CA2291221A1 - 32 human secreted proteins - Google Patents

32 human secreted proteins Download PDF

Info

Publication number
CA2291221A1
CA2291221A1 CA002291221A CA2291221A CA2291221A1 CA 2291221 A1 CA2291221 A1 CA 2291221A1 CA 002291221 A CA002291221 A CA 002291221A CA 2291221 A CA2291221 A CA 2291221A CA 2291221 A1 CA2291221 A1 CA 2291221A1
Authority
CA
Canada
Prior art keywords
polypeptide
seq
sequence
cells
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002291221A
Other languages
English (en)
French (fr)
Inventor
Steven M. Ruben
Craig A. Rosen
Kenneth C. Carter
Patrick J. Dillon
Gregory A. Endress
Guo-Liang Yu
Jian Ni
Ping Feng
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2291221A1 publication Critical patent/CA2291221A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/525Tumour necrosis factor [TNF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/04Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002291221A 1997-05-30 1998-05-28 32 human secreted proteins Abandoned CA2291221A1 (en)

Applications Claiming Priority (19)

Application Number Priority Date Filing Date Title
US4809397P 1997-05-30 1997-05-30
US5093597P 1997-05-30 1997-05-30
US4403997P 1997-05-30 1997-05-30
US4810197P 1997-05-30 1997-05-30
US4819097P 1997-05-30 1997-05-30
US4835697P 1997-05-30 1997-05-30
US60/048,190 1997-05-30
US60/048,356 1997-05-30
US60/050,935 1997-05-30
US60/044,039 1997-05-30
US60/048,101 1997-05-30
US60/048,093 1997-05-30
US5629397P 1997-08-29 1997-08-29
US5625097P 1997-08-29 1997-08-29
US5629697P 1997-08-29 1997-08-29
US60/056,296 1997-08-29
US60/056,293 1997-08-29
US60/056,250 1997-08-29
PCT/US1998/010868 WO1998054206A1 (en) 1997-05-30 1998-05-28 32 human secreted proteins

Publications (1)

Publication Number Publication Date
CA2291221A1 true CA2291221A1 (en) 1998-12-03

Family

ID=27578175

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002291221A Abandoned CA2291221A1 (en) 1997-05-30 1998-05-28 32 human secreted proteins

Country Status (11)

Country Link
US (4) US6531447B1 (enExample)
EP (2) EP1015477B1 (enExample)
JP (1) JP2002512521A (enExample)
AT (1) ATE487737T1 (enExample)
AU (1) AU7801998A (enExample)
CA (1) CA2291221A1 (enExample)
CY (1) CY1111950T1 (enExample)
DE (1) DE69841994D1 (enExample)
DK (1) DK1015477T3 (enExample)
PT (1) PT1015477E (enExample)
WO (1) WO1998054206A1 (enExample)

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EP0837128A3 (en) * 1996-10-21 1999-04-28 Smithkline Beecham Corporation Human G-protein coupled receptor, HLYAZ61
EP0978519A4 (en) * 1997-04-18 2002-10-30 Chugai Pharmaceutical Co Ltd Transcriptional regulator
DK1015477T3 (da) * 1997-05-30 2011-02-07 Human Genome Sciences Inc 32 humane sekreterede proteiner
US7001992B2 (en) 1997-05-30 2006-02-21 Human Genome Sciences, Inc. Antibodies to secreted protein HEMCM42
WO2000011942A1 (en) * 1998-09-01 2000-03-09 Gene Logic, Inc. IDENTIFICATION OF A cDNA ASSOCIATED WITH ISCHEMIA IN HUMAN HEART TISSUE
CA2361293A1 (en) * 1999-02-10 2000-08-17 Human Genome Sciences, Inc. 33 human secreted proteins
US6372490B1 (en) * 1999-02-23 2002-04-16 Curagen Corporation Nucleic acid encoding the MDM interacting protein
FR2797447B1 (fr) * 1999-08-12 2004-04-02 Univ Clermont Auvergne "odorant-binding" proteines humaines fixant des ligands hydrophobes:polypeptides et polynucleotides codant lesdits polypeptides et leurs applications
JP2003512855A (ja) * 1999-10-29 2003-04-08 ヒューマン ジノーム サイエンシーズ, インコーポレイテッド 26個のヒト分泌タンパク質
EP1230255A4 (en) * 1999-10-29 2004-10-13 Human Genome Sciences Inc 25 PROTEINS SECRETED BY MAN
US6727225B2 (en) 1999-12-20 2004-04-27 Immunex Corporation TWEAK receptor
NZ520171A (en) 1999-12-20 2005-07-29 Immunex Corp Tweak receptor
EP1174502A1 (en) * 2000-07-18 2002-01-23 Schering Corporation Type 2 dendritic cell precursor derived coding nucleic acids and related compositions and methods
AU2003265235A1 (en) 2002-04-26 2003-12-19 Genetech, Inc. Non-affinity purification of proteins
AU2004259355B2 (en) 2003-07-24 2011-02-03 Amgen Inc. Compositions and methods relating to multimeric and oligomeric soluble fragments of the tweak receptor
AU2006214179A1 (en) 2005-02-17 2006-08-24 Biogen Idec Ma Inc. Treating neurological disorders
WO2006122187A2 (en) 2005-05-10 2006-11-16 Biogen Idec Ma Inc. Treating and evaluating inflammatory disorders
EP1876448A1 (en) * 2005-09-30 2008-01-09 DIGILAB BioVisioN GmbH Method and analytical reagents for identifying therapeutics using biomarkers responsive to thiazolidinediones.
PL2562182T3 (pl) * 2007-07-27 2016-03-31 Immatics Biotechnologies Gmbh Nowe immunogenne epitopy do immunoterapii
ES2411907T3 (es) 2007-08-03 2013-07-09 Facet Biotech Corporation Uso terapéutico de anticuerpos antirreceptor TWEAK
GB0809592D0 (en) * 2008-05-27 2008-07-02 Imp Innovations Ltd Biomaterials

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US912292A (en) * 1907-05-03 1909-02-16 Morris E Curtis Machine for making tubes.
US912293A (en) * 1908-02-03 1909-02-16 Nat Regulator Company Temperature-regulating device.
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US4263428A (en) 1978-03-24 1981-04-21 The Regents Of The University Of California Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
EP0052322B1 (de) 1980-11-10 1985-03-27 Gersonde, Klaus, Prof. Dr. Verfahren zur Herstellung von Lipid-Vesikeln durch Ultraschallbehandlung, Anwendung des Verfahrens und Vorrichtung zur Durchführung des Verfahrens
IE52535B1 (en) 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
US4485045A (en) 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
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DE3374837D1 (en) 1982-02-17 1988-01-21 Ciba Geigy Ag Lipids in the aqueous phase
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US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4544545A (en) 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
HUT35524A (en) 1983-08-02 1985-07-29 Hoechst Ag Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance
ATE59966T1 (de) 1983-09-26 1991-02-15 Ehrenfeld Udo Mittel und erzeugnis fuer die diagnose und therapie von tumoren sowie zur behandlung von schwaechen der zelligen und humoralen immunabwehr.
DE3474511D1 (en) 1983-11-01 1988-11-17 Terumo Corp Pharmaceutical composition containing urokinase
JPS6147500A (ja) 1984-08-15 1986-03-07 Res Dev Corp Of Japan キメラモノクロ−ナル抗体及びその製造法
EP0173494A3 (en) 1984-08-27 1987-11-25 The Board Of Trustees Of The Leland Stanford Junior University Chimeric receptors by dna splicing and expression
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
US4631211A (en) 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
WO1987001130A1 (en) 1985-08-15 1987-02-26 Stauffer Chemical Company Tryptophan producing microorganism
AU606320B2 (en) 1985-11-01 1991-02-07 International Genetic Engineering, Inc. Modular assembly of antibody genes, antibodies prepared thereby and use
US5128256A (en) 1987-01-12 1992-07-07 Stratagene DNA cloning vectors with in vivo excisable plasmids
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ES2120949T4 (es) 1990-06-28 2011-12-29 Sanofi-Aventis Deutschland Gmbh 50% Proteinas de fusión con porciones de inmunoglobulinas, su preparación y empleo.
IL111125A0 (en) * 1994-05-11 1994-12-29 Yeda Res & Dev Soluble oligomeric tnf/ngf super family ligand receptors and their use
CA2220123A1 (en) 1995-05-05 1996-11-07 Human Genome Sciences, Inc. Human chemokine beta-8, chemokine beta-1 and macrophage inflammatory protein-4
FR2741075B1 (fr) * 1995-11-15 1998-01-30 Rech De Pathologie Appliquee S Conjugues peptidiques, leur utilisation a titre de medicament et compositions les contenant
JP2001513626A (ja) 1997-02-12 2001-09-04 アボツト・ラボラトリーズ 疾患の治療及び診断のために有用なtnfファミリーのメンバー
DK1015477T3 (da) * 1997-05-30 2011-02-07 Human Genome Sciences Inc 32 humane sekreterede proteiner
JP2002512524A (ja) * 1997-06-03 2002-04-23 財団法人相模中央化学研究所 膜貫通ドメインを有するヒト蛋白質及びそれをコードするdna
US6051385A (en) * 1997-10-22 2000-04-18 The Regents Of The University Of Michigan Compositions and methods for identifying and testing therapeutics against HSV infection
WO1999061471A2 (en) 1998-05-29 1999-12-02 Incyte Pharmaceuticals, Inc. Human transmembrane proteins
NZ520171A (en) * 1999-12-20 2005-07-29 Immunex Corp Tweak receptor

Also Published As

Publication number Publication date
AU7801998A (en) 1998-12-30
CY1111950T1 (el) 2015-11-04
US20030195346A1 (en) 2003-10-16
JP2002512521A (ja) 2002-04-23
DK1015477T3 (da) 2011-02-07
ATE487737T1 (de) 2010-11-15
DE69841994D1 (de) 2010-12-23
EP1015477A1 (en) 2000-07-05
US20060147982A1 (en) 2006-07-06
WO1998054206A1 (en) 1998-12-03
EP1015477B1 (en) 2010-11-10
PT1015477E (pt) 2010-12-28
US6531447B1 (en) 2003-03-11
EP1015477A4 (en) 2004-05-26
US20070248593A1 (en) 2007-10-25
EP2332975A1 (en) 2011-06-15

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20150528