CA2261291A1 - Pasteurisation de solutions d'immunoglobulines - Google Patents
Pasteurisation de solutions d'immunoglobulines Download PDFInfo
- Publication number
- CA2261291A1 CA2261291A1 CA002261291A CA2261291A CA2261291A1 CA 2261291 A1 CA2261291 A1 CA 2261291A1 CA 002261291 A CA002261291 A CA 002261291A CA 2261291 A CA2261291 A CA 2261291A CA 2261291 A1 CA2261291 A1 CA 2261291A1
- Authority
- CA
- Canada
- Prior art keywords
- immunoglobulin
- pasteurization
- solution
- pasteurized
- aggregate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/04—Heat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0023—Heat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
Cette invention concerne un procédé de pasteurisation d'une solution d'immunoglobulines, et notamment une solution de gammaglobulines, qui consiste à chauffer la solution à une température comprise entre 50 ·C et 70 ·C pendant un laps de temps compris entre 1 et 20 heures, à un pH compris entre 4,0 et 6,0, et en présence de 20 à 40 % en poids de sorbitol ou de 25 à 45 % en poids de saccharose, la concentration en protéines de la solution étant approximativement inférieure ou égale à 3 % en poids.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPO1112A AUPO111296A0 (en) | 1996-07-18 | 1996-07-18 | Pasteurization of immunoglobulin solutions |
AUPO1112 | 1996-07-18 | ||
AUPO5462A AUPO546297A0 (en) | 1997-03-05 | 1997-03-05 | Pasteurization of immunoglobulin solutions |
AUPO5462 | 1997-03-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2261291A1 true CA2261291A1 (fr) | 1998-01-29 |
Family
ID=25645219
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002261291A Abandoned CA2261291A1 (fr) | 1996-07-18 | 1997-07-18 | Pasteurisation de solutions d'immunoglobulines |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0954534A1 (fr) |
JP (1) | JP2000515857A (fr) |
KR (1) | KR20000067911A (fr) |
CA (1) | CA2261291A1 (fr) |
WO (1) | WO1998003550A1 (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005320248A (ja) * | 2002-04-22 | 2005-11-17 | Mitsubishi Pharma Corp | 免疫グロブリン製剤の製造方法 |
US7403561B2 (en) * | 2003-04-04 | 2008-07-22 | Avid Technology, Inc. | Fixed bit rate, intraframe compression and decompression of video |
US20080311078A1 (en) | 2005-06-14 | 2008-12-18 | Gokarn Yatin R | Self-Buffering Protein Formulations |
EP2249661B1 (fr) * | 2008-01-22 | 2018-05-16 | Multimerics APS | Produits et méthodes pour prévenir une infection |
MX2019004580A (es) | 2016-10-21 | 2019-08-12 | Amgen Inc | Formulaciones farmaceuticas y metodos para prepararlas. |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0035204B2 (fr) * | 1980-03-05 | 1991-05-22 | Miles Inc. | Compositions pasteurisées de protéines thérapeutiquement actives |
CA1310267C (fr) * | 1986-07-09 | 1992-11-17 | Yutaka Hirao | Procede pour le thermotraitement de _-globuline non modifiee |
GB8628104D0 (en) * | 1986-11-25 | 1986-12-31 | Connaught Lab | Pasteurization of immunoglobin solutions |
JP3220539B2 (ja) * | 1992-12-25 | 2001-10-22 | 日本ケミカルリサーチ株式会社 | 活性乳蛋白成分含有製品およびその製造法 |
-
1997
- 1997-07-18 CA CA002261291A patent/CA2261291A1/fr not_active Abandoned
- 1997-07-18 JP JP10506378A patent/JP2000515857A/ja active Pending
- 1997-07-18 EP EP97930259A patent/EP0954534A1/fr not_active Withdrawn
- 1997-07-18 WO PCT/AU1997/000454 patent/WO1998003550A1/fr not_active Application Discontinuation
- 1997-07-18 KR KR1019997000368A patent/KR20000067911A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JP2000515857A (ja) | 2000-11-28 |
WO1998003550A1 (fr) | 1998-01-29 |
KR20000067911A (ko) | 2000-11-25 |
EP0954534A1 (fr) | 1999-11-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |