CA2310510A1 - Procede d'identification et d'inhibition de molecules fonctionnelles d'acide nucleique dans des cellules - Google Patents
Procede d'identification et d'inhibition de molecules fonctionnelles d'acide nucleique dans des cellules Download PDFInfo
- Publication number
- CA2310510A1 CA2310510A1 CA002310510A CA2310510A CA2310510A1 CA 2310510 A1 CA2310510 A1 CA 2310510A1 CA 002310510 A CA002310510 A CA 002310510A CA 2310510 A CA2310510 A CA 2310510A CA 2310510 A1 CA2310510 A1 CA 2310510A1
- Authority
- CA
- Canada
- Prior art keywords
- gene
- genes
- functional
- identifying
- egss
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
- C12N2310/126—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes involving RNAse P
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/976,220 US6013447A (en) | 1997-11-21 | 1997-11-21 | Random intracellular method for obtaining optimally active nucleic acid molecules |
US976,220 | 1997-11-21 | ||
US7985198P | 1998-03-30 | 1998-03-30 | |
US60/079,851 | 1998-03-30 | ||
PCT/US1998/024854 WO1999027135A2 (fr) | 1997-11-21 | 1998-11-20 | Procede d'identification et d'inhibition de molecules fonctionnelles d'acide nucleique dans des cellules |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2310510A1 true CA2310510A1 (fr) | 1999-06-03 |
CA2310510C CA2310510C (fr) | 2007-04-17 |
Family
ID=26762503
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002310510A Expired - Fee Related CA2310510C (fr) | 1997-11-21 | 1998-11-20 | Procede d'identification et d'inhibition de molecules fonctionnelles d'acide nucleique dans des cellules |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1032707A2 (fr) |
JP (1) | JP2001524317A (fr) |
AU (1) | AU732321B2 (fr) |
CA (1) | CA2310510C (fr) |
WO (1) | WO1999027135A2 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1034308A4 (fr) * | 1997-12-04 | 2002-04-03 | Smithkline Beecham Corp | Procede mettant en oeuvre des sequences antisens d'expression pour produire des cellules mutantes exprimees de maniere conditionnelle |
AU4186600A (en) * | 1999-03-31 | 2000-10-16 | Rosetta Inpharmatics, Inc. | Essential genes of yeast as targets for antifungal agents, herbicides, insecticides and anti-proliferation drugs |
GB9912965D0 (en) * | 1999-06-03 | 1999-08-04 | Oxford Biomedica Ltd | In vivo selection method |
GB9929744D0 (en) * | 1999-12-17 | 2000-02-09 | Univ Nottingham | Modifying micro-organisms |
JP2003528589A (ja) * | 1999-12-23 | 2003-09-30 | クサントス バイオメディスン アクチエンゲゼルシャフト | 核酸のスクリーニング方法 |
AU2008202554C1 (en) * | 2001-02-23 | 2011-07-07 | Dsm Ip Assets B.V. | Novel genes encoding novel proteolytic enzymes |
WO2012005982A2 (fr) * | 2010-07-06 | 2012-01-12 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Rapporteur pour une terminaison par la arn polymérase ii |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5168053A (en) * | 1989-03-24 | 1992-12-01 | Yale University | Cleavage of targeted RNA by RNAase P |
DE69303712T2 (de) * | 1992-04-28 | 1997-02-20 | Univ Yale | Gezielte spaltung von rna mittels eukaryontischer rnase p und externe führungssequenz |
JPH08507203A (ja) * | 1992-12-04 | 1996-08-06 | イノーバー ラボラトリーズ,インコーポレイテッド | 調節可能な核酸治療およびそれらの使用方法 |
AU4961996A (en) * | 1994-12-14 | 1996-07-03 | Innovir Laboratories, Inc. | Ribozyme-mediated inactivation of leukemia-associated rna |
EP0850318A1 (fr) * | 1995-09-13 | 1998-07-01 | Chiron Corporation | Procede et produit d'assemblage pour la recherche d'inhibiteurs d'activation de la transcription |
US5877162A (en) * | 1996-03-14 | 1999-03-02 | Innovir Laboratories, Inc. | Short external guide sequences |
US5976874A (en) * | 1996-08-16 | 1999-11-02 | Yale University | Phenotypic conversion of drug-resistant bacteria to drug-sensitivity |
WO1998032880A1 (fr) * | 1997-01-23 | 1998-07-30 | Immusol Incorporated | Analyse fonctionnelle et decouverte de genes a l'aide de banques de vecteurs de genes de ribozymes specifiques a une cible ou bien rendues aleatoires |
-
1998
- 1998-11-20 CA CA002310510A patent/CA2310510C/fr not_active Expired - Fee Related
- 1998-11-20 EP EP98959542A patent/EP1032707A2/fr not_active Withdrawn
- 1998-11-20 WO PCT/US1998/024854 patent/WO1999027135A2/fr active IP Right Grant
- 1998-11-20 AU AU15323/99A patent/AU732321B2/en not_active Ceased
- 1998-11-20 JP JP2000522276A patent/JP2001524317A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU1532399A (en) | 1999-06-15 |
CA2310510C (fr) | 2007-04-17 |
WO1999027135A3 (fr) | 1999-07-29 |
AU732321B2 (en) | 2001-04-12 |
EP1032707A2 (fr) | 2000-09-06 |
WO1999027135A2 (fr) | 1999-06-03 |
JP2001524317A (ja) | 2001-12-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20141120 |