CA2311921A1 - Inhibitors of farnesyl-protein transferase - Google Patents

Inhibitors of farnesyl-protein transferase Download PDF

Info

Publication number
CA2311921A1
CA2311921A1 CA002311921A CA2311921A CA2311921A1 CA 2311921 A1 CA2311921 A1 CA 2311921A1 CA 002311921 A CA002311921 A CA 002311921A CA 2311921 A CA2311921 A CA 2311921A CA 2311921 A1 CA2311921 A1 CA 2311921A1
Authority
CA
Canada
Prior art keywords
substituted
unsubstituted
alkyl
aryl
heterocycle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002311921A
Other languages
English (en)
French (fr)
Inventor
Terrence M. Ciccarone
S. Jane Desolms
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9807364.6A external-priority patent/GB9807364D0/en
Application filed by Individual filed Critical Individual
Publication of CA2311921A1 publication Critical patent/CA2311921A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002311921A 1997-12-04 1998-11-30 Inhibitors of farnesyl-protein transferase Abandoned CA2311921A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US6755297P 1997-12-04 1997-12-04
US60/067,552 1997-12-04
GB9807364.6 1998-04-06
GBGB9807364.6A GB9807364D0 (en) 1998-04-06 1998-04-06 Inhibitors of farnesyl-protein transferase
PCT/US1998/025325 WO1999027928A1 (en) 1997-12-04 1998-11-30 Inhibitors of farnesyl-protein transferase

Publications (1)

Publication Number Publication Date
CA2311921A1 true CA2311921A1 (en) 1999-06-10

Family

ID=26313441

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002311921A Abandoned CA2311921A1 (en) 1997-12-04 1998-11-30 Inhibitors of farnesyl-protein transferase

Country Status (4)

Country Link
EP (1) EP1035849A4 (de)
AU (1) AU1611199A (de)
CA (1) CA2311921A1 (de)
WO (1) WO1999027928A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9902987D0 (sv) 1999-08-24 1999-08-24 Astra Pharma Prod Novel compounds
US7211595B2 (en) 2000-11-30 2007-05-01 Abbott Laboratories Farnesyltransferase inhibitors
GB0104050D0 (en) 2001-02-19 2001-04-04 Astrazeneca Ab Chemical compounds
GB0107228D0 (en) 2001-03-22 2001-05-16 Astrazeneca Ab Chemical compounds
SE0103818D0 (sv) 2001-11-15 2001-11-15 Astrazeneca Ab Chemical compounds
KR100432577B1 (ko) 2002-02-08 2004-05-24 주식회사유한양행 이미다졸 유도체의 제조방법
SE0301369D0 (sv) 2003-05-09 2003-05-09 Astrazeneca Ab Chemical compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262537A (en) * 1993-03-19 1993-11-16 Anaquest, Inc. Derivatives of 4,5,6,7-tetrahydroimidazo-[4,5-c]pyridinyl-6-carboxylic acid
JP2000500502A (ja) * 1995-11-22 2000-01-18 メルク エンド カンパニー インコーポレーテッド ファルネシル―タンパク質トランスフェラーゼ阻害剤
AU703203B2 (en) * 1996-01-30 1999-03-18 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
EP0891360A4 (de) * 1996-04-03 2002-05-15 Merck & Co Inc Inhibitoren der farnesyl-protein transferase
AU706629B2 (en) * 1996-04-03 1999-06-17 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase

Also Published As

Publication number Publication date
EP1035849A1 (de) 2000-09-20
EP1035849A4 (de) 2001-09-12
AU1611199A (en) 1999-06-16
WO1999027928A1 (en) 1999-06-10

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Legal Events

Date Code Title Description
FZDE Discontinued