CA2271179A1 - Procede pour surveiller et detecter des interactions entre de petites molecules et des biomolecules - Google Patents

Procede pour surveiller et detecter des interactions entre de petites molecules et des biomolecules Download PDF

Info

Publication number
CA2271179A1
CA2271179A1 CA 2271179 CA2271179A CA2271179A1 CA 2271179 A1 CA2271179 A1 CA 2271179A1 CA 2271179 CA2271179 CA 2271179 CA 2271179 A CA2271179 A CA 2271179A CA 2271179 A1 CA2271179 A1 CA 2271179A1
Authority
CA
Canada
Prior art keywords
biomolecules
awd
small molecule
interaction
immobilized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2271179
Other languages
English (en)
Inventor
Angel Manez
David Barfuss
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sensorchem International Corp
Original Assignee
Sensorchem International Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sensorchem International Corp filed Critical Sensorchem International Corp
Priority to CA 2271179 priority Critical patent/CA2271179A1/fr
Priority to CA002368315A priority patent/CA2368315A1/fr
Priority to PCT/CA2000/000504 priority patent/WO2000068419A2/fr
Priority to EP00924999A priority patent/EP1190093A2/fr
Priority to AU43880/00A priority patent/AU4388000A/en
Publication of CA2271179A1 publication Critical patent/CA2271179A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/02—Analysing fluids
    • G01N29/022—Fluid sensors based on microsensors, e.g. quartz crystal-microbalance [QCM], surface acoustic wave [SAW] devices, tuning forks, cantilevers, flexural plate wave [FPW] devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/02—Analysing fluids
    • G01N29/036—Analysing fluids by measuring frequency or resonance of acoustic waves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/02—Indexing codes associated with the analysed material
    • G01N2291/025—Change of phase or condition
    • G01N2291/0255—(Bio)chemical reactions, e.g. on biosensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/02—Indexing codes associated with the analysed material
    • G01N2291/025—Change of phase or condition
    • G01N2291/0256—Adsorption, desorption, surface mass change, e.g. on biosensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/04—Wave modes and trajectories
    • G01N2291/042—Wave modes
    • G01N2291/0422—Shear waves, transverse waves, horizontally polarised waves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/04—Wave modes and trajectories
    • G01N2291/042—Wave modes
    • G01N2291/0423—Surface waves, e.g. Rayleigh waves, Love waves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/04—Wave modes and trajectories
    • G01N2291/042—Wave modes
    • G01N2291/0426—Bulk waves, e.g. quartz crystal microbalance, torsional waves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/04—Wave modes and trajectories
    • G01N2291/042—Wave modes
    • G01N2291/0427—Flexural waves, plate waves, e.g. Lamb waves, tuning fork, cantilever

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Acoustics & Sound (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
CA 2271179 1999-05-05 1999-05-05 Procede pour surveiller et detecter des interactions entre de petites molecules et des biomolecules Abandoned CA2271179A1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA 2271179 CA2271179A1 (fr) 1999-05-05 1999-05-05 Procede pour surveiller et detecter des interactions entre de petites molecules et des biomolecules
CA002368315A CA2368315A1 (fr) 1999-05-05 2000-05-05 Appareil et procede permettant de controler et de detecter les interactions entre une petite molecule et une biomolecule
PCT/CA2000/000504 WO2000068419A2 (fr) 1999-05-05 2000-05-05 Appareil et procede permettant de controler et de detecter les interactions entre une petite molecule et une biomolecule
EP00924999A EP1190093A2 (fr) 1999-05-05 2000-05-05 Appareil et procede permettant de controler et de detecter les interactions entre une petite molecule et une biomolecule
AU43880/00A AU4388000A (en) 1999-05-05 2000-05-05 Apparatus and process for monitoring and detecting small molecule-biomolecule interactions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA 2271179 CA2271179A1 (fr) 1999-05-05 1999-05-05 Procede pour surveiller et detecter des interactions entre de petites molecules et des biomolecules

Publications (1)

Publication Number Publication Date
CA2271179A1 true CA2271179A1 (fr) 2000-11-05

Family

ID=4163522

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2271179 Abandoned CA2271179A1 (fr) 1999-05-05 1999-05-05 Procede pour surveiller et detecter des interactions entre de petites molecules et des biomolecules

Country Status (4)

Country Link
EP (1) EP1190093A2 (fr)
AU (1) AU4388000A (fr)
CA (1) CA2271179A1 (fr)
WO (1) WO2000068419A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7101669B2 (en) 2000-04-12 2006-09-05 Sensorchem International Corporation Enzyme-based regeneration of surface-attached nucleic acids

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7371563B2 (en) 2000-11-08 2008-05-13 Surface Logix, Inc. Peelable and resealable devices for biochemical assays
US7439056B2 (en) 2000-11-08 2008-10-21 Surface Logix Inc. Peelable and resealable devices for arraying materials
US6967074B2 (en) 2000-11-08 2005-11-22 Surface Logix, Inc. Methods of detecting immobilized biomolecules
US6803205B2 (en) 2000-11-08 2004-10-12 Surface Logix, Inc. Methods of measuring enzyme activity using peelable and resealable devices
US7001740B2 (en) 2000-11-08 2006-02-21 Surface Logix, Inc. Methods of arraying biological materials using peelable and resealable devices
US7351575B2 (en) 2000-11-08 2008-04-01 Surface Logix, Inc. Methods for processing biological materials using peelable and resealable devices
US20070292855A1 (en) * 2005-08-19 2007-12-20 Intel Corporation Method and CMOS-based device to analyze molecules and nanomaterials based on the electrical readout of specific binding events on functionalized electrodes
EP2102659B1 (fr) * 2006-12-13 2012-10-31 Biosensor Applications Sweden AB (Publ) Procede repetable en continu de detection d'antigenes dans un volume d'essai
CN101595387B (zh) * 2006-12-13 2014-01-29 生物传感器应用国际有限公司 在测试体积中测试抗原的连续可重复方法
WO2010127122A1 (fr) * 2009-04-29 2010-11-04 The Trustees Of Columbia University In The City Of New York Structure fbar-cmos monolithique telle que pour une détection de masse
US9255912B2 (en) 2009-04-29 2016-02-09 The Trustees Of Columbia University In The City Of New York Monolithic FBAR-CMOS structure such as for mass sensing
WO2014062936A1 (fr) 2012-10-17 2014-04-24 The Trustees Of Columbia University In The City Of New York Transistors à effet de champ à jonction à cmos intégré pour plates-formes bioélectroniques denses et à faible bruit
US10122345B2 (en) 2013-06-26 2018-11-06 The Trustees Of Columbia University In The City Of New York Co-integrated bulk acoustic wave resonators
JP6487190B2 (ja) 2014-11-21 2019-03-20 サントル ナショナル ドゥラ ルシェルシュ シヤンティフィック 分子検出システム
US10600952B2 (en) * 2016-05-20 2020-03-24 Pulmostics Limited Surface acoustic wave sensor coating
GB201709659D0 (en) * 2017-06-16 2017-08-02 Found For Res And Tech Hellas Imbb-Forth Detecting nucleic acids in impure samples with an acoustic wave sensor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4999284A (en) * 1988-04-06 1991-03-12 E. I. Du Pont De Nemours And Company Enzymatically amplified piezoelectric specific binding assay
US5501986A (en) * 1988-04-06 1996-03-26 E. I. Du Pont De Nemours And Company Piezoelectric specific binding assay with mass amplified reagents
US5374521A (en) * 1991-09-17 1994-12-20 Kipling; Arlin L. Acoustic reflection process for molecular sensing using a bulk acoustic wave quartz sensor
US5880552A (en) * 1997-05-27 1999-03-09 The United States Of America As Represented By The Secretary Of The Navy Diamond or diamond like carbon coated chemical sensors and a method of making same
US6169194B1 (en) * 1997-10-16 2001-01-02 Michael Thompson High surface density covalent immobilization of oligonucleotide monolayers using a 1-(thiotrifluoroacetato)-11-(trichlorososilyl)-undecane linker

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7101669B2 (en) 2000-04-12 2006-09-05 Sensorchem International Corporation Enzyme-based regeneration of surface-attached nucleic acids

Also Published As

Publication number Publication date
WO2000068419A3 (fr) 2001-12-27
AU4388000A (en) 2000-11-21
EP1190093A2 (fr) 2002-03-27
WO2000068419A2 (fr) 2000-11-16

Similar Documents

Publication Publication Date Title
CA2271179A1 (fr) Procede pour surveiller et detecter des interactions entre de petites molecules et des biomolecules
US6904786B2 (en) Method and apparatus for characterizing materials by using a mechanical resonator
US6393895B1 (en) Method and apparatus for characterizing materials by using a mechanical resonator
US20040126814A1 (en) Sensor having molecularly imprinted polymers
US7335336B1 (en) Sensor array using lateral field excited resonators
Kato et al. Resonance acoustic microbalance with naked-embedded quartz (RAMNE-Q) biosensor fabricated by microelectromechanical-system process
JP4083621B2 (ja) 振動子を用いた分析方法
KR101529169B1 (ko) Ｓａｗ 센서 디바이스
US7413892B2 (en) Systems and methods for molecular recognition
US20240033734A1 (en) Analyte depletion for sensor equilibration
JP2004340766A (ja) 化学物質検出装置
US7331232B2 (en) Measurement method and biosensor apparatus using resonator
Ogi et al. Replacement-free electrodeless quartz crystal microbalance biosensor using nonspecific-adsorption of streptavidin on quartz
Smith et al. The new era of SAW devices
EP1361428A2 (fr) Procédé et dispositif de caractérisation des matériaux par utilisation d'un résonateur mécanique
CA2368315A1 (fr) Appareil et procede permettant de controler et de detecter les interactions entre une petite molecule et une biomolecule
JP4180472B2 (ja) 質量センサ
Ogi et al. Wireless electrodeless piezomagnetic biosensor with an isolated nickel oscillator
da Silva Granja et al. Characterisation of particle-surface interactions via anharmonic acoustic transduction
JP2003315235A (ja) 分析方法
JP4158971B2 (ja) 質量センサ
EP1361429A2 (fr) Procédé et dispositif de caractérisation des matériaux par utilisation d'un résonateur mécanique
Lange et al. Surface acoustic wave biosensors for biomolecular interaction analysis
Mascini et al. Immunosensors based on piezoelectric crystal device
KR20100108866A (ko) Ｅ．ｔａｒｄａ 항체가 형성된 미세질량센서 및 그 제조방법

Legal Events

Date Code Title Description
FZDE Dead