CA2300148C - Nicotine antagonists for nicotine-responsive neuropsychiatric disorders - Google Patents
Nicotine antagonists for nicotine-responsive neuropsychiatric disorders Download PDFInfo
- Publication number
- CA2300148C CA2300148C CA002300148A CA2300148A CA2300148C CA 2300148 C CA2300148 C CA 2300148C CA 002300148 A CA002300148 A CA 002300148A CA 2300148 A CA2300148 A CA 2300148A CA 2300148 C CA2300148 C CA 2300148C
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- Prior art keywords
- nicotine
- mecamylamine
- effective amount
- tics
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5523497P | 1997-08-11 | 1997-08-11 | |
| US60/055,234 | 1997-08-11 | ||
| US93536497A | 1997-09-22 | 1997-09-22 | |
| US08/935,364 | 1997-09-22 | ||
| PCT/US1997/020689 WO1999007356A1 (en) | 1997-08-11 | 1997-11-07 | Nicotine antagonists for neuropsychiatric disorders |
| USPCT/US97/20689 | 1997-11-07 | ||
| PCT/US1998/016634 WO1999007378A1 (en) | 1997-08-11 | 1998-08-11 | Nicotine antagonists for nicotine-responsive neuropsychiatric disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2300148A1 CA2300148A1 (en) | 1999-02-18 |
| CA2300148C true CA2300148C (en) | 2009-06-23 |
Family
ID=27368798
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002300148A Expired - Fee Related CA2300148C (en) | 1997-08-11 | 1998-08-11 | Nicotine antagonists for nicotine-responsive neuropsychiatric disorders |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JP4640888B2 (https=) |
| AU (1) | AU8778498A (https=) |
| CA (1) | CA2300148C (https=) |
| DK (1) | DK1011678T3 (https=) |
| ES (1) | ES2299214T3 (https=) |
| WO (1) | WO1999007378A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL348107A1 (en) * | 1998-10-16 | 2002-05-06 | Janssen Pharmaceutica Nv | Therapy for improving cognition |
| GB0102841D0 (en) * | 2001-02-05 | 2001-03-21 | Novartis Ag | Organic compounds |
| WO2005063296A2 (en) * | 2003-12-23 | 2005-07-14 | Pfizer Products Inc. | Therapeutic combination for cognition enhancement and psychotic disorders |
| EP1863485A2 (en) * | 2005-03-18 | 2007-12-12 | Abbott Laboratories | Alpha7 neuronal nicotinic receptor ligand and antipsychotic compositions |
| US11766429B1 (en) | 2020-08-26 | 2023-09-26 | University Of South Florida | Nicotinic receptor antagonists and pioglitazone as therapeutic agents for Covid-19 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5691365A (en) * | 1995-07-18 | 1997-11-25 | University Of Kentucky Research Foundation | Nicotinic receptor antagonists in the treatment of neuropharmacological disorders |
-
1998
- 1998-08-11 AU AU87784/98A patent/AU8778498A/en not_active Abandoned
- 1998-08-11 WO PCT/US1998/016634 patent/WO1999007378A1/en not_active Ceased
- 1998-08-11 JP JP2000506968A patent/JP4640888B2/ja not_active Expired - Fee Related
- 1998-08-11 ES ES98939328T patent/ES2299214T3/es not_active Expired - Lifetime
- 1998-08-11 CA CA002300148A patent/CA2300148C/en not_active Expired - Fee Related
- 1998-08-11 DK DK98939328T patent/DK1011678T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| JP4640888B2 (ja) | 2011-03-02 |
| JP2003524573A (ja) | 2003-08-19 |
| ES2299214T3 (es) | 2008-05-16 |
| WO1999007378A1 (en) | 1999-02-18 |
| CA2300148A1 (en) | 1999-02-18 |
| AU8778498A (en) | 1999-03-01 |
| DK1011678T3 (da) | 2008-05-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20180813 |