CA2271935A1 - Modulation d'interactions entre myosine et integrines - Google Patents
Modulation d'interactions entre myosine et integrines Download PDFInfo
- Publication number
- CA2271935A1 CA2271935A1 CA002271935A CA2271935A CA2271935A1 CA 2271935 A1 CA2271935 A1 CA 2271935A1 CA 002271935 A CA002271935 A CA 002271935A CA 2271935 A CA2271935 A CA 2271935A CA 2271935 A1 CA2271935 A1 CA 2271935A1
- Authority
- CA
- Canada
- Prior art keywords
- integrin
- myosin
- peptide
- agent
- beta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Landscapes
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La présente invention décrit une interaction directe entre la myosine et le domaine cytoplasmique de protéines membranaires, en particulier les domaines cytoplasmiques phosphorylés de la sous-unité .beta. d'intégrines. L'invention concerne des méthodes d'identification d'agents bloquant la liaison d'intégrine à la myosine; des méthodes d'utilisation d'agents bloquant la liaison d'intégrine à la myosine afin de moduler des procédés biologiques et pathologiques; et des agents bloquant la liaison assistée d'intégrine à la myosine, modulant ainsi le déplacement associé d'une cellule ou d'un composant cellulaire.
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3166596P | 1996-11-21 | 1996-11-21 | |
| US60/031,665 | 1996-11-21 | ||
| US4209397P | 1997-03-28 | 1997-03-28 | |
| US60/042,093 | 1997-03-28 | ||
| US97565397P | 1997-11-21 | 1997-11-21 | |
| PCT/US1997/022422 WO1998022500A2 (fr) | 1996-11-21 | 1997-11-21 | Modulation d'interactions entre myosine et integrines |
| US60/975,653 | 1997-11-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2271935A1 true CA2271935A1 (fr) | 1998-05-28 |
Family
ID=29715947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002271935A Abandoned CA2271935A1 (fr) | 1996-11-21 | 1997-11-21 | Modulation d'interactions entre myosine et integrines |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2271935A1 (fr) |
-
1997
- 1997-11-21 CA CA002271935A patent/CA2271935A1/fr not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |