CA2243320A1 - Inhibiteurs de la farnesyle transferase - Google Patents

Inhibiteurs de la farnesyle transferase Download PDF

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Publication number
CA2243320A1
CA2243320A1 CA 2243320 CA2243320A CA2243320A1 CA 2243320 A1 CA2243320 A1 CA 2243320A1 CA 2243320 CA2243320 CA 2243320 CA 2243320 A CA2243320 A CA 2243320A CA 2243320 A1 CA2243320 A1 CA 2243320A1
Authority
CA
Canada
Prior art keywords
hydrogen
substituted
alkyl
aryl
unsubstituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2243320
Other languages
English (en)
Inventor
Christopher J. Dinsmore
George D. Hartman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9605708.8A external-priority patent/GB9605708D0/en
Application filed by Individual filed Critical Individual
Priority claimed from PCT/US1997/001354 external-priority patent/WO1997027852A1/fr
Publication of CA2243320A1 publication Critical patent/CA2243320A1/fr
Abandoned legal-status Critical Current

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Abstract

La présente invention se rapporte à des composés qui inhibent la farnésyle transférase (Ftase) ainsi que la farnésylation de la protéine oncogène Ras. L'invention se rapporte en outre à des compositions chimiothérapeutiques contenant les composés de cette invention et à des procédés destinés à inhiber la farnésyle transférase ainsi que la farnésylation de la protéine oncogène Ras.
CA 2243320 1996-01-30 1997-01-27 Inhibiteurs de la farnesyle transferase Abandoned CA2243320A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US1079896P 1996-01-30 1996-01-30
US60/010,798 1996-01-30
GB9605708.8 1996-03-19
GBGB9605708.8A GB9605708D0 (en) 1996-03-19 1996-03-19 Inhibitors of farnesyl-protein transferase
PCT/US1997/001354 WO1997027852A1 (fr) 1996-01-30 1997-01-27 Inhibiteurs de la farnesyle transferase

Publications (1)

Publication Number Publication Date
CA2243320A1 true CA2243320A1 (fr) 1997-08-07

Family

ID=29424171

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2243320 Abandoned CA2243320A1 (fr) 1996-01-30 1997-01-27 Inhibiteurs de la farnesyle transferase

Country Status (1)

Country Link
CA (1) CA2243320A1 (fr)

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Legal Events

Date Code Title Description
FZDE Dead