CA2264870C - Appareil permettant de caracteriser les tissus de visceres epitheliales tapissees - Google Patents

Appareil permettant de caracteriser les tissus de visceres epitheliales tapissees Download PDF

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Publication number
CA2264870C
CA2264870C CA002264870A CA2264870A CA2264870C CA 2264870 C CA2264870 C CA 2264870C CA 002264870 A CA002264870 A CA 002264870A CA 2264870 A CA2264870 A CA 2264870A CA 2264870 C CA2264870 C CA 2264870C
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CA
Canada
Prior art keywords
probe
tissue
bers
uorescence
under test
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002264870A
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English (en)
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CA2264870A1 (fr
Inventor
Rebecca Richards-Kortum
Michele Follen Mitchell
Urs Utzinger
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University of Texas System
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University of Texas System
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Publication date
Application filed by University of Texas System filed Critical University of Texas System
Publication of CA2264870A1 publication Critical patent/CA2264870A1/fr
Application granted granted Critical
Publication of CA2264870C publication Critical patent/CA2264870C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Endoscopes (AREA)

Abstract

Cette invention concerne un procédé et un appareil permettant de caractériser in vivo les tissus de viscères épithéliales tapissées, y compris le canal endocervical, entre autres. Ce procédé consiste à illuminer la surface interne des viscères à l'aide de longueurs d'ondes de rayonnements électromagnétiques, ceci de manière produire plusieurs spectres à intensité de fluorescence. On mesure ensuite plusieurs longueurs d'ondes d'émission provenant des spectres à intensité de fluorescence, après quoi on caractérise les tissus des viscères épithéliales en fonction ces longueurs d'ondes d'émission. L'appareil décrit dans cette invention comprend les éléments suivants: une source lumineuse (17, 18) qui va émettre plusieurs longueurs d'ondes de rayonnements électromagnétiques; une sonde optique (11) connectée à la source lumineuse, laquelle sonde (11) va appliquer les longueurs d'ondes de rayonnements électromagnétiques à la surface interne des tissus des viscères épithéliales testés, puis collecter la fluorescence émise par les tissus; un détecteur (24, 26) qui est connecté à la sonde et qui va mesurer au moins un spectre de fluorescence émis par les tissus testés; et enfin, un ordinateur programmé (29) qui est connecté au détecteur et qui va traiter le ou les spectres de fluorescence en fonction d'un algorithme prédéterminé afin de caractériser les tissus testés.
CA002264870A 1996-08-02 1997-07-31 Appareil permettant de caracteriser les tissus de visceres epitheliales tapissees Expired - Fee Related CA2264870C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US69347196A 1996-08-02 1996-08-02
US08/693471 1996-08-02
PCT/US1997/013300 WO1998005253A1 (fr) 1996-08-02 1997-07-31 Procede et appareil permettant de caracteriser les tissus de visceres epitheliales tapissees

Publications (2)

Publication Number Publication Date
CA2264870A1 CA2264870A1 (fr) 1998-02-12
CA2264870C true CA2264870C (fr) 2005-07-26

Family

ID=24784792

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002264870A Expired - Fee Related CA2264870C (fr) 1996-08-02 1997-07-31 Appareil permettant de caracteriser les tissus de visceres epitheliales tapissees

Country Status (4)

Country Link
EP (1) EP0925015A1 (fr)
JP (2) JP2000515407A (fr)
CA (1) CA2264870C (fr)
WO (1) WO1998005253A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19925210C2 (de) * 1999-06-01 2001-12-20 Alexander Hohla Fasersonde
US20030125630A1 (en) 2001-12-31 2003-07-03 Furnish Simon M. Catheter probe arrangement for tissue analysis by radiant energy delivery and radiant energy collection
US7647092B2 (en) 2002-04-05 2010-01-12 Massachusetts Institute Of Technology Systems and methods for spectroscopy of biological tissue
JP4588324B2 (ja) * 2002-04-05 2010-12-01 マサチユセツツ・インスチチユート・オブ・テクノロジイ 組織測定用プローブ
US20040010185A1 (en) * 2002-07-11 2004-01-15 Optical Sensors, Inc. Method for measuring a physiologic parameter using a preferred site
EP1601288B1 (fr) * 2003-03-05 2012-05-09 InfraReDx, Inc. Agencement de sonde de catheter pour l'analyse de tissus par application d'energie rayonnante et par collecte d'energie rayonnante
JP4668624B2 (ja) * 2005-01-07 2011-04-13 オリンパス株式会社 食道粘膜用画像処理装置
ATE385736T1 (de) * 2005-07-01 2008-03-15 Ecole Polytech Polarimetrisch elektronisches abbildungssystem für eine kolposkopische vorrichtung
US20070191675A1 (en) * 2006-02-13 2007-08-16 Joel Gerardo Diaz Sanchez Actinic light colposcope and method to detect lesions in the lower female genital tract produced by human papilloma virus using an actinic light colposcope
WO2008115043A1 (fr) * 2007-03-22 2008-09-25 Diaz Sanchez Joel Gerardo Ensemble spéculum vaginal standard et système d'excitation de fluorescence variable à large spectre pour le diagnostic de maladies de l'appareil génital féminin
EP2174266A2 (fr) * 2007-08-03 2010-04-14 STI Medical Systems, LLC Analyse d'image informatisée pour une néoplasie intraépithéliale du col de l'utérus induite par acide acétique
US20120232408A1 (en) * 2009-11-30 2012-09-13 Laura Ann Weller-Brophy Method and Apparatus for Cervical Cancer Screening
JP5323130B2 (ja) 2011-05-26 2013-10-23 富士フイルム株式会社 蛍光分析装置および蛍光分析方法
CN103596487B (zh) 2011-07-15 2015-11-25 奥林巴斯株式会社 探头
US11446055B1 (en) 2018-10-18 2022-09-20 Lumoptik, Inc. Light assisted needle placement system and method
WO2022196493A1 (fr) * 2021-03-17 2022-09-22 テルモ株式会社 Programme, procédé de traitement d'informations, dispositif de diagnostic d'image et procédé de génération de modèle entraîné

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5421339A (en) * 1993-05-12 1995-06-06 Board Of Regents, The University Of Texas System Diagnosis of dysplasia using laser induced fluoroescence
US5456260A (en) * 1994-04-05 1995-10-10 The General Hospital Corporation Fluorescence detection of cell proliferation
US5450857A (en) * 1994-05-19 1995-09-19 Board Of Regents, The University Of Texas System Method for the diagnosis of cervical changes
ATE242999T1 (de) * 1994-07-14 2003-07-15 Washington Res Found Vorrichtung zum nachweis der barrett metaplasie in der speiseröhre
US5697373A (en) * 1995-03-14 1997-12-16 Board Of Regents, The University Of Texas System Optical method and apparatus for the diagnosis of cervical precancers using raman and fluorescence spectroscopies

Also Published As

Publication number Publication date
JP2008100064A (ja) 2008-05-01
JP2000515407A (ja) 2000-11-21
WO1998005253A1 (fr) 1998-02-12
EP0925015A1 (fr) 1999-06-30
CA2264870A1 (fr) 1998-02-12

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Effective date: 20130731