CA2223414A1 - Acides d'heteroaryle diol antagonistes des leucotrienes - Google Patents
Acides d'heteroaryle diol antagonistes des leucotrienesInfo
- Publication number
- CA2223414A1 CA2223414A1 CA002223414A CA2223414A CA2223414A1 CA 2223414 A1 CA2223414 A1 CA 2223414A1 CA 002223414 A CA002223414 A CA 002223414A CA 2223414 A CA2223414 A CA 2223414A CA 2223414 A1 CA2223414 A1 CA 2223414A1
- Authority
- CA
- Canada
- Prior art keywords
- heteroaryl
- leukotriene antagonists
- diol
- acids
- diol acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 Heteroaryl diol acids Chemical class 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 239000003199 leukotriene receptor blocking agent Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 206010002383 Angina Pectoris Diseases 0.000 abstract 1
- 208000037487 Endotoxemia Diseases 0.000 abstract 1
- 206010018364 Glomerulonephritis Diseases 0.000 abstract 1
- 208000005392 Spasm Diseases 0.000 abstract 1
- 206010046851 Uveitis Diseases 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 230000001088 anti-asthma Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000000924 antiasthmatic agent Substances 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000001120 cytoprotective effect Effects 0.000 abstract 1
- 208000006454 hepatitis Diseases 0.000 abstract 1
- 231100000283 hepatitis Toxicity 0.000 abstract 1
- 150000002617 leukotrienes Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US475,139 | 1995-06-07 | ||
| US08/475,139 US5750539A (en) | 1995-06-07 | 1995-06-07 | Heteroaryl diol acids as leukotriene antagonists |
| PCT/US1996/008446 WO1996040638A1 (fr) | 1995-06-07 | 1996-06-03 | Acides d'heteroaryle diol antagonistes des leucotrienes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2223414A1 true CA2223414A1 (fr) | 1996-12-19 |
| CA2223414C CA2223414C (fr) | 2007-08-14 |
Family
ID=38434464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002223414A Expired - Fee Related CA2223414C (fr) | 1995-06-07 | 1996-06-03 | Acides d'heteroaryle diol antagonistes des leucotrienes |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2223414C (fr) |
-
1996
- 1996-06-03 CA CA002223414A patent/CA2223414C/fr not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2223414C (fr) | 2007-08-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |