CA2299389A1 - Radiolabeled peptides for the diagnosis and treatment of breast and prostate tumors and metastases of such tumors - Google Patents
Radiolabeled peptides for the diagnosis and treatment of breast and prostate tumors and metastases of such tumors Download PDFInfo
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- CA2299389A1 CA2299389A1 CA002299389A CA2299389A CA2299389A1 CA 2299389 A1 CA2299389 A1 CA 2299389A1 CA 002299389 A CA002299389 A CA 002299389A CA 2299389 A CA2299389 A CA 2299389A CA 2299389 A1 CA2299389 A1 CA 2299389A1
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- 102000014187 peptide receptors Human genes 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 229910000073 phosphorus hydride Inorganic materials 0.000 description 1
- 231100000683 possible toxicity Toxicity 0.000 description 1
- 229940124606 potential therapeutic agent Drugs 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 229940097325 prolactin Drugs 0.000 description 1
- 208000030153 prolactin-producing pituitary gland adenoma Diseases 0.000 description 1
- 201000001514 prostate carcinoma Diseases 0.000 description 1
- 238000000159 protein binding assay Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000005258 radioactive decay Effects 0.000 description 1
- 239000000700 radioactive tracer Substances 0.000 description 1
- 238000009877 rendering Methods 0.000 description 1
- 238000013391 scatchard analysis Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 230000009870 specific binding Effects 0.000 description 1
- 108010004034 stable plasma protein solution Proteins 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 201000011549 stomach cancer Diseases 0.000 description 1
- 229910052713 technetium Inorganic materials 0.000 description 1
- GKLVYJBZJHMRIY-UHFFFAOYSA-N technetium atom Chemical compound [Tc] GKLVYJBZJHMRIY-UHFFFAOYSA-N 0.000 description 1
- 229940127044 therapeutic radiopharmaceutical Drugs 0.000 description 1
- FJFIOAKCGFEILW-UHFFFAOYSA-N thian-2-imine Chemical class N=C1CCCCS1 FJFIOAKCGFEILW-UHFFFAOYSA-N 0.000 description 1
- 125000002813 thiocarbonyl group Chemical group *C(*)=S 0.000 description 1
- CNHYKKNIIGEXAY-UHFFFAOYSA-N thiolan-2-imine Chemical class N=C1CCCS1 CNHYKKNIIGEXAY-UHFFFAOYSA-N 0.000 description 1
- 229910052718 tin Inorganic materials 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- ILJSQTXMGCGYMG-UHFFFAOYSA-N triacetic acid Chemical compound CC(=O)CC(=O)CC(O)=O ILJSQTXMGCGYMG-UHFFFAOYSA-N 0.000 description 1
- 229960001124 trientine Drugs 0.000 description 1
- 210000004881 tumor cell Anatomy 0.000 description 1
- 230000004614 tumor growth Effects 0.000 description 1
- 230000036325 urinary excretion Effects 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 201000002715 uterus leiomyosarcoma Diseases 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- C07K7/086—Bombesin; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8807498P | 1998-06-05 | 1998-06-05 | |
| US60/088,074 | 1998-06-05 | ||
| US8851798P | 1998-06-08 | 1998-06-08 | |
| US60/088,517 | 1998-06-08 | ||
| PCT/US1999/012414 WO1999062563A2 (en) | 1998-06-05 | 1999-06-03 | Radiolabeled peptides for the diagnosis and treatment of breast and prostate tumors and metastases of such tumors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2299389A1 true CA2299389A1 (en) | 1999-12-09 |
Family
ID=26778250
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002299389A Abandoned CA2299389A1 (en) | 1998-06-05 | 1999-06-03 | Radiolabeled peptides for the diagnosis and treatment of breast and prostate tumors and metastases of such tumors |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1001977B1 (enExample) |
| JP (1) | JP4295921B2 (enExample) |
| AT (1) | ATE305940T1 (enExample) |
| CA (1) | CA2299389A1 (enExample) |
| DE (1) | DE69927568T2 (enExample) |
| DK (1) | DK1001977T3 (enExample) |
| ES (1) | ES2247835T3 (enExample) |
| WO (1) | WO1999062563A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6869591B2 (en) * | 2002-03-26 | 2005-03-22 | Barnes-Jewish Hospital | Paramagnetic particles that provide improved relaxivity |
| US8420050B2 (en) | 2003-01-13 | 2013-04-16 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
| US7611692B2 (en) | 2003-01-13 | 2009-11-03 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
| US7226577B2 (en) | 2003-01-13 | 2007-06-05 | Bracco Imaging, S. P. A. | Gastrin releasing peptide compounds |
| US7922998B2 (en) | 2003-01-13 | 2011-04-12 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
| US7850947B2 (en) | 2003-01-13 | 2010-12-14 | Bracco Imaging S.P.A. | Gastrin releasing peptide compounds |
| KR20080072686A (ko) * | 2005-11-29 | 2008-08-06 | 말린크로트, 인코포레이티드 | 이관능성 금속 킬레이팅 컨쥬게이트 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5750646A (en) * | 1987-09-24 | 1998-05-12 | The Administrators Of The Tulane Educational Fund | Bradykinin analogs with non-peptide bond |
| AU638043B2 (en) * | 1989-07-20 | 1993-06-17 | Novartis Ag | Labeled polypeptide derivatives |
-
1999
- 1999-06-03 JP JP2000551817A patent/JP4295921B2/ja not_active Expired - Fee Related
- 1999-06-03 ES ES99955223T patent/ES2247835T3/es not_active Expired - Lifetime
- 1999-06-03 EP EP99955223A patent/EP1001977B1/en not_active Expired - Lifetime
- 1999-06-03 DE DE69927568T patent/DE69927568T2/de not_active Expired - Lifetime
- 1999-06-03 DK DK99955223T patent/DK1001977T3/da active
- 1999-06-03 CA CA002299389A patent/CA2299389A1/en not_active Abandoned
- 1999-06-03 AT AT99955223T patent/ATE305940T1/de not_active IP Right Cessation
- 1999-06-03 WO PCT/US1999/012414 patent/WO1999062563A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP4295921B2 (ja) | 2009-07-15 |
| EP1001977B1 (en) | 2005-10-05 |
| ATE305940T1 (de) | 2005-10-15 |
| ES2247835T3 (es) | 2006-03-01 |
| DE69927568D1 (de) | 2006-02-16 |
| WO1999062563A2 (en) | 1999-12-09 |
| JP2002516882A (ja) | 2002-06-11 |
| WO1999062563A3 (en) | 2000-02-10 |
| EP1001977A2 (en) | 2000-05-24 |
| DE69927568T2 (de) | 2006-06-14 |
| DK1001977T3 (da) | 2005-12-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued | ||
| FZDE | Discontinued |
Effective date: 20080103 |