CA2297024A1 - Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament - Google Patents
Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament Download PDFInfo
- Publication number
- CA2297024A1 CA2297024A1 CA002297024A CA2297024A CA2297024A1 CA 2297024 A1 CA2297024 A1 CA 2297024A1 CA 002297024 A CA002297024 A CA 002297024A CA 2297024 A CA2297024 A CA 2297024A CA 2297024 A1 CA2297024 A1 CA 2297024A1
- Authority
- CA
- Canada
- Prior art keywords
- medicament
- inhalation
- flow diverting
- dry powder
- inhalator
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
- A61M15/0093—Inhalators mechanically breath-triggered without arming or cocking, e.g. acting directly on the delivery valve
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
Abstract
This invention is an inhalation activated inhalator (210) having a primary inhalation passage (230b), a secondary inhalation passage (248), a flow diverting mechanism (240), and a blocking plate (280), where the flow diverting mechanism and the blocking plate are each actuated by user inhalation.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/823,139 US5823183A (en) | 1995-08-02 | 1997-03-25 | Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament |
PCT/US1997/013461 WO1999006092A1 (en) | 1997-03-25 | 1997-07-29 | Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2297024A1 true CA2297024A1 (en) | 1999-02-11 |
CA2297024C CA2297024C (en) | 2006-05-23 |
Family
ID=26792679
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002297024A Expired - Lifetime CA2297024C (en) | 1997-03-25 | 1997-07-29 | Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament |
Country Status (9)
Country | Link |
---|---|
US (1) | US5823183A (en) |
EP (1) | EP1003583B1 (en) |
JP (1) | JP3790423B2 (en) |
AT (1) | ATE328626T1 (en) |
AU (1) | AU731677B2 (en) |
CA (1) | CA2297024C (en) |
ES (1) | ES2265157T3 (en) |
PT (1) | PT1003583E (en) |
WO (1) | WO1999006092A1 (en) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040237961A1 (en) * | 1995-06-08 | 2004-12-02 | Snow John Medlin | Inhalation actuated device for use with metered dose inhalers (MDIs) |
US6672304B1 (en) | 1995-06-08 | 2004-01-06 | Innovative Devices, Llc | Inhalation actuated device for use with metered dose inhalers (MDIs) |
GB9513218D0 (en) * | 1995-06-29 | 1995-09-06 | Fisons Plc | Inhalation device and method |
US6209538B1 (en) * | 1995-08-02 | 2001-04-03 | Robert A. Casper | Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament |
US5988163A (en) * | 1995-08-02 | 1999-11-23 | Innovative Devices | Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of delivery of medicament |
SE9503344D0 (en) * | 1995-09-27 | 1995-09-27 | Astra Ab | Inhalation device |
AP1342A (en) | 1998-03-16 | 2004-12-15 | Nektar Therapeutics | Aerosolized active agent delivery. |
UA73924C2 (en) | 1998-10-09 | 2005-10-17 | Nektar Therapeutics | Device for delivering active agent formulation to lungs of human patient |
FR2787031B1 (en) * | 1998-12-11 | 2001-03-30 | Valois Sa | IMPROVED INHALATION DEVICE |
GB9905538D0 (en) * | 1999-03-10 | 1999-05-05 | Glaxo Group Ltd | A device |
US6606992B1 (en) * | 1999-06-30 | 2003-08-19 | Nektar Therapeutics | Systems and methods for aerosolizing pharmaceutical formulations |
US6149914A (en) * | 1999-07-12 | 2000-11-21 | Patel; Jitendra Rambhai | Asthma treatment |
AU1068401A (en) * | 1999-10-12 | 2001-04-23 | Shl Medical Ab | Inhaler |
US6948494B1 (en) | 2000-05-10 | 2005-09-27 | Innovative Devices, Llc. | Medicament container with same side airflow inlet and outlet and method of use |
US7080644B2 (en) * | 2000-06-28 | 2006-07-25 | Microdose Technologies, Inc. | Packaging and delivery of pharmaceuticals and drugs |
GB2364919A (en) * | 2000-07-21 | 2002-02-13 | Cambridge Consultants | Inhalers |
SE517228C2 (en) * | 2000-09-25 | 2002-05-14 | Microdrug Ag | Dry powder inhaler with respiratory activation |
GB2380410B (en) * | 2001-10-05 | 2003-11-19 | Alchemy Healthcare Ltd | Apparatus for the nasal or oral delivery of a medicament |
US6779520B2 (en) * | 2001-10-30 | 2004-08-24 | Iep Pharmaceutical Devices Inc. | Breath actuated dry powder inhaler |
JP4422794B2 (en) | 2002-03-22 | 2010-02-24 | クリニカル・デザインズ・リミテッド | Administration device and manufacturing method thereof |
US7185651B2 (en) * | 2002-06-18 | 2007-03-06 | Nektar Therapeutics | Flow regulator for aerosol drug delivery and methods |
GB0304000D0 (en) | 2003-02-21 | 2003-03-26 | Clinical Designs Ltd | Dispenser |
US20070267032A1 (en) * | 2003-11-18 | 2007-11-22 | Yansong Shan | Healthy Pleasurable Inhalation Device |
GB0327112D0 (en) | 2003-11-21 | 2003-12-24 | Clincial Designs Ltd | Dispenser and reservoir |
GB0328859D0 (en) | 2003-12-12 | 2004-01-14 | Clinical Designs Ltd | Dispenser and counter |
US7861712B2 (en) | 2004-04-23 | 2011-01-04 | Manta Product Development | Sealed capsule including an integrated puncturing mechanism |
DK1799289T3 (en) * | 2004-09-16 | 2012-05-29 | Giampiero Cossi | Disposable single dose inhaler for powdered drugs |
US8771257B2 (en) * | 2004-10-15 | 2014-07-08 | Boston Scientific Scimed, Inc. | Drug delivery sheath |
GB0425518D0 (en) | 2004-11-19 | 2004-12-22 | Clinical Designs Ltd | Substance source |
EP1917057A4 (en) * | 2005-07-20 | 2017-05-03 | Manta Devices, LLC | Inhalation device |
US8763605B2 (en) | 2005-07-20 | 2014-07-01 | Manta Devices, Llc | Inhalation device |
GB0518400D0 (en) | 2005-09-09 | 2005-10-19 | Clinical Designs Ltd | Dispenser |
US20080163610A1 (en) * | 2007-01-05 | 2008-07-10 | Matthew Thomas Baird | Method and system for regenerating exhaust system filtering and catalyst components using variable high engine idle |
WO2009008001A2 (en) * | 2007-04-30 | 2009-01-15 | Sun Pharma Advanced Research Company Limited | Inhalation device |
US11224704B2 (en) | 2007-07-06 | 2022-01-18 | Manta Devices, Llc | Dose delivery device for inhalation |
CN101795723B (en) | 2007-07-06 | 2013-06-19 | 蒙塔设备有限公司 | Inhalation devices for storing and delivering medicament |
ES2648196T3 (en) | 2008-02-07 | 2017-12-29 | The University Of Washington | Circumferential spray device |
UA101056C2 (en) | 2008-10-08 | 2013-02-25 | Астразенека Аб | Inhalation device and method of dispensing medicament |
US8550074B2 (en) | 2009-01-15 | 2013-10-08 | Manta Devices, Llc | Delivery device and related methods |
GB0904059D0 (en) | 2009-03-10 | 2009-04-22 | Euro Celtique Sa | Counter |
GB0904040D0 (en) | 2009-03-10 | 2009-04-22 | Euro Celtique Sa | Counter |
WO2011085022A1 (en) | 2010-01-05 | 2011-07-14 | Microdose Therapeutx, Inc. | Inhalation device and method |
WO2011116293A2 (en) | 2010-03-19 | 2011-09-22 | Manta Devices, Llc | Delivery device and related methods |
DK2646094T3 (en) * | 2010-11-29 | 2015-07-06 | Sanofi Aventis Deutschland | MEDICINE MODULE FOR AN INHALATOR |
AU2012223160B2 (en) | 2011-03-03 | 2016-08-18 | Impel Pharmaceuticals Inc. | Nasal drug delivery device |
CA2835208C (en) | 2011-05-09 | 2019-08-20 | Impel Neuropharma, Inc. | Nozzles for nasal drug delivery |
US11103659B2 (en) | 2011-07-06 | 2021-08-31 | Manta Devices, Llc | Delivery device and related methods |
US9649454B2 (en) | 2012-05-03 | 2017-05-16 | Manta Devices, Llc | Delivery device and related methods |
CA2909954C (en) | 2013-04-28 | 2021-03-23 | Impel Neuropharma, Inc. | Medical unit dose container |
US9849257B2 (en) * | 2013-08-22 | 2017-12-26 | Trudell Medical International | Oscillating positive respiratory pressure device |
NO2709641T3 (en) * | 2014-03-10 | 2018-05-12 | ||
US11147936B2 (en) | 2014-05-02 | 2021-10-19 | Manta Devices, Llc | Dose delivery device with cover connected to dose chamber seal |
IL257845B (en) | 2015-09-10 | 2022-07-01 | Impel Neuropharma Inc | In-line nasal delivery device |
IT201600093878A1 (en) | 2016-09-19 | 2018-03-19 | Hollycon Italy Pte Ltd S R L | SINGLE-DOSE INHALER TO LOSE FOR POWDER MEDICINES |
EP3713628A4 (en) | 2017-11-21 | 2021-08-18 | Impel Neuropharma Inc. | Intranasal device with dip tube |
WO2019104192A1 (en) | 2017-11-21 | 2019-05-31 | Impel Neuropharma, Inc. | Intranasal device with inlet interface |
BR112020013744A8 (en) | 2018-01-05 | 2022-10-18 | Impel Neuropharma Inc | DIHYDROERGOTAMINE INTRANASAL DISPENSATION BY PRECISION OLFATIVE DEVICE |
CN111836615A (en) | 2018-01-05 | 2020-10-27 | 英倍尔药业股份有限公司 | Intranasal delivery of olanzapine by precision nasal device |
CN112955134A (en) | 2018-07-19 | 2021-06-11 | 英倍尔药业股份有限公司 | Respiratory delivery of levodopa and dopa decarboxylase inhibitors for the treatment of parkinson's disease |
WO2020069559A1 (en) * | 2018-10-02 | 2020-04-09 | Palmer Raymond Denis | A respiratory passage sprayer and method of use of same |
AU2019418744B2 (en) | 2019-01-03 | 2023-08-03 | Impel Pharmaceuticals Inc. | Nasal drug delivery device |
KR20220010011A (en) | 2019-05-17 | 2022-01-25 | 임펠 뉴로파마 인코포레이티드 | Disposable nasal delivery device |
FR3115996A1 (en) * | 2020-11-06 | 2022-05-13 | Nemera La Verpilliere | Product Distribution Support System |
CN113750331B (en) * | 2021-08-18 | 2022-08-16 | 华中科技大学 | Dry powder inhaler |
Family Cites Families (29)
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IT941426B (en) * | 1971-07-17 | 1973-03-01 | Isf Spa | SWIRL-CHAMBER INHALER FOR POWDER-SHAPING MEDICINAL SUBSTANCES |
FR2224175B1 (en) * | 1973-04-04 | 1978-04-14 | Isf Spa | |
GB1479283A (en) * | 1973-07-23 | 1977-07-13 | Bespak Industries Ltd | Inhaler for powdered medicament |
IT1016489B (en) * | 1974-03-18 | 1977-05-30 | Isf Spa | INHALER |
IT1017153B (en) * | 1974-07-15 | 1977-07-20 | Isf Spa | APPARATUS FOR INHALATIONS |
SE438261B (en) * | 1981-07-08 | 1985-04-15 | Draco Ab | USE IN A DOSHALATOR OF A PERFORED MEMBRANE |
FI79651C (en) * | 1982-10-08 | 1990-02-12 | Glaxo Group Ltd | Dosing device for medicine |
GB8328808D0 (en) * | 1983-10-28 | 1983-11-30 | Riker Laboratories Inc | Inhalation responsive dispensers |
FI69963C (en) * | 1984-10-04 | 1986-09-12 | Orion Yhtymae Oy | DOSERINGSANORDNING |
US4805811A (en) * | 1985-03-29 | 1989-02-21 | Aktiebolaget Draco | Dosage device |
SE448277B (en) * | 1985-04-12 | 1987-02-09 | Draco Ab | INDICATOR DEVICE WITH A DOSAGE DEVICE FOR MEDICINAL PRODUCTS |
US4811731A (en) * | 1985-07-30 | 1989-03-14 | Glaxo Group Limited | Devices for administering medicaments to patients |
GB8909891D0 (en) * | 1989-04-28 | 1989-06-14 | Riker Laboratories Inc | Device |
IT1237118B (en) * | 1989-10-27 | 1993-05-18 | Miat Spa | MULTI-DOSE INHALER FOR POWDER DRUGS. |
US5201308A (en) * | 1990-02-14 | 1993-04-13 | Newhouse Michael T | Powder inhaler |
DE4004904A1 (en) * | 1990-02-16 | 1990-09-13 | Gerhard Brendel | DRUM APPLICATOR |
US5192548A (en) * | 1990-04-30 | 1993-03-09 | Riker Laboratoires, Inc. | Device |
IT1243344B (en) * | 1990-07-16 | 1994-06-10 | Promo Pack Sa | MULTI-DOSE INHALER FOR POWDER MEDICATIONS |
DE4133274A1 (en) * | 1991-08-22 | 1993-02-25 | Boehringer Ingelheim Kg | Device for inhaling medicament - has internal mechanism actuated by breathing of user to mix powder with air |
DE4027390C2 (en) * | 1990-08-30 | 1994-11-03 | Boehringer Ingelheim Kg | Propellant-free inhalation device |
FR2667509B1 (en) * | 1990-10-04 | 1995-08-25 | Valois | POWDER INHALER, DEVICE FOR PACKAGING POWDER MICRODOSES IN THE FORM OF BANDS SUITABLE FOR USE IN A POWDER INHALER, AND METHOD FOR MANUFACTURING SUCH BANDS. |
GB9024760D0 (en) * | 1990-11-14 | 1991-01-02 | Riker Laboratories Inc | Inhalation device and medicament carrier |
US5161524A (en) * | 1991-08-02 | 1992-11-10 | Glaxo Inc. | Dosage inhalator with air flow velocity regulating means |
DE4142238A1 (en) * | 1991-12-20 | 1993-06-24 | Boehringer Ingelheim Kg | POWDER INHALATOR WITH POWDER SUPPORT FROM REGULAR MICROSTRUCTURES |
US5437271A (en) * | 1993-04-06 | 1995-08-01 | Minnesota Mining And Manufacturing Company | Deagglomerators for dry powder inhalers |
GB9314614D0 (en) * | 1993-07-14 | 1993-08-25 | Minnesota Mining & Mfg | Dry powder inhalers |
US5388572A (en) * | 1993-10-26 | 1995-02-14 | Tenax Corporation (A Connecticut Corp.) | Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same |
US5483954A (en) * | 1994-06-10 | 1996-01-16 | Mecikalski; Mark B. | Inhaler and medicated package |
US5692496A (en) * | 1995-08-02 | 1997-12-02 | Innovative Devices, Llc | Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament |
-
1997
- 1997-03-25 US US08/823,139 patent/US5823183A/en not_active Expired - Lifetime
- 1997-07-29 WO PCT/US1997/013461 patent/WO1999006092A1/en active IP Right Grant
- 1997-07-29 AT AT97935233T patent/ATE328626T1/en not_active IP Right Cessation
- 1997-07-29 JP JP2000504901A patent/JP3790423B2/en not_active Expired - Lifetime
- 1997-07-29 PT PT97935233T patent/PT1003583E/en unknown
- 1997-07-29 CA CA002297024A patent/CA2297024C/en not_active Expired - Lifetime
- 1997-07-29 AU AU38220/97A patent/AU731677B2/en not_active Expired
- 1997-07-29 ES ES97935233T patent/ES2265157T3/en not_active Expired - Lifetime
- 1997-07-29 EP EP97935233A patent/EP1003583B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
PT1003583E (en) | 2006-09-29 |
AU3822097A (en) | 1999-02-22 |
US5823183A (en) | 1998-10-20 |
JP2001511402A (en) | 2001-08-14 |
ES2265157T3 (en) | 2007-02-01 |
AU731677B2 (en) | 2001-04-05 |
EP1003583B1 (en) | 2006-06-07 |
EP1003583A1 (en) | 2000-05-31 |
JP3790423B2 (en) | 2006-06-28 |
EP1003583A4 (en) | 2001-04-11 |
CA2297024C (en) | 2006-05-23 |
ATE328626T1 (en) | 2006-06-15 |
WO1999006092A1 (en) | 1999-02-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |
Effective date: 20170731 |