CA2248684A1 - Immunite contre les especes trypanosomatides - Google Patents
Immunite contre les especes trypanosomatides Download PDFInfo
- Publication number
- CA2248684A1 CA2248684A1 CA002248684A CA2248684A CA2248684A1 CA 2248684 A1 CA2248684 A1 CA 2248684A1 CA 002248684 A CA002248684 A CA 002248684A CA 2248684 A CA2248684 A CA 2248684A CA 2248684 A1 CA2248684 A1 CA 2248684A1
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- Prior art keywords
- gene
- leishmania
- trypanosomatid
- protein
- mrna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- BPHPUYQFMNQIOC-NXRLNHOXSA-N isopropyl beta-D-thiogalactopyranoside Chemical compound CC(C)S[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O BPHPUYQFMNQIOC-NXRLNHOXSA-N 0.000 description 1
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- RGCLLPNLLBQHPF-HJWRWDBZSA-N phosphamidon Chemical compound CCN(CC)C(=O)C(\Cl)=C(/C)OP(=O)(OC)OC RGCLLPNLLBQHPF-HJWRWDBZSA-N 0.000 description 1
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- 239000002342 ribonucleoside Substances 0.000 description 1
- 229920002477 rna polymer Polymers 0.000 description 1
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- KSAVQLQVUXSOCR-UHFFFAOYSA-M sodium lauroyl sarcosinate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O KSAVQLQVUXSOCR-UHFFFAOYSA-M 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
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- 238000007920 subcutaneous administration Methods 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
La présente invention porte sur des histones de trypanosomatides se présentant sous une forme pratiquement isolée, et destinées à être utilisées comme antigènes de protection contre l'infection par les trypanosomatides. Ces histones peuvent être soit isolées du parasite correspondant, soit obtenues au moyen de techniques de recombinaison d'ADN. Concernant la production, l'invention porte également sur des gènes codant des histones, ainsi que sur des dérivés des gènes, comme d'autres acides nucléiques et des produits géniques tels que des peptides et des protéines. L'invention porte enfin sur des examens diagnostiques, des compositions pharmaceutiques et des vaccins renfermant les excipients et/ou adjuvants habituels et au moins une histone, un gène codant une histone ou un dérivé de celui-ci.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96200665.6 | 1996-03-12 | ||
| EP96200665 | 1996-03-12 | ||
| EP96201343.9 | 1996-05-15 | ||
| EP96201343 | 1996-05-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2248684A1 true CA2248684A1 (fr) | 1997-09-18 |
Family
ID=26142593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002248684A Abandoned CA2248684A1 (fr) | 1996-03-12 | 1997-03-12 | Immunite contre les especes trypanosomatides |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0896623A1 (fr) |
| JP (1) | JP2000507098A (fr) |
| CN (1) | CN1216584A (fr) |
| AU (1) | AU733720B2 (fr) |
| BR (1) | BR9708188A (fr) |
| CA (1) | CA2248684A1 (fr) |
| IL (1) | IL126145A0 (fr) |
| MA (1) | MA25182A1 (fr) |
| NZ (1) | NZ331889A (fr) |
| TN (1) | TNSN97045A1 (fr) |
| TR (1) | TR199801776T2 (fr) |
| WO (1) | WO1997033999A1 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0416246B8 (pt) * | 2003-11-05 | 2021-05-25 | C B F Leti S L Unipersonal | usos de todas as quatro histonas de leishmania h2a, h2b, h3 ou h4, de um vetor e de anticorpos, composição farmacêutica e agente ou kit diagnóstico |
| FR2952382B1 (fr) * | 2009-11-10 | 2011-11-25 | Univ Victor Segalen Bordeaux 2 | Vaccins et diagnostics contre les trypanosomoses animales africaines |
| BRPI1003744B1 (pt) * | 2010-06-08 | 2021-10-26 | Universidade Federal De Ouro Preto | E-ntpdases recombinantes, uso na produção de kit de diagnóstico para detecção de anticorpos nas leishmanioses causadas por espécies do gênero leishmania |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8722741D0 (en) * | 1987-09-28 | 1987-11-04 | Hoffmann La Roche | Induction of cytotoxic t cell response |
-
1997
- 1997-03-11 TN TNTNSN97045A patent/TNSN97045A1/fr unknown
- 1997-03-11 MA MA24516A patent/MA25182A1/fr unknown
- 1997-03-12 NZ NZ331889A patent/NZ331889A/xx unknown
- 1997-03-12 WO PCT/EP1997/001289 patent/WO1997033999A1/fr not_active Application Discontinuation
- 1997-03-12 CA CA002248684A patent/CA2248684A1/fr not_active Abandoned
- 1997-03-12 AU AU20272/97A patent/AU733720B2/en not_active Ceased
- 1997-03-12 BR BR9708188-4A patent/BR9708188A/pt not_active IP Right Cessation
- 1997-03-12 CN CN97193835A patent/CN1216584A/zh active Pending
- 1997-03-12 TR TR1998/01776T patent/TR199801776T2/xx unknown
- 1997-03-12 IL IL12614597A patent/IL126145A0/xx unknown
- 1997-03-12 EP EP97908233A patent/EP0896623A1/fr not_active Withdrawn
- 1997-03-12 JP JP9532298A patent/JP2000507098A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP2000507098A (ja) | 2000-06-13 |
| NZ331889A (en) | 2000-12-22 |
| MA25182A1 (fr) | 2001-07-02 |
| CN1216584A (zh) | 1999-05-12 |
| AU733720B2 (en) | 2001-05-24 |
| IL126145A0 (en) | 1999-05-09 |
| BR9708188A (pt) | 2000-01-18 |
| WO1997033999A1 (fr) | 1997-09-18 |
| TR199801776T2 (xx) | 1998-12-21 |
| TNSN97045A1 (fr) | 2005-03-15 |
| AU2027297A (en) | 1997-10-01 |
| EP0896623A1 (fr) | 1999-02-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |