CA2252706A1 - Polypeptide conjugates for transporting substances across cell membranes - Google Patents
Polypeptide conjugates for transporting substances across cell membranes Download PDFInfo
- Publication number
- CA2252706A1 CA2252706A1 CA002252706A CA2252706A CA2252706A1 CA 2252706 A1 CA2252706 A1 CA 2252706A1 CA 002252706 A CA002252706 A CA 002252706A CA 2252706 A CA2252706 A CA 2252706A CA 2252706 A1 CA2252706 A1 CA 2252706A1
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- polypeptide
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
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- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1634796P | 1996-05-01 | 1996-05-01 | |
| US60/016,347 | 1996-05-01 | ||
| US2860996P | 1996-10-23 | 1996-10-23 | |
| US60/028,609 | 1996-10-23 | ||
| PCT/US1997/007335 WO1997040854A2 (en) | 1996-05-01 | 1997-04-30 | Polypeptide conjugates for transporting substances across cell membranes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2252706A1 true CA2252706A1 (en) | 1997-11-06 |
Family
ID=26688485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002252706A Abandoned CA2252706A1 (en) | 1996-05-01 | 1997-04-30 | Polypeptide conjugates for transporting substances across cell membranes |
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| EP (1) | EP0966303A2 (enrdf_load_html_response) |
| JP (1) | JP2000509394A (enrdf_load_html_response) |
| AU (1) | AU729643B2 (enrdf_load_html_response) |
| CA (1) | CA2252706A1 (enrdf_load_html_response) |
| WO (1) | WO1997040854A2 (enrdf_load_html_response) |
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| US6730293B1 (en) | 1999-08-24 | 2004-05-04 | Cellgate, Inc. | Compositions and methods for treating inflammatory diseases of the skin |
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| JP2004523480A (ja) * | 2000-08-22 | 2004-08-05 | ニュー リバー ファーマシューティカルズ， インコーポレイテッド | 活性作用物質送達系ならびに活性作用物質の保護および投与方法 |
| CA2428971A1 (en) * | 2000-11-14 | 2003-05-01 | New River Pharmaceuticals Inc. | Conjugates of a therapeutic agent and a peptide carrier |
| EP2316468A1 (en) * | 2002-02-22 | 2011-05-04 | Shire LLC | Delivery system and methods for protecting and administering dextroamphetamine |
| MXPA05007322A (es) | 2003-01-06 | 2006-02-17 | Angiochem Inc | Aprotinina y analogos como portadores a traves de la barrera sangre-cerebro. |
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| RU2007136616A (ru) | 2005-03-03 | 2009-04-10 | Риванс Терапьютикс, Инк. (Us) | Композиция и способ для местного применения и чрескожного введения ботулинового токсина |
| RU2007136617A (ru) | 2005-03-03 | 2009-04-10 | Риванс Терапьютикс, Инк. (Us) | Композиция и способ для местного применения и чрезкожного введения олигопептида |
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| EP1935434A1 (en) * | 2006-12-19 | 2008-06-25 | Novosom AG | Construction and use of transfection enhancer elements |
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| EP2143726A1 (en) * | 2008-07-11 | 2010-01-13 | Novosom AG | Nucleic acid comprising zwitterionic nucleotides |
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| BRPI1015295A2 (pt) | 2009-04-20 | 2016-05-31 | Angiochem Inc | traamento de câncer de ovário usando um agente anticâncer conjugado a um análogo angiopep-2. |
| CN102803500B (zh) | 2009-06-05 | 2014-11-19 | 13治疗有限公司 | 免疫调节肽和使用方法 |
| BRPI1015918A2 (pt) | 2009-07-02 | 2019-09-24 | Angiochem Inc | conjugados de peptídeo multiméricos e usos dos mesmos |
| KR102095478B1 (ko) | 2010-05-28 | 2020-04-01 | 사렙타 쎄러퓨틱스, 인코퍼레이티드 | 변형된 서브유니트간 결합 및/또는 말단 그룹을 갖는 올리고뉴클레오타이드 유사체 |
| US10017763B2 (en) | 2010-09-03 | 2018-07-10 | Sarepta Therapeutics, Inc. | dsRNA molecules comprising oligonucleotide analogs having modified intersubunit linkages and/or terminal groups |
| WO2012138879A2 (en) | 2011-04-06 | 2012-10-11 | 13Therapeutics, Inc. | Peptides for the treatment of hearing |
| US20130085139A1 (en) | 2011-10-04 | 2013-04-04 | Royal Holloway And Bedford New College | Oligomers |
| AU2012340390B2 (en) | 2011-11-18 | 2016-11-24 | Sarepta Therapeutics, Inc. | Functionally-modified oligonucleotides and subunits thereof |
| WO2013142087A1 (en) | 2012-03-20 | 2013-09-26 | Sarepta Therapeutics, Inc. | Boronic acid conjugates of oligonucleotide analogues |
| GB201210358D0 (en) * | 2012-06-12 | 2012-07-25 | Polytherics Ltd | Complexes |
| AU2013302270A1 (en) | 2012-08-14 | 2015-03-26 | Angiochem Inc. | Peptide-dendrimer conjugates and uses thereof |
| MA41795A (fr) | 2015-03-18 | 2018-01-23 | Sarepta Therapeutics Inc | Exclusion d'un exon induite par des composés antisens dans la myostatine |
| WO2016196897A1 (en) | 2015-06-04 | 2016-12-08 | Sarepta Therapeutics, Inc. | Methods and compounds for treatment of lymphocyte-related diseases and conditions |
| JP6823055B2 (ja) | 2015-06-15 | 2021-01-27 | アンジオケム インコーポレーテッド | 軟髄膜癌腫症の治療方法 |
| EP3377067A4 (en) * | 2015-10-07 | 2019-07-31 | Cormedix Inc. | SKIN-PENETRATING FORMULATION OF TAUROLIDINE |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1541436A (en) * | 1976-02-02 | 1979-02-28 | Searle & Co | Immunological materials |
| GB9017024D0 (en) * | 1990-08-03 | 1990-09-19 | Erba Carlo Spa | New linker for bioactive agents |
| GB9026491D0 (en) * | 1990-12-05 | 1991-01-23 | Erba Carlo Spa | Anthracycline-conjugates |
| CA2250295C (en) * | 1996-03-12 | 2008-12-30 | Pg-Txl Company L.P. | Water soluble paclitaxel prodrugs |
-
1997
- 1997-04-30 EP EP97923513A patent/EP0966303A2/en not_active Withdrawn
- 1997-04-30 AU AU29298/97A patent/AU729643B2/en not_active Ceased
- 1997-04-30 WO PCT/US1997/007335 patent/WO1997040854A2/en active Application Filing
- 1997-04-30 CA CA002252706A patent/CA2252706A1/en not_active Abandoned
- 1997-04-30 JP JP9539221A patent/JP2000509394A/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997040854A3 (en) | 1998-03-12 |
| JP2000509394A (ja) | 2000-07-25 |
| WO1997040854A2 (en) | 1997-11-06 |
| AU729643B2 (en) | 2001-02-08 |
| AU2929897A (en) | 1997-11-19 |
| EP0966303A2 (en) | 1999-12-29 |
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