CA2257180A1 - Method of identifying cytochrome p450 - Google Patents

Method of identifying cytochrome p450 Download PDF

Info

Publication number
CA2257180A1
CA2257180A1 CA002257180A CA2257180A CA2257180A1 CA 2257180 A1 CA2257180 A1 CA 2257180A1 CA 002257180 A CA002257180 A CA 002257180A CA 2257180 A CA2257180 A CA 2257180A CA 2257180 A1 CA2257180 A1 CA 2257180A1
Authority
CA
Canada
Prior art keywords
leu
cytochrome
asp
gly
arg
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002257180A
Other languages
English (en)
French (fr)
Inventor
P. Martin Petkovich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Queens University at Kingston
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/724,466 external-priority patent/US6063606A/en
Application filed by Individual filed Critical Individual
Publication of CA2257180A1 publication Critical patent/CA2257180A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0077—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002257180A 1996-06-21 1997-06-23 Method of identifying cytochrome p450 Abandoned CA2257180A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US66754696A 1996-06-21 1996-06-21
US08/667,546 1996-06-21
US08/724,466 US6063606A (en) 1996-06-21 1996-10-01 Retinoid metabolizing protein
US08/724,466 1996-10-01

Publications (1)

Publication Number Publication Date
CA2257180A1 true CA2257180A1 (en) 1997-12-31

Family

ID=27099706

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2257352A Expired - Fee Related CA2257352C (en) 1996-06-21 1997-06-23 Retinoid metabolizing protein
CA002257180A Abandoned CA2257180A1 (en) 1996-06-21 1997-06-23 Method of identifying cytochrome p450

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA2257352A Expired - Fee Related CA2257352C (en) 1996-06-21 1997-06-23 Retinoid metabolizing protein

Country Status (9)

Country Link
US (1) US6306624B1 (https=)
EP (2) EP0935676A2 (https=)
JP (2) JP4283342B2 (https=)
AT (1) ATE309370T1 (https=)
AU (2) AU3332197A (https=)
CA (2) CA2257352C (https=)
DE (1) DE69734586T2 (https=)
IN (1) IN186424B (https=)
WO (2) WO1997049815A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE50014590D1 (de) * 1999-07-27 2007-10-04 Basf Ag Modifizierte cytochrom p450-monooxygenasen
WO2001019161A2 (en) * 1999-09-17 2001-03-22 Isis Pharmaceuticals, Inc. ANTISENSE MODULATION OF TRANSFORMING GROWTH FACTOR-β EXPRESSION
US7115558B2 (en) 1999-12-16 2006-10-03 Cytochroma Inc. P450RAI-2(P450 Cytochrome 26B), encoding nucleic acid molecules and methods and uses thereof
CA2396511A1 (en) 1999-12-16 2001-06-21 Cytochroma Inc. Cytochrome p450rai-2 and related proteins
AU2002215776A1 (en) * 2000-12-15 2002-06-24 Cytochroma Inc. P450rai-2 (p450 cytochrome 26b), encoding nucleic acid molecules and methods and uses thereof
US6444222B1 (en) * 2001-05-08 2002-09-03 Verigen Transplantation Services International Ag Reinforced matrices
JP2005512511A (ja) 2001-05-23 2005-05-12 サイトクロマ インコーポレーティッド レチノイン酸代謝性シトクロムｐ４５０
JP2005512532A (ja) * 2001-08-03 2005-05-12 ディヴァーサ コーポレイション Ｐ４５０酵素、それらをコードした核酸及びそれらの作製と使用
US7288407B2 (en) 2002-05-02 2007-10-30 Cytochroma, Inc. Stable cytochrome P450 24 (CYP24) expressing cell line and methods and uses thereof
US7427670B2 (en) 2003-12-19 2008-09-23 Cytochroma Inc. Cytochrome P450 24 (CYP24) monoclonal antibody and methods and uses thereof
WO2011088148A1 (en) * 2010-01-12 2011-07-21 Isis Pharmaceuticals, Inc. Modulation of transforming growth factor-beta 1 expression

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5429948A (en) * 1988-03-02 1995-07-04 Gentest Corporation Human cell line stably expressing 5cDNAS encoding procarcinogen-activating enzymes and related mutagenicity assays
CA2100582A1 (en) * 1991-03-18 1992-09-19 David J. Mangelsdorf Response element compositions and assays employing same
WO1993022331A1 (en) * 1992-04-28 1993-11-11 The Regents Of The University Of Michigan Human crabp-i and crabp-ii
EP0721984A1 (en) * 1995-01-13 1996-07-17 Leuven Research & Development V.Z.W. Enhancer element of gene expression
US5650279A (en) * 1995-01-27 1997-07-22 Allergan, Inc. Gene sequence induced in skin by retinoids

Also Published As

Publication number Publication date
DE69734586T2 (de) 2006-08-10
JP2000513928A (ja) 2000-10-24
AU3332197A (en) 1998-01-14
ATE309370T1 (de) 2005-11-15
DE69734586D1 (de) 2005-12-15
WO1997049832A2 (en) 1997-12-31
EP0910644B1 (en) 2005-11-09
CA2257352A1 (en) 1997-12-31
WO1997049832A3 (en) 1998-03-26
US6306624B1 (en) 2001-10-23
EP0910644A1 (en) 1999-04-28
JP2000513927A (ja) 2000-10-24
CA2257352C (en) 2011-11-29
JP4283342B2 (ja) 2009-06-24
IN186424B (https=) 2001-09-01
AU3162097A (en) 1998-01-14
EP0935676A2 (en) 1999-08-18
WO1997049815A1 (en) 1997-12-31

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Legal Events

Date Code Title Description
FZDE Discontinued