CA2263904A1 - Process to obtain oestrogens from mare's urine - Google Patents
Process to obtain oestrogens from mare's urineInfo
- Publication number
- CA2263904A1 CA2263904A1 CA002263904A CA2263904A CA2263904A1 CA 2263904 A1 CA2263904 A1 CA 2263904A1 CA 002263904 A CA002263904 A CA 002263904A CA 2263904 A CA2263904 A CA 2263904A CA 2263904 A1 CA2263904 A1 CA 2263904A1
- Authority
- CA
- Canada
- Prior art keywords
- urine
- oestrogens
- mare
- mares
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000262 estrogen Substances 0.000 title abstract 3
- 210000002700 urine Anatomy 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 1
- 238000002414 normal-phase solid-phase extraction Methods 0.000 abstract 1
- 239000000741 silica gel Substances 0.000 abstract 1
- 229910002027 silica gel Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/22—Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Extraction Or Liquid Replacement (AREA)
- Saccharide Compounds (AREA)
- Vehicle Interior And Exterior Ornaments, Soundproofing, And Insulation (AREA)
- Organic Insulating Materials (AREA)
Abstract
A method for obtaining an extract containing the natural mixture of conjugated oestrogens from mares urine by solid-phase extraction of the mixture of conjugated oestrogens from the urine of pregnant mares on RP silica gel is described.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP1996/003819 WO1998008525A1 (en) | 1996-08-30 | 1996-08-30 | Process to obtain oestrogens from mare's urine |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2263904A1 true CA2263904A1 (en) | 1998-03-05 |
CA2263904C CA2263904C (en) | 2007-08-07 |
Family
ID=8166299
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002263904A Expired - Fee Related CA2263904C (en) | 1996-08-30 | 1996-08-30 | Process to obtain oestrogens from mare's urine |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0927040B1 (en) |
JP (1) | JP4125788B2 (en) |
AT (1) | ATE264110T1 (en) |
AU (1) | AU722084B2 (en) |
CA (1) | CA2263904C (en) |
CZ (1) | CZ298762B6 (en) |
DE (3) | DE19681616B4 (en) |
DK (1) | DK0927040T3 (en) |
ES (1) | ES2219697T3 (en) |
HK (1) | HK1023063A1 (en) |
HU (1) | HU228765B1 (en) |
IL (1) | IL128671A (en) |
NO (1) | NO318378B1 (en) |
PL (1) | PL185920B1 (en) |
PT (1) | PT927040E (en) |
SK (1) | SK281367B6 (en) |
WO (1) | WO1998008525A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8268351B2 (en) | 2001-12-14 | 2012-09-18 | Abbott Products Gmbh | Matrix film tablet with controlled release of a natural mixture of conjugated estrogens |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10037389A1 (en) * | 2000-08-01 | 2002-02-14 | Solvay Pharm Gmbh | Method and device for the enrichment and stabilization of conjugated estrogens from mare's urine |
DE10159161A1 (en) | 2001-12-01 | 2003-06-18 | Solvay Pharm Gmbh | Process for obtaining estrogens from mare's urine |
TWI332400B (en) | 2001-12-14 | 2010-11-01 | Solvay Pharm Gmbh | Preformulation for the tableting of natural mixtures of conjugated estrogens |
AR041121A1 (en) * | 2002-10-11 | 2005-05-04 | Solvay Pharm Gmbh | PROCEDURE FOR OBTAINING A NATURAL MIXTURE OF CONJUGATED STROGENS |
US20040072814A1 (en) | 2002-10-11 | 2004-04-15 | Solvay Pharmaceuticals Gmbh | Method for obtaining a natural mixture of conjugated equine estrogens depleted in non-conjugated lipophilic compounds |
CN1332973C (en) * | 2003-03-06 | 2007-08-22 | 深圳市海达克实业有限公司 | Extraction process of conjugated female hormone |
CN100422206C (en) * | 2003-07-17 | 2008-10-01 | 索尔瓦药物有限公司 | Method for obtaining a natural mixture of conjugated equine estrogens |
-
1996
- 1996-08-30 DE DE19681616A patent/DE19681616B4/en not_active Expired - Fee Related
- 1996-08-30 HU HU9903670A patent/HU228765B1/en not_active IP Right Cessation
- 1996-08-30 PL PL96331885A patent/PL185920B1/en unknown
- 1996-08-30 WO PCT/EP1996/003819 patent/WO1998008525A1/en active IP Right Grant
- 1996-08-30 DK DK96930986T patent/DK0927040T3/en active
- 1996-08-30 JP JP51119498A patent/JP4125788B2/en not_active Expired - Fee Related
- 1996-08-30 IL IL12867196A patent/IL128671A/en not_active IP Right Cessation
- 1996-08-30 ES ES96930986T patent/ES2219697T3/en not_active Expired - Lifetime
- 1996-08-30 PT PT96930986T patent/PT927040E/en unknown
- 1996-08-30 DE DE59610986T patent/DE59610986D1/en not_active Expired - Lifetime
- 1996-08-30 AT AT96930986T patent/ATE264110T1/en active
- 1996-08-30 SK SK244-99A patent/SK281367B6/en not_active IP Right Cessation
- 1996-08-30 EP EP96930986A patent/EP0927040B1/en not_active Expired - Lifetime
- 1996-08-30 DE DE19681616D patent/DE19681616D2/en not_active Expired - Lifetime
- 1996-08-30 AU AU69856/96A patent/AU722084B2/en not_active Ceased
- 1996-08-30 CZ CZ0059999A patent/CZ298762B6/en not_active IP Right Cessation
- 1996-08-30 CA CA002263904A patent/CA2263904C/en not_active Expired - Fee Related
-
1999
- 1999-02-26 NO NO19990953A patent/NO318378B1/en not_active IP Right Cessation
-
2000
- 2000-04-06 HK HK00102091A patent/HK1023063A1/en not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8268351B2 (en) | 2001-12-14 | 2012-09-18 | Abbott Products Gmbh | Matrix film tablet with controlled release of a natural mixture of conjugated estrogens |
Also Published As
Publication number | Publication date |
---|---|
DE19681616D2 (en) | 1999-09-30 |
EP0927040A1 (en) | 1999-07-07 |
SK281367B6 (en) | 2001-02-12 |
HK1023063A1 (en) | 2000-09-01 |
ATE264110T1 (en) | 2004-04-15 |
PL331885A1 (en) | 1999-08-16 |
WO1998008525A1 (en) | 1998-03-05 |
AU722084B2 (en) | 2000-07-20 |
CA2263904C (en) | 2007-08-07 |
ES2219697T3 (en) | 2004-12-01 |
NO990953L (en) | 1999-02-26 |
SK24499A3 (en) | 1999-10-08 |
AU6985696A (en) | 1998-03-19 |
NO318378B1 (en) | 2005-03-14 |
DK0927040T3 (en) | 2004-05-10 |
DE19681616B4 (en) | 2006-03-09 |
HUP9903670A2 (en) | 2000-03-28 |
CZ59999A3 (en) | 1999-06-16 |
PT927040E (en) | 2004-08-31 |
EP0927040B1 (en) | 2004-04-14 |
PL185920B1 (en) | 2003-08-29 |
IL128671A (en) | 2001-03-19 |
IL128671A0 (en) | 2000-01-31 |
JP4125788B2 (en) | 2008-07-30 |
HU228765B1 (en) | 2013-05-28 |
JP2000517309A (en) | 2000-12-26 |
DE59610986D1 (en) | 2004-05-19 |
HUP9903670A3 (en) | 2000-05-29 |
NO990953D0 (en) | 1999-02-26 |
CZ298762B6 (en) | 2008-01-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20160830 |