CA2263904A1 - Process to obtain oestrogens from mare's urine - Google Patents

Process to obtain oestrogens from mare's urine

Info

Publication number
CA2263904A1
CA2263904A1 CA002263904A CA2263904A CA2263904A1 CA 2263904 A1 CA2263904 A1 CA 2263904A1 CA 002263904 A CA002263904 A CA 002263904A CA 2263904 A CA2263904 A CA 2263904A CA 2263904 A1 CA2263904 A1 CA 2263904A1
Authority
CA
Canada
Prior art keywords
urine
oestrogens
mare
mares
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002263904A
Other languages
French (fr)
Other versions
CA2263904C (en
Inventor
Ivan Ban
Friedrich Borchers
Henning Heinemann
Heinz-Helmer Rasche
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Products GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2263904A1 publication Critical patent/CA2263904A1/en
Application granted granted Critical
Publication of CA2263904C publication Critical patent/CA2263904C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/22Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Saccharide Compounds (AREA)
  • Vehicle Interior And Exterior Ornaments, Soundproofing, And Insulation (AREA)
  • Organic Insulating Materials (AREA)

Abstract

A method for obtaining an extract containing the natural mixture of conjugated oestrogens from mares urine by solid-phase extraction of the mixture of conjugated oestrogens from the urine of pregnant mares on RP silica gel is described.
CA002263904A 1996-08-30 1996-08-30 Process to obtain oestrogens from mare's urine Expired - Fee Related CA2263904C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP1996/003819 WO1998008525A1 (en) 1996-08-30 1996-08-30 Process to obtain oestrogens from mare's urine

Publications (2)

Publication Number Publication Date
CA2263904A1 true CA2263904A1 (en) 1998-03-05
CA2263904C CA2263904C (en) 2007-08-07

Family

ID=8166299

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002263904A Expired - Fee Related CA2263904C (en) 1996-08-30 1996-08-30 Process to obtain oestrogens from mare's urine

Country Status (17)

Country Link
EP (1) EP0927040B1 (en)
JP (1) JP4125788B2 (en)
AT (1) ATE264110T1 (en)
AU (1) AU722084B2 (en)
CA (1) CA2263904C (en)
CZ (1) CZ298762B6 (en)
DE (3) DE19681616B4 (en)
DK (1) DK0927040T3 (en)
ES (1) ES2219697T3 (en)
HK (1) HK1023063A1 (en)
HU (1) HU228765B1 (en)
IL (1) IL128671A (en)
NO (1) NO318378B1 (en)
PL (1) PL185920B1 (en)
PT (1) PT927040E (en)
SK (1) SK281367B6 (en)
WO (1) WO1998008525A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8268351B2 (en) 2001-12-14 2012-09-18 Abbott Products Gmbh Matrix film tablet with controlled release of a natural mixture of conjugated estrogens

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10037389A1 (en) * 2000-08-01 2002-02-14 Solvay Pharm Gmbh Method and device for the enrichment and stabilization of conjugated estrogens from mare's urine
DE10159161A1 (en) 2001-12-01 2003-06-18 Solvay Pharm Gmbh Process for obtaining estrogens from mare's urine
TWI332400B (en) 2001-12-14 2010-11-01 Solvay Pharm Gmbh Preformulation for the tableting of natural mixtures of conjugated estrogens
AR041121A1 (en) * 2002-10-11 2005-05-04 Solvay Pharm Gmbh PROCEDURE FOR OBTAINING A NATURAL MIXTURE OF CONJUGATED STROGENS
US20040072814A1 (en) 2002-10-11 2004-04-15 Solvay Pharmaceuticals Gmbh Method for obtaining a natural mixture of conjugated equine estrogens depleted in non-conjugated lipophilic compounds
CN1332973C (en) * 2003-03-06 2007-08-22 深圳市海达克实业有限公司 Extraction process of conjugated female hormone
CN100422206C (en) * 2003-07-17 2008-10-01 索尔瓦药物有限公司 Method for obtaining a natural mixture of conjugated equine estrogens

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8268351B2 (en) 2001-12-14 2012-09-18 Abbott Products Gmbh Matrix film tablet with controlled release of a natural mixture of conjugated estrogens

Also Published As

Publication number Publication date
DE19681616D2 (en) 1999-09-30
EP0927040A1 (en) 1999-07-07
SK281367B6 (en) 2001-02-12
HK1023063A1 (en) 2000-09-01
ATE264110T1 (en) 2004-04-15
PL331885A1 (en) 1999-08-16
WO1998008525A1 (en) 1998-03-05
AU722084B2 (en) 2000-07-20
CA2263904C (en) 2007-08-07
ES2219697T3 (en) 2004-12-01
NO990953L (en) 1999-02-26
SK24499A3 (en) 1999-10-08
AU6985696A (en) 1998-03-19
NO318378B1 (en) 2005-03-14
DK0927040T3 (en) 2004-05-10
DE19681616B4 (en) 2006-03-09
HUP9903670A2 (en) 2000-03-28
CZ59999A3 (en) 1999-06-16
PT927040E (en) 2004-08-31
EP0927040B1 (en) 2004-04-14
PL185920B1 (en) 2003-08-29
IL128671A (en) 2001-03-19
IL128671A0 (en) 2000-01-31
JP4125788B2 (en) 2008-07-30
HU228765B1 (en) 2013-05-28
JP2000517309A (en) 2000-12-26
DE59610986D1 (en) 2004-05-19
HUP9903670A3 (en) 2000-05-29
NO990953D0 (en) 1999-02-26
CZ298762B6 (en) 2008-01-23

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20160830