CA2230160A1 - Antimicrobial cationic peptides and methods of screening for the same - Google Patents
Antimicrobial cationic peptides and methods of screening for the same Download PDFInfo
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- CA2230160A1 CA2230160A1 CA002230160A CA2230160A CA2230160A1 CA 2230160 A1 CA2230160 A1 CA 2230160A1 CA 002230160 A CA002230160 A CA 002230160A CA 2230160 A CA2230160 A CA 2230160A CA 2230160 A1 CA2230160 A1 CA 2230160A1
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- 239000008158 vegetable oil Substances 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 150000003952 β-lactams Chemical class 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US268795P | 1995-08-23 | 1995-08-23 | |
| US60/002,687 | 1995-08-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2230160A1 true CA2230160A1 (en) | 1997-03-06 |
Family
ID=21701983
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002230160A Abandoned CA2230160A1 (en) | 1995-08-23 | 1996-08-23 | Antimicrobial cationic peptides and methods of screening for the same |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6191254B1 (https=) |
| EP (1) | EP0846128B1 (https=) |
| JP (1) | JP3860838B2 (https=) |
| AT (1) | ATE412668T1 (https=) |
| AU (1) | AU6940796A (https=) |
| CA (1) | CA2230160A1 (https=) |
| DE (1) | DE69637731D1 (https=) |
| ES (1) | ES2316154T3 (https=) |
| WO (1) | WO1997008199A2 (https=) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1174439B1 (en) * | 1996-08-21 | 2008-10-08 | Migenix Inc. | Compositions and methods for treating infections using analogues of indolicidin |
| US6503881B2 (en) * | 1996-08-21 | 2003-01-07 | Micrologix Biotech Inc. | Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics |
| US6180604B1 (en) * | 1996-08-21 | 2001-01-30 | Micrologix Biotech Inc. | Compositions and methods for treating infections using analogues of indolicidin |
| US6303575B1 (en) | 1998-05-12 | 2001-10-16 | The Regents Of The University Of California | Indolicidin analogs and methods of using same |
| US6444645B1 (en) | 1998-06-18 | 2002-09-03 | The Regents Of The University Of California | Crosslink-stabilized indolicidin analogs |
| US6288212B1 (en) * | 1998-08-28 | 2001-09-11 | The University Of British Columbia | Anti-endotoxic, antimicrobial cationic peptides and methods of use therefor |
| BR9914922A (pt) * | 1998-10-30 | 2001-07-10 | Interlink Biotechnologies Llc | Métodos para reduzir a extensão de degradação de protease de uma proteìna aplicada a ou produzida por uma planta, para inibir o crescimento de um patógeno vegetal e para produzir uma planta, peptìdeo, molécula de ácido nucleico, segmento de ácido nucleico, construção de ácido nucleico, planta transgênica, semente, célula vegetal, e, composição para o uso na proteção de um peptìdeo, polipeptìdeo ou proteìna da degradação da protease. |
| US6946261B1 (en) * | 1998-11-20 | 2005-09-20 | Migenix Inc. | Efficient methods for producing anti-microbial cationic peptides in host cells |
| US6335318B1 (en) | 1999-05-10 | 2002-01-01 | The Regents Of The University Of California | Antimicrobial theta defensins and methods of using same |
| US6497676B1 (en) | 2000-02-10 | 2002-12-24 | Baxter International | Method and apparatus for monitoring and controlling peritoneal dialysis therapy |
| US6337317B1 (en) | 2000-06-27 | 2002-01-08 | The University Of British Columbia | Antimicrobial peptides and methods of use thereof |
| US6835536B2 (en) | 2001-08-21 | 2004-12-28 | Micrologix Biotech Inc. | Antimicrobial cationic peptides and formulations thereof |
| AU2002328203C1 (en) | 2001-08-24 | 2009-01-08 | Migenix Inc. | Antimicrobial and anti-inflammatory peptides |
| KR100438416B1 (ko) * | 2001-09-19 | 2004-07-02 | 학교법인조선대학교 | Ｃａ－ｍａ 펩타이드의 아미노산 중 하나 또는 그 이상을치환하여 ＋ 전극과 소수성 영역이 증가된 신규한펩타이드 및 그를 포함하는 약학적 조성물 |
| US7507787B2 (en) * | 2001-12-03 | 2009-03-24 | The University Of British Columbia | Effectors of innate immunity |
| US20030125662A1 (en) * | 2002-01-03 | 2003-07-03 | Tuan Bui | Method and apparatus for providing medical treatment therapy based on calculated demand |
| US20030219854A1 (en) * | 2002-03-21 | 2003-11-27 | Micrologix Biotech Inc. | Methods for producing modified anti-infective peptides |
| ATE489462T1 (de) * | 2002-04-25 | 2010-12-15 | Toagosei Co Ltd | Antimikrobielles polypeptid und nutzung davon |
| US7119070B2 (en) | 2002-04-30 | 2006-10-10 | The Regents Of The University Of California | Antimicrobial theta defensins, analogs thereof, and methods of use |
| US7033769B2 (en) * | 2002-05-23 | 2006-04-25 | The United States Of America As Represented By The Secretary Of The Army | Method for discovering one or more peptides adapted for specific binding to a microorganism of interest |
| US7238164B2 (en) * | 2002-07-19 | 2007-07-03 | Baxter International Inc. | Systems, methods and apparatuses for pumping cassette-based therapies |
| WO2005019241A2 (en) * | 2003-08-18 | 2005-03-03 | E.I. Dupont De Nemours And Company | Cationic antimicrobial peptides and compositions thereof |
| US7674771B2 (en) * | 2003-10-29 | 2010-03-09 | Toagosei Co., Ltd | Antimicrobial peptides and utilization of the same |
| US20050209563A1 (en) * | 2004-03-19 | 2005-09-22 | Peter Hopping | Cassette-based dialysis medical fluid therapy systems, apparatuses and methods |
| JP4507080B2 (ja) * | 2004-07-30 | 2010-07-21 | 東亞合成株式会社 | 抗菌ペプチド及びその利用 |
| JP4730584B2 (ja) | 2004-12-06 | 2011-07-20 | 東亞合成株式会社 | 抗菌ペプチド及びその利用 |
| CN101111256B (zh) | 2004-12-15 | 2012-04-25 | 科罗拉多大学 | 抗菌肽及其使用方法 |
| US20090030179A1 (en) * | 2005-02-15 | 2009-01-29 | Toagosei Co., Ltd | Antimicrobial peptide and use thereof |
| US8558964B2 (en) | 2007-02-15 | 2013-10-15 | Baxter International Inc. | Dialysis system having display with electromagnetic compliance (“EMC”) seal |
| US8870812B2 (en) | 2007-02-15 | 2014-10-28 | Baxter International Inc. | Dialysis system having video display with ambient light adjustment |
| US8361023B2 (en) * | 2007-02-15 | 2013-01-29 | Baxter International Inc. | Dialysis system with efficient battery back-up |
| US7998115B2 (en) * | 2007-02-15 | 2011-08-16 | Baxter International Inc. | Dialysis system having optical flowrate detection |
| US7731689B2 (en) | 2007-02-15 | 2010-06-08 | Baxter International Inc. | Dialysis system having inductive heating |
| CA2694046C (en) * | 2007-07-26 | 2023-09-12 | Revance Therapeutics, Inc. | Cationic peptides and compositions thereof |
| EP2346521A4 (en) * | 2008-10-06 | 2012-06-20 | Univ Colorado Regents | PEPTIDES AND USE METHOD THEREFOR |
| GB0821616D0 (en) * | 2008-11-26 | 2008-12-31 | Lytix Biopharma As | Compounds |
| EP2437770A4 (en) * | 2009-06-05 | 2013-11-06 | Univ Colorado Regents | ANTIMICROBIAL PEPTIDES |
| WO2011068801A2 (en) | 2009-12-01 | 2011-06-09 | The Rockefeller University | Methods for identifying compounds that modulate ion channel activity of a kir channel |
| EP3540059A1 (en) | 2010-04-16 | 2019-09-18 | Nuevolution A/S | Bi-functional complexes and methods for making and using such complexes |
| WO2013039861A2 (en) | 2011-09-12 | 2013-03-21 | modeRNA Therapeutics | Engineered nucleic acids and methods of use thereof |
| WO2013151665A2 (en) | 2012-04-02 | 2013-10-10 | modeRNA Therapeutics | Modified polynucleotides for the production of proteins associated with human disease |
| CN104411338A (zh) | 2012-04-02 | 2015-03-11 | 现代治疗公司 | 用于产生与人类疾病相关的生物制剂和蛋白质的修饰多核苷酸 |
| US20150072922A1 (en) * | 2012-04-17 | 2015-03-12 | The Research Institute At Nationwide Children's Hospital | Rnase 7 antimicrobial peptides |
| MY151307A (en) * | 2012-06-18 | 2014-05-05 | Univ Malaya | Peptides having antimicrobial activity |
| GB201401877D0 (en) | 2014-02-04 | 2014-03-19 | Univ Tromsoe | Peptides |
| EP3067608A1 (en) * | 2015-03-10 | 2016-09-14 | Abu Dhabi Polymers Co. Ltd (Borouge) LLC. | Eccentric polyolefin pipe |
| WO2017083515A2 (en) | 2015-11-10 | 2017-05-18 | Visterra, Inc. | Antibody molecule-drug conjugates and uses thereof |
| JP7303110B2 (ja) | 2017-01-18 | 2023-07-04 | ビステラ， インコーポレイテッド | 抗体分子－薬物コンジュゲートおよびその使用 |
| WO2018160791A1 (en) | 2017-03-03 | 2018-09-07 | Massachusetts Institute Of Technology | Antimicrobial constructs and uses thereof |
| US10934943B2 (en) | 2017-04-27 | 2021-03-02 | General Electric Company | Compressor apparatus with bleed slot and supplemental flange |
| US11179516B2 (en) | 2017-06-22 | 2021-11-23 | Baxter International Inc. | Systems and methods for incorporating patient pressure into medical fluid delivery |
| KR20240085798A (ko) | 2020-04-03 | 2024-06-17 | 비스테라, 인크. | 항체 분자-약물 접합체 및 이의 용도 |
| CU24750B1 (es) * | 2020-11-19 | 2025-06-11 | Centro De Investig Y Desarrollo De Medicamentos Cidem | Entidades peptídicas con actividad antimicrobiana frente a patógenos multi-drogoresistentes |
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| US5028530A (en) | 1985-01-28 | 1991-07-02 | Xoma Corporation | AraB promoters and method of producing polypeptides, including cecropins, by microbiological techniques |
| US5206154A (en) | 1985-01-28 | 1993-04-27 | Xoma Corporation | Method of producing cecropins by microbiological techniques |
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| SE8802939D0 (sv) | 1988-08-19 | 1988-08-19 | Kabigen Ab | A method for the production and isolation of a fusion protein in eukaryotic cells |
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| US5217956A (en) | 1988-10-21 | 1993-06-08 | The Children's Hospital Of Philadelphia | Composition and treatment with biologically active peptides and certain anions |
| CA2007913A1 (en) | 1989-01-30 | 1990-07-30 | Michael Zasloff | Composition and treatment with peptide combinations |
| US5254535A (en) | 1989-04-17 | 1993-10-19 | The Children's Hospital Of Pennsylvania | Composition and treatment with biologically active peptides and antibiotic |
| FR2646777B1 (fr) | 1989-05-12 | 1993-09-03 | Bio Serae Lab | Procede de preparation d'un produit particulaire antimicrobien, produit antimicrobien obtenu et applications |
| US5073542A (en) | 1989-06-07 | 1991-12-17 | Magainin Sciences Inc. | CPF peptide compositions and their use in inhibiting growth of target cells or a virus |
| US5045531A (en) | 1989-12-18 | 1991-09-03 | Magainin Sciences Inc. | Wound treatment employing biologically active ion channel forming peptides and proteins |
| JPH07504152A (ja) | 1990-02-08 | 1995-05-11 | マゲイニン ファーマスーティカルズ， インコーポレーテッド | 生物活性ペプチドおよび標的細胞、ウイルス、あるいはウイルス感染細胞の成長を抑制する方法 |
| US5227469A (en) | 1990-02-14 | 1993-07-13 | Genentech, Inc. | Platelet aggregation inhibitors from the leech |
| EP0528861A4 (en) | 1990-04-23 | 1993-07-28 | Magainin Sciences, Inc. | Composition and treatment with biologically active peptides and toxic cations |
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| JPH05507273A (ja) | 1990-05-14 | 1993-10-21 | マゲイニン サイエンセズ インコーポレーテッド | Ｄアミノ酸残基を有する生物活性ペプチドの組成物およびそれによる治療方法 |
| US5208220A (en) | 1990-06-27 | 1993-05-04 | Magainin Pharmaceuticals, Inc. | Composition and treatment with biologically active peptides and antibiotics which inhibit DNA gyrase |
| US5202420A (en) | 1990-10-25 | 1993-04-13 | The Children's Hospital Of Philadelphia | Tracheal antimicrobial peptides, dna sequences and methods for the production and use thereof |
| US5235038A (en) | 1991-01-22 | 1993-08-10 | Torry Pines Institute For Molecular Studies | Deletion and substitution analogues of melittin peptide |
| CA2107674A1 (en) | 1991-04-08 | 1992-10-09 | W. Lee Maloy | Novel peptide compositions and uses therefor |
| JPH06511234A (ja) | 1991-06-12 | 1994-12-15 | マゲイニン ファーマス−ティカルズ，インコーポレーテッド | Ｃ末端置換を有する生物活性ペプチド組成物および治療法 |
| AU667479B2 (en) | 1991-06-12 | 1996-03-28 | Magainin Pharmaceuticals, Inc. | Treating the oral cavity with ion-channel forming peptides |
| US5324716A (en) * | 1991-06-14 | 1994-06-28 | Regents Of The University Of California | Broad spectrum antimicrobial compounds and methods of use |
| US5547939A (en) * | 1991-06-14 | 1996-08-20 | The Regents Of The University Of California | Broad spectrum antimicrobial compounds and methods of use |
| CA2118939A1 (en) | 1991-09-13 | 1993-04-01 | W. Lee Maloy | Biologically active amphiphilic peptide compositions and uses thereof |
| WO1993011783A1 (en) | 1991-12-09 | 1993-06-24 | Magainin Pharmaceuticals Inc. | Composition and treatment with biologically active peptides and chelating agents |
| AU674525B2 (en) | 1992-06-01 | 1997-01-02 | Magainin Pharmaceuticals, Inc. | Biologically active peptides having N-terminal substitutions |
| ATE233817T1 (de) * | 1992-08-21 | 2003-03-15 | Univ British Columbia | Kationische peptide und verfahren zu deren herstellung |
| CA2106720C (en) | 1992-09-23 | 1997-12-16 | Charles L. Deschenes | Needle for use as part of a plastic fastener dispensing tool |
| US5635594A (en) * | 1994-03-11 | 1997-06-03 | University Of California, Los Angeles | Gallinacins - antibiotic peptides |
| US5877274A (en) * | 1995-06-02 | 1999-03-02 | University Of British Columbia | Antimicrobial cationic peptides |
-
1996
- 1996-08-23 DE DE69637731T patent/DE69637731D1/de not_active Expired - Lifetime
- 1996-08-23 WO PCT/IB1996/000996 patent/WO1997008199A2/en not_active Ceased
- 1996-08-23 ES ES96930303T patent/ES2316154T3/es not_active Expired - Lifetime
- 1996-08-23 AT AT96930303T patent/ATE412668T1/de not_active IP Right Cessation
- 1996-08-23 JP JP51006897A patent/JP3860838B2/ja not_active Expired - Fee Related
- 1996-08-23 EP EP96930303A patent/EP0846128B1/en not_active Expired - Lifetime
- 1996-08-23 AU AU69407/96A patent/AU6940796A/en not_active Abandoned
- 1996-08-23 US US08/702,054 patent/US6191254B1/en not_active Expired - Fee Related
- 1996-08-23 CA CA002230160A patent/CA2230160A1/en not_active Abandoned
-
2003
- 2003-03-28 US US10/403,104 patent/US7390873B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP3860838B2 (ja) | 2006-12-20 |
| ATE412668T1 (de) | 2008-11-15 |
| US20040019181A1 (en) | 2004-01-29 |
| EP0846128A2 (en) | 1998-06-10 |
| WO1997008199A3 (en) | 1997-09-12 |
| US7390873B2 (en) | 2008-06-24 |
| EP0846128B1 (en) | 2008-10-29 |
| AU6940796A (en) | 1997-03-19 |
| HK1011867A1 (en) | 1999-07-23 |
| ES2316154T3 (es) | 2009-04-01 |
| DE69637731D1 (de) | 2008-12-11 |
| US6191254B1 (en) | 2001-02-20 |
| JPH11511971A (ja) | 1999-10-19 |
| WO1997008199A2 (en) | 1997-03-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |