CA2264287C - A process for producing solid dosage forms - Google Patents

A process for producing solid dosage forms Download PDF

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Publication number
CA2264287C
CA2264287C CA002264287A CA2264287A CA2264287C CA 2264287 C CA2264287 C CA 2264287C CA 002264287 A CA002264287 A CA 002264287A CA 2264287 A CA2264287 A CA 2264287A CA 2264287 C CA2264287 C CA 2264287C
Authority
CA
Canada
Prior art keywords
acid
employed
dosage forms
graft copolymer
copolymers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002264287A
Other languages
English (en)
French (fr)
Other versions
CA2264287A1 (en
Inventor
Stephan Kothrade
Gunther Berndl
Dirk Simon
Axel Sanner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Publication of CA2264287A1 publication Critical patent/CA2264287A1/en
Application granted granted Critical
Publication of CA2264287C publication Critical patent/CA2264287C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F279/00—Macromolecular compounds obtained by polymerising monomers on to polymers of monomers having two or more carbon-to-carbon double bonds as defined in group C08F36/00
    • C08F279/02—Macromolecular compounds obtained by polymerising monomers on to polymers of monomers having two or more carbon-to-carbon double bonds as defined in group C08F36/00 on to polymers of conjugated dienes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L51/00—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C08L51/04—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers grafted on to rubbers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002264287A 1998-03-23 1999-03-22 A process for producing solid dosage forms Expired - Lifetime CA2264287C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19812688.3 1998-03-23
DE19812688A DE19812688A1 (de) 1998-03-23 1998-03-23 Verfahren zur Herstellung von festen Dosierungsformen

Publications (2)

Publication Number Publication Date
CA2264287A1 CA2264287A1 (en) 1999-09-23
CA2264287C true CA2264287C (en) 2008-10-07

Family

ID=7861972

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002264287A Expired - Lifetime CA2264287C (en) 1998-03-23 1999-03-22 A process for producing solid dosage forms

Country Status (6)

Country Link
US (2) US7022344B1 (enExample)
EP (1) EP0950404B1 (enExample)
JP (1) JP4813634B2 (enExample)
AT (1) ATE269060T1 (enExample)
CA (1) CA2264287C (enExample)
DE (2) DE19812688A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19814739A1 (de) * 1998-04-02 1999-10-07 Basf Ag Verwendung von Polyalkylenoxid-haltigen Pfropfpolymerisaten als Solubilisatoren
DE19847618A1 (de) * 1998-10-15 2000-04-20 Basf Ag Verfahren zur Herstellung von festen Dosierungsformen
CA2391707C (en) * 1999-07-30 2010-05-11 Smithkline Beecham Plc Multi-component pharmaceutical dosage form
DE10026698A1 (de) * 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
GB0102342D0 (en) 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
AU2004232370B2 (en) * 2003-04-21 2009-12-10 Euro-Celtique S.A. Tamper resistant dosage form comprising co-extruded, adverse agent particles and process of making same
TW200526274A (en) 2003-07-21 2005-08-16 Smithkline Beecham Plc Pharmaceutical formulations
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
CA2548834C (en) * 2003-12-09 2009-08-11 Euro-Celtique S.A. Tamper resistant co-extruded dosage form containing an active agent and an adverse agent and process of making same
JP4907514B2 (ja) * 2005-01-28 2012-03-28 株式会社リバース・プロテオミクス研究所 効率的にターゲット分子を探索する方法
WO2006125450A1 (en) * 2005-05-26 2006-11-30 Atef Mohammed Mostafa Darwish Rectal and vaginal suppositories containing misoprostol
EP1920767A1 (en) * 2006-11-09 2008-05-14 Abbott GmbH & Co. KG Melt-processed imatinib dosage form
EP2219624A2 (en) 2007-11-08 2010-08-25 Glaxo Group Limited Pharmaceutical formulations
DE102008059206A1 (de) * 2008-11-27 2010-06-10 Bayer Schering Pharma Aktiengesellschaft Pharmazeutische Darreichungsform enthaltend Nifedipin oder Nisoldipin und einen Angiotensin-II Antagonisten und/oder ein Diuretikum
RU2013118252A (ru) 2010-09-22 2014-10-27 МакНЕЙЛ-ППС, ИНК. Производство таблеток из порошковой смеси, обработанной излучением
US9511028B2 (en) 2012-05-01 2016-12-06 Johnson & Johnson Consumer Inc. Orally disintegrating tablet

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1043039A (en) * 1973-01-29 1978-11-21 Robert D. Lundberg Multiphase block and graft copolymers comprising a hydrophilic continuous phase and hydrophobic domains
FR2433949A1 (fr) * 1978-08-25 1980-03-21 Commissariat Energie Atomique Substrat hydrophobe apte a liberer une substance chimique
ATE37983T1 (de) * 1982-04-22 1988-11-15 Ici Plc Mittel mit verzoegerter freigabe.
DE3612212A1 (de) 1986-04-11 1987-10-15 Basf Ag Verfahren zur herstellung von festen pharmazeutischen formen
DE3612211A1 (de) 1986-04-11 1987-10-15 Basf Ag Kontinuierliches verfahren zum tablettieren
DE3812567A1 (de) 1988-04-15 1989-10-26 Basf Ag Verfahren zur herstellung pharmazeutischer mischungen
DE3830353A1 (de) 1988-09-07 1990-03-15 Basf Ag Verfahren zur kontinuierlichen herstellung von festen pharmazeutischen formen
DE4138513A1 (de) * 1991-11-23 1993-05-27 Basf Ag Feste pharmazeutische retardform
FR2699406B1 (fr) * 1992-12-21 1995-03-10 Commissariat Energie Atomique Films à base de copolymères, leurs applications dans des systèmes transdermiques et leurs procédés de préparation.
KR970701739A (ko) 1994-03-04 1997-04-12 브라운 데이비드 피. 블록 공중합체와 그라프트 공중합체 및 이들과 연관된 방법(Block and graft copolymers and methods relating thereto)

Also Published As

Publication number Publication date
ATE269060T1 (de) 2004-07-15
DE19812688A1 (de) 1999-09-30
JP4813634B2 (ja) 2011-11-09
US20050129757A1 (en) 2005-06-16
DE59909717D1 (de) 2004-07-22
EP0950404A3 (de) 1999-12-29
US7022344B1 (en) 2006-04-04
JPH11322585A (ja) 1999-11-24
CA2264287A1 (en) 1999-09-23
US7419685B2 (en) 2008-09-02
EP0950404B1 (de) 2004-06-16
EP0950404A2 (de) 1999-10-20

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Effective date: 20190322