CA2280181A1 - Activite anti-angiogenique amelioree des derives constamment charges d'hormones steroidiennes - Google Patents
Activite anti-angiogenique amelioree des derives constamment charges d'hormones steroidiennes Download PDFInfo
- Publication number
- CA2280181A1 CA2280181A1 CA002280181A CA2280181A CA2280181A1 CA 2280181 A1 CA2280181 A1 CA 2280181A1 CA 002280181 A CA002280181 A CA 002280181A CA 2280181 A CA2280181 A CA 2280181A CA 2280181 A1 CA2280181 A1 CA 2280181A1
- Authority
- CA
- Canada
- Prior art keywords
- group
- carbon atoms
- alkyl
- radical selected
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Cardiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Abstract
L'invention concerne l'utilisation d'agonistes ou d'antagonistes constamment chargés de stéroïdes comme compositions puissamment anti-angiogéniques, qui renferment comme principe actif un composé de formules générales I (médicament), II (anti-oestrogènes) ou III, dans lesquelles "médicament" est un agoniste ou un antagoniste des stéroïdes, un mélange agoniste-antagoniste ou un agoniste partiel, et les substituants sont tels que définis dans la spécification.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL12018497A IL120184A (en) | 1997-02-09 | 1997-02-09 | Pharmaceutical compositions comprising permanently charged derivatives of steroid agonists or antagonists for preventing angiogenesis |
IL120184 | 1997-02-09 | ||
US08/833,074 US6083990A (en) | 1997-04-02 | 1997-04-02 | Enhanced anti-angiogenic activity of permanently charged derivatives of steroid hormones |
US08/833,074 | 1997-04-02 | ||
PCT/US1998/002176 WO1998034583A2 (fr) | 1997-02-09 | 1998-02-04 | Activite anti-angiogenique amelioree des derives constamment charges d'hormones steroidiennes |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2280181A1 true CA2280181A1 (fr) | 1998-08-13 |
Family
ID=26323367
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002280181A Abandoned CA2280181A1 (fr) | 1997-02-09 | 1998-02-04 | Activite anti-angiogenique amelioree des derives constamment charges d'hormones steroidiennes |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0981337A4 (fr) |
JP (1) | JP2001511182A (fr) |
AU (1) | AU746007B2 (fr) |
CA (1) | CA2280181A1 (fr) |
WO (1) | WO1998034583A2 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR3046792B1 (fr) * | 2016-01-19 | 2018-02-02 | Les Laboratoires Servier | Nouveaux derives d'ammonium, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
EP3484463B1 (fr) * | 2016-08-19 | 2020-02-12 | The United States of America, as Represented by The Secretary, Department of Health and Human Services Office of Technology Transfer | Modulateurs sélectifs du récepteur des oestrogènes (serms) conférant une protection contre la dégénérescence des photorécepteurs |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2914561A (en) * | 1957-08-06 | 1959-11-24 | Wm S Merrell Co | Amine derivatives of triphenylethylene |
US2971001A (en) * | 1959-10-21 | 1961-02-07 | Wm S Merrell Co | Quaternary salts of triphenylethanols, -ethylenes, and -ethanes |
BE637389A (fr) * | 1962-09-13 | |||
EP0776661A1 (fr) * | 1992-10-27 | 1997-06-04 | Nippon Kayaku Kabushiki Kaisha | Préparation combiné d'un antiestrogène et d'un glucocorticoide pour le traitement des desordres autoimmunitaires |
US5650425A (en) * | 1994-04-04 | 1997-07-22 | Pharmos Corporation | Permanently ionic derivatives of steroid hormones and their antagonists |
-
1998
- 1998-02-04 WO PCT/US1998/002176 patent/WO1998034583A2/fr not_active Application Discontinuation
- 1998-02-04 EP EP98903921A patent/EP0981337A4/fr not_active Withdrawn
- 1998-02-04 JP JP53487698A patent/JP2001511182A/ja not_active Abandoned
- 1998-02-04 AU AU60562/98A patent/AU746007B2/en not_active Ceased
- 1998-02-04 CA CA002280181A patent/CA2280181A1/fr not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP0981337A4 (fr) | 2003-03-12 |
JP2001511182A (ja) | 2001-08-07 |
AU6056298A (en) | 1998-08-26 |
AU746007B2 (en) | 2002-04-11 |
WO1998034583A2 (fr) | 1998-08-13 |
EP0981337A2 (fr) | 2000-03-01 |
WO1998034583A3 (fr) | 1998-11-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Discontinued | ||
FZDE | Discontinued |
Effective date: 20070205 |