CA2268069A1 - Diagnostic detection of nucleic acids - Google Patents
Diagnostic detection of nucleic acids Download PDFInfo
- Publication number
- CA2268069A1 CA2268069A1 CA002268069A CA2268069A CA2268069A1 CA 2268069 A1 CA2268069 A1 CA 2268069A1 CA 002268069 A CA002268069 A CA 002268069A CA 2268069 A CA2268069 A CA 2268069A CA 2268069 A1 CA2268069 A1 CA 2268069A1
- Authority
- CA
- Canada
- Prior art keywords
- nucleic acid
- seq
- sequences
- sequence
- target human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Virology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2676296P | 1996-10-04 | 1996-10-04 | |
| US60/026,762 | 1996-10-04 | ||
| PCT/US1997/017880 WO1998014617A1 (en) | 1996-10-04 | 1997-10-03 | Diagnostic detection of nucleic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2268069A1 true CA2268069A1 (en) | 1998-04-09 |
Family
ID=21833653
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002268069A Abandoned CA2268069A1 (en) | 1996-10-04 | 1997-10-03 | Diagnostic detection of nucleic acids |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US6344317B2 (https=) |
| EP (1) | EP0960210A4 (https=) |
| JP (1) | JP4044142B2 (https=) |
| AU (1) | AU4667297A (https=) |
| CA (1) | CA2268069A1 (https=) |
| WO (1) | WO1998014617A1 (https=) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8043835B1 (en) | 1996-03-26 | 2011-10-25 | Oncomedx, Inc. | Methods for detecting and monitoring cancer using extracellular RNA |
| US6759217B2 (en) * | 1996-03-26 | 2004-07-06 | Oncomedx, Inc. | Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer |
| ATE471150T1 (de) * | 1996-03-26 | 2010-07-15 | Kopreski Michael S | Methoden aus plasma oder serum extrahierte extrazelluraere rna zur diagnoseüberwachung oder evaluation von krebs verwenden |
| US7785842B2 (en) * | 1996-03-26 | 2010-08-31 | Oncomedx, Inc. | Comparative analysis of extracellular RNA species |
| US8440396B2 (en) * | 1997-03-14 | 2013-05-14 | Oncomedx, Inc. | Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer |
| US20070009934A1 (en) * | 1997-03-14 | 2007-01-11 | Kopreski Michael S | Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer |
| US8163524B2 (en) * | 1998-09-22 | 2012-04-24 | Oncomedx, Inc. | Comparative analysis of extracellular RNA species |
| US20090233276A1 (en) * | 1998-09-22 | 2009-09-17 | Oncomedx, Inc. | Method Enabling the Use of Extracellular Ribonucleic Acid (RNA) Extracted from Plasma or Serum to Detect, Monitor or Evaluate Cancer or Premalignant Conditions |
| US20060204989A1 (en) * | 1998-09-22 | 2006-09-14 | Kopreski Michael S | Comparative analysis of extracellular RNA species |
| CA2443170A1 (en) * | 2001-03-30 | 2002-10-10 | Chronix Biomedical, Inc. | Diagnostic detection of nucleic acids |
| US20040161741A1 (en) | 2001-06-30 | 2004-08-19 | Elazar Rabani | Novel compositions and processes for analyte detection, quantification and amplification |
| US9777312B2 (en) | 2001-06-30 | 2017-10-03 | Enzo Life Sciences, Inc. | Dual polarity analysis of nucleic acids |
| DE60239470D1 (de) * | 2001-07-25 | 2011-04-28 | Oncomedx Inc | Verfahren zur bewertung pathologischer krankheitszustände unter verwendung extrazellulärer rna |
| US20100159464A1 (en) * | 2001-11-05 | 2010-06-24 | Oncomedx, Inc. | Method for Detection of DNA Methyltransferase RNA in Plasma and Serum |
| US20030104454A1 (en) * | 2001-11-05 | 2003-06-05 | Kopreski Michael S. | Method for detection of DNA methyltransferase RNA in plasma and serum |
| WO2003044215A2 (en) | 2001-11-20 | 2003-05-30 | Oncomedx, Inc. | Methods for evaluating drug-resistance gene expression in the cancer patient |
| US7022478B2 (en) | 2002-05-14 | 2006-04-04 | The Chinese University Of Hong Kong | Methods for evaluating stroke or cardiac ischemia by nucleic acid detection |
| US20060099621A1 (en) * | 2004-10-07 | 2006-05-11 | Chronix Biomedical | Detection of nucleic acids to assess risk for Creutzfeldt-Jakob disease |
| WO2007044727A2 (en) | 2005-10-07 | 2007-04-19 | California Institute Of Technology | Pkr activation via hybridization chain reaction |
| US7798645B2 (en) | 2006-05-16 | 2010-09-21 | Mark Costin Roser | Visual and memory stimulating retina self-monitoring system |
| WO2008144562A1 (en) | 2007-05-16 | 2008-11-27 | California Institute Of Technology | A versatile nucleic acid hairpin motif for programming biomolecular self-assembly pathways |
| US20090136942A1 (en) * | 2007-09-18 | 2009-05-28 | Oncomedx, Inc. | Analysis of Extracellular RNA |
| US9518097B2 (en) * | 2007-11-09 | 2016-12-13 | Board Of Trustees Of Michigan State University | Identification and use of genes encoding amatoxin and phallotoxin |
| US9273100B2 (en) | 2007-11-09 | 2016-03-01 | Board Of Trustees Of Michigan State University | Use of Galerina marginata genes and proteins for peptide production |
| WO2009131728A2 (en) * | 2008-01-29 | 2009-10-29 | Ibis Biosciences, Inc. | Compositions for use in identification of picornaviruses |
| US9332973B2 (en) | 2008-10-01 | 2016-05-10 | Covidien Lp | Needle biopsy device with exchangeable needle and integrated needle protection |
| US8968210B2 (en) * | 2008-10-01 | 2015-03-03 | Covidien LLP | Device for needle biopsy with integrated needle protection |
| US9782565B2 (en) | 2008-10-01 | 2017-10-10 | Covidien Lp | Endoscopic ultrasound-guided biliary access system |
| US11298113B2 (en) | 2008-10-01 | 2022-04-12 | Covidien Lp | Device for needle biopsy with integrated needle protection |
| US9186128B2 (en) | 2008-10-01 | 2015-11-17 | Covidien Lp | Needle biopsy device |
| DE102009004269A1 (de) | 2009-01-07 | 2010-07-08 | Beiersdorf Ag | Diole als antitranspirantwirksames Mittel |
| US8962241B2 (en) * | 2010-07-20 | 2015-02-24 | California Institute Of Technology | Triggered molecular geometry based bioimaging probes |
| US9834439B2 (en) | 2010-07-20 | 2017-12-05 | California Institute Of Technology | Biomolecular self-assembly |
| MX2014014356A (es) | 2012-05-24 | 2015-07-06 | Fundació Inst D Investigació Biomédica De Bellvitge Idibell | Metodo para la identificacion del origen de un cancer de origen primario desconocido. |
| EP2931922B1 (en) * | 2012-12-14 | 2018-10-17 | Chronix Biomedical | Personalized biomarkers for cancer |
| US9856472B2 (en) | 2013-07-01 | 2018-01-02 | California Institute Of Technology | Small conditional RNAs |
| US9984201B2 (en) | 2015-01-18 | 2018-05-29 | Youhealth Biotech, Limited | Method and system for determining cancer status |
| US10202650B2 (en) | 2016-05-31 | 2019-02-12 | Youhealth Biotech, Limited | Methods for monitoring ELOVL2, KLF14 and PENK gene expression following treatment with vitamin C |
| IL324487A (en) | 2016-07-05 | 2026-01-01 | California Inst Of Techn | Hybridization chain reaction based on a minimal initiator |
| EP3481941A4 (en) | 2016-07-06 | 2020-04-15 | Youhealth Biotech, Limited | METHYLIZATION MARKERS FOR BREAST AND OVARIAL CANCER AND THEIR USE |
| WO2018009705A1 (en) | 2016-07-06 | 2018-01-11 | Youhealth Biotech, Limited | Liver cancer methylation markers and uses thereof |
| EP3481403B1 (en) | 2016-07-06 | 2022-02-09 | Youhealth Biotech, Limited | Solid tumor methylation markers and uses thereof |
| US10093986B2 (en) | 2016-07-06 | 2018-10-09 | Youhealth Biotech, Limited | Leukemia methylation markers and uses thereof |
| WO2018009696A1 (en) | 2016-07-06 | 2018-01-11 | Youhealth Biotech, Limited | Colon cancer methylation markers and uses thereof |
| CA3034617A1 (en) | 2016-08-30 | 2018-03-08 | California Institute Of Technology | Immunohistochemistry via hybridization chain reaction |
| BR112019018272A2 (pt) | 2017-03-02 | 2020-07-28 | Youhealth Oncotech, Limited | marcadores metilação para diagnosticar hepatocelular carcinoma e câncer |
| CN117339219A (zh) | 2017-04-10 | 2024-01-05 | 安可合伙人公司 | 高尔夫系统 |
| US12404540B2 (en) | 2018-10-17 | 2025-09-02 | The University Of Queensland | Epigenetic biomarker and uses therefor |
| EP4100955A4 (en) * | 2020-02-06 | 2024-02-28 | Oncohost Ltd | MACHINE LEARNING PREDICTION OF THERAPEUTIC RESPONSE |
| US11873485B2 (en) | 2021-01-26 | 2024-01-16 | California Institute Of Technology | Allosteric conditional guide RNAs for cell-selective regulation of CRISPR/Cas |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4965189A (en) | 1986-07-01 | 1990-10-23 | University Of Massachusetts Medical School | Probes for the determination of the proclivity for development of autoimmune diseases |
| ATE198358T1 (de) * | 1992-04-27 | 2001-01-15 | Dartmouth College | Detektion von gensequenzen in biologischen flüssigkeiten |
| US5242657A (en) * | 1992-07-02 | 1993-09-07 | Waukesha Foundry, Inc. | Lead-free corrosion resistant copper-nickel alloy |
| CA2092455A1 (en) * | 1993-03-25 | 1994-09-26 | Johanna M. Rommens | Process for isolating genes and the gene causative of huntington disease |
| US5405577A (en) * | 1993-04-29 | 1995-04-11 | Seelig; Karl F. | Lead-free and bismuth-free tin alloy solder composition |
| US5352407A (en) * | 1993-04-29 | 1994-10-04 | Seelig Karl F | Lead-free bismuth free tin alloy solder composition |
| US5455044A (en) | 1993-05-14 | 1995-10-03 | Depotech Corporation | Method for treating neurological disorders |
| US5411703A (en) * | 1993-06-16 | 1995-05-02 | International Business Machines Corporation | Lead-free, tin, antimony, bismtuh, copper solder alloy |
| US5393489A (en) * | 1993-06-16 | 1995-02-28 | International Business Machines Corporation | High temperature, lead-free, tin based solder composition |
| US5410184A (en) * | 1993-10-04 | 1995-04-25 | Motorola | Microelectronic package comprising tin-copper solder bump interconnections, and method for forming same |
| US5435968A (en) * | 1994-01-21 | 1995-07-25 | Touchstone, Inc. | A lead-free solder composition |
| US5639600A (en) * | 1994-08-05 | 1997-06-17 | The Regents Of The University Of California | Diagnosis and treatment of cell proliferative disease having clonal macrophage involvement |
| JP2805595B2 (ja) * | 1994-11-02 | 1998-09-30 | 三井金属鉱業株式会社 | 鉛無含有半田合金 |
| FR2737500B1 (fr) * | 1995-08-03 | 1997-08-29 | Bio Merieux | Materiel viral et fragments nucleotidiques associes a la sclerose en plaques, a des fins de diagnostic, prophylactiques et therapeutiques |
| GB9518154D0 (en) * | 1995-09-06 | 1995-11-08 | Lynxvale Ltd | Oligonucleotides and their use |
| JPH09155587A (ja) * | 1995-11-30 | 1997-06-17 | Mitsui Mining & Smelting Co Ltd | 錫−亜鉛系無鉛半田合金 |
| ATE471150T1 (de) * | 1996-03-26 | 2010-07-15 | Kopreski Michael S | Methoden aus plasma oder serum extrahierte extrazelluraere rna zur diagnoseüberwachung oder evaluation von krebs verwenden |
| US5837191A (en) * | 1996-10-22 | 1998-11-17 | Johnson Manufacturing Company | Lead-free solder |
| US5863493A (en) * | 1996-12-16 | 1999-01-26 | Ford Motor Company | Lead-free solder compositions |
-
1997
- 1997-10-03 JP JP51690698A patent/JP4044142B2/ja not_active Expired - Fee Related
- 1997-10-03 CA CA002268069A patent/CA2268069A1/en not_active Abandoned
- 1997-10-03 AU AU46672/97A patent/AU4667297A/en not_active Abandoned
- 1997-10-03 EP EP97945474A patent/EP0960210A4/en not_active Withdrawn
- 1997-10-03 US US08/943,607 patent/US6344317B2/en not_active Expired - Lifetime
- 1997-10-03 WO PCT/US1997/017880 patent/WO1998014617A1/en not_active Ceased
-
2001
- 2001-09-19 US US09/957,215 patent/US20030077588A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU4667297A (en) | 1998-04-24 |
| EP0960210A4 (en) | 2004-06-09 |
| US6344317B2 (en) | 2002-02-05 |
| JP2001507213A (ja) | 2001-06-05 |
| US20010014445A1 (en) | 2001-08-16 |
| EP0960210A1 (en) | 1999-12-01 |
| JP4044142B2 (ja) | 2008-02-06 |
| WO1998014617A1 (en) | 1998-04-09 |
| US20030077588A1 (en) | 2003-04-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |