CA2299687C - Formation, tributaire du ph, et a temperature controlee, de gels de polysaccharide ionique - Google Patents

Formation, tributaire du ph, et a temperature controlee, de gels de polysaccharide ionique Download PDF

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Publication number
CA2299687C
CA2299687C CA002299687A CA2299687A CA2299687C CA 2299687 C CA2299687 C CA 2299687C CA 002299687 A CA002299687 A CA 002299687A CA 2299687 A CA2299687 A CA 2299687A CA 2299687 C CA2299687 C CA 2299687C
Authority
CA
Canada
Prior art keywords
polysaccharide
chitosan
gel solution
based gel
phosphate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002299687A
Other languages
English (en)
Other versions
CA2299687A1 (fr
Inventor
Abdellatif Chenite
Cyril Chaput
Christele Combes
Fayrouz Jalal
Amine Selmani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith and Nephew Orthopaedics AG
Original Assignee
Biosyntech Canada Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA002212300A external-priority patent/CA2212300A1/fr
Application filed by Biosyntech Canada Inc filed Critical Biosyntech Canada Inc
Priority to CA002299687A priority Critical patent/CA2299687C/fr
Publication of CA2299687A1 publication Critical patent/CA2299687A1/fr
Application granted granted Critical
Publication of CA2299687C publication Critical patent/CA2299687C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/49—Phosphorus-containing compounds
    • C08K5/51—Phosphorus bound to oxygen
    • C08K5/52—Phosphorus bound to oxygen only
    • C08K5/521—Esters of phosphoric acids, e.g. of H3PO4
CA002299687A 1997-08-04 1998-04-06 Formation, tributaire du ph, et a temperature controlee, de gels de polysaccharide ionique Expired - Lifetime CA2299687C (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002299687A CA2299687C (fr) 1997-08-04 1998-04-06 Formation, tributaire du ph, et a temperature controlee, de gels de polysaccharide ionique

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CA002212300A CA2212300A1 (fr) 1997-08-04 1997-08-04 Gelification in vitro ou in vivo du chitosane et utilisations therapeutiques du chitosane
CA2,212,300 1997-08-04
PCT/CA1998/000326 WO1999007416A1 (fr) 1997-08-04 1998-04-06 FORMATION, TRIBUTAIRE DU pH, ET A TEMPERATURE CONTROLEE, DE GELS DE POLYSACCHARIDE IONIQUE
CA002299687A CA2299687C (fr) 1997-08-04 1998-04-06 Formation, tributaire du ph, et a temperature controlee, de gels de polysaccharide ionique

Publications (2)

Publication Number Publication Date
CA2299687A1 CA2299687A1 (fr) 1999-02-18
CA2299687C true CA2299687C (fr) 2009-10-27

Family

ID=31888797

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002299687A Expired - Lifetime CA2299687C (fr) 1997-08-04 1998-04-06 Formation, tributaire du ph, et a temperature controlee, de gels de polysaccharide ionique

Country Status (1)

Country Link
CA (1) CA2299687C (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9200039B2 (en) 2013-03-15 2015-12-01 Symic Ip, Llc Extracellular matrix-binding synthetic peptidoglycans
US9217016B2 (en) 2011-05-24 2015-12-22 Symic Ip, Llc Hyaluronic acid-binding synthetic peptidoglycans, preparation, and methods of use

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8846003B2 (en) 2008-03-27 2014-09-30 Symic Biomedical, Inc. Collagen-binding synthetic peptidoglycans, preparation, and methods of use
JP5898682B2 (ja) * 2010-08-27 2016-04-06 オリゴ・メディック・インコーポレーテッド 高度に生体適合性の二重熱ゲル化キトサン／グルコサミン塩組成物
US8506972B2 (en) 2010-08-27 2013-08-13 Oligo Medic Inc Highly biocompatible dual thermogelling chitosan/glucosamine salt compositions
US10772931B2 (en) 2014-04-25 2020-09-15 Purdue Research Foundation Collagen binding synthetic peptidoglycans for treatment of endothelial dysfunction
CN110809478A (zh) 2017-07-07 2020-02-18 斯米克Ip有限公司 合成的生物缀合物
CN109957115A (zh) * 2017-12-25 2019-07-02 成都昕才医药科技有限公司 一种温敏水凝胶
CN114874039A (zh) * 2022-05-18 2022-08-09 普洱学院 一种咖啡果皮有机肥料及其制备方法
CN114948760A (zh) * 2022-05-24 2022-08-30 上海家化联合股份有限公司 含有水杨酸的多糖基凝胶及其应用

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9217016B2 (en) 2011-05-24 2015-12-22 Symic Ip, Llc Hyaluronic acid-binding synthetic peptidoglycans, preparation, and methods of use
US9200039B2 (en) 2013-03-15 2015-12-01 Symic Ip, Llc Extracellular matrix-binding synthetic peptidoglycans

Also Published As

Publication number Publication date
CA2299687A1 (fr) 1999-02-18

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Effective date: 20180406