CA2218370C - Comprime a macher a action effervescente - Google Patents
Comprime a macher a action effervescente Download PDFInfo
- Publication number
- CA2218370C CA2218370C CA002218370A CA2218370A CA2218370C CA 2218370 C CA2218370 C CA 2218370C CA 002218370 A CA002218370 A CA 002218370A CA 2218370 A CA2218370 A CA 2218370A CA 2218370 C CA2218370 C CA 2218370C
- Authority
- CA
- Canada
- Prior art keywords
- weight
- chewable tablet
- effervescent
- tablet according
- tablet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
Abstract
L'invention concerne un comprimé à mâcher contenant une base effervescente en faible quantité (qui produit un picotement agréable dans la bouche), des constituants actifs et des charges dans des proportions telles que le comprimé se dissolve quand même - à l'exception des constituants actifs insolubles ou peu solubles - dans 100 ml d'eau à température comprise entre 15 et 20 DEG C en moins de 120 secondes, de préférence en 90 secondes maximum. Pour ce faire, l'invention propose que les particules d'acide et/ou de carbonate de la base effervescente soient recouvertes d'un hydrocolloïde - de préférence facilement ou rapidement soluble - et/ou que le constituant actif soit exempt de substances d'encapsulage et que le mélange du comprimé soit exempt de lubrifiants. Le comprimé a un poids compris entre 600 et 1500 mg seulement, de préférence entre 700 et 1200 mg.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH223095 | 1995-07-31 | ||
CH2230/95-3 | 1995-07-31 | ||
PCT/EP1996/003165 WO1997004754A1 (fr) | 1995-07-31 | 1996-07-18 | Comprime a macher a action effervescente |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2218370A1 CA2218370A1 (fr) | 1997-02-13 |
CA2218370C true CA2218370C (fr) | 2006-10-03 |
Family
ID=37101767
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002218370A Expired - Lifetime CA2218370C (fr) | 1995-07-31 | 1996-07-18 | Comprime a macher a action effervescente |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2218370C (fr) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8092832B2 (en) | 2003-12-31 | 2012-01-10 | Cephalon, Inc. | Generally linear effervescent oral fentanyl dosage form and methods of administering |
US8119158B2 (en) | 2003-12-31 | 2012-02-21 | Cephalon, Inc. | Effervescent oral fentanyl dosage form and methods of administering fentanyl |
US8298577B2 (en) | 2003-12-31 | 2012-10-30 | Cephalon, Inc. | Effervescent oral opiate dosage forms and methods of administering opiates |
US8728441B2 (en) | 1998-03-27 | 2014-05-20 | Cephalon, Inc. | Sublingual buccal effervescent |
US8802130B2 (en) | 1998-03-27 | 2014-08-12 | Cephalon, Inc. | Sublingual buccal effervescent |
-
1996
- 1996-07-18 CA CA002218370A patent/CA2218370C/fr not_active Expired - Lifetime
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8728441B2 (en) | 1998-03-27 | 2014-05-20 | Cephalon, Inc. | Sublingual buccal effervescent |
US8753611B2 (en) | 1998-03-27 | 2014-06-17 | Cephalon, Inc. | Sublingual buccal effervescent |
US8765100B2 (en) | 1998-03-27 | 2014-07-01 | Cephalon, Inc. | Transmucosal effervescent |
US8802130B2 (en) | 1998-03-27 | 2014-08-12 | Cephalon, Inc. | Sublingual buccal effervescent |
US8092832B2 (en) | 2003-12-31 | 2012-01-10 | Cephalon, Inc. | Generally linear effervescent oral fentanyl dosage form and methods of administering |
US8119158B2 (en) | 2003-12-31 | 2012-02-21 | Cephalon, Inc. | Effervescent oral fentanyl dosage form and methods of administering fentanyl |
US8298577B2 (en) | 2003-12-31 | 2012-10-30 | Cephalon, Inc. | Effervescent oral opiate dosage forms and methods of administering opiates |
Also Published As
Publication number | Publication date |
---|---|
CA2218370A1 (fr) | 1997-02-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |
Effective date: 20160718 |