CA2306246A1 - Proteines contenant un peptide signal et utilisation de ces dernieres - Google Patents

Proteines contenant un peptide signal et utilisation de ces dernieres Download PDF

Info

Publication number
CA2306246A1
CA2306246A1 CA002306246A CA2306246A CA2306246A1 CA 2306246 A1 CA2306246 A1 CA 2306246A1 CA 002306246 A CA002306246 A CA 002306246A CA 2306246 A CA2306246 A CA 2306246A CA 2306246 A1 CA2306246 A1 CA 2306246A1
Authority
CA
Canada
Prior art keywords
lsp
tap
nucleic acid
protein
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002306246A
Other languages
English (en)
Inventor
Yang Pan
David P. Gearing
Sean A. Mccarthy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Millennium Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2306246A1 publication Critical patent/CA2306246A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/524—Thrombopoietin, i.e. C-MPL ligand
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

On décrit de nouvelles molécules de polypeptides, de protéines et d'acide nucléique de LSP-1, PA-I et TAP-1. Cette invention concerne des protéines isolées et entières LSP-1, PA-I et TAP-1 ainsi que des protéines de fusion isolées, des peptides antigéniques LSP-1, PA-I et TAP-1 et des anticorps anti-LSP-1, anti-PA-I et anti-TAP-1. Cette invention concerne également des molécules d'acide nucléique LSP-1, PA-I et TAP-1, des vecteurs d'expression de recombinaison contenant une molécule d'acide nucléique de l'invention, des cellules hôtes dans lesquelles les vecteurs d'expression ont été introduits et des animaux transgéniques non humains dans lesquels un gène LSP-1, PA-I et TAP-1 a été introduit ou dissocié. On décrit également des procédés de diagnostic, de criblage et de thérapie dans lesquels on utilise les compositions de cette invention.
CA002306246A 1997-10-06 1998-10-06 Proteines contenant un peptide signal et utilisation de ces dernieres Abandoned CA2306246A1 (fr)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US6114397P 1997-10-06 1997-10-06
US6115997P 1997-10-06 1997-10-06
US6114997P 1997-10-06 1997-10-06
US60/061,159 1997-10-06
US60/061,149 1997-10-06
US60/061,143 1997-10-06
US420698A 1998-01-08 1998-01-08
US09/004,206 1998-01-08
US1067498A 1998-01-22 1998-01-22
US09/010,674 1998-01-22
US1434798A 1998-01-27 1998-01-27
US09/014,347 1998-01-27
PCT/US1998/021151 WO1999018243A1 (fr) 1997-10-06 1998-10-06 Proteines contenant un peptide signal et utilisation de ces dernieres

Publications (1)

Publication Number Publication Date
CA2306246A1 true CA2306246A1 (fr) 1999-04-15

Family

ID=27555481

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002306246A Abandoned CA2306246A1 (fr) 1997-10-06 1998-10-06 Proteines contenant un peptide signal et utilisation de ces dernieres

Country Status (4)

Country Link
EP (1) EP1029034A4 (fr)
AU (1) AU9790798A (fr)
CA (1) CA2306246A1 (fr)
WO (1) WO1999018243A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030105303A1 (en) 1996-12-06 2003-06-05 Schering Corporation, A New Jersey Corporation Isolated mammalian monocyte cell genes; related reagents
US7488590B2 (en) 1998-10-23 2009-02-10 Amgen Inc. Modified peptides as therapeutic agents
US6660843B1 (en) 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
EP1124961B9 (fr) 1998-10-23 2010-07-21 Kirin-Amgen Inc. Composes thrombopoietiques
AR022150A1 (es) * 1998-12-31 2002-09-04 Schering Corp Acidos nucleicos derivados de monocitos y composiciones y metodos relacionados
WO2005056837A2 (fr) * 2003-11-26 2005-06-23 Applera Corporation Polymorphismes genetiques associes a des troubles cardiovasculaires et a une reponse au medicament, leurs procedes de detection et d'utilisation
US8008453B2 (en) 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0948623B1 (fr) * 1996-12-06 2010-01-27 Schering Corporation Genes isoles de monocytes de mammifere et reactifs associes
EP0948531A1 (fr) * 1996-12-11 1999-10-13 Chiron Corporation Proteines humaines secretees

Also Published As

Publication number Publication date
WO1999018243A1 (fr) 1999-04-15
EP1029034A4 (fr) 2003-04-09
EP1029034A1 (fr) 2000-08-23
AU9790798A (en) 1999-04-27

Similar Documents

Publication Publication Date Title
US6194151B1 (en) Molecules of the TNF receptor superfamily and uses therefor
AU2009227915A1 (en) CRSP protein (Cysteine-Rich Secreted Proteins), nucleic acid molecules encoding them and uses therefor
CA2299055A1 (fr) Nouvelles molecules de la famille des proteines de type tango-77 et utilisations de ces molecules
WO1999025371A1 (fr) Nouvelles molecules de la famille de proteines apparentees a la follistatine et leurs utilisations
WO1999032632A1 (fr) Nouvelles molecules d'un facteur apparente a l'interleukine issu d'un embryon (edirf) et leurs utilisations
US6197551B1 (en) Spoil-1 protein and nucleic acid molecules and uses therefor
WO1999052945A9 (fr) MOLECULES DE LA FAMILLE DES PROTEINES RELIEES AUX BGCKr ET LEUR UTILISATION
US6225085B1 (en) LRSG protein and nucleic acid molecules and uses therefor
CA2306246A1 (fr) Proteines contenant un peptide signal et utilisation de ces dernieres
US20050032172A1 (en) Novel molecules of the FTHMA-070-related protein family and the T85-related protein family and uses thereof
WO1999054437A2 (fr) Nouvelles molecules de la famille des proteines liees a t125 et utilisations de celles-ci
AU753279B2 (en) Novel molecules of the T129-related protein family and uses thereof
CA2318743A1 (fr) Nouvelles molecules de la superfamille du recepteur du facteur de necrose tumorale et leurs utilisations
US20030082677A1 (en) Novel EDIRF, MTR-1, LSP-1, TAP-1, and PA-I molecules and uses therefor
US20020055474A1 (en) Novel molecules of the tnf ligand superfamily and uses therefor
EP1586660A1 (fr) Nouvelles molécules de la famille des protéines liées à T85 et utilisation des dites molécules
US20030082688A1 (en) Spoil protein and nucleic acid molecules and uses therefor
US20030059892A1 (en) Novel molecules of the TANGO-93-related protein family and uses thereof
EP1080101A1 (fr) Nouvelles molecules de la famille de proteines associees au t139 et utilisations correspondantes
WO1999067415A9 (fr) Nouvelles molecules de la famille de proteines associees a t110 et leurs utilisations
AU2013200856A1 (en) CRSP protein (Cysteine-Rich Secreted Proteins), nucleic acid molecules encoding them and uses thereof
AU2010236081A1 (en) CRSP protein (Cysteine-Rich Secreted Proteins), nucleic acid molecules encoding them and uses therefor

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued