CA2211794A1 - Iontophoresis device for the transcutaneous delivery of an active principle such as an anionic oligosaccharide - Google Patents
Iontophoresis device for the transcutaneous delivery of an active principle such as an anionic oligosaccharideInfo
- Publication number
- CA2211794A1 CA2211794A1 CA002211794A CA2211794A CA2211794A1 CA 2211794 A1 CA2211794 A1 CA 2211794A1 CA 002211794 A CA002211794 A CA 002211794A CA 2211794 A CA2211794 A CA 2211794A CA 2211794 A1 CA2211794 A1 CA 2211794A1
- Authority
- CA
- Canada
- Prior art keywords
- active principle
- electrodes
- electrode
- anionic oligosaccharide
- iontophoresis device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
Le dispositif comporte une électrode négative réversible, en contact avec un élément réservoir contenant un électrolyte renfermant le principe actif oligosaccharide anionique, notamment pentasaccharide, sous une forme au moins partiellement ionisée, une électrode positive, seule ou associée à un réceptacle contenant un électrolyte, et un générateur de signaux électriques connectable aux deux électrodes. Le générateur est agencé pour appliquer, entre les électrodes, des signaux électriques de tension moyenne telle que la densité du courant moyen généré entre les électrodes est comprise entre 0,05 et 0.25 mA/cm2. La quantité de principe actif présente dans l'élément réservoir associé à l'électrode négative représente 0,5 mg à 12 mg par cm2 d'électrode et par mAh de courant passant par cm2 d'électrode.The device comprises a reversible negative electrode, in contact with a reservoir element containing an electrolyte containing the active principle anionic oligosaccharide, in particular pentasaccharide, in an at least partially ionized form, a positive electrode, alone or associated with a receptacle containing an electrolyte, and an electrical signal generator connectable to the two electrodes. The generator is arranged to apply, between the electrodes, electrical signals of medium voltage such that the density of the average current generated between the electrodes is between 0.05 and 0.25 mA / cm2. The quantity of active principle present in the reservoir element associated with the negative electrode represents 0.5 mg to 12 mg per cm2 of electrode and per mAh of current passing through cm2 of electrode.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9500757A FR2729574B1 (en) | 1995-01-24 | 1995-01-24 | IONOPHORESIS DEVICE FOR THE TRANSCUTANEOUS ADMINISTRATION OF AN ANIONIC OLIGOSACCHARIDE ACTIVE PRINCIPLE |
| FR95/00757 | 1995-01-24 | ||
| PCT/FR1996/000114 WO1996022808A1 (en) | 1995-01-24 | 1996-01-24 | Iontophoresis device for the transcutaneous delivery of an active principle such as an anionic oligosaccharide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2211794A1 true CA2211794A1 (en) | 1996-08-01 |
| CA2211794C CA2211794C (en) | 2006-06-27 |
Family
ID=36644838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002211794A Expired - Lifetime CA2211794C (en) | 1995-01-24 | 1996-01-24 | Iontophoresis device for the transcutaneous delivery of an active principle such as an anionic oligosaccharide |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2211794C (en) |
-
1996
- 1996-01-24 CA CA002211794A patent/CA2211794C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2211794C (en) | 2006-06-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |
Effective date: 20160125 |