CA2244673A1 - Peptides inhibiteurs de la proliferation de cellules hematopoietiques - Google Patents

Peptides inhibiteurs de la proliferation de cellules hematopoietiques Download PDF

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Publication number
CA2244673A1
CA2244673A1 CA002244673A CA2244673A CA2244673A1 CA 2244673 A1 CA2244673 A1 CA 2244673A1 CA 002244673 A CA002244673 A CA 002244673A CA 2244673 A CA2244673 A CA 2244673A CA 2244673 A1 CA2244673 A1 CA 2244673A1
Authority
CA
Canada
Prior art keywords
lys
asp
ser
pro
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002244673A
Other languages
English (en)
Inventor
Josiane Thierry
Joanna Wdzieczak-Bakala
Pierre Potier
Maryse Lenfant
Catherine Grillon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A. ( A.S.)
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2244673A1 publication Critical patent/CA2244673A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Cette invention se rapporte à des dérivés de tétrapeptides Ser-Asp-Lys-Pro et à l'utilisation de ceux-ci pour inhiber la prolifération de cellules hématopoïétiques.
CA002244673A 1996-02-01 1997-01-31 Peptides inhibiteurs de la proliferation de cellules hematopoietiques Abandoned CA2244673A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US59536196A 1996-02-01 1996-02-01
US08/595,361 1996-02-01
US75451196A 1996-11-19 1996-11-19
US08/754,511 1996-11-19

Publications (1)

Publication Number Publication Date
CA2244673A1 true CA2244673A1 (fr) 1997-08-07

Family

ID=27082249

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002244673A Abandoned CA2244673A1 (fr) 1996-02-01 1997-01-31 Peptides inhibiteurs de la proliferation de cellules hematopoietiques

Country Status (7)

Country Link
EP (1) EP0877753A1 (fr)
JP (1) JP2002515864A (fr)
AU (1) AU721261B2 (fr)
CA (1) CA2244673A1 (fr)
IL (1) IL125509A0 (fr)
PL (1) PL328081A1 (fr)
WO (1) WO1997028183A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2814076B1 (fr) 2000-09-21 2002-12-20 Centre Nat Rech Scient Agent angiogenique et ses utilisations
FR2872040B1 (fr) 2004-06-23 2006-09-22 Centre Nat Rech Scient Cnrse Utilisation cosmetique d'au moins un tetrapeptide naturel ac-n-ser-asp-lys-pro- ou un de ses analogues en tant qu'agent antivieillissement et restructurant de la peau
FR2882256B1 (fr) 2005-02-18 2007-05-25 Centre Nat Rech Scient Utilisation cosmetique d'au moins un tetrapeptide naturel ac-n-ser-asp-lys-pro- ou un de ses analogues en tant qu'agent pour ralentir la chute des cheveux et/ou stimuler leur croissance
KR101335203B1 (ko) * 2010-03-26 2013-11-29 숙명여자대학교산학협력단 혈관신생촉진용 펩타이드 및 이의 용도
US9428552B2 (en) 2012-11-19 2016-08-30 Wellstat Therapeutics Corporation Stem cell mobilization and tissue repair and regeneration
FR3120794B1 (fr) 2021-03-16 2023-11-24 Rpm Dermatologie Composition pour injection comprenant un conjugué peptidique

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601678B1 (fr) * 1986-07-18 1989-11-24 Inst Nat Sante Rech Med Peptides comprenant la sequence seryl-aspartyl-lysyl-prolyle, procede pour l'extraction du tetrapeptide correspondant, et applications, notamment a la protection de la moelle osseuse au cours de traitements anticancereux par la chimiotherapie
DE4224509C2 (de) * 1992-07-24 1995-04-20 Ruhenstroth Bauer Gerhard Prof Wirkstoff zur Hemmung der Proliferationsrate von Leberzellen

Also Published As

Publication number Publication date
JP2002515864A (ja) 2002-05-28
PL328081A1 (en) 1999-01-04
AU721261B2 (en) 2000-06-29
WO1997028183A1 (fr) 1997-08-07
IL125509A0 (en) 1999-03-12
AU1807597A (en) 1997-08-22
EP0877753A1 (fr) 1998-11-18

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Legal Events

Date Code Title Description
FZDE Discontinued