CA2231803C - Lipid extract having anti-inflammatory activity - Google Patents

Lipid extract having anti-inflammatory activity Download PDF

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Publication number
CA2231803C
CA2231803C CA002231803A CA2231803A CA2231803C CA 2231803 C CA2231803 C CA 2231803C CA 002231803 A CA002231803 A CA 002231803A CA 2231803 A CA2231803 A CA 2231803A CA 2231803 C CA2231803 C CA 2231803C
Authority
CA
Canada
Prior art keywords
lipid extract
use according
supercritical fluid
pco
fluid extraction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002231803A
Other languages
English (en)
French (fr)
Other versions
CA2231803A1 (en
Inventor
Theodore Macrides
Nicolette Kalafatis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmalink International Ltd
Original Assignee
Pharmalink International Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmalink International Ltd filed Critical Pharmalink International Ltd
Publication of CA2231803A1 publication Critical patent/CA2231803A1/en
Application granted granted Critical
Publication of CA2231803C publication Critical patent/CA2231803C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/57Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
CA002231803A 1995-09-11 1996-09-10 Lipid extract having anti-inflammatory activity Expired - Lifetime CA2231803C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPN5311A AUPN531195A0 (en) 1995-09-11 1995-09-11 Lipid extract having anti-inflamatory activity
AUPN5311/95 1995-09-11
PCT/AU1996/000564 WO1997009992A1 (en) 1995-09-11 1996-09-10 Lipid extract having anti-inflammatory activity

Publications (2)

Publication Number Publication Date
CA2231803A1 CA2231803A1 (en) 1997-03-20
CA2231803C true CA2231803C (en) 2004-11-23

Family

ID=3789640

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002231803A Expired - Lifetime CA2231803C (en) 1995-09-11 1996-09-10 Lipid extract having anti-inflammatory activity

Country Status (12)

Country Link
US (2) US6083536A (enExample)
EP (1) EP0850068B1 (enExample)
JP (1) JP4101876B2 (enExample)
AT (1) ATE293984T1 (enExample)
AU (1) AUPN531195A0 (enExample)
CA (1) CA2231803C (enExample)
DE (1) DE69634666T2 (enExample)
DK (1) DK0850068T3 (enExample)
ES (1) ES2241001T3 (enExample)
PT (1) PT850068E (enExample)
WO (1) WO1997009992A1 (enExample)
ZA (1) ZA967626B (enExample)

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AUPN531195A0 (en) * 1995-09-11 1995-10-05 J.W. Broadbent Nominees Pty. Ltd. Lipid extract having anti-inflamatory activity
CN1265566A (zh) 1997-06-04 2000-09-06 细胞改良有限公司 破碎生物材料的方法和装置
SE9703085D0 (sv) * 1997-08-27 1997-08-27 Micro Active Protein In Sweden Anti-microbial composition
US6946144B1 (en) 1998-07-08 2005-09-20 Oryxe Transdermal delivery system
US7220427B2 (en) 1998-07-08 2007-05-22 Oryxe Mixture for transdermal delivery of low and high molecular weight compounds
DE19838794A1 (de) * 1998-08-26 2000-03-09 Aristavet Veterinaerspezialita Zusammensetzung zur Behandlung von Osteoarthritis und zur nutritiven Behandlung des Gelenkknorpels
AUPP910699A0 (en) * 1999-03-10 1999-04-01 Pharmalink International Limited Inhibitor of lipoxygenase pathways
US6596303B1 (en) * 1999-03-22 2003-07-22 Mars Incorporated Pet food for maintenance of joint health and alleviation of arthritic symptoms in companion animals
AU2005200953B2 (en) * 1999-03-22 2007-07-12 Mars, Incorporated Pet food for maintenance of joint health and alleviation of arthritic symptoms in companion animals and method of manufacturing same
US20020018787A1 (en) * 1999-05-21 2002-02-14 Roger V. Kendall Methods and compositions for modulating immune response and for the treatment of inflammatory disease
EP1408999B1 (en) * 1999-07-21 2008-03-12 Bomac Research Limited Compositions addressing inflammation and/or degenerative disorders
ATE270558T1 (de) * 1999-08-26 2004-07-15 Ganeden Biotech Inc Verwendung von emu-öl als träger für fungizide, antibakterielle und antivirale arzneien
AUPR030800A0 (en) * 2000-09-22 2000-10-12 Pharmalink International Limited Immunomodulatory preparation
AU9347701A (en) * 2000-09-22 2002-04-02 Pharmalink Internat Ltd Immunomodulatory preparation
US7519546B2 (en) * 2001-04-30 2009-04-14 General Electric Company Maintaining synchronization of information published to multiple subscribers
EP1417211B1 (en) 2001-07-27 2007-05-30 Neptune Technologies & Bioressources Inc. Natural phospholipids of marine origin containing flavonoids and polyunsaturated phospholipids and their uses
AUPS082102A0 (en) * 2002-03-01 2002-03-21 Women's And Children's Hospital Therapeutic properties of oils
WO2003077811A1 (en) * 2002-03-14 2003-09-25 Mcclung Jackie H Pharmaceutically active compounds containing phosphorous defficient oil
DE20210182U1 (de) * 2002-07-01 2002-10-02 Bio-Innovation Development Ltd., Christchurch Wirkstoffzusammensetzung aus Bestandteilen der Grünlippenmuschel (perna canaliculus) und zusätzlichen Omega-3-Fettsäuren
US20040228926A1 (en) * 2003-03-14 2004-11-18 Kendall Roger V. Methods for treating cancer using perna canaliculus component(S) and extracts of perna canaliculus
US7052715B2 (en) * 2003-04-11 2006-05-30 All Natural Fmg, Inc. Alcohol-free transdermal analgesic composition and processes for manufacture and use thereof
US7033998B2 (en) * 2003-04-11 2006-04-25 All Natural Fmg, Inc. Alcohol-free transdermal insulin composition and processes for manufacture and use thereof
WO2005073354A1 (en) * 2004-01-30 2005-08-11 Bionovate Limited Solvent extraction of lipids such as essential fatty acids
GB0411165D0 (en) * 2004-05-19 2004-06-23 Bionovate Ltd Hyaluronic acid containing pharmaceutical or veterinary compounds
GB0411166D0 (en) * 2004-05-19 2004-06-23 Bionovate Ltd Treatment for asthma and arthritis
US20060039992A1 (en) * 2004-06-02 2006-02-23 Miller Bruce A Jr Novel compositions and methods utilizing green-lipped mussel and fatty acids
WO2006052150A1 (en) * 2004-11-15 2006-05-18 University Of Otago Mussel extract composition with enhanced anti-inflammatory activity
US8092839B2 (en) * 2004-12-13 2012-01-10 Swing Aerobics Licensing, Inc. Medicament for treatment of cancer and other diseases
US8431165B2 (en) * 2004-12-13 2013-04-30 Swing Aerobics Licensing, Inc. Medicament for treatment of cancer and other diseases
WO2006128244A1 (en) * 2005-06-03 2006-12-07 Mc Farlane Marketing (Aust.) Pty. Ltd. Lipid extract of mussels and method for preparation thereof
NZ547429A (en) * 2006-05-24 2009-09-25 Ind Res Ltd Extraction of highly unsaturated lipids with liquid dimethyl ether
US20090238763A1 (en) * 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
CN101489985B (zh) 2006-07-18 2014-01-08 天津昕晨泰飞尔医药科技有限公司 具有快速皮肤穿透率的带正电荷的水溶性布洛芬前药
PL2046727T3 (pl) 2006-07-25 2014-08-29 Techfields Biochem Co Ltd Dodatnio naładowane rozpuszczalne w wodzie proleki diklofenaku o bardzo szybkim stopniu przenikania przez skórę
EP2990402A1 (en) 2006-08-08 2016-03-02 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of aryl- and heteroarylacetic acids with very fast skin penetration rate
EP2061749B1 (en) 2006-09-03 2018-02-21 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of acetaminophen and related compounds with very fast skin penetration rate
CN101506168B (zh) 2006-09-03 2014-12-10 于崇曦 具有快速皮肤穿透速度的带正电荷的水溶性的芳基邻氨基苯甲酸的前药
WO2008035756A1 (en) * 2006-09-22 2008-03-27 Heimat Co., Ltd. Anti-angiogenic composition comprising extract having anti-angiogenic activity and lecithin
ES2466346T3 (es) * 2006-10-02 2014-06-10 Techfields Biochem Co. Ltd Profármacos de prostaglandinas solubles en agua con carga positiva y compuestos relacionados con índices de penetración en la piel muy altos
JP5378221B2 (ja) 2006-10-11 2013-12-25 テックフィールズ バイオケム カンパニー リミテッド 非常に高い皮膚浸透率を有するオキシカム及び関連化合物の正荷電水溶性プロドラッグ
NZ552238A (en) * 2006-12-20 2009-07-31 Seperex Nutritionals Ltd An extract
US8337916B2 (en) * 2007-06-01 2012-12-25 Laila Nutraceuticals Use of Aphanamixis polystacha extracts or fractions against 5-lipoxygenase mediated diseases
WO2008149181A1 (en) * 2007-06-04 2008-12-11 Techfields Inc Pro-drugs of nsaias with very high skin and membranes penetration rates and their new medicinal uses
MX340963B (es) * 2008-04-28 2016-07-29 Vermont Italia Srl Formulacion farmaceutica que contiene palmitoil etanolamida y estearoil etanolamida.
WO2010065936A1 (en) 2008-12-04 2010-06-10 Chongxi Yu High penetration compositions and their applications
JP5313064B2 (ja) * 2009-07-03 2013-10-09 株式会社ノエビア 中性脂肪蓄積促進剤、豊胸剤
CN104540504A (zh) 2012-01-18 2015-04-22 苏州泰飞尔医药有限公司 治疗肺部疾病的高穿透力前药组合物和医药组合物
SG11201505076UA (en) 2012-12-31 2015-07-30 Jrx Biotechnology Inc Liquid topical pharmaceutical nano-emulsion formulations
JP6176655B2 (ja) * 2013-07-02 2017-08-09 御木本製薬株式会社 マトリックスメタロプロテアーゼ活性阻害剤、皮膚外用剤、老化防止用皮膚外用剤、シワ防止用皮膚外用剤、慢性関節リウマチ及び他の疾患の治療又は予防剤
SG11201800440SA (en) * 2015-07-20 2018-02-27 Bengt I Samuelsson Institute Of Life Science Res Mussel adhesive protein product and applications thereof in suppression of skin inflammations
KR20180053318A (ko) 2015-09-17 2018-05-21 제이알엑스 바이오테크놀로지, 인코포레이티드 피부 수화 또는 보습을 향상시키기 위한 접근법
AR110560A1 (es) * 2016-12-20 2019-04-10 Sanford Ltd Extractos y/o composiciones bioactivas de mejillones
CN111432654A (zh) * 2017-12-04 2020-07-17 雾凇科技有限公司 从甲壳类捕获物中生产蛋白质磷脂复合物的方法
PL3727404T3 (pl) * 2017-12-22 2024-01-29 Pharmalink International Limited Kompozycje zawierające ekstrakt lipidowy z małży i olej z kryla oraz ich zastosowania medyczne
KR20220131272A (ko) 2020-01-21 2022-09-27 린트벨스 리미티드 상승효과가 있는 조성물
CN113041263B (zh) * 2021-03-15 2023-07-25 青岛大学 一种贻贝功能性脂质在制备治疗2型糖尿病产品中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
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DE2965855D1 (en) * 1978-09-25 1983-08-18 Farlane Stuart John Mc Pharmaceutical preparations containing a mollusc extract
US4801453A (en) 1984-05-01 1989-01-31 James M. Broadbent Stabilized mussel extract
AUPM740594A0 (en) 1994-08-11 1994-09-01 J.W. Broadbent Nominees Pty. Ltd. Anti-inflammatory preparation
AU3156595A (en) * 1994-08-11 1996-03-07 J.W. Broadbent Nominees Pty. Ltd. Anti-inflammatory preparation
AUPN531195A0 (en) * 1995-09-11 1995-10-05 J.W. Broadbent Nominees Pty. Ltd. Lipid extract having anti-inflamatory activity

Also Published As

Publication number Publication date
EP0850068A4 (en) 2000-09-13
ZA967626B (en) 1997-09-03
ES2241001T3 (es) 2005-10-16
EP0850068B1 (en) 2005-04-27
US6083536A (en) 2000-07-04
US6346278B1 (en) 2002-02-12
CA2231803A1 (en) 1997-03-20
JP4101876B2 (ja) 2008-06-18
DE69634666T2 (de) 2006-04-27
JPH11512400A (ja) 1999-10-26
AUPN531195A0 (en) 1995-10-05
DE69634666D1 (de) 2005-06-02
PT850068E (pt) 2005-08-31
EP0850068A1 (en) 1998-07-01
DK0850068T3 (da) 2005-08-15
ATE293984T1 (de) 2005-05-15
WO1997009992A1 (en) 1997-03-20

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Effective date: 20160912