +++ Tomatoes C.18 ACCase +++ Cucurbits C.19 ACCase +++ Soybeans C.20 ACCase +++ Maize C.21 ACCase +++ Wheat C.22 ACCase +++ pome fruit C.23 ACCase +++ stone fruit C.24 ACCase Hi citrus C.25 HPPD Isoxaflutol, Isoxachiotol, Sutcotrion, Mesotrion Cotton C.26 HPPD Isoxaflutol, lsoxachlotol, Sulcotrion, Mesotrion Rice C.27 HPPD Isoxaftutol, Isoxachlotot, Sulcotrion, Mesotrion Brassica C.28 HPPD lsoxaflutol, isoxachlotol, Sulcotrion, Mesotrion Potatoes C.29 HPPD Isoxaftutol, lsoxachlotol, Sulcotrion, Mesotrion Tomatoes C.30 HPPD Isoxaflutol, lsoxachlotol, Sulcotrion, Mesotrion Cucurbits C.31 HPPD Isoxaflutol, lsoxachlotol, Sulcotrion, Mesotrion Soybeans C.32 HPPD lsoxafiutol, lsoxachlotol, Sulcotrion, Mesotrion Maize C.33 HPPD Isoxaflutol, lsoxachlotol, Sulcotrion, Mesotrion Wheat C.34 HPPD tsoxaflutol, lsoxachlotol, Sulcotrion, Mesotrion pome fruit C.35 HPPD Isoxaflutol, lsoxachlotol, Sulcotrion, Mesotrion stone fruit C.36 HPPD lsoxaflutol, Isoxachiotol, Sulcotrion, Mesotrion citrus C.37 Nitrilase Bromoxynil, loxynil Cotton C.38 Nitrilase Bromoxynil, loxynil Rice C.39 Nitrilase Bromoxynil, loxynil Brassica C.40 Nitritase Bromoxynil, loxynil Potatoes C.41 Nitrilase Bromoxynil, loxynil Tomatoes C.42 Nitriiase Bromoxynil, loxynil Cucurbits WO 99/35913 pGT/EP99/00183 Principle Toierant to Crop C.43 Nitrilase Bromoxynil, loxynil Soybeans C.44 Nitrilase Bromoxynil, loxynil Maize C.45 Nitrilase Bromoxynii, loxynil Wheat C.46 Nitrilase Bromoxynil, loxynil pome fruit C.47 Nitrilase Bromoxynil, loxynil stone fruit C.48 Nitrilase Bromoxynil, loxynil citrus C.49 IPS Chloroactanilides &&& Cotton C.50 IPS Chloroactanilides &&& Rice C.51 IPS Chloroactanilide &&&s Brassica C.52 IPS Chloroactanilides &&& Potatoes C.53 IPS Chloroactanilides &&& Tomatoes C.54 IPS Chloroactanilides &&& Cucurbits C.55 IPS Chloroactanilides &&& Soybeans C.56 IPS Chloroactanilides &&& Maize C.57 IPS Chioroactanilides &&& Wheat C.58 IPS Chloroactanilides &&& pome fruit C.59 IPS Chioroactanilides &&& stone fruit C.60 IPS Chloroactanilides &&& citrus C.61 HOM 2,4-D, Mecoprop-P Cotton C.62 HOM 2,4-D, Mecoprop-P Rice C.63 HOM 2,4-D, Mecoprop-P Brassica C.64 HOM 2,4-D, Mecoprop-P Potatoes C.65 HOM 2,4-D, Mecoprop-P Tomatoes C.66 HOM 2,4-D, Mecoprop-P Cucurbits C.67 HOM 2,4-D, Mecoprop-P Soybeans C.68 HOM 2,4-D, Mecoprop-P Maize C.69 HOM 2,4-D, Mecoprop-P Wheat C.70 HOM 2,4-D, Mecoprop-P pome fruit C.71 HOM 2,4-D, Mecoprop-P stone fruit C.72 HOM 2,4-D, Mecoprop-P citrus C.73 PROTOX Protox inhibitors Il/ Cotton C.74 PROTOX Protox inhibitors Il/ Rice WO 99l35913 PCT/EP99/00183 Principle Tolerent to Crop C.75 PROTOX Protox inhibitors Brassica C.76 PROTOX Protox inhibitors /// Potatoes C.77 PROTOX Protox inhibitors /// Tomatoes C.78 PROTOX Protox inhibitors /// Cucurbits C.79 PROTOX Protox inhibitors Ill Soybeans C.80 PROTOX Protox inhibitors Maize C.81 PROTOX Protox inhibitors Wheat C.82 PROTOX Protox inhibitors /// pome fruit C.83 PROTOX Protox inhibitors IlI stone truit C.84 PROTOX Protox inhibitors citrus C.85 EPSPS Glyphosate and /or Suiphosate Cotton C.86 EPSPS Glyphosate and /or Suiphosate Rice C.87 EPSPS Glyphosate and /or Sulphosate Brassica C.88 EPSPS Glyphosate and /or Suiphosate Potatoes C.89 EPSPS Glyphosate and /or Sulphosate Tomatoes C.90 EPSPS Glyphosate and /or Sutphosate Cucurbits C.91 EPSPS Glyphosate and /or Sulphosate Soybeans C.92 EPSPS Glyphosate and. /or Sulphosate Maize C.93 EPSPS Glyphosate and /or Sulphosate Wheat C.94 EPSPS Glyphosate and /or Suiphosate pome fruit C.95 EPSPS Glyphosate and /or Sulphosate stone fruit C.96 EPSPS Giyphosate and /or Sulphosate citrus C.97 GS Gluphosinate and /or Bialaphos Cotton C.98 GS Gluphosinate and /or Bialaphos Rice C.99 GS Gluphosinate and /or Bialaphos Brassica C.100 GS Gluphosinate and /or Bialaphos Potatoes C.101 GS Gluphosinate and /or Bialaphos Tomatoes C.102 GS Gluphosinate and /or Bialaphos Cucurbits C.103 GS Giuphosinate and /or Bialaphos Soybeans C.104 GS Gluphosinate and /or Bialaphos Maize C.105 GS Gluphosinate and /or Bialaphos Wheat C. 106 GS Gluphosinate and /or Bialaphos pome fruit Principie Tolerant to Crop C.107 GS Gluphosinate and /or Bialaphos stone fruit C.108 GS Gluphosinate and /or Bialaphos citrus Included are Sulfonylureas, imidazolinones, Triazolopyrimidines, Dimethoxypyrimidines and N-Acylsutfonamides:
Sulfonylureas such as Chiorsulfuron, Chlorimuron, Ethamethsulturon, IVletsulfuron, Primisuifuron, Prosulfuron, Triasulfuron, Cinosulfuron, Trifusulfuron, Oxasulfuron, Bensulfuron, Tribenuron, ACC 322140, Fluzasulfuron, Ethoxysuifuron, Fluzasdulfuron, Nicosulfuron, Rimsulfuron, Thifensulfuron, Pyrazosulfuron, Clopyrasutfuron, NC
330, Azimsulfuron, Imazosulfuron, Sulfosutfuron, Amidosulfuron, Flupyrsulfuron, CGA

Imidazolinones such as Imazamethabenz, Imazaquin, tmazamethypyr, imazethapyr, imazapyr and Imazamox;

Triazolopyrimidines such as DE 511, Flumetsulam and Chioransutam;
Dimethoxypyrimidines such as Pyrithiobac, Pyriminobac, Bispyribac and Pyribenzoxim.
+++ Tolerant to Diciofop-methyi, Fluazifop-P-butyt, Haloxyfop-P-methyl, Haioxytop-P-ethyl, Quizalaf op-P-ethyl , clodinafop propargyl, fenoxaprop - -ethyl, -Tepraloxydim, Alioxydim, Sethoxydim, Cycloxydim, Cloproxydim, Tralkoxydim, Butoxydim, Caloxydim, Ciefoxydim, Clethodim.

&&& Chioroacetaniiides such as Atachlor Acetochior, Dimethenamid lll Protox inhibitors: For instance diphenyethers such as Acifluorfen, Aclonifen, Bitenox, Chlomitrofen, Ethox}rfen, Fluorogiycofen, Fomesafen, Lactoten, Oxyfluorfen;
Imides such as Azafenidin, Carfentrazone-ethyl, Cinidon-ethyt, Flumiclorac-pentyl, Flumioxazin, Fluthiacet-methyl, Oxadiargyl, Oxadiazon, Pentoxazone, Sulfentn3zone, Imides and others,such as Flumipropyn, Flupropacil, Nipyraciofen and Thidiazimin; and further Fluazolate and Pyraflufen-ethyl Biological Examales Table 49: A method of controlling representatives of the genus Adoxophyes comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the .'_ combination of the active principle expressed by the tmnsgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Ta I 50: A method of controiling representatives of the genus Agrotis comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the Gnes C.1 to C.108 of table C.
Table 51: A method of controlling Alabama argillaceae comprising the application of thiamethoxam to a herbicidaliy resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 52: A method of controlling Anticarsia gemmatalis comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principie expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 53: A method of controlling representatives of the genus Chilo comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 54: A method of controlling Clysia ambiguelia comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

T le 55: A method of controlling representatives of the genus Cnephalocrocis comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 56: A method of controlling Crocidolomia binotalis comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 57: A method of controlling representatives of the genus Cydia comprising the application of thiamethoxam to a herbicidaliy resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

T ba le 58: A method of controlling Diparopsis castanea comprising the application of thiamethoxam to a herbicidally resistant trensgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 59: A method of controlling represeritatives of the genus Earias comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of tabie C.
Table 60: A method of controlling representatives of the genus Ephestia comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 61: A method of controlling representatives of the genus Heliothis comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 62: A method of controlling Hellula undalis comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the iines C.1 to C.108 of table C.

Table 63: A method of controlling Keiferia lycopersicelia comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic piant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 64: A method of controliing Leucoptera scitella comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 65: A method of controlling representatives of the genus Lithocollethis comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C. 1 to C. 108 of table C.

T b~66: A method of controlling Lobesia botrana comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 67: A method of controlling Ostrinia nubilalis comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle exNr4-csed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 68: A method of controlling representatives of the genus Pandemis comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 69: A method of controlling Pectinophora gossypielia comprising the application of thiamethoxam to a herbicidaiiy resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of tabie C.

Table 70: A method of controlling Phyllocnistis citrella comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 71: A method of controlling representatives of the genus Pieris comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

WO 99/35913 PC'j'/EP"/00183 Table 72: A method of controlling PluteOa xylostelia comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Ta I 7: A method of controlling representatives of the genus Scirpophaga comprising the application of tr~~amethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active prir ple expressed by the transgenic plant and the crop to be protected against the pest correspond :o anyone of the lines C.1 to C.108 of table C.
Table 74: A method of controlling representatives of the genus Sesamia comprising the application of thiamethoxam to a herbicidaAy resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the, lines C.1 to C.108 of table C.

Table 75: A method of controlling representatives of the genus Sparganothis comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

T I 76: A method of controlling representatives of the genus Spodoptera comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the iines C.1 to C.1 08 of table C.
Table 77: A method of controlling representatives ot the genus Tortrix comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 78: A method of controlling Trichoplusia ni comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 79: A method of controlling representatives of the genus Agriotes comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the WO 99/35913 PCT/Ep"/00183 combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

T 80: A method of controlling Anthonomus grandis comprising the appiication of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Tabgt~1: A method of controlting representatives of the genus Curculio comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 82: A method of controlling Diabrotica balteata comprising the application of thiamethoxam to a herbicidaliy resistant transgenic crop, wherein the combination ot the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 83: A method of controlling representatives of the genus Leptinotarsa comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 84: A method of controlling representatives of the genus Lissorhoptrus comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 85: A method of controlling representatives of the genus Otiorhynchus comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 86: A method of controlling representatives of the genus Aleurothrixus comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

WO 99/35913 PCT/EP"/00183 ab 87: A method of controAing representatives of the genus Aleyrodes comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 88: A method of controlling representatives of the genus Aonidiella comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 89: A method of controlling representatives of the family Aphididae comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 90: A method of controlling representatives of the genus Aphis comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 91: A method of controlling Bemisia tabaci comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principie expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

T ba le 92: A method of controlling representatives of the genus Empoasca comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 93: A method of controlling representatives of the genus Mycus comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the iines C.1 to C.108 of table C.
Table 94: A method of controlling representatives of the genus Nephotettix comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 95: A method of controlling representatives of the genus Nilaparvata comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.i to C.108 of table C.
Table 96: A method of controlling representatives of the genus Pseudococcus comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 97: A method of controlling representatives of the genus Psylla comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 98: A method of controlling representatives of the genus Quadraspidiotus comprising the application of thiamethoxam to a herbicidaily resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 99: A method of controlling representatives of the genus Schizaphis comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic piant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 100: A method of controlling representatives of the genus Trialeurodes comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 101: A method of controlling representatives of the genus Lyriomyza comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 102: A method of controlling representatives of the genus Oscinelia comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 103: A method of controlling representatives of the genus Phorbia comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principie expressed by the tranagenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 104: A method of controlling representatives of the genus Frankliniella comprising the application of thiamethoxam to w herbicidally resistant transgenic crop, wherein the combination of the active principle expreased by the transgenic plant and the crop to be protected against the pest correspond to anyone oi fhe lines C.1 to C.108 of table C.

Table 105: A method of controlling representatives of the genus Thrips comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 106: A method of controlling Scirtothrips aurantii comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 107: A method of controlling representatives of the genus Aceria comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 108: A method of controlling representatives of the genus Aculus comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 109: A method of controlling representatives of the genus Brevipaipus comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 11 : A method of controlling representatives of the genus Panonychus comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 111: A method of controlling representatives of the genus Phyllocoptruta comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.1 08 of table C.
Table 112: A method of controlling representatives of the genus Tetranychus comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 113: A method of controlling representatives of the genus Heterodera comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 114: A method of controlling representatives of the genus Meloidogyne comprising the application of thiamethoxam to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 115: A method of controlling Mamestra brassica comprising the application of thiamethoxam to a herbicidatly resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 116: A method of controlling representatives of the genus Adoxophyes comprising the application of imidactoprid to a herbicidally resistant transgenic crop, wherein the combination of the active principie expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.1 08 of table C.

.104-Table 117: A method of controlling- representatives of the genus Agrotis comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 118: A method of controlling Alabama argillaceae comprising the application of imidacioprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transganic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 119: A method of controlling Anticarsia gemmatatis comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 120: A method of controlling representatives of the genus Chilo comprising the application of imidacioprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 121: A method of controlling Clysia ambiguelia comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant. and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 122: A method of controlling representatives of the genus Cnephalocrocis comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 123: : A method of controlling Crocidolomia binotalis comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 124: A method of controlling representatives of the genus Cydia comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principie expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 125: A method of controlling Diparopsis castanea comprising the appiication of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 126: A method of controlling representatives of the genus Earias comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 127: A method of controlling representatives of the genus Ephestia comprising the application of imidacioprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 128: A method of controlling representatives of the genus Heiiothis of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the iines C.1 to C.108 of table C.

Table 129: A method of controlling Hellula undalis comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 130: A method of controlling Ke'rferia lycopersicella comprising the apptication of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 131: A method of controlling Leucoptera scitella comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

WO 99l35913 PCT/EP99/00183 Table 132: A method of controlling representatives of the genus Lithocollethis comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 133: A method of controlling Lobesia botrana comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protectec! against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 134: A method of controlling Ostrinia nubiialis comprising the.application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 135: A method of controlling representatives of the genus Pandemis comprising the application of imidactoprid to a herbicidalty resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic piant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 136: A method of controlling Pectinophora gossypiella comprising the application of imidacloprid to a herbicidatiy resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 137: A method of controlling Phyliocnistis citrella comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 138: A method of controlling representatives of the genus Pieris comprising the application of irnidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 139: A method of controlling Plutella xylostella comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the WO 99/35913 pCT/EP"/00183 active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 140: A method of controlling representatives of the genus Scirpophaga comprising the application of imidacioprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 141: A method of controlling representatives of the genus Sesamia comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 142: A method of controlling representatives of the genus Sparganothis comprising the application of imidacloprid to a hs t:ddally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 143: A method of controlling representatives of the genus Spodoptera comprising the application of imidacioprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 144: A method of controlling representatives of the genus Tortrix comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 145: A method of controlling Trichoplusia ni comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 146: A method of controlling representatives of the genus Agriotes comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.1 08 of table C.

Table 147: A method of controlling Anthonomus grandis comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 148: A method of controlling representatives of the genus Curculio comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combiridtion of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 149: A method of controlling Diabrotica balteata comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the iines C.1 to C.108 of table C.

Table 150: A method of controlling representatives of the genus Leptinotarsa comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 151: A method of controlling representatives of the genus Lissorhoptrus comprising the application of imidactoprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 152: A method of controlling representatives of the genus Otiorhynchus comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 153: A method of controlling representatives of the genus Aleurothrixus comprising the application of imidacfoprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 154: A method of controlling representatives of the genus Aleyrodes comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the WO 99/35913 PCT~~~183 combination of the active principie expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

T I 155: A method of controlling representatives of the genus Aonidielia comprising the application of imidacfoprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 156: A method of controlling representatives of the family Aphididae comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 157: A method of controlling representatives of the genus Aphis comprising the application of imidaClorrid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 158: A method of controlling Bemisia tabaci comprising the applica4on of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principie expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 159: A method of controlling representatives of the genus Empoasca comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 160: A method of controlling representatives of the genus Mycus comprising the appiication of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 161: A method of controlling representatives of the genus Nephotettix comprising the application of imidacioprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the iines C.1 to C.108 of table C.

WO 99/35913 PCT/EP"100183 T I 162: A method of controlling representatives of the genus Nitaparvata comprising the application of imidactoprid to a herbicidatly resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 163: A method of controlling representatives of the genus Pseudococcus comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the acuve pr~ncipte expressed by the t.ansgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 164: A method of controlling representatives of the genus Psylla comprising the application of imidactoprid to a herbicidally resistant trensgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 165: A method of controlling representatives of the genus Quadraspidiotus comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of tabte C.

Table 166: A method of controlling representatives of the genus Schizaphis comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 167: A method of controlling representatives of the genus Trialeurodes comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 168: A method of controlling representatives of the genus Lyriomyza comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 169: A method of controlling representatives of the genus Oscinelia comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

aZ ble 170: A method of controlling representatives of the genus Phorbia comprising the application of imidadoprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 171: A method of controlling representatives of the genus Franklinielia comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 172: A method of controlling representatives of the genus Thrips comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 173: A method of controlling Scirtothrips aurantii comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 174: A method of controlling representatives of the genus Aceria comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 175: A method of controlling representatives of the genus Aculus comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 176: A method of controliing representatives of the genus Brevipalpus comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

T bl~ e 177: A method of controlling representatives of the genus Panonychus comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
jgbig 178: A method of controlling representatives of the genus Phyllocoptruta comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenf:, plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 179: A method of controlling representatives of the genus Tetranychus comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of tabie C.
Table 180: A method of controiling representatives of the genus Heterodera comprising the application of imidacloprid to a herbicidaliy resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic piant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 181: A method of controlling representatives of the genus Meloidogyne comprising the application of imidacloprid to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
Table 182: A method of controlling representatives of the genus Adoxophyes comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 183: A method of controlling representatives of the genus Agrotis comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 184: A method of controlling Alabama argillaceae comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.i to C.108 of table C.

Table 185: A method of controlling Anticarsia gemmatalis comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 186: A method of controlling representatives of the genus Chilo comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 187: A method of controlling Clysia ambiguelia comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 188: A method of controlling Crocidolomia binotalis comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 189: A method of controlling representatives of the genus Cydia comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principie expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 190: A method of controlling Diparopsis castanea comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 191: A method of controlling representatives of the genus Earias comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

T bl : A method of controlling representatives of the genus Ephestia comprising the application of Ti-435 to a herbicidally resistant transgenic crop,. wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 193: A method of controlling representatives of the genus Heliothis of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant aiid the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 194: A method of controlling Hellula undalis comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 195: A method of controliing neiferia iycopersicella comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 196: A method of controlling Leucoptera scitella comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the iines C.1 to C.108 of table C.

Table 197: A method of controlling representatives of the genus Lithocollethis comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 198: A method of controlling Lobesia botrana comprising the application of TI-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 199: A method of controlling Ostrinia nubilalis comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the iines C.1 to C.108 of table C.

Table 200: A method of controlling representatives of the genus Pandemis comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the iines C.1 to C.108 of table C.

Table 201: A method of controlling PecKinophora gossypiella comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 202: A method of controlling Phyllocnistis citrelia comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 203: A method of controlling representatives of the genus Pieris comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 204: A method of controiling Plutella xylostella comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 205: A method of controiling representatives of the genus Scirpophaga comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 206: A method of controlling representatives of the genus Sesamia comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

WO 99/35913 pCT/Ep99/00183 Table 207: A method of controlling representatives of the genus Sparganothis comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 208: A method of controtiing representatives of the genus Spodoptera comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 209: A method of controlling representatives of the genus Tortrix comprising the appiication of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principte expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 210: A method of controlling Trichoplusia ni comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 211: A method of controlling representatives of the genus Agriotes comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 212: A method of controlling Anthonomus grandis comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 213: A method of controlling representatives of the genus Curculio comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 214: A method of controlling Diabrotica balteata comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the dnes C.1 to C.108 of table C.

Table 215: A method of controlling representatives of the genus Leptinotan3a comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transDenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 216: A method of controlling representatives of the genus Lissorhoptrus comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principie expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 217: A method of controlling representatives of the genus Otiorhymchus comprising the application of Ti-435 to a herbicidaiiy resistant transgenic crop, wherein the combination of the active principie expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 218: A method of controlling representatives of the genus Aieurothrixus comprising the application of Ti-435 to a herbicidaiiy resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 219: A method of controlling representatives of the genus Aleyrodes comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be.protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 220: A method of controlling representatives of the genus Aonidieiia comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principie expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 221: A method of controlling representatives of the family Aphididae comprising the application of Ti-435 to a herbicidaify resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

ja~e 222: A method of oontrotiing representatives of the genus Aphis comprising the application of Ti-435 to a herbicidaiiy resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 223: A method of controlling 8emisia tabaci oomprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the activve principle expressed by the transgenlc plant and the crop to be protected against the pest corresponM
to anyone of the lines C.1 to C.108 of table C.

Table 224: A method of controlling representatives of the genus Empoasca comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 225: A method of controlling representatives of the genus Mycus comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 226: A method of controlling representatives of the genus Nephotettix comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 227: A method of controlling representatives of the genus Nilaparvata comprising the application of 1-1-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 228: A method of controlling representatives of the genus Pseudococcus comprising the application of Ti-435 to a herbicidaiiy resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 229: A method of controiiing representatives of the genus Psylla comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of WO 99/35913 P(.'T/EP991o00183 the active principie expressed by the transgenic piant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 230: A method of controlling representatives of the genus Quadraspidiotus comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.
TAbie 231: A method of controiiing representatives of the genus Schizaphis comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principie expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Tabie 232: A method of controlling representatives of the genus Triaieurodes comprising the application of Ti-435 to a herbicida0y resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 233: A method of controiiing representatives of the genus Lyriomyza comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principie expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the fines C.1 to C.108 of table C.

Table 234: A method of controlling representatives of the genus Oscineiia comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 235: A method of controlling representatives of the genus Phorbia comprising the application of Ti-435 to a herbicidaUy resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 236: A method of controliing representatives of the genus Frankiinieiia comprising the application of Ti-435 to a herbicidaiiy resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 237: A method of controlling representatives of the genus Thrips comprising the application of Ti-435 to a herbicidaily resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

bi~ e 238: A method of controlling Scirtothrips aurantii comprising the appkation of Ti-435:
to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

T I 9 A method of controAing representatives of the genus Aceria comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 240: A method of controlling representatives of the genus Aculus comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 241: A method of controlling representatives of the genus Brevipaipus comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 242: A method of controlling representatives of the genus Panonychus comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wrherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Tablg 243: A method of controlling representatives of the genus Phyiiocoptruta comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

T I 244: A method of controlling representatives of the genus Tetranychus comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination WO 99/35913 PCT/EP99ro0183 of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

jAbie 245: A method of controlling representatives of the genus Heterodera comprising the apptication of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 246: A method of controlling representatives of the genus AAeloidogyne comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Tablg247: A method of controlling Mamestra brassica comprising the application of Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of the active principle expressed by the transgenic plant and the crop to be protected against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Examnle 131; Action against Anthonomus ar~ndis aduns. SpodQotera littoralis or Heliothis ylrescens Young transgenic cotton plants which express the 8-endotoxin Cry111A are sprayed with an aqueous emulsion spray mixture comprising 100, 50, 10, 5, 1 ppm of imidacloprid respectively. After the spray coating has dried on, the cotton plants are populated with 10 adult Anthonomus grandis, 10 Spodoptera littoralis larvae or 10 Heliothis virescens larvae respectively and introduced into a plastic container. Evaluation takes place 3 to 10 days later. The percentage reduction in population, or the percentage reduction in feeding damage (% action), is determined by comparing the number of dead beetles and the feeding damage on the transgenic cotton plants with that of non-transgenic cotton plants which have been treated with an emulsion spray mixture comprising imidacloprid and con-ventional CryIIIA-toxin at a concentration of in each case 100, 50, 10, 5, 1 ppm respectively.
In this test, the control of the tested insects in the transgenic plant is superior to the control on the non-transgenic plant.

Examgle B2: Action against AnthQnornus arandis adults. Snodootera littoralis or Heligthis virescens Young transgenic cotton plants which express the S-eridotoxin CryIIIA are sprayed wfth an aqueous emuision spray mixture comprising 100, 50,10, 5, 1 ppm of thiamethoxam respectively. After the spray coating has dried on, the cotton plants are populated with 10 aduft Anthonomus grandis, 10 Spodoptera littoralis larvae or 10 Heliothis virescens larvae respectively and introduced into a plastic container. Evaluation takes place 3 to 10 days later. The percentage reduction in population, or the percentage reduction in feeding damage (% action), is determined by comparing the number of dead bestlas and luliQ
feeding damage on the transgenic cotton plants with that of non-transgenic cotton plants which have been treated with an emulsion spray mixture comprising thiamethoxam and con-ventional CryI11A-toxin at a concentration of in each case 100, 50, 10, 5, 1 ppm respectively.
In this test, the control of the tested insects in the transgenic plant is superior, while it is insufficient in the non-transgenic plant.

Example 133: Action aaginst Anthonomus qrandis adults. S22dO2tera littoralis or Heliothis virescens Young transgenic cotton plants which express the 8-endotoxin Cryi11A are sprayed with an aqueous emulsion spray mixture comprising 100, 50, 10, 5, 1 ppm of Ti-435 respectively.
After the spray coating has dried on, the cotton plants are populated with 10 adult Anthonomus grandis, 10 Spodoptera littoralis larvae or 10 Heliothis virescens larvae respectively and introduced into a plastic container. Evaluation takes place 3 to 10 days later. The percentage reduction in population, or the percentage reduction in feeding damage (% action), is determined by comparing the number of dead beetles and the feeding damage on the transgenic cotton plants with that of non-transgenic cotton plants which have been treated with an emulsion spray mixture comprising Ti-435 and conven-tional CryIIIA-toxin at a concentration of in each case 100, 50, 10, S. 1 ppm respecaveiy.
In this test, the control of the tested insects in the transgenic plant is superior, while it is insufficient in the non-transgenic plant.

Examnle 84: Action against Anthonomus grandis aduits. Scodoutera Cittoraiis or Heliothis viresF_ea Young transgenic cotton plants which express the S-endotoxin Cryla(c) are sprayed with an aqueous emulsion spray mixture comprising 100, 50, 10, 5, 1 ppm of Ti-435 respectively.
After the spray coating has dried on, the cotton plants are populated with 10 adult Anthonomus grandis, 10 Spodoptera littoralis larvae or 10 Heliothis virescens larvae respectively and introduced into a piastic container. Evaluation takes place 3 to 10 days later. The percentage reduction in population, or the percentage reduction In feeding damage (% action), is determined by comparing the number of dead beetles and the feeding damage on the transgenic cotton plants with that of non-transgenic cotton plants which have been treated with an emulsion spray mixture comprising TI-435 and conven-tional CryIIIA-toxin at a concentration of in each case 100, 50, 10, 5, 1 ppm respectiveiy.
In this test, the contnoi of the tested insects in the transgenic plant Is superior, while It is insufficient in the non transgenic plant.

Examole J~5.~ Action against Anthonomus cmndis adults. SR0ootera littoraiis or Heliothis virescens Young transgenic cotton plants which express the S-endotoxin Cryla(c) are sprayed with an aqueous emulsion spray mixture comprising 100, 50,10, 5, 1 ppm of thiamethoxam respectively. After the spray coating has dried on, the cotton plants are populated with 10 adult Anthonomus grandis, 10 SNcdQQtera Ifttoralis larvae or 10 Heliothis virescens larvae respectively and introduced into a plastic container. Evaluation takes place 3 to 10 days later. The percentage reduction in poputation, or the penrentage reduction in feeding damage (% action), is determined by comparing the number of dead beetles and the feeding damage on the transgenic cotton plants with that of non-transgenic cotton plants which have been treated with an emulsion spray mixture comprising thiamethoxam and con-ventional CryIIIA-toxin at a concentration of in each case 100, 50, 10, 5, 1 ppm respectively.
In this test, the control of the tested insects in the transgenic plant is superior, while it is insufficient in the non-transgenic plant.

xamoie B6: Action aaaipst Anthonomus grandis adults. Soodoutera littoraiis or Heiiothis virescens Young transgenic cotton plants which express the S-endotoxin Cryla(c) are sprayed with an aqueous emulsion spray mixture comprising 100, 50,10, 5,1 ppm of imidacloprid respectively. After the spray coating has dried on, the cotton plants are populated with 10 adult Anthonomus grandis, 10 Spodoptera littoralis larvae or 10 Heliothis virescens larvae respectively and introduced into a plastic container. Evaluation takes place 3 to 10 days later. The percentage reduction in population, or the percentage reduction in feeding damage (% action), is determined by comparing the number of dead beetles and the feeding damage on the transgenic cotton plants with that of non-transgenic cotton plants which have been treated with an emulsion spray mbcture oomprising imidadoprid conven-tional CryillA-toxin at a ooncentration of In each case 100, 50, 10, 5, 1 ppm respectivveiy.
In this test, the control of the tested 'msects In the transgenic plant is superior, while it is insufficient in the non-transgenic plant.

Examole B7: Action aaainst Ostrinia nublialls. SDodoDtera snD. or Hetiothis aoD.

A plot (a) planted with maize cv. KnockOut and an adjacent plot (b) of the same size which is planted with conventional maize, both showing natural Infestation with Qstrin nubiialis. SDodootera sDD, or Heiiothis, are sprayed with an aqueous emuision spray mixture comprising 200, 100, 50, 10, 5, 1 ppm of Ti-435. Immediately afterwards, piot (b) is treated with an emulsion spray mixture comprising 200, 100, 50, 10, 5, 1 ppm of the endotoxin expressed by KnockOut . Evaluation takes place 6 days later. The percentage reduction in popuiation (% action) is determined by comparing the number of dead pests on the plants of plot (a) with that on the plants of plot (b).

Improved control of Ostrinia nubitaiis. $podoDtArB sflD. or Heiiothis is observed on the plants of plot (a), while plot (b) shows a controi level of not over 60%.

Examole B8: Action against Ostrinja nubiiaiis. SDodoDtera SDD. or Hetiothis sDD.

A plot (a) planted with maize cv. KnockOut and an adjacent plot (b) of the same size which is planted with conventional maize, both showing naturai infestation with Ostrinia nubiiaiis. SDodogtera sDD. or Heliothis, are sprayed with an aqueous emuision spray mixture comprising 200, 100, 50, 10, 5, 1 ppm of thiamethoxam. Immediately afterwards, plot (b) is treated with an emulsion spray mixture comprising 200, 100, 50, 10, 5, 1 ppm of the endotoxin expressed by KnockOut . Evaluation takes piace 6 days later. The percentage reduction in population (% action) is determined by comparing the number of dead pests on the piants of plot (a) with that on the plants of plot (b).

Improved control of Ostrinia nubiiai is. SDodoDtera sRD, or Heliothis Is observed on the plants of plot (a), while plot (b) shows a control level of not over 60%.

Examole B9: Action against Ostrinia nubiiaiis. SDodoDtera S(,D, or Heiiothis sDD.

A plot (a) planted with maize cv. KnockOut and an adjacent plot (b) of the same size which is planted with conventional maize, both showing natural infestation with Ostrinia nubiiaiis. ySDodoj2tera sQD. or Heliothis, are sprayed with an aqueous emulsion spray mixture WO 99/35913 pCT/EP"/00183 comprising 200, 100, 50,10, 5, 1 ppm of imidadoprid. Immediately afterwards, plot (b) is treated with an emulsion spray mixture comprising 200,100, 50, 10, 5, 1 ppm of the endotoxin expressed by KnodcOut . Evaluation takes place 6 days later. The percentage reduction in population (% action) is determined by comparing the number of dead pests on the plants of plot (a) with that on the plants of plot (b).

Improved control of Ostrinia nubilalis. SDodontera sDD. or Heliothis spp. is observed on the plants of plot (a), while plot (b) snows a control level of not over 60%.

Examole B10: Action against Diabrotica baiteata A plot (a) planted with maize seedlings cv. KnodcOut and an adjacent plot (b) of the same size which is planted with conventional maize are sprayed with an aqueous emulsion of a spray mixture comprising 400 ppm thiamethoxam. Immediately afterwards, plot (b) is treated with an emulsion spray mixture comprising 400 ppm of the endotoxin expressed by KnockOut . After the spray coating has dried on, the seedlings are populated with 10 Diabrotica balteata larvae in the second stage and transferred to a plastic container. The test is evaluated 6 days later. The percentage reduction in population (%
action) is deter-mined by comparing the number of dead pests on the plants of plot (a) with that on the plants of plot (b).

Improved control of Diabrotica balteata is observed on the plants of plot (a), while plot (b) shows a control level of not over 60%.

Exam lr~ e B11: Action aaainst Aehis gossvnii Cotton seedlings on a plot (a) expressing the S-endotoxin Cryllia on a plot (a) and conven-tional cotton seediings on a plot (b) are infected with Aphis gossypi and subsequentiy sprayed with a spray mixture comprising 400 ppm thiamethoxam. immediately afterwards, plot (b) is treated with an emulsion spray mixture comprising 400 ppm of the S-endotoxin Crylila. The seedlings of plot (a) and (b) are then incubated at 20 C. The test is evaluated after 3 and 6 days.

The percentage reduction in population (% action) is determined by comparing the number of dead pests on the plants of plot (a) with that on the plants of plot (b).
Improved control of Aphis gossypi is observed on the plants of plot (a), while plot (b) shows a control level of not over 60%.

Examgle B12: Action aaainst Frankiniella occidentaiis Cotton seedlings expressing the S-endotoxin Cryilia on a plot (a) and conventional cotton seedlings on a plot (b) are infected with Franklinielia occidentaiis and subsequently sprayed with a spray mixture comprising 400 ppm thiamethoxam. Immediately afterwards, plot (b) is treated with an emulsion spray mixture compriWng 400 ppm of the S-endotoxin Cryllla. The seedlings of plot (a) and (b) are then incubated at 20 C. The test is evaluated after 3 and 6 days.

The percentage reduction in population (% action) is determined by comparing the number of dead pests on the plants of plot (a) with that on the plants of plot (b).
Improved control of Franklinieila occidentalis is observed on the plants of plot (a), while plot (b) shows a control level of not over 60%.

Example B13: Action aqainst ghis gossy~ii Cotton seedlings expressing the S-endotoxin CrylA(c) on a plot (a) and conventional cotton seedlings on a plot (b) are infected with Aphis gossypii and subsequently sprayed with a spray mixture comprising 400 ppm thiamethoxam. Immediately afterwards, plot (b) is treated with an emulsion spray mixture comprising 400 ppm of the S-endotoxin Crylila.
The seedlings of plot (a) and (b) are then incubated at 20 C. The test is evaluated after 3 and 6 days.

The percentage reduction in population (% action) is determined by comparing the number of dead pests on the plants of plot (a) with that on the plants of plot (b).
Improved control of Aphis goss ii is observed on the plants of plot (a), while plot (b) shows a control level of not over 60%.

Examole B14: Action aoainst Franklinielia occidentalis Cotton seedlings expressing the 8-endotoxin Cryla(c) on a plot (a) and conventional cotton seedlings on a plot (b) are infected with Frankliniella occidentalis and subsequently sprayed with a spray mixture comprising 400 ppm thiamethoxam. Immediately afterwards, plot (b) is treated with an emulsion spray mixture comprising 400 ppm of the 8-endotoxin Cryla(c). The seedlings of plot (a) and (b) are then incubated at 20 C. The test is evaluated after 3 and 6 days.

The percentage reduction in population (% action) is determined by comparing the number of dead pests on the plants of plot (a) with that on the plants of plot (b).
improved control of Franldiniella occidentalis is observed on the piants of plot (a), while plot (b) shows a control level of not over 60%.

amcle B15: Action against Neohotettix cincticens Rice plants on a plot (a) expressing the S-endotoxin CrylA(b) and conventional rice plants on a plot (b) are sprayed with a spray mixture comprising 400 ppm thiamethoxam.
Immediately afterwards, plot (b) is treated wfth an emulsion spray mbcture comprising 400 ppm of the S-endotoxin CrylA(b). After the spray coating has dried on, the plants are infected with Nephotettix cincticeps of the 2nd and 3rd stages. The seedlings of plot (a) and (b) are then incubated at 20 C. The test is evaluated after 21 days.

The percentage reduction in population (% action) is determined by comparing the number of dead pests on the plants of plot (a' with that on the plants of plot (b).
Improved control of Nephotettix cincticeos is observed on the plants of plot (a), while plot (b) shows a control level of not over 60%.

Examrale B16: Action aaainst Nenhotettix cincticeps (systemic) Rice plants expressing the 8-endotoxin Cryla(b) are planted in a in pot (A) and conventional ice plants are planted in a pot (B). Pot (A) is placed in an aqueous emulsion containing 400 ppm thiamethoxam, whereas plot (B) is placed in a pot containing 400 ppm thiamethoxam and 400 ppm of the 8-endotoxin Cryl(b). The plants are subsequently infected with Nephotettix cincticeps larvae of the second and third stage. The test is evaluated after 6 days.

The percentage reduction in population (% action) is determined by comparing the number of dead pests on the plants of pot (A) with that on the plants of pot (B).
Improved control of Neohotettix cincticeQs is observed on the plants of pot (A), while pot (B) shows a control level of not over 60%.

Examole B17: Action aaainst Nitapanrata lucens Rice plants on a plot (a) expressing the S-endotoxin CryIA(b) and conventional rice plants on a plot (b) are infected with Nilaparvata lugens, subsequently sprayed with a spray mixture comprising 400 ppm thiamethoxam. Immediately afterwards, plot (b) is treated with an emulsion spray mixture comprising 400 ppm of the 8-endotoxin CryIA(b). The seedlings of plot (a) and (b) are then incubated at 20 C. The test is evaluated after 21 days.

WO 99l35913 PCT/EP99Po0183 The percentage reduction in population (% action) Is determined by comparing the number of dead pests on the plants of plot (a) with that on the plants of plot (b).
Improved control of Niiaoarvata luaiens is observed on the plants of plot (a), while plot (b) shows a control level of not over 60%.

Examcie 818: Action against Nilananrata fuaens [svatemic) Rice plants expressing the S-endotoxin CryIA(b) are planted in a in pot (A) and conventional rice plants are planted in a pot (B). Pot (A) is placed In an aqueous emulsion containing 400 ppm thiamethoxam, whereas plot (B) is place in a pot copntaining 400 ppm thiamethoxam and 400 ppm of the 8-endotoxin CryIA(b). The plants are subsequently infected with Nilaoarvata luaens larvae of the second and third stage. The test is evaluated after 6 days.
The percentage reduction in population (% action) is determined by comparing the number of dead pests on the plants of pot (A) with that on the plants of pot (B).
Improved control of Nephotettix cincticeps is observed on the plants of pot (A), while pot (B) shows a control level of not over 60%.

Examnle B19: Action against Neohotettix cincticegs Rice plants on a plot (a) expressing the S-endotoxin CrylA(c) and conventional rice plants on a plot (b) are sprayed with a spray mixture comprising 400 ppm thiamethoxam.
Immediately afterwards, plot (b) is treated with an emulsion spray mixture comprising 400 ppm of the 8-endotoxin CrylA(c). After the spray coating has dried on, the plants are infected with Nephotettix cincticeps of the 2nd and 3rd stages. The seedlings of plot (a) and (b) are then incubated at 20 C. The test is evaluated after 21 days.

The percentage reduction in popuiation (% acfion) is determined by comparing the number of dead pests on the plants of piot (a) with that on the plants of plot (b).
Improved control of Nenhotettix cincticecs is observed on the plants of plot (a), while plot (b) shows a control level of not over 60%.

Examale B20: Action against Nedhotettix cinctice2s (s emic) Rice plants expressing the S-endotoxin Cryla(c) are planted in a in pot (A) and conventional ice plants are planted in a pot (B). Pot (A) is placed in an aqueous emulsion containing 400 ppm thiamethoxam, whereas plot (B) is placed in a pot containing 400 ppm thiamethoxam and 400 ppm of the 8-endotoxin Cryi(c). The plants are subsequently infected with Nephotettix cincticeps larvae of the second and third stage. The test is evaluated after 6 days.

The percentage reduction in population (% action) is determined by comparing the number of dead pests on the plants of pot (A) with that on the plants of pot (B).
improved control of Nephotettix cincticens is observed on the plants of pot (A), while pot (B) shows a control level of not over 60%.

Exampie B21: Action aaainst Niiaoarvata lug2 Rice plants on a plot (a) expressing the S-endotoxin CrylA(c) and conventional rice plants on a plot (b) are infected with NiiaRarvata lugens, subsequently sprayed with a spray mixture comprising 400 ppm thiamethoxam. Immediately afterwards, plot (b) is treated with an emulsion spray mixture comprising 400 ppm of the 8-endotoxin CrylA(c). The seedlings of plot (a) and (b) are then incubated at 20 C. The test is evaluated after 21 days.

The percentage reduction in population (% acctieon) is determined by comparing the number of dead pests on the plants of plot (a) with that on the plants of plot (b).
Improved control of Nilaparvata lugens is observed on the plants of plot (a), while plot (b) shows a control level of not over 0%.

Exampie B22: Action against Niiacarvata iuaens la tys emicl Rice plants expressing the S-endotoxin CrylA(c) are planted in a in pot (A) and conventional rice plants are planted in a pot (B). Pot (A) is placed in an aqueous emulsion containing 400 ppm thiamethoxam, whereas plot (B) is place in a pot copntaining 400 ppm thiamethoxam and 400 ppm of the S-endotoxin CrylA(c). The plants are subsequently infected with Niiagarvata iu4ens larvae of the second and third stage. The test is evaluated after 6 days.
The percentage reduction in population (% action) is determined by comparing the number of dead pests on the plants of pot (A) with that on the plants of pot (B).
Improved control of Nephotettix cincticecs is observed on the plants of pot (A), while pot (B) shows a controi level of not over, 60 %.

Claims (8)

CLAIMS:
1. A method of controlling pests in crops of transgenic plants, wherein a pesticidal composition comprising a nitroimino- or nitroguanidino-compound selected from the group consisting of thiamethoxam, clothianidin and thiacloprid as the active ingredient and at least one auxiliary is applied to the pests or their environment.
2. The method according to claim 1, wherein the nitroimino- or nitroguanidino-compound is thiamethoxam.
3. The method according to claim 1, wherein the nitroimino- or nitroguanidino-compound is clothianidin.
4. The method according to claim 1, wherein the nitroimino- or nitroguanidino-compound is thiacloprid.
5. The method according to any one of claims 1 to 4, wherein the transgenic plant or propagation material thereof is treated.
6. The method according to any one of claims 1 to 5, wherein the crop of transgenic plants is maize.
7. The method according to any one of claims 1 to 5, wherein the crop of transgenic plants is soya beans.
8. The method according to claim 5, wherein the propagation material of the transgenic plant is treated.
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