CA2255952A1 - Nucleic acid sensor - Google Patents

Nucleic acid sensor Download PDF

Info

Publication number
CA2255952A1
CA2255952A1 CA002255952A CA2255952A CA2255952A1 CA 2255952 A1 CA2255952 A1 CA 2255952A1 CA 002255952 A CA002255952 A CA 002255952A CA 2255952 A CA2255952 A CA 2255952A CA 2255952 A1 CA2255952 A1 CA 2255952A1
Authority
CA
Canada
Prior art keywords
membrane
nucleic acid
spanning
biosensor
proximal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002255952A
Other languages
English (en)
French (fr)
Inventor
Margaret Harding
Sally Wright Lucas
Vijoleta Lucija Bronislava Braach-Maksvytis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ambri Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2255952A1 publication Critical patent/CA2255952A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA002255952A 1996-05-22 1997-05-22 Nucleic acid sensor Abandoned CA2255952A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1812596P 1996-05-22 1996-05-22
US60/018,125 1996-05-22
PCT/AU1997/000316 WO1997044651A1 (en) 1996-05-22 1997-05-22 Nucleic acid sensor

Publications (1)

Publication Number Publication Date
CA2255952A1 true CA2255952A1 (en) 1997-11-27

Family

ID=21786371

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002255952A Abandoned CA2255952A1 (en) 1996-05-22 1997-05-22 Nucleic acid sensor

Country Status (5)

Country Link
EP (1) EP0990149A4 (de)
JP (1) JP2000513811A (de)
AU (1) AU734086B2 (de)
CA (1) CA2255952A1 (de)
WO (1) WO1997044651A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6071699A (en) 1996-06-07 2000-06-06 California Institute Of Technology Nucleic acid mediated electron transfer
US5591578A (en) * 1993-12-10 1997-01-07 California Institute Of Technology Nucleic acid mediated electron transfer
US5824473A (en) 1993-12-10 1998-10-20 California Institute Of Technology Nucleic acid mediated electron transfer
US5952172A (en) 1993-12-10 1999-09-14 California Institute Of Technology Nucleic acid mediated electron transfer
AUPN366895A0 (en) * 1995-06-20 1995-07-13 Australian Membrane And Biotechnology Research Institute Detection of small analytes
US6127127A (en) * 1995-06-27 2000-10-03 The University Of North Carolina At Chapel Hill Monolayer and electrode for detecting a label-bearing target and method of use thereof
US6387625B1 (en) 1995-06-27 2002-05-14 The University Of North Carolina At Chapel Hill Monolayer and electrode for detecting a label-bearing target and method of use thereof
US6444423B1 (en) 1996-06-07 2002-09-03 Molecular Dynamics, Inc. Nucleosides comprising polydentate ligands
US6096273A (en) 1996-11-05 2000-08-01 Clinical Micro Sensors Electrodes linked via conductive oligomers to nucleic acids
US7014992B1 (en) * 1996-11-05 2006-03-21 Clinical Micro Sensors, Inc. Conductive oligomers attached to electrodes and nucleoside analogs
US7160678B1 (en) 1996-11-05 2007-01-09 Clinical Micro Sensors, Inc. Compositions for the electronic detection of analytes utilizing monolayers
US7381525B1 (en) 1997-03-07 2008-06-03 Clinical Micro Sensors, Inc. AC/DC voltage apparatus for detection of nucleic acids
US7045285B1 (en) 1996-11-05 2006-05-16 Clinical Micro Sensors, Inc. Electronic transfer moieties attached to peptide nucleic acids
US7393645B2 (en) 1996-11-05 2008-07-01 Clinical Micro Sensors, Inc. Compositions for the electronic detection of analytes utilizing monolayers
US6503452B1 (en) * 1996-11-29 2003-01-07 The Board Of Trustees Of The Leland Stanford Junior University Biosensor arrays and methods
US6306584B1 (en) * 1997-01-21 2001-10-23 President And Fellows Of Harvard College Electronic-property probing of biological molecules at surfaces
US6013459A (en) 1997-06-12 2000-01-11 Clinical Micro Sensors, Inc. Detection of analytes using reorganization energy
AU744503B2 (en) 1997-06-12 2002-02-28 Clinical Micro Sensors, Inc. Electronic methods for the detection of analytes
IL121312A (en) 1997-07-14 2001-09-13 Technion Res & Dev Foundation Microelectronic components, their manufacture and electronic networks containing them
US6686150B1 (en) 1998-01-27 2004-02-03 Clinical Micro Sensors, Inc. Amplification of nucleic acids with electronic detection
US6761816B1 (en) 1998-06-23 2004-07-13 Clinical Micro Systems, Inc. Printed circuit boards with monolayers and capture ligands
US6740518B1 (en) 1998-09-17 2004-05-25 Clinical Micro Sensors, Inc. Signal detection techniques for the detection of analytes
US6541617B1 (en) 1998-10-27 2003-04-01 Clinical Micro Sensors, Inc. Detection of target analytes using particles and electrodes
IL126776A (en) 1998-10-27 2001-04-30 Technion Res & Dev Foundation A method of investing gold
US6833267B1 (en) 1998-12-30 2004-12-21 Clinical Micro Sensors, Inc. Tissue collection devices containing biosensors
US6942771B1 (en) 1999-04-21 2005-09-13 Clinical Micro Sensors, Inc. Microfluidic systems in the electrochemical detection of target analytes
US7364920B2 (en) 1999-10-27 2008-04-29 Technion Research And Development Foundation Ltd. Method for gold deposition
DE10015547C2 (de) * 2000-03-30 2002-02-14 Aventis Res & Tech Gmbh & Co Verfahren zur Detektion von Molekülen mittels Impedanzspektroskopie und Vorrichtung zur Durchführung dieser Verfahren
JP2003533211A (ja) * 2000-05-18 2003-11-11 ザ・ボード・オブ・トラスティーズ・オブ・ザ・レランド・スタンフォード・ジュニア・ユニバーシティ 脂質二重層アレイ方法およびデバイス
US7138121B2 (en) 2003-01-23 2006-11-21 Spangler Brenda D Biosensors utilizing dendrimer-immobilized ligands and there use thereof
US7824927B2 (en) * 2005-04-05 2010-11-02 George Mason Intellectual Properties, Inc. Analyte detection using an active assay
US8906609B1 (en) 2005-09-26 2014-12-09 Arrowhead Center, Inc. Label-free biomolecule sensor based on surface charge modulated ionic conductance
US20180299400A1 (en) * 2015-10-21 2018-10-18 Genia Technologies, Inc. Use of fluoropolymers as a hydrophobic layer to support lipid bilayer formation for nanopore based dna sequencing
CN113070113B (zh) * 2021-06-03 2021-08-20 成都齐碳科技有限公司 芯片结构、成膜方法、纳米孔测序装置及应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69030811T2 (de) * 1989-01-27 1997-10-02 Au Membrane & Biotech Res Inst Rezeptormembranen und selektive steuerung des ionenflusses durch ionophoren
US5328847A (en) * 1990-02-20 1994-07-12 Case George D Thin membrane sensor with biochemical switch
EP0639269B1 (de) * 1991-03-27 2002-06-12 Ambri Limited Ionisches reservoir an der oberfläche einer elektrode
US6573109B1 (en) * 1993-04-21 2003-06-03 Australian Membrane And Biotechnology Research Institute Surface amplifier
AUPM950094A0 (en) * 1994-11-16 1994-12-08 Australian Membrane And Biotechnology Research Institute Detection device and method
AUPN366995A0 (en) * 1995-06-20 1995-07-13 Australian Membrane And Biotechnology Research Institute Self-assembly of bilayer membrane sensors

Also Published As

Publication number Publication date
EP0990149A1 (de) 2000-04-05
AU2757897A (en) 1997-12-09
WO1997044651A1 (en) 1997-11-27
AU734086B2 (en) 2001-05-31
EP0990149A4 (de) 2003-02-26
JP2000513811A (ja) 2000-10-17

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