CA2288014A1 - Biodegradable compositions comprising poly(cycloaliphatic phosphoester) compounds, articles, and methods for using the same - Google Patents

Biodegradable compositions comprising poly(cycloaliphatic phosphoester) compounds, articles, and methods for using the same Download PDF

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Publication number
CA2288014A1
CA2288014A1 CA002288014A CA2288014A CA2288014A1 CA 2288014 A1 CA2288014 A1 CA 2288014A1 CA 002288014 A CA002288014 A CA 002288014A CA 2288014 A CA2288014 A CA 2288014A CA 2288014 A1 CA2288014 A1 CA 2288014A1
Authority
CA
Canada
Prior art keywords
agents
polymer composition
group
polymer
biologically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002288014A
Other languages
English (en)
French (fr)
Inventor
Wenbin Dang
Hai-Quan Mao
Irina Shipanova-Kadiyala
Kam W. Leong
Zhong Zhao
James P. English
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Corp of North America
School of Medicine of Johns Hopkins University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2288014A1 publication Critical patent/CA2288014A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G79/00Macromolecular compounds obtained by reactions forming a linkage containing atoms other than silicon, sulfur, nitrogen, oxygen, and carbon with or without the latter elements in the main chain of the macromolecule
    • C08G79/02Macromolecular compounds obtained by reactions forming a linkage containing atoms other than silicon, sulfur, nitrogen, oxygen, and carbon with or without the latter elements in the main chain of the macromolecule a linkage containing phosphorus
    • C08G79/04Phosphorus linked to oxygen or to oxygen and carbon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/18Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/06Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/924Material characteristic
CA002288014A 1997-04-30 1998-04-30 Biodegradable compositions comprising poly(cycloaliphatic phosphoester) compounds, articles, and methods for using the same Abandoned CA2288014A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US84134597A 1997-04-30 1997-04-30
US08/841,345 1997-04-30
PCT/US1998/009185 WO1998048859A1 (en) 1997-04-30 1998-04-30 Biodegradable compositions comprising poly(cycloaliphatic phosphoester) compounds, articles, and methods for using the same

Publications (1)

Publication Number Publication Date
CA2288014A1 true CA2288014A1 (en) 1998-11-05

Family

ID=25284634

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002288014A Abandoned CA2288014A1 (en) 1997-04-30 1998-04-30 Biodegradable compositions comprising poly(cycloaliphatic phosphoester) compounds, articles, and methods for using the same

Country Status (15)

Country Link
US (2) US6403675B1 (US06800672-20041005-C00004.png)
EP (1) EP0980269A1 (US06800672-20041005-C00004.png)
JP (1) JP2002500640A (US06800672-20041005-C00004.png)
KR (1) KR20010020432A (US06800672-20041005-C00004.png)
CN (1) CN1258221A (US06800672-20041005-C00004.png)
AU (1) AU749644B2 (US06800672-20041005-C00004.png)
BR (1) BR9809017A (US06800672-20041005-C00004.png)
CA (1) CA2288014A1 (US06800672-20041005-C00004.png)
HU (1) HUP0001299A3 (US06800672-20041005-C00004.png)
IL (1) IL132487A0 (US06800672-20041005-C00004.png)
NO (1) NO995301L (US06800672-20041005-C00004.png)
NZ (1) NZ501184A (US06800672-20041005-C00004.png)
PL (1) PL336596A1 (US06800672-20041005-C00004.png)
TR (1) TR199902693T2 (US06800672-20041005-C00004.png)
WO (1) WO1998048859A1 (US06800672-20041005-C00004.png)

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US6153212A (en) 1998-10-02 2000-11-28 Guilford Pharmaceuticals Inc. Biodegradable terephthalate polyester-poly (phosphonate) compositions, articles, and methods of using the same
EP1117441A2 (en) * 1998-10-02 2001-07-25 Guilford Pharmaceuticals Inc. Biodegradable terephthalate polyester-poly(phosphonate) and polyester-poly(phosphite) compositions, articles, and methods of using them
US6419709B1 (en) 1998-10-02 2002-07-16 Guilford Pharmaceuticals, Inc. Biodegradable terephthalate polyester-poly(Phosphite) compositions, articles, and methods of using the same
US6350464B1 (en) * 1999-01-11 2002-02-26 Guilford Pharmaceuticals, Inc. Methods for treating ovarian cancer, poly (phosphoester) compositions, and biodegradable articles for same
US6537585B1 (en) * 1999-03-26 2003-03-25 Guilford Pharmaceuticals, Inc. Methods and compositions for treating solid tumors
CN1196736C (zh) * 1999-04-07 2005-04-13 纳幕尔杜邦公司 具有降低的甲醛气味的聚缩醛树脂
US20040038948A1 (en) * 1999-12-07 2004-02-26 Uhrich Kathryn E. Therapeutic compositions and methods
WO2001068052A2 (en) * 2000-03-10 2001-09-20 Johns Hopkins University Phosphate based biodegradable polymers
US8088060B2 (en) 2000-03-15 2012-01-03 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
US9522217B2 (en) 2000-03-15 2016-12-20 Orbusneich Medical, Inc. Medical device with coating for capturing genetically-altered cells and methods for using same
US20070141107A1 (en) * 2000-03-15 2007-06-21 Orbusneich Medical, Inc. Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device
EP1299048A4 (en) * 2000-06-28 2005-09-28 Atul J Shukla BIODEGRADABLE VEHICLES AND SYSTEMS FOR DELIVERY OF BIOLOGICALLY ACTIVE SUBSTANCES
AU2001269961A1 (en) 2000-07-06 2002-01-21 Guilford Pharmaceuticals Improved polymers and polymerization processes
AU2001270310A1 (en) * 2000-07-07 2002-01-21 Guilford Pharmaceuticals Inc. Compositions for sustained release of antineoplastic taxanes, and methods of making and using the same
AU2001280597A1 (en) * 2000-07-17 2002-01-30 Guilford Pharmaceuticals Inc. Compositions for sustained release of analgesic agents, and methods of making and using the same
US20020198135A1 (en) * 2000-10-12 2002-12-26 Wenbin Dang Compositions for release of radiosensitizers, and methods of making and using the same
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GB0100624D0 (en) * 2001-01-10 2001-02-21 Vernalis Res Ltd Chemical compounds VII
US20030032675A1 (en) * 2001-02-15 2003-02-13 Franz G. Andrew Manufacture of thyroid hormone tablets having consistent active moiety amounts
US6555581B1 (en) 2001-02-15 2003-04-29 Jones Pharma, Inc. Levothyroxine compositions and methods
JP2004525109A (ja) * 2001-02-15 2004-08-19 キング・ファーマシューティカルズ・インコーポレイティッド 安定化された甲状腺ホルモン医薬組成物、及びその製法
US20030224047A1 (en) * 2001-02-15 2003-12-04 Franz G. Andrew Levothyroxine compositions and methods
US7345138B2 (en) * 2001-05-14 2008-03-18 Johns Hopkins Singapore Pte Ltd. Biodegradable polyphosphates for controlled release of bioactive substances
WO2003000776A1 (en) * 2001-05-14 2003-01-03 Johns Hopkins Singapore Pte Ltd Biodegradable polyphosphoramidates for controlled release of bioactive substances
CA2449978A1 (en) * 2001-06-15 2002-12-27 Johns Hopkins Singapore Pte Ltd Biofunctional fibers
US20030134892A1 (en) * 2001-07-19 2003-07-17 Wenbin Dang Compositions for treatment of head and neck cancers, and methods of making and using the same
US20030133903A1 (en) * 2001-07-19 2003-07-17 Wenbin Dang Compositions for treatment of prostate cancers and methods of making and using the same
US20030198671A1 (en) * 2001-08-10 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique plasma AUC properties
US20030190349A1 (en) * 2001-08-10 2003-10-09 Franz G. Andrew Methods of stabilizing pharmaceutical compositions
US20030180353A1 (en) * 2001-08-10 2003-09-25 Franz G. Andrew Stabilized pharmaceutical compositions
US20030198667A1 (en) * 2001-08-10 2003-10-23 Franz Andrew G. Methods of producing dispersible pharmaceutical compositions
US20030203967A1 (en) * 2001-08-14 2003-10-30 Franz G. Andrew Levothyroxine compositions having unique Tmax properties
US20030195253A1 (en) * 2001-08-14 2003-10-16 Franz G. Andrew Unadsorbed levothyroxine pharmaceutical compositions, methods of making and methods of administration
US20030198672A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique triidothyronine plasma AUC properties
US20030199587A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique Cmax properties
US20030165564A1 (en) * 2001-10-29 2003-09-04 Franz G. Andrew Levothyroxine compositions having unique triiodothyronine Tmax properties
AU2003202255A1 (en) * 2002-01-09 2003-07-30 Guilford Pharmaceuticals, Inc. Compositions for treatment of central nervous system neoplasms, and methods of making and using the same
PT1509256E (pt) * 2002-05-24 2009-10-15 Angiotech Int Ag Composições e métodos de revestimento de implantes médicos
US8313760B2 (en) 2002-05-24 2012-11-20 Angiotech International Ag Compositions and methods for coating medical implants
JP4184158B2 (ja) * 2003-06-05 2008-11-19 旭化成ケミカルズ株式会社 ホスホニトリル酸エステルの製造法
WO2005013810A2 (en) * 2003-08-07 2005-02-17 University Of Florida Biodegradable embolic agents
EP1687043A2 (en) * 2003-11-20 2006-08-09 Angiotech International Ag Electrical devices and anti-scarring agents
US20050209664A1 (en) * 2003-11-20 2005-09-22 Angiotech International Ag Electrical devices and anti-scarring agents
WO2005085312A1 (en) * 2004-03-03 2005-09-15 Commonwealth Scientific And Industrial Research Organisation Biocompatible polymer compositions for dual or multistaged curing
WO2005097833A1 (en) * 2004-04-05 2005-10-20 University Of Florida Research Foundation, Inc. Functionalized organic oligomers using homogeneous modification method for molecular binding
CN100408037C (zh) * 2005-02-03 2008-08-06 武汉大学 一种治疗骨髓炎的药物及制备方法
AU2005100176A4 (en) * 2005-03-01 2005-04-07 Gym Tv Pty Ltd Garbage bin clip
DE602007008125D1 (de) * 2006-10-31 2010-09-09 Surmodics Pharmaceuticals Inc Kugelförmige polymer-teilchen
CN101125916B (zh) * 2007-06-26 2010-06-23 天大药业(珠海)有限公司 一种生物降解聚合物及其制备方法和应用
US9387250B2 (en) 2013-03-15 2016-07-12 Rutgers, The State University Of New Jersey Therapeutic compositions for bone repair
MX2015013894A (es) * 2013-04-03 2015-12-11 Allertein Therapeutics Llc Composiciones de nanoparticulas novedosas.

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Also Published As

Publication number Publication date
US6403675B1 (en) 2002-06-11
NZ501184A (en) 2002-08-28
KR20010020432A (ko) 2001-03-15
WO1998048859A1 (en) 1998-11-05
NO995301D0 (no) 1999-10-29
JP2002500640A (ja) 2002-01-08
TR199902693T2 (xx) 2000-04-21
HUP0001299A3 (en) 2001-09-28
AU749644B2 (en) 2002-06-27
US6800672B2 (en) 2004-10-05
US20020137814A1 (en) 2002-09-26
IL132487A0 (en) 2001-03-19
PL336596A1 (en) 2000-07-03
NO995301L (no) 1999-12-30
CN1258221A (zh) 2000-06-28
AU7177198A (en) 1998-11-24
HUP0001299A2 (hu) 2001-05-28
BR9809017A (pt) 2002-01-02
EP0980269A1 (en) 2000-02-23

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Legal Events

Date Code Title Description
FZDE Discontinued