CA2314357A1 - Transgenic animal model for degenerative diseases of cartilage - Google Patents
Transgenic animal model for degenerative diseases of cartilage Download PDFInfo
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- CA2314357A1 CA2314357A1 CA002314357A CA2314357A CA2314357A1 CA 2314357 A1 CA2314357 A1 CA 2314357A1 CA 002314357 A CA002314357 A CA 002314357A CA 2314357 A CA2314357 A CA 2314357A CA 2314357 A1 CA2314357 A1 CA 2314357A1
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- C—CHEMISTRY; METALLURGY
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0393—Animal model comprising a reporter system for screening tests
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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Landscapes
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6831297P | 1997-12-19 | 1997-12-19 | |
| US08/994,689 US6613958B1 (en) | 1997-12-19 | 1997-12-19 | Transgenic mouse model for degeneration of type II collagen in joints |
| US08/994,689 | 1997-12-19 | ||
| US60/068,312 | 1997-12-19 | ||
| PCT/US1998/027056 WO1999031969A2 (en) | 1997-12-19 | 1998-12-18 | Transgenic animal model for degenerative diseases of cartilage |
Publications (1)
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| CA2314357A1 true CA2314357A1 (en) | 1999-07-01 |
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|---|---|---|---|
| CA002314357A Abandoned CA2314357A1 (en) | 1997-12-19 | 1998-12-18 | Transgenic animal model for degenerative diseases of cartilage |
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|---|---|
| EP (1) | EP1040196A2 (ko) |
| JP (1) | JP2002533055A (ko) |
| KR (2) | KR100558288B1 (ko) |
| AU (2) | AU1931699A (ko) |
| CA (1) | CA2314357A1 (ko) |
| CZ (1) | CZ20002201A3 (ko) |
| IL (1) | IL136626A0 (ko) |
| WO (1) | WO1999031969A2 (ko) |
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| US7005295B1 (en) | 1997-04-16 | 2006-02-28 | Wyeth | β-amyloid peptide-binding proteins and polynucleotides encoding the same |
| US6787319B2 (en) | 1997-04-16 | 2004-09-07 | American Home Products Corp. | β-amyloid peptide-binding proteins and polynucleotides encoding the same |
| US20040006205A1 (en) * | 2001-04-03 | 2004-01-08 | Li Li | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| US7071164B2 (en) | 2001-08-16 | 2006-07-04 | Kimberly-Clark Worldwide, Inc. | Anti-cancer and wound healing compounds |
| US6906036B2 (en) | 2001-08-16 | 2005-06-14 | Kimberly-Clark Worldwide, Inc. | Anti-aging and wound healing compounds |
| US7186693B2 (en) | 2001-08-16 | 2007-03-06 | Kimberly - Clark Worldwide, Inc. | Metalloproteinase inhibitors for wound healing |
| AU2002359781A1 (en) * | 2001-12-20 | 2003-07-09 | The Regents Of The University Of California | Triple transgenic mouse model of alzheimer's disease |
| US7148194B2 (en) | 2002-12-30 | 2006-12-12 | Kimberly-Clark Worldwide, Inc. | Method to increase fibronectin |
| US7189700B2 (en) | 2003-06-20 | 2007-03-13 | Kimberly-Clark Worldwide, Inc. | Anti-chrondrosarcoma compounds |
| US8173861B2 (en) | 2006-05-01 | 2012-05-08 | Aarhus Universitet | Transgenic pig model for a hereditary neurodegenerative autosomal dominant disease |
| KR20170023209A (ko) | 2008-05-05 | 2017-03-02 | 노비뮨 에스 에이 | 항-ｉｌ-１７ａ／ｉｌ-１７ｆ 교차-반응성 항체 및 그의 사용 방법 |
| CN104974250A (zh) | 2009-05-05 | 2015-10-14 | 诺维莫尼公司 | 抗il-17f抗体及其使用方法 |
| KR101176139B1 (ko) * | 2010-05-20 | 2012-08-22 | 광주과학기술원 | 관절염 동물모델로서 연골 특이적 ＨＩＦ?２α 형질전환 마우스 및 이의 용도 |
| WO2015087916A1 (ja) * | 2013-12-12 | 2015-06-18 | 国立大学法人三重大学 | ヒトｍｍｐ２を発現するトランスジェニック非ヒト哺乳類動物 |
| KR102167443B1 (ko) * | 2019-03-25 | 2020-10-19 | 주식회사 카티프라임 | 체외 골관절염 모델 및 이를 이용한 골관절염 치료제 스크리닝 방법 |
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| DE19501032A1 (de) * | 1995-01-14 | 1996-07-18 | Max Delbrueck Centrum | Mittel zur Behandlung von rheumatischen Erkrankungen |
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| IL136626A0 (en) | 2001-06-14 |
| AU1931699A (en) | 1999-07-12 |
| KR100558288B1 (ko) | 2006-03-10 |
| AU2003257928A1 (en) | 2003-11-20 |
| EP1040196A2 (en) | 2000-10-04 |
| WO1999031969A3 (en) | 1999-11-25 |
| KR20010033289A (ko) | 2001-04-25 |
| JP2002533055A (ja) | 2002-10-08 |
| CZ20002201A3 (cs) | 2001-11-14 |
| KR20050109080A (ko) | 2005-11-17 |
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