CA2252422A1 - Procede et reactifs servant a moduler l'apoptose - Google Patents

Procede et reactifs servant a moduler l'apoptose Download PDF

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Publication number
CA2252422A1
CA2252422A1 CA 2252422 CA2252422A CA2252422A1 CA 2252422 A1 CA2252422 A1 CA 2252422A1 CA 2252422 CA2252422 CA 2252422 CA 2252422 A CA2252422 A CA 2252422A CA 2252422 A1 CA2252422 A1 CA 2252422A1
Authority
CA
Canada
Prior art keywords
bap31
cell
polypeptide
protein
apoptosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2252422
Other languages
English (en)
Inventor
Gordon C. Shore
W. H. Florence Ng
Mai Nguyen
Philip E. Branton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
McGill University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA002198988A external-priority patent/CA2198988A1/fr
Application filed by Individual filed Critical Individual
Priority to CA 2252422 priority Critical patent/CA2252422A1/fr
Publication of CA2252422A1 publication Critical patent/CA2252422A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747Apoptosis related proteins
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne une nouvelle protéine de l'apoptose, la protéine p28 Bap31, des fragments polypeptidiques de celle-ci, des molécules d'acide nucléique antisens de cette protéine p28 Bap31, ainsi que des anticorps dirigés contre celle-ci. L'invention concerne également des procédés servant à moduler l'apoptose et à détecter des composés modulant celle-ci.
CA 2252422 1997-03-03 1998-03-02 Procede et reactifs servant a moduler l'apoptose Abandoned CA2252422A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA 2252422 CA2252422A1 (fr) 1997-03-03 1998-03-02 Procede et reactifs servant a moduler l'apoptose

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA2,198,988 1997-03-03
CA002198988A CA2198988A1 (fr) 1997-03-03 1997-03-03 Proteine p28 bap31 associee a la bcl-2 et utilisation de cette derniere pour la modulation de l'apoptose
CA 2252422 CA2252422A1 (fr) 1997-03-03 1998-03-02 Procede et reactifs servant a moduler l'apoptose

Publications (1)

Publication Number Publication Date
CA2252422A1 true CA2252422A1 (fr) 1998-09-11

Family

ID=25679079

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2252422 Abandoned CA2252422A1 (fr) 1997-03-03 1998-03-02 Procede et reactifs servant a moduler l'apoptose

Country Status (1)

Country Link
CA (1) CA2252422A1 (fr)

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead