CA2277860C - Centrifuge apparatus for separating blood - Google Patents

Centrifuge apparatus for separating blood Download PDF

Info

Publication number
CA2277860C
CA2277860C CA002277860A CA2277860A CA2277860C CA 2277860 C CA2277860 C CA 2277860C CA 002277860 A CA002277860 A CA 002277860A CA 2277860 A CA2277860 A CA 2277860A CA 2277860 C CA2277860 C CA 2277860C
Authority
CA
Canada
Prior art keywords
piston
chamber
container
piston rod
cylindrical member
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002277860A
Other languages
English (en)
French (fr)
Other versions
CA2277860A1 (en
Inventor
Niels Erik Holm
Glenn A. Jorgensen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VIVOLUTION AS
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of CA2277860A1 publication Critical patent/CA2277860A1/en
Application granted granted Critical
Publication of CA2277860C publication Critical patent/CA2277860C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B13/00—Control arrangements specially designed for centrifuges; Program control of centrifuges
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0485—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with a displaceable piston in the centrifuge chamber
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Ecology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Centrifugal Separators (AREA)
  • External Artificial Organs (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
CA002277860A 1997-01-08 1998-01-08 Centrifuge apparatus for separating blood Expired - Fee Related CA2277860C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3405597P 1997-01-08 1997-01-08
US60/034,055 1997-01-08
PCT/US1998/000488 WO1998030331A1 (en) 1997-01-08 1998-01-08 Centrifuge apparatus for separating blood

Publications (2)

Publication Number Publication Date
CA2277860A1 CA2277860A1 (en) 1998-07-16
CA2277860C true CA2277860C (en) 2005-11-29

Family

ID=21874026

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002277860A Expired - Fee Related CA2277860C (en) 1997-01-08 1998-01-08 Centrifuge apparatus for separating blood

Country Status (9)

Country Link
US (1) US5849178A (https=)
EP (1) EP0951360A4 (https=)
JP (1) JP2001508869A (https=)
AU (1) AU721671B2 (https=)
BR (1) BR9806732A (https=)
CA (1) CA2277860C (https=)
IL (1) IL130727A (https=)
NZ (1) NZ336397A (https=)
WO (1) WO1998030331A1 (https=)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE348328T1 (de) * 1997-01-08 2007-01-15 Bristol Myers Squibb Co Vorrichtung und verfahren zur herstellung von aus blut oder plasma bestehenden lösungen bekannter konzentration
US20020086431A1 (en) * 2000-08-21 2002-07-04 Markham Walter Bruce Sample preparation and slide plating apparatus and method
US6495051B1 (en) * 2000-09-29 2002-12-17 Bristol-Myers Squibb Company Methods for preparing blood or plasma component solutions with improved concentrations
US20020144939A1 (en) * 2001-04-09 2002-10-10 Dolecek Victor D. Miniaturized blood centrifuge having side mounted motor with belt drive
US6790371B2 (en) * 2001-04-09 2004-09-14 Medtronic, Inc. System and method for automated separation of blood components
US6835316B2 (en) 2001-04-09 2004-12-28 Medtronic, Inc. Clam shell blood reservoir holder with index line
US6589155B2 (en) 2001-04-09 2003-07-08 Medtronic, Inc. Miniaturized blood centrifuge having side mounted motor with belt drive
US6605028B2 (en) 2001-04-09 2003-08-12 Medtronic, Inc. Blood centrifuge having integral heating to control cellular component temperature
US6612975B2 (en) 2001-04-09 2003-09-02 Medtronic, Inc. Blood centrifuge with an enhanced internal drive assembly
DE10134913C2 (de) * 2001-07-18 2003-06-26 Hiberna Ag Vorrichtung und Verfahren zur Blutpräparation
US6589153B2 (en) 2001-09-24 2003-07-08 Medtronic, Inc. Blood centrifuge with exterior mounted, self-balancing collection chambers
US7699767B2 (en) 2002-07-31 2010-04-20 Arryx, Inc. Multiple laminar flow-based particle and cellular separation with laser steering
US11243494B2 (en) 2002-07-31 2022-02-08 Abs Global, Inc. Multiple laminar flow-based particle and cellular separation with laser steering
EP3229240A1 (en) 2002-07-31 2017-10-11 Premium Genetics (UK) Limited System and method of sorting materials using holographic laser steering
US7118676B2 (en) * 2003-09-04 2006-10-10 Arryx, Inc. Multiple laminar flow-based particle and cellular separation with laser steering
JP5046645B2 (ja) * 2003-09-04 2012-10-10 アリックス インコーポレイテッド 血液や細胞等の液体混合物を構成成分に分離する方法、装置およびシステム。
CN100475317C (zh) * 2003-09-04 2009-04-08 阿尔利克斯公司 利用激光操纵进行基于多层流的颗粒和细胞分离
ITMI20031715A1 (it) * 2003-09-05 2005-03-06 Dideco Spa Dispositivo di comando nella raccolta differenziata dei
US7060018B2 (en) * 2003-09-11 2006-06-13 Cobe Cardiovascular, Inc. Centrifuge apparatus for processing blood
US7694828B2 (en) * 2005-04-27 2010-04-13 Biomet Manufacturing Corp. Method and apparatus for producing autologous clotting components
US7618361B2 (en) * 2005-09-01 2009-11-17 Wagner Development, Inc. Gas driven solids discharge and pumping piston for a centrifugal separator
US7405532B2 (en) * 2006-10-06 2008-07-29 Arcus Technology, Inc. Microstepper motor device and method of controlling the device
WO2010043113A1 (en) * 2008-10-13 2010-04-22 Inverness Medical Switzerland Gmbh Method for separating red blood cells from blood samples and use thereof
CN101750244B (zh) * 2008-10-13 2014-03-12 艾博生物医药(杭州)有限公司 一种分离血液样本中红细胞的方法以及运用
AU2009334385B2 (en) * 2008-12-29 2015-10-08 Wagner Development, Inc. Solids discharge centrifugal separator with disposable contact elements
US10908066B2 (en) 2010-11-16 2021-02-02 1087 Systems, Inc. Use of vibrational spectroscopy for microfluidic liquid measurement
US20220031925A1 (en) 2010-11-19 2022-02-03 Dsm Ip Assets B.V. Centrifuge
US8469871B2 (en) 2010-11-19 2013-06-25 Kensey Nash Corporation Centrifuge
US8556794B2 (en) 2010-11-19 2013-10-15 Kensey Nash Corporation Centrifuge
US8870733B2 (en) 2010-11-19 2014-10-28 Kensey Nash Corporation Centrifuge
US8394006B2 (en) 2010-11-19 2013-03-12 Kensey Nash Corporation Centrifuge
US8317672B2 (en) 2010-11-19 2012-11-27 Kensey Nash Corporation Centrifuge method and apparatus
EP2646069B1 (en) 2010-11-29 2016-03-02 Vivostat A/S Processor unit for processing and controlling a preparation of a blood sample and method thereof
US8961904B2 (en) 2013-07-16 2015-02-24 Premium Genetics (Uk) Ltd. Microfluidic chip
US11796449B2 (en) 2013-10-30 2023-10-24 Abs Global, Inc. Microfluidic system and method with focused energy apparatus
CA2938268A1 (en) 2014-01-31 2015-08-06 Dsm Ip Assets B.V. Adipose tissue processing centrifuge and methods of use
EP3259579B1 (en) 2015-02-19 2022-09-14 1087 Systems, Inc. Scanning infrared measurement system
KR101926710B1 (ko) * 2016-07-19 2018-12-07 이준석 원심 분리용 용기, 및 원심 분리용 용기 내의 물질 이동 방법
EP3796998A1 (en) 2018-05-23 2021-03-31 ABS Global, Inc. Systems and methods for particle focusing in microchannels
WO2020128561A1 (en) 2018-12-21 2020-06-25 Premium Genetics (Uk) Ltd. System and methods for sub-population identification
EP3955735B1 (en) 2019-04-18 2024-05-22 ABS Global, Inc. System and process for continuous addition of cryoprotectant
US11628439B2 (en) 2020-01-13 2023-04-18 Abs Global, Inc. Single-sheath microfluidic chip
EP4232601A4 (en) 2020-10-21 2024-10-09 ABS Global, Inc. METHODS AND SYSTEMS FOR PROCESSING GENETIC SAMPLES TO DETERMINE IDENTITY OR DETECT CONTAMINATION
JP7633402B2 (ja) 2020-11-23 2025-02-19 エイビーエス グローバル、インコーポレイテッド モジュール式フロー・サイトメトリ・システム及びサンプル処理方法
USD1118965S1 (en) 2021-11-12 2026-03-17 Abs Global, Inc. Flow cytometry device

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2536793A (en) * 1945-03-02 1951-01-02 Separator Ab Sealing device for centrifugal separators
US3073517A (en) * 1959-04-07 1963-01-15 Beckman Instruments Inc Continuous flow centrifuge apparatus and rotor therefor
US4151844A (en) * 1977-11-11 1979-05-01 Baxter Travenol Laboratories, Inc. Method and apparatus for separating whole blood into its components and for automatically collecting one component
US4828716A (en) * 1987-04-03 1989-05-09 Andronic Devices, Ltd. Apparatus and method for separating phases of blood
US5122284A (en) * 1990-06-04 1992-06-16 Abaxis, Inc. Apparatus and method for optically analyzing biological fluids
CN1091315A (zh) * 1992-10-08 1994-08-31 E·R·斯奎布父子公司 血纤维蛋白封闭剂组合物及其使用方法
CH687505A5 (fr) * 1993-01-29 1996-12-31 Elp Rochat Séparateur centrifuge pour fluides.
ZA948564B (en) * 1993-11-19 1995-07-26 Bristol Myers Squibb Co Liquid separation apparatus and method
US5505683A (en) * 1993-12-10 1996-04-09 Haemonetics Corporation Centrifuge bowl gripping apparatus having a retaining arm with a stationary jaw and a moveable jaw
DK0794824T3 (da) * 1994-12-02 2008-12-08 Vivolution As Fremgangmåde og apparat til adskillelse af fibrinmonomer fra blodplasma

Also Published As

Publication number Publication date
IL130727A (en) 2002-04-21
NZ336397A (en) 2001-01-26
AU5821198A (en) 1998-08-03
IL130727A0 (en) 2000-06-01
US5849178A (en) 1998-12-15
BR9806732A (pt) 2000-02-29
EP0951360A1 (en) 1999-10-27
CA2277860A1 (en) 1998-07-16
WO1998030331A1 (en) 1998-07-16
JP2001508869A (ja) 2001-07-03
AU721671B2 (en) 2000-07-13
EP0951360A4 (en) 2003-08-27

Similar Documents

Publication Publication Date Title
CA2277860C (en) Centrifuge apparatus for separating blood
US6099740A (en) Apparatus and methods for preparing blood or plasma component solutions of known concentration
US5738784A (en) Device for separating a blood component from blood or plasma
CA2206516C (en) Centrifuge reagent delivery system
US6387263B1 (en) Apparatus and methods for preparing plasma solutions from blood with improved separation of plasma
RU2133468C1 (ru) Устройство для разделения пробы жидкости, способ разделения пробы жидкости, способ разделения жидкости на два или большее число компонентов, кольцевой узел, способ отделения компонента крови от пробы жидкости, способ получения фибрин-мономера из крови
NZ300349A (en) Centrifuge for separating fibrous monomer from blood with annular filter
US5955026A (en) Detecting the thickness of fibrin polymer using an optical device
US6403328B1 (en) Method of measuring erythrocyte sedimentation rate (ESR) or plasma fibrinogen of a blood sample
EP1242157B1 (en) Methods for preparing blood or plasma component solutions with improved concentrations
MXPA99006284A (en) Centrifuge apparatus for separating blood
US6495051B1 (en) Methods for preparing blood or plasma component solutions with improved concentrations
MXPA99006281A (en) Apparatus and methods for preparing blood or plasma component solutions of known concentration
MXPA99006285A (en) A centrifuge apparatus with temperature control means
NZ507820A (en) Method for producing fibrin from fibrinogen by heating and subjecting to enzyme

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed
MKLA Lapsed

Effective date: 20100108