CA2291959A1 - Composition nutraceutique de l-carnitine, d'ubiquinone, d'acides gras n-3 polyinsatures et de vitamines specialement formules en doses pharmacologiques pour ameliorer les elementsrelatifs aux facteurs de risque et aux symptomes de maladies reliees a l'atherosclerose - Google Patents

Composition nutraceutique de l-carnitine, d'ubiquinone, d'acides gras n-3 polyinsatures et de vitamines specialement formules en doses pharmacologiques pour ameliorer les elementsrelatifs aux facteurs de risque et aux symptomes de maladies reliees a l'atherosclerose Download PDF

Info

Publication number
CA2291959A1
CA2291959A1 CA002291959A CA2291959A CA2291959A1 CA 2291959 A1 CA2291959 A1 CA 2291959A1 CA 002291959 A CA002291959 A CA 002291959A CA 2291959 A CA2291959 A CA 2291959A CA 2291959 A1 CA2291959 A1 CA 2291959A1
Authority
CA
Canada
Prior art keywords
vitamin
derivatives
daily dose
carnitine
functionally equivalent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002291959A
Other languages
English (en)
Inventor
Alex P. Korn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CA002291959A priority Critical patent/CA2291959A1/fr
Publication of CA2291959A1 publication Critical patent/CA2291959A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/375Ascorbic acid, i.e. vitamin C; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415Pyridoxine, i.e. Vitamin B6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135Compounds containing heavy metals
    • A61K31/714Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002291959A 1999-12-08 1999-12-08 Composition nutraceutique de l-carnitine, d'ubiquinone, d'acides gras n-3 polyinsatures et de vitamines specialement formules en doses pharmacologiques pour ameliorer les elementsrelatifs aux facteurs de risque et aux symptomes de maladies reliees a l'atherosclerose Abandoned CA2291959A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002291959A CA2291959A1 (fr) 1999-12-08 1999-12-08 Composition nutraceutique de l-carnitine, d'ubiquinone, d'acides gras n-3 polyinsatures et de vitamines specialement formules en doses pharmacologiques pour ameliorer les elementsrelatifs aux facteurs de risque et aux symptomes de maladies reliees a l'atherosclerose

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002291959A CA2291959A1 (fr) 1999-12-08 1999-12-08 Composition nutraceutique de l-carnitine, d'ubiquinone, d'acides gras n-3 polyinsatures et de vitamines specialement formules en doses pharmacologiques pour ameliorer les elementsrelatifs aux facteurs de risque et aux symptomes de maladies reliees a l'atherosclerose

Publications (1)

Publication Number Publication Date
CA2291959A1 true CA2291959A1 (fr) 2001-06-08

Family

ID=4164833

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002291959A Abandoned CA2291959A1 (fr) 1999-12-08 1999-12-08 Composition nutraceutique de l-carnitine, d'ubiquinone, d'acides gras n-3 polyinsatures et de vitamines specialement formules en doses pharmacologiques pour ameliorer les elementsrelatifs aux facteurs de risque et aux symptomes de maladies reliees a l'atherosclerose

Country Status (1)

Country Link
CA (1) CA2291959A1 (fr)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007006672A1 (fr) * 2005-07-08 2007-01-18 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Utilisation d'une combinaison comprenant de la l-carnitine ou de l'alkanoyl l-carnitine, de la benzoquinone liposoluble et des acides gras omega-3-polyinsatures pour la preparation d'un complement alimentaire ou d'un medicament destine au traitement de maladies de la cornee
US7439267B2 (en) 2001-01-25 2008-10-21 Pfizer Italia S.R.L. Essential n-3 fatty acids in cardiac insufficiency and heart failure therapy
US8173618B2 (en) 2003-07-25 2012-05-08 University Of Massachusetts Formulations for reducing neuronal degeneration
EP2340824A3 (fr) * 2001-11-14 2012-05-30 N.V. Nutricia Procédé et préparation permettant de réduire la sévérité d'ADHD et/ou des troubles moteurs
US8597640B2 (en) 2007-10-31 2013-12-03 University Of Massachusetts Lowell Over-the-counter vitamin/nutriceutical formulation that provides neuroprotection and maintains or improves cognitive performance in alzheimer's disease and normal aging
RU2643943C2 (ru) * 2016-05-06 2018-02-06 Государственное бюджетное образовательное учреждение высшего профессионального образования "Воронежский государственный медицинский университет им. Н.Н. Бурденко" Министерства здравоохранения Российской Федерации Способ оценки и коррекции неврологического статуса на основе мониторинга параметров окислительного стресса у пациентов с ишемическим инсультом
CN112885455A (zh) * 2021-01-18 2021-06-01 复旦大学附属中山医院 一种心力衰竭分型模型及试剂盒
CN116869971A (zh) * 2023-08-02 2023-10-13 广东润和生物科技有限公司 一种辅酶q10缓释软胶囊以及制备方法

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7439267B2 (en) 2001-01-25 2008-10-21 Pfizer Italia S.R.L. Essential n-3 fatty acids in cardiac insufficiency and heart failure therapy
US9844525B2 (en) 2001-11-14 2017-12-19 N.V. Nutricia Preparation for improving the action of receptors
EP2340824A3 (fr) * 2001-11-14 2012-05-30 N.V. Nutricia Procédé et préparation permettant de réduire la sévérité d'ADHD et/ou des troubles moteurs
US9504712B2 (en) 2001-11-14 2016-11-29 N.V. Nutricia Preparation for improving the action of receptors
US8173618B2 (en) 2003-07-25 2012-05-08 University Of Massachusetts Formulations for reducing neuronal degeneration
JP2009500374A (ja) * 2005-07-08 2009-01-08 シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ 角膜疾患の治療のための食餌サプリメントまたは医薬の調製のためのl−カルニチンまたはアルカノイルl−カルニチン、脂溶性ベンゾキノンおよびオメガ−3−多価不飽和脂肪酸を含む組合せの使用
AU2006268787B2 (en) * 2005-07-08 2012-02-02 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Use of a combination comprising L-carnitine or alkanoyl L-carnitine, lipid solubl benzoquinone and omega-3-polyunsaturated fatty acid for the preparation of a dietary supplement or medicament for the treatment of corneal diseases
US8349317B2 (en) 2005-07-08 2013-01-08 Sigma-Tau Industrie Farmaceutiche Riunite Spa Use of L-carnitine or an alkanoyl L-carnitine, for the preparation of a dietary supplement or medicament for the treatment of corneal disease
KR101262076B1 (ko) * 2005-07-08 2013-05-08 시그마타우 인두스트리에 파르마슈티케 리우니테 에스.피.에이. 각막 질환의 치료를 위한 식이 보조제 또는 의약품의제조를 위한 l-카르니틴 또는 알카노일 l-카르니틴, 지질수용성 벤조퀴논 및 오메가-3-다불포화 지방산을 포함하는병용제의 용도
WO2007006672A1 (fr) * 2005-07-08 2007-01-18 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Utilisation d'une combinaison comprenant de la l-carnitine ou de l'alkanoyl l-carnitine, de la benzoquinone liposoluble et des acides gras omega-3-polyinsatures pour la preparation d'un complement alimentaire ou d'un medicament destine au traitement de maladies de la cornee
US8597640B2 (en) 2007-10-31 2013-12-03 University Of Massachusetts Lowell Over-the-counter vitamin/nutriceutical formulation that provides neuroprotection and maintains or improves cognitive performance in alzheimer's disease and normal aging
RU2643943C2 (ru) * 2016-05-06 2018-02-06 Государственное бюджетное образовательное учреждение высшего профессионального образования "Воронежский государственный медицинский университет им. Н.Н. Бурденко" Министерства здравоохранения Российской Федерации Способ оценки и коррекции неврологического статуса на основе мониторинга параметров окислительного стресса у пациентов с ишемическим инсультом
CN112885455A (zh) * 2021-01-18 2021-06-01 复旦大学附属中山医院 一种心力衰竭分型模型及试剂盒
CN112885455B (zh) * 2021-01-18 2024-02-27 复旦大学附属中山医院 一种心力衰竭分型模型及试剂盒
CN116869971A (zh) * 2023-08-02 2023-10-13 广东润和生物科技有限公司 一种辅酶q10缓释软胶囊以及制备方法
CN116869971B (zh) * 2023-08-02 2024-04-05 广东润和生物科技有限公司 一种辅酶q10缓释软胶囊以及制备方法

Similar Documents

Publication Publication Date Title
US6451341B1 (en) Time release formulation of vitamins, minerals and other beneficial supplements
US6630157B1 (en) Therapeutic and dietary compositions containing essential fatty acids and bioactive disulphides
EP0514451B1 (fr) Complements alimentaires comprenant des vitamines et des sels mineraux
EP1275399B1 (fr) Préparation pour la prévention et/ou le traitement des maladies vasculaires et les maladies secondaires associées
US7195914B2 (en) Composition and method for treatment of hypertriglyceridemia
CA2657748C (fr) Produits pharmaceutiques et nutritceutiques comprenant de la vitamine k2
Patel The role of nutrition in the management of lower extremity wounds
PL190526B1 (pl) Leczniczo-odżywczy preparat dla osób chorych na cukrzycę
US20050233944A1 (en) Arginine compositions for coordinate modification of multiple cardiovascular risk factors
CA2291959A1 (fr) Composition nutraceutique de l-carnitine, d'ubiquinone, d'acides gras n-3 polyinsatures et de vitamines specialement formules en doses pharmacologiques pour ameliorer les elementsrelatifs aux facteurs de risque et aux symptomes de maladies reliees a l'atherosclerose
US20130064924A1 (en) Nutritional supplement for use under physiologically stressful conditions
US20060263446A1 (en) Formulations comprising multiple dietary and endogenously made antioxidants and B-vitamins and use of same
US20060009486A1 (en) Composition and method for treatment and prevention of coronary artery disease
Galland Nutrition and candidiasis
RU2228746C1 (ru) Антигиперлипидемическое средство (варианты)
CA2074527A1 (fr) Supplements alimentaires a base de vitamines et de mineraux
McColl Factors affecting the regulation of leukotriene production by neutrophils
MXPA00000793A (en) Therapeutic and dietary compositions containing essential fatty acids and bioactive disulphides

Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead