CA2261291A1 - Pasteurisation de solutions d'immunoglobulines - Google Patents

Pasteurisation de solutions d'immunoglobulines Download PDF

Info

Publication number
CA2261291A1
CA2261291A1 CA002261291A CA2261291A CA2261291A1 CA 2261291 A1 CA2261291 A1 CA 2261291A1 CA 002261291 A CA002261291 A CA 002261291A CA 2261291 A CA2261291 A CA 2261291A CA 2261291 A1 CA2261291 A1 CA 2261291A1
Authority
CA
Canada
Prior art keywords
immunoglobulin
pasteurization
solution
pasteurized
aggregate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002261291A
Other languages
English (en)
Inventor
Joseph Bertolini
Germano Coppola
Jeffrey Raymond Davies
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CSL Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AUPO1112A external-priority patent/AUPO111296A0/en
Priority claimed from AUPO5462A external-priority patent/AUPO546297A0/en
Application filed by Individual filed Critical Individual
Publication of CA2261291A1 publication Critical patent/CA2261291A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/04—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0023—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Abstract

Cette invention concerne un procédé de pasteurisation d'une solution d'immunoglobulines, et notamment une solution de gammaglobulines, qui consiste à chauffer la solution à une température comprise entre 50 ·C et 70 ·C pendant un laps de temps compris entre 1 et 20 heures, à un pH compris entre 4,0 et 6,0, et en présence de 20 à 40 % en poids de sorbitol ou de 25 à 45 % en poids de saccharose, la concentration en protéines de la solution étant approximativement inférieure ou égale à 3 % en poids.
CA002261291A 1996-07-18 1997-07-18 Pasteurisation de solutions d'immunoglobulines Abandoned CA2261291A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AUPO1112 1996-07-18
AUPO1112A AUPO111296A0 (en) 1996-07-18 1996-07-18 Pasteurization of immunoglobulin solutions
AUPO5462 1997-03-05
AUPO5462A AUPO546297A0 (en) 1997-03-05 1997-03-05 Pasteurization of immunoglobulin solutions

Publications (1)

Publication Number Publication Date
CA2261291A1 true CA2261291A1 (fr) 1998-01-29

Family

ID=25645219

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002261291A Abandoned CA2261291A1 (fr) 1996-07-18 1997-07-18 Pasteurisation de solutions d'immunoglobulines

Country Status (5)

Country Link
EP (1) EP0954534A1 (fr)
JP (1) JP2000515857A (fr)
KR (1) KR20000067911A (fr)
CA (1) CA2261291A1 (fr)
WO (1) WO1998003550A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005320248A (ja) * 2002-04-22 2005-11-17 Mitsubishi Pharma Corp 免疫グロブリン製剤の製造方法
US7403561B2 (en) * 2003-04-04 2008-07-22 Avid Technology, Inc. Fixed bit rate, intraframe compression and decompression of video
CA2610839C (fr) 2005-06-14 2019-06-25 Amgen Inc. Preparations de proteines a tamponnage spontane
EP2249661B1 (fr) 2008-01-22 2018-05-16 Multimerics APS Produits et méthodes pour prévenir une infection
KR102413592B1 (ko) 2016-10-21 2022-06-27 암젠 인크 약학적 제형 및 그의 제조 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3176491D1 (en) * 1980-03-05 1987-11-26 Miles Lab Pasteurized therapeutically active protein compositions
CA1310267C (fr) * 1986-07-09 1992-11-17 Yutaka Hirao Procede pour le thermotraitement de _-globuline non modifiee
GB8628104D0 (en) * 1986-11-25 1986-12-31 Connaught Lab Pasteurization of immunoglobin solutions
JP3220539B2 (ja) * 1992-12-25 2001-10-22 日本ケミカルリサーチ株式会社 活性乳蛋白成分含有製品およびその製造法

Also Published As

Publication number Publication date
KR20000067911A (ko) 2000-11-25
JP2000515857A (ja) 2000-11-28
WO1998003550A1 (fr) 1998-01-29
EP0954534A1 (fr) 1999-11-10

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Legal Events

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FZDE Dead