CA2283678A1 - 28 human secreted proteins - Google Patents

28 human secreted proteins Download PDF

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Publication number
CA2283678A1
CA2283678A1 CA002283678A CA2283678A CA2283678A1 CA 2283678 A1 CA2283678 A1 CA 2283678A1 CA 002283678 A CA002283678 A CA 002283678A CA 2283678 A CA2283678 A CA 2283678A CA 2283678 A1 CA2283678 A1 CA 2283678A1
Authority
CA
Canada
Prior art keywords
polypeptide
seq
sequence
cells
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002283678A
Other languages
English (en)
French (fr)
Inventor
Steven M. Ruben
Craig A. Rosen
Yi Li
Zhizhen Zeng
Hla Kyaw
Carrie L. Fischer
Haodong Li
Daniel R. Soppet
Reiner L. Gentz
Ying-Fei Wei
Paul A. Moore
Paul E. Young
John M. Greene
Ann M. Ferrie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2283678A1 publication Critical patent/CA2283678A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4718Cytokine-induced proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002283678A 1997-03-14 1998-03-12 28 human secreted proteins Abandoned CA2283678A1 (en)

Applications Claiming Priority (19)

Application Number Priority Date Filing Date Title
US4076297P 1997-03-14 1997-03-14
US4071097P 1997-03-14 1997-03-14
US4835797P 1997-05-30 1997-05-30
US4818997P 1997-05-30 1997-05-30
US5093497P 1997-05-30 1997-05-30
US4810097P 1997-05-30 1997-05-30
US4897097P 1997-06-06 1997-06-06
US60/048,970 1997-06-06
US5776597P 1997-09-05 1997-09-05
US6836897P 1997-12-19 1997-12-19
US60/048,100 1997-12-19
US60/048,189 1997-12-19
US60/040,710 1997-12-19
US60/050,934 1997-12-19
US60/057,765 1997-12-19
US60/068,368 1997-12-19
US60/040,762 1997-12-19
US60/048,357 1997-12-19
PCT/US1998/004858 WO1998040483A2 (en) 1997-03-14 1998-03-12 28 human secreted proteins

Publications (1)

Publication Number Publication Date
CA2283678A1 true CA2283678A1 (en) 1998-09-17

Family

ID=27578155

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002283678A Abandoned CA2283678A1 (en) 1997-03-14 1998-03-12 28 human secreted proteins

Country Status (6)

Country Link
US (1) US6448230B1 (enExample)
EP (1) EP0973892A2 (enExample)
JP (1) JP2001524814A (enExample)
AU (1) AU6552198A (enExample)
CA (1) CA2283678A1 (enExample)
WO (1) WO1998040483A2 (enExample)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6919433B2 (en) 1997-03-14 2005-07-19 Human Genome Sciences, Inc. Antibodies to protein HPMBQ91
US6951924B2 (en) * 1997-03-14 2005-10-04 Human Genome Sciences, Inc. Antibodies against secreted protein HTEBYII
JP2001524814A (ja) 1997-03-14 2001-12-04 ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド 28種類のヒト分泌タンパク質
EP0892053A3 (en) * 1997-07-14 1999-12-29 Smithkline Beecham Plc production of recombinant HPMBQ91 polypeptide and uses thereof
JP2001516009A (ja) * 1997-07-17 2001-09-25 ルードヴィッヒ インスティテュート フォー キャンサー リサーチ ガン関連核酸及びポリペプチド
US6410708B1 (en) 1997-11-21 2002-06-25 Genentech, Inc. Nucleic acids encoding A-33 related antigen polypeptides
AU9395998A (en) * 1997-09-17 1999-04-05 Genentech Inc. Compositions and methods for the treatment of immune related diseases
CA2302936A1 (en) * 1997-09-19 1999-04-01 Magainin Pharmaceuticals, Inc. Asthma associated factors as targets for treating atopic allergies including asthma and related disorders
US20030054463A1 (en) * 1997-10-24 2003-03-20 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US8088386B2 (en) 1998-03-20 2012-01-03 Genentech, Inc. Treatment of complement-associated disorders
US7282565B2 (en) 1998-03-20 2007-10-16 Genentech, Inc. PRO362 polypeptides
US8007798B2 (en) 1997-11-21 2011-08-30 Genentech, Inc. Treatment of complement-associated disorders
EP2014677A1 (en) * 1997-11-21 2009-01-14 Genentech, Inc. A-33 related antigens and their pharmacological uses
US7273726B2 (en) 1997-11-21 2007-09-25 Genentech, Inc. Compounds, compositions and methods for the treatment of diseases characterized by A-33 related antigens
US6686147B1 (en) 1998-07-15 2004-02-03 Ludwig Institute For Cancer Research Cancer associated antigens and uses therefor
AU6498499A (en) * 1998-09-17 2000-04-03 Genentech Inc. Compositions and methods for the treatment of immune related diseases
US6995251B1 (en) 1999-10-28 2006-02-07 Baylor Ovary-specific genes and proteins
JP2003512010A (ja) * 1998-10-28 2003-04-02 ベイラー カレッジ オブ メディスン 卵巣特異的遺伝子およびタンパク質
US7335737B2 (en) 1998-10-28 2008-02-26 Baylor College Of Medicine Ovary-specific genes and proteins
EP1141331B1 (en) 1998-12-16 2008-09-17 Novartis Vaccines and Diagnostics, Inc. HUMAN CYCLIN-DEPENDENT KINASE (hPNQALRE)
US6579715B1 (en) 1999-01-19 2003-06-17 Lexicon Genetics Incorporated Mammalian cortexin-like proteins and polynucleotides encoding the same
CA2361293A1 (en) * 1999-02-10 2000-08-17 Human Genome Sciences, Inc. 33 human secreted proteins
EE05497B1 (et) * 1999-03-11 2011-12-15 Rmf Dictagene S.A. Polüpeptiid, lahustuv CRAM-1 polüpeptiid, polünukleotiid ja antikeha
EP1159287A4 (en) * 1999-03-12 2003-11-05 Human Genome Sciences Inc 50 HUMAN SECRETED PROTEINS
WO2000058357A1 (en) * 1999-03-26 2000-10-05 Human Genome Sciences, Inc. 50 human secreted proteins
AU4010400A (en) * 1999-03-18 2000-10-04 Human Genome Sciences, Inc. 27 human secreted proteins
CA2368376A1 (en) * 1999-03-26 2000-10-05 Human Genome Sciences, Inc. 50 human secreted proteins
CA2368719A1 (en) * 1999-03-26 2000-10-05 Craig A. Rosen 50 human secreted proteins
JP2002543772A (ja) * 1999-04-09 2002-12-24 ヒューマン ジノーム サイエンシーズ, インコーポレイテッド 49個のヒト分泌タンパク質
CA2383828A1 (en) * 1999-06-07 2000-12-14 Human Genome Sciences, Inc. 26 human secreted proteins
EP1514933A1 (en) * 1999-07-08 2005-03-16 Research Association for Biotechnology Secretory protein or membrane protein
US7129338B1 (en) 1999-07-08 2006-10-31 Research Association For Biotechnology Secretory protein or membrane protein
AU6906800A (en) * 1999-08-17 2001-03-13 Incyte Genomics, Inc. Membrane associated proteins
EP1227149A4 (en) * 1999-10-27 2004-03-31 Takeda Chemical Industries Ltd New protein and its use
EP1230359A1 (en) * 1999-11-10 2002-08-14 Compugen Ltd. Chordin-like homologs
US7018810B1 (en) * 1999-12-07 2006-03-28 Amgen Inc. Chordin-like molecules and uses thereof
US20030068624A1 (en) * 2000-10-26 2003-04-10 Recipon Herve E. Compositions and methods relating to lung specific genes and proteins
US20050123990A1 (en) * 2001-09-26 2005-06-09 Incyte Corporation Membrane associated proteins
AU2003202542A1 (en) 2002-01-07 2003-07-24 Euroscreen S.A. Ligand for g-protein coupled receptor gpr43 and uses thereof
WO2003102136A2 (en) 2002-05-30 2003-12-11 Human Genome Sciences, Inc. Antibodies that specifically bind to neurokinin b
US7056685B1 (en) * 2002-11-05 2006-06-06 Amgen Inc. Receptor ligands and methods of modulating receptors
EP3141560A3 (en) 2008-05-06 2017-05-24 Genentech, Inc. Affinity matured crig variants

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5536637A (en) * 1993-04-07 1996-07-16 Genetics Institute, Inc. Method of screening for cDNA encoding novel secreted mammalian proteins in yeast
CA2153480A1 (en) * 1993-11-12 1995-06-01 Kenichi Matsubara Gene signature
US5707829A (en) * 1995-08-11 1998-01-13 Genetics Institute, Inc. DNA sequences and secreted proteins encoded thereby
JP2001524814A (ja) 1997-03-14 2001-12-04 ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド 28種類のヒト分泌タンパク質
AU5340399A (en) 1998-08-10 2000-03-06 Incyte Pharmaceuticals, Inc. Proteases and associated proteins

Also Published As

Publication number Publication date
WO1998040483A3 (en) 1998-11-19
WO1998040483A2 (en) 1998-09-17
EP0973892A2 (en) 2000-01-26
AU6552198A (en) 1998-09-29
US6448230B1 (en) 2002-09-10
JP2001524814A (ja) 2001-12-04

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued