CA2297900A1 - Naphtyl urees de l'acide phosphonique et son utilisation anti-antiogenique et anti-tumorigenique - Google Patents

Naphtyl urees de l'acide phosphonique et son utilisation anti-antiogenique et anti-tumorigenique Download PDF

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Publication number
CA2297900A1
CA2297900A1 CA002297900A CA2297900A CA2297900A1 CA 2297900 A1 CA2297900 A1 CA 2297900A1 CA 002297900 A CA002297900 A CA 002297900A CA 2297900 A CA2297900 A CA 2297900A CA 2297900 A1 CA2297900 A1 CA 2297900A1
Authority
CA
Canada
Prior art keywords
suramin
substituted
phosphoric acid
acid
phosphonic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002297900A
Other languages
English (en)
Inventor
Delwood C. Collins
Antonio R. Gagliardi
Peter Nickel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Kentucky Research Foundation
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/899,966 external-priority patent/US5831347A/en
Priority claimed from US09/121,124 external-priority patent/US6096730A/en
Application filed by Individual filed Critical Individual
Priority claimed from PCT/US1998/015470 external-priority patent/WO1999005148A1/fr
Publication of CA2297900A1 publication Critical patent/CA2297900A1/fr
Abandoned legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne de nouveaux agents substitués à l'acide phosphonique et leurs compositions pharmaceutiques. Ces nouveaux agents sont définis par la formule suivante: (P-Yn1)m1-Q-K-(Q2-(Yn2-P)m2)j dans laquelle Y représente -OCO-, NR1CO- ou CON(R1)R2-; Q1 et Q2 représentent des groupes aryle substitués ou non substitués; K représente H, -NHCONH-, NHCS-NH, -NHCO-R3- ou -NHCSR3-CSNH-; à condition que K représente H, j représente 0; j représente 0,1,2; n1 et n2 représentent indépendamment 0,1 ou 2; et m1 et m2 représentent indépendamment un entier compris entre 1 et 4.
CA002297900A 1997-07-24 1998-07-24 Naphtyl urees de l'acide phosphonique et son utilisation anti-antiogenique et anti-tumorigenique Abandoned CA2297900A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/899,966 1997-07-24
US08/899,966 US5831347A (en) 1996-10-09 1997-07-24 Apparatus for determining if the duration of a power failure exceeded predetermined limits
US09/121,124 US6096730A (en) 1997-07-24 1998-07-23 Phosphonated agents and their antiangiogenic and antitumorigenic use
US09/121,124 1998-07-23
PCT/US1998/015470 WO1999005148A1 (fr) 1997-07-24 1998-07-24 Agents phosphonates et leur utilisation anti-angiogenique et anti-tumorigene

Publications (1)

Publication Number Publication Date
CA2297900A1 true CA2297900A1 (fr) 1999-02-04

Family

ID=31890787

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002297900A Abandoned CA2297900A1 (fr) 1997-07-24 1998-07-24 Naphtyl urees de l'acide phosphonique et son utilisation anti-antiogenique et anti-tumorigenique

Country Status (1)

Country Link
CA (1) CA2297900A1 (fr)

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