CA2269764A1 - Compositions and methods in which bis(biguanides) provide enhanced antimicrobial efficacy for disinfecting contact lenses - Google Patents

Compositions and methods in which bis(biguanides) provide enhanced antimicrobial efficacy for disinfecting contact lenses Download PDF

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Publication number
CA2269764A1
CA2269764A1 CA002269764A CA2269764A CA2269764A1 CA 2269764 A1 CA2269764 A1 CA 2269764A1 CA 002269764 A CA002269764 A CA 002269764A CA 2269764 A CA2269764 A CA 2269764A CA 2269764 A1 CA2269764 A1 CA 2269764A1
Authority
CA
Canada
Prior art keywords
carbon atoms
solution
group
lens
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002269764A
Other languages
English (en)
French (fr)
Inventor
Susan P. Spooner
David J. Heiler
Lisa C. Simpson
David A. Marsh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bausch and Lomb Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2269764A1 publication Critical patent/CA2269764A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
    • A01N47/44—Guanidine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
    • A61L12/141—Biguanides, e.g. chlorhexidine
    • A61L12/142—Polymeric biguanides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Agronomy & Crop Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Detergent Compositions (AREA)
  • Eyeglasses (AREA)
CA002269764A 1996-11-13 1997-11-04 Compositions and methods in which bis(biguanides) provide enhanced antimicrobial efficacy for disinfecting contact lenses Abandoned CA2269764A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3164696P 1996-11-13 1996-11-13
US60/031,646 1996-11-13
PCT/US1997/020087 WO1998020738A1 (en) 1996-11-13 1997-11-04 Compositions and methods in which bis(biguanides) provide enhanced antimicrobial efficacy for disinfecting contact lenses

Publications (1)

Publication Number Publication Date
CA2269764A1 true CA2269764A1 (en) 1998-05-22

Family

ID=21860642

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002269764A Abandoned CA2269764A1 (en) 1996-11-13 1997-11-04 Compositions and methods in which bis(biguanides) provide enhanced antimicrobial efficacy for disinfecting contact lenses

Country Status (7)

Country Link
EP (1) EP0942653A1 (pt)
JP (1) JP2001504246A (pt)
KR (1) KR20000053221A (pt)
AU (1) AU5429198A (pt)
BR (1) BR9713049A (pt)
CA (1) CA2269764A1 (pt)
WO (1) WO1998020738A1 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU739900B2 (en) * 1996-11-13 2001-10-25 Bausch & Lomb Incorporated Disinfecting contact lenses with bis(biguanides) and polymeric biguanides
ID25783A (id) * 1997-11-12 2000-11-02 Bausch & Lomb Pembasmian kumam pada lensa kontak dengan bis (guanida) dan biguanida polimerik
BR9814012A (pt) * 1997-11-12 2000-09-26 Bausch & Lomb Desinfecção de lentes de contato com poliquatérnios e biguanidas poliméricas.
US6369112B1 (en) 1998-12-15 2002-04-09 Bausch & Lomb Incorporated Treatment of contact lenses with aqueous solution comprising a biguanide disinfectant stabilized by tyloxapol
US6309596B1 (en) * 1998-12-15 2001-10-30 Bausch & Lomb Incorporated Treatment of contact lenses with aqueous solution comprising a biguanide disinfectant stabilized by a poloxamine
AU2195800A (en) 1998-12-18 2000-07-03 Alcon Laboratories, Inc. Bis-amido polybiguanides and the use thereof to disinfect contact lenses and preserve pharmaceutical compositions
JP2002532463A (ja) 1998-12-18 2002-10-02 アルコン ラボラトリーズ，インコーポレイテッド アミドポリビグアニドとその抗微生物剤への使用
US6634748B1 (en) * 2000-11-15 2003-10-21 Johnson & Johnson Vision Care, Inc. Methods of stabilizing silicone hydrogels against hydrolytic degradation
US20040204496A1 (en) * 2003-04-11 2004-10-14 Ammon Daniel M. Disinfecting solutions effective against bacterial endospores
US20060067981A1 (en) * 2004-09-29 2006-03-30 Bausch & Lomb Incorporated Contact lens with improved biocidal activity and related methods and materials
US7897553B2 (en) * 2006-10-23 2011-03-01 Bausch & Lomb Incorporated Biguanide composition with low terminal amine
IL190181A (en) 2008-03-16 2015-08-31 Altos Medical Llc Cleaning, sanitizing and sterilizing products
WO2014060755A1 (en) 2012-10-17 2014-04-24 Arcis Biotechnology Holdings Limited Cleaning, sanitizing and sterilizing preparations
CN105010379B (zh) * 2014-04-30 2018-06-01 宁波润增医疗科技有限公司 杀菌剂及其应用
EP3417885B1 (en) * 2016-02-17 2022-12-07 Seed Co., Ltd. Anti-acanthamoeba solvent for contact lenses
CN110121548A (zh) * 2017-01-03 2019-08-13 陈煌兴 支化聚合双胍化合物及其用途
CN110078913B (zh) * 2019-05-29 2021-08-24 湖南雪天精细化工股份有限公司 一种聚六亚甲基双胍盐酸盐的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8312663D0 (en) * 1983-05-09 1983-06-15 Ici Plc Bisbiguanide compounds
CA2009118C (en) * 1989-02-21 1996-02-27 Mary F. Mowrey-Mckee Method and composition for cleaning and disinfecting contact lenses
US4891423A (en) * 1989-03-20 1990-01-02 Stockel Richard F Polymeric biguanides
EP0690728B1 (en) * 1993-01-07 1998-11-25 Polymer Technology Corporation Preservative system for contact lens solutions

Also Published As

Publication number Publication date
BR9713049A (pt) 2000-04-04
EP0942653A1 (en) 1999-09-22
AU5429198A (en) 1998-06-03
KR20000053221A (ko) 2000-08-25
JP2001504246A (ja) 2001-03-27
WO1998020738A1 (en) 1998-05-22

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US6369112B1 (en) Treatment of contact lenses with aqueous solution comprising a biguanide disinfectant stabilized by tyloxapol
US6309596B1 (en) Treatment of contact lenses with aqueous solution comprising a biguanide disinfectant stabilized by a poloxamine
CA2269764A1 (en) Compositions and methods in which bis(biguanides) provide enhanced antimicrobial efficacy for disinfecting contact lenses
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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued
FZDE Discontinued

Effective date: 20011105