CA2222066A1 - Hemodilution facilitated by monitoring oxygenation status - Google Patents

Hemodilution facilitated by monitoring oxygenation status Download PDF

Info

Publication number
CA2222066A1
CA2222066A1 CA002222066A CA2222066A CA2222066A1 CA 2222066 A1 CA2222066 A1 CA 2222066A1 CA 002222066 A CA002222066 A CA 002222066A CA 2222066 A CA2222066 A CA 2222066A CA 2222066 A1 CA2222066 A1 CA 2222066A1
Authority
CA
Canada
Prior art keywords
patient
blood
oxygen carrier
biocompatible
oxygenation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002222066A
Other languages
English (en)
French (fr)
Inventor
Nicholas Simon Faithfull
Peter E. Keipert
Duane J. Roth
Ronald M. Hopkins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alliance Pharmaceutical Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2222066A1 publication Critical patent/CA2222066A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41—Porphyrin- or corrin-ring-containing peptides
    • A61K38/42—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A61K31/025—Halogenated hydrocarbons carbocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • External Artificial Organs (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002222066A 1995-06-07 1996-06-07 Hemodilution facilitated by monitoring oxygenation status Abandoned CA2222066A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/484,166 US5865784A (en) 1995-06-07 1995-06-07 Method of hemodilution facilitated by monitoring oxygenation status
US08/484,166 1995-06-07

Publications (1)

Publication Number Publication Date
CA2222066A1 true CA2222066A1 (en) 1996-12-19

Family

ID=23923030

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002222066A Abandoned CA2222066A1 (en) 1995-06-07 1996-06-07 Hemodilution facilitated by monitoring oxygenation status

Country Status (13)

Country Link
US (3) US5865784A (enExample)
EP (1) EP0831890A1 (enExample)
JP (1) JPH11507378A (enExample)
KR (1) KR19990022355A (enExample)
CN (2) CN1720904A (enExample)
AU (1) AU717317B2 (enExample)
CA (1) CA2222066A1 (enExample)
HU (1) HUP9802266A3 (enExample)
IL (1) IL122239A0 (enExample)
NO (1) NO975318L (enExample)
PL (1) PL323937A1 (enExample)
WO (1) WO1996040222A1 (enExample)
ZA (1) ZA964656B (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6676900B1 (en) 1994-12-09 2004-01-13 Therox, Inc. Method for the preparation and delivery of gas-enriched fluids
US6180059B1 (en) * 1995-06-05 2001-01-30 Therox, Inc. Method for the preparation and delivery of gas-enriched fluids
US5865784A (en) 1995-06-07 1999-02-02 Alliance Pharmaceutical Corp. Method of hemodilution facilitated by monitoring oxygenation status
WO1999053287A2 (en) * 1998-04-09 1999-10-21 California Institute Of Technology Electronic techniques for analyte detection
GB2343679A (en) * 1998-11-16 2000-05-17 Alison Miriam Davies Autologous transplantation and method for making cells dormant
US6884228B2 (en) 2001-03-06 2005-04-26 Baxter International Inc. Automated system adaptable for use with different fluid circuits
US6706008B2 (en) 2001-03-06 2004-03-16 Baxter International Inc. Automated system and method for withdrawing compounds from blood
US6808503B2 (en) 2001-03-06 2004-10-26 Baxter International Inc. Automated system and method for pre-surgical blood donation and fluid replacement
US6582386B2 (en) 2001-03-06 2003-06-24 Baxter International Inc. Multi-purpose, automated blood and fluid processing systems and methods
US6811778B2 (en) * 2001-09-10 2004-11-02 Biopure Corporation Method for improving oxygen transport by stored red blood cells
US20070160645A1 (en) * 2001-10-25 2007-07-12 Jakob Vinten-Johansen PostConditioning System And Method For The Reduction Of Ischemic-Reperfusion Injury In The Heart And Other Organs
ATE411058T1 (de) 2001-10-25 2008-10-15 Univ Emory Katheter für modifizierte perfusion
US7241307B2 (en) * 2001-12-31 2007-07-10 Medcool, Inc. Method and apparatus for managing temperature in a patient
JP4773098B2 (ja) * 2003-01-23 2011-09-14 ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド 呼気を用いる静脈薬剤濃度をモニタするための方法および装置
EP2034959B1 (en) * 2006-05-22 2017-01-11 Alliance Pharmaceutical Corp Optimized fluorocarbon emulsions for blood substitutes and other therapeutic uses
US20100093873A1 (en) * 2008-10-02 2010-04-15 Goldfischer Sidney L Methods of improving therapy of perfluorocarbons (PFC)
US8636952B2 (en) * 2008-12-04 2014-01-28 Therox, Inc. System for enriching a bodily fluid with a gas having a removable gas-enrichment device with an information recording element
US20100143190A1 (en) * 2008-12-04 2010-06-10 Therox, Inc. System for enriching a bodily fluid with a gas having occlusion detection capabilities
US8192384B2 (en) * 2008-12-04 2012-06-05 Therox, Inc. System for enriching a bodily fluid with a gas having a dual-function power switch mechanism
US8246564B2 (en) * 2008-12-04 2012-08-21 Therox, Inc. System for enriching a bodily fluid with a gas having automated priming capabilities
US20100143192A1 (en) * 2008-12-04 2010-06-10 Therox, Inc. Method and device for combined detection of bubbles and flow rate in a system for enriching a bodily fluid with a gas
US7989593B1 (en) 2010-05-27 2011-08-02 Bing Lou Wong Method for the preparation of a high-temperature stable oxygen-carrier-containing pharmaceutical composition and the use thereof
US8048856B1 (en) 2010-06-23 2011-11-01 Billion King, Ltd. Treatment methods using a heat stable oxygen carrier-containing pharmaceutical composition
US7932356B1 (en) 2010-06-23 2011-04-26 Bing Lou Wong Method for the preparation of a heat stable oxygen carrier-containing pharmaceutical composition
US8084581B1 (en) 2011-04-29 2011-12-27 Bing Lou Wong Method for removing unmodified hemoglobin from cross-linked hemoglobin solutions including polymeric hemoglobin with a high temperature short time heat treatment apparatus
US20130052232A1 (en) 2011-08-31 2013-02-28 Bing Lou Wong Method for the preparation of a heat stable oxygen carrier-containing composition facilating beta-beta cross-linking
CN108380965B (zh) * 2013-04-04 2021-02-19 米沃奇电动工具公司 电动工具
GB2540724A (en) 2015-03-06 2017-02-01 Spectrum Medical Ltd Blood analysis apparatus and method
FR3097770B1 (fr) * 2019-06-27 2024-03-01 I Sep Système et procédé de traitement de liquide hémorragique pour de l’autotransfusion
CN111135360A (zh) * 2020-01-21 2020-05-12 广州弘大医疗科技有限公司 一种右心辅助装置及其控制方法
CN116370633A (zh) * 2023-04-21 2023-07-04 中国药科大学 一种包载全氟己烷和抗氧化剂的纳米脂质制剂及其制备方法与制备治疗心肌梗死药物的应用

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3482575A (en) 1967-02-16 1969-12-09 Single Cell Research Foundatio Method for the extracorporeal oxygenation of blood
US3958014A (en) 1970-09-05 1976-05-18 The Green Cross Corporation Process for preparing injection-purpose fluorocarbon emulsion capable of carrying oxygen
US3975512A (en) * 1970-12-21 1976-08-17 University Of Illinois Foundation Non-toxic brominated perfluorocarbons radiopaque agents
US4073879A (en) * 1974-08-26 1978-02-14 University Of Illinois Foundation Brominated perfluorocarbon radiopaque agents
DE2754894C2 (de) 1977-12-09 1983-10-13 Fresenius AG, 6380 Bad Homburg Vorrichtung zum Bilanzieren einer einem Patienten entnommenen Flüssigkeit mit einer Ersatzflüssigkeit
DE3049665T1 (de) 1979-06-25 1982-03-18 Suntech Use of perfluorocarbon as burn treatment
JPS6023084B2 (ja) * 1979-07-11 1985-06-05 味の素株式会社 代用血液
US4981691A (en) 1980-04-14 1991-01-01 Thomas Jefferson University Oxygenated fluorocarbon nutrient solution
US4657532A (en) 1985-07-19 1987-04-14 Thomas Jefferson University Intra-peritoneal perfusion of oxygenated fluorocarbon
FR2515198A1 (fr) 1981-10-22 1983-04-29 Centre Nat Rech Scient Microemulsions aqueuses de fluorocarbures indefiniment stables a une temperature donnee, procede d'obtention et application a titre de transporteurs d'oxygene
JPS5832829A (ja) 1981-08-22 1983-02-25 Green Cross Corp:The 血管造影剤
DE3144705C2 (de) * 1981-11-11 1983-12-08 Biotest-Serum-Institut Gmbh, 6000 Frankfurt Verfahren zur Herstellung eines lagerstabilen, vernetzten Hämoglobinpräparates mit hoher Sauerstoff-Transportkapazität, sowie das nach diesem Verfahren hergestellte Hämoglobinpräparat
US4425334A (en) 1982-04-02 1984-01-10 The Regents Of The University Of California Functional oxygen transport system
US4473494A (en) * 1983-05-04 1984-09-25 The United States Of America As Represented By The Secretary Of The Army Preparation of stroma-free, non-heme protein-free hemoglobin
DE3340592A1 (de) * 1983-11-10 1985-05-23 B. Braun Melsungen Ag, 3508 Melsungen Konjugate makromolekularer verbindungen an haemoglobine, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
JPS60166626A (ja) 1984-02-09 1985-08-29 Green Cross Corp:The 血管造影剤
DE3412144A1 (de) * 1984-03-31 1985-10-10 Biotest Pharma GmbH, 6000 Frankfurt Verfahren zur herstellung hochgereinigter, stromafreier, hepatitissicherer human- und tierhaemoglobinloesungen
US4600531A (en) * 1984-06-27 1986-07-15 University Of Iowa Research Foundation Production of alpha-alpha cross-linked hemoglobins in high yield
US4987154A (en) * 1986-01-14 1991-01-22 Alliance Pharmaceutical Corp. Biocompatible, stable and concentrated fluorocarbon emulsions for contrast enhancement and oxygen transport in internal animal use
US4927623A (en) 1986-01-14 1990-05-22 Alliance Pharmaceutical Corp. Dissolution of gas in a fluorocarbon liquid
US5080885A (en) 1986-01-14 1992-01-14 Alliance Pharmaceutical Corp. Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport
US4865836A (en) * 1986-01-14 1989-09-12 Fluoromed Pharmaceutical, Inc. Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport
US4911929A (en) * 1986-08-29 1990-03-27 The United States Of America As Represented By The Secretary Of The Navy Blood substitute comprising liposome-encapsulated hemoglobin
US4861667A (en) 1986-12-19 1989-08-29 Asahi Glass Company, Ltd. Coating composition and coated product
GB8710598D0 (en) * 1987-05-05 1987-06-10 Star Medical Diagnostics Ltd Hemoglobin based blood substitute
US4861867A (en) * 1988-02-03 1989-08-29 Baxter International, Inc. Purified hemoglobin solutions and method for making same
US5130230A (en) 1988-05-02 1992-07-14 Cryomedical Sciences, Inc. Blood substitute
US4911999A (en) 1988-12-13 1990-03-27 E. I. Du Pont De Nemours And Company Electrostatic master containing thiourea or thioamide electrostatic decay additive for high speed xeroprinting
US5344393A (en) 1992-02-28 1994-09-06 Alliance Pharmaceutical Corp. Use of synthetic oxygen carriers to facilitate oxygen delivery
US5865784A (en) 1995-06-07 1999-02-02 Alliance Pharmaceutical Corp. Method of hemodilution facilitated by monitoring oxygenation status

Also Published As

Publication number Publication date
AU717317B2 (en) 2000-03-23
HUP9802266A3 (en) 2001-03-28
AU6271396A (en) 1996-12-30
NO975318D0 (no) 1997-11-19
ZA964656B (en) 1997-02-28
CN1192155A (zh) 1998-09-02
CN1720904A (zh) 2006-01-18
US5865784A (en) 1999-02-02
EP0831890A1 (en) 1998-04-01
HUP9802266A2 (hu) 1999-02-01
JPH11507378A (ja) 1999-06-29
USRE38081E1 (en) 2003-04-15
KR19990022355A (ko) 1999-03-25
IL122239A0 (en) 1998-04-05
NO975318L (no) 1998-01-30
PL323937A1 (en) 1998-04-27
WO1996040222A1 (en) 1996-12-19
US6007774A (en) 1999-12-28

Similar Documents

Publication Publication Date Title
CA2222066A1 (en) Hemodilution facilitated by monitoring oxygenation status
US5451205A (en) Facilitated oxygen delivery in conjunction with hemodilution
Keipert Use of Oxygent™, a perfluorochemical-based oxygen carrier, as an alternative to intraoperative blood transfusion
Faithfull Oxygen delivery from fluorocarbon emulsions-aspects of convective and diffusive transport
Hill Perfluorocarbons: knowledge gained from clinical trials
CA2076009C (en) System and method for oxygenation of the heart using subpericardial fluids
Rude et al. Effects of intravenous fluorocarbons during and without oxygen enhancement on acute myocardial ischemic injury assessed by measurement of intramyocardial gas tensions
US5869538A (en) Method for enhancing transport of gases to tissues
Goodin et al. A perfluorochemical emulsion for prehospital resuscitation of experimental hemorrhagic shock: a prospective, randomized, controlled study
Waxman et al. Perfluorocarbon infusion in bleeding patients refusing blood transfusions
Waxman Perfluorocarbons as blood substitutes
Lane Perfluorochemical-based artificial oxygen carrying red cell substitutes
Henry et al. The effect of experimental hemorrhagic shock on pulmonary alveolar surfactant
Lieberthal et al. Ischemia in the isolated erythrocyte-perfused rat kidney: protective effect of hypothermia
Ohyanagi et al. Development and clinical application of perfluorochemical artificial blood
Clark et al. Perfluorocarbons: future clinical possibilities
CA2315877C (en) Facilitated oxygen delivery in conjunction with hemodilution
Standl Artificial oxygen carriers as red blood cell substitutes–perfluorocarbons and cell-free hemoglobin
Faithfull et al. Tissue oxygenation by fluorocarbons
MXPA97009697A (es) Hemodulacion facilitada por el monitoreo de la condicion de oxigenacion
HK1010448B (en) Facilitated oxygen delivery in conjunction with hemodilution
AU4264100A (en) Hemodilution facilitated by mounting oxygenation status
CA2085475A1 (en) Hyperosmotic solutions for isonatremic resuscitation
Agishi et al. (Pyridoxalated Hemoglobin)-(Polyoxyethylene) Conjugate Solution as Blood Substitute for Normothermic Whole Body Rinse-Out
Brown et al. Fluosol-DA, a perfluorochemical oxygen-transport fluid for the management of a trochanteric pressure sore in a Jehovah’s Witness

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued