CA2249323A1 - Solid phase lipoglycopeptide library, compositions and methods - Google Patents

Solid phase lipoglycopeptide library, compositions and methods Download PDF

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Publication number
CA2249323A1
CA2249323A1 CA002249323A CA2249323A CA2249323A1 CA 2249323 A1 CA2249323 A1 CA 2249323A1 CA 002249323 A CA002249323 A CA 002249323A CA 2249323 A CA2249323 A CA 2249323A CA 2249323 A1 CA2249323 A1 CA 2249323A1
Authority
CA
Canada
Prior art keywords
group
mmol
library
bond
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002249323A
Other languages
English (en)
French (fr)
Inventor
Michael Sofia
Dashan Liu
Tin Yau Chan
Anna Chen
Nigel Allanson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aeolus Pharmaceuticals Inc
Original Assignee
Transcell Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transcell Technologies Inc filed Critical Transcell Technologies Inc
Publication of CA2249323A1 publication Critical patent/CA2249323A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Analytical Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002249323A 1996-03-21 1997-03-21 Solid phase lipoglycopeptide library, compositions and methods Abandoned CA2249323A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US1377796P 1996-03-21 1996-03-21
US60/013,777 1996-03-21
US2452896P 1996-08-26 1996-08-26
US60/024,528 1996-08-26

Publications (1)

Publication Number Publication Date
CA2249323A1 true CA2249323A1 (en) 1997-09-25

Family

ID=26685236

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002249323A Abandoned CA2249323A1 (en) 1996-03-21 1997-03-21 Solid phase lipoglycopeptide library, compositions and methods

Country Status (5)

Country Link
EP (1) EP0934076A1 (enrdf_load_stackoverflow)
JP (1) JP2000507246A (enrdf_load_stackoverflow)
AU (1) AU2341197A (enrdf_load_stackoverflow)
CA (1) CA2249323A1 (enrdf_load_stackoverflow)
WO (1) WO1997034623A1 (enrdf_load_stackoverflow)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19624345B4 (de) * 1996-06-19 2004-12-23 Südzucker AG Mannheim/Ochsenfurt Acylierte Kohlenhydrate mit mindestens einer mit dem Kohlenhydrat veretherten Carboxyalkyl-Gruppe, Verfahren zu deren Herstellung und deren Verwendung in Waschmitteln
DE19642751A1 (de) * 1996-10-16 1998-04-23 Deutsches Krebsforsch Saccharid-Bibliothek
JP4362017B2 (ja) 1998-12-23 2009-11-11 セラヴァンス， インコーポレーテッド グリコペプチド誘導体およびそれを含有する薬学的組成物
US20010051349A1 (en) 2000-02-17 2001-12-13 Glycominds Ltd. Combinatorial complex carbohydrate libraries and methods for the manufacture and uses thereof
US7138531B2 (en) * 2001-10-15 2006-11-21 Kemin Pharma B.V.B.A. Preparation and use of carbohydrate-based bicyclic ring structures with antimicrobial and cytostatic activity
AUPS213802A0 (en) * 2002-05-03 2002-06-06 Alchemia Pty Ltd Disaccharides for drug discovery
AU2002952121A0 (en) 2002-10-17 2002-10-31 Alchemia Limited Novel carbohydrate based anti-bacterials
CN101278079B (zh) 2005-10-04 2012-09-19 阿尔卡米亚有限公司 药物设计方法
EP3608330B1 (en) 2008-12-16 2022-11-09 Genzyme Corporation Synthetic intermediates for preparing oligosaccharide-protein conjugates
CN113200935B (zh) * 2021-04-26 2022-07-08 威海海洋生物医药产业技术研究院有限公司 一种用于次氯酸检测的荧光探针及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995018971A1 (en) * 1994-01-11 1995-07-13 Affymax Technologies N.V. Methods for the solid phase synthesis of glycoconjugates

Also Published As

Publication number Publication date
AU2341197A (en) 1997-10-10
EP0934076A4 (enrdf_load_stackoverflow) 1999-08-11
WO1997034623A1 (en) 1997-09-25
EP0934076A1 (en) 1999-08-11
JP2000507246A (ja) 2000-06-13

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